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The map label for this gene is bcd [H]

Identifier: 119899371

GI number: 119899371

Start: 3389852

End: 3391024

Strand: Reverse

Name: bcd [H]

Synonym: azo3081

Alternate gene names: 119899371

Gene position: 3391024-3389852 (Counterclockwise)

Preceding gene: 119899373

Following gene: 119899368

Centisome position: 77.49

GC content: 64.79

Gene sequence:

>1173_bases
ATGAACATTCCCAGCCTGGACTTCAACCTCGGCGAAACCATCGAGGCCCTGCGCGACACCGTGAAGCGCTTCGCCGACGA
GGAAATCGCGCCGCGCGCCGCCGCCATCGACCAGAACAACGAATTCCCCGCCGACCTGTGGAAGAAGCTGGGCGACCTCG
GCCTGCACGGCATGACGGTGGAAGAGGAATACGGCGGCAGCGCCATGGGCTACCTCGCCCACATCATCGCGCTCGAAGAA
GTGTCGCGCGCCTCGGCCTCGGTGGGCCTCTCGTACGGCGCGCATTCCAACCTGTGCGTCAATCAGATCCGCCGCAACGG
CAACGCCGCGCAGAAGCAGAAGTACCTGCCCAAGCTGATCTCCGGCGAGCACGTGGGCGCGCTGGCGATGAGCGAGCCCA
ACGCCGGTTCCGACGTCGTCAGCATGAAGCTGCGCGCCGACAAGAAGGGCGACCGCTACGTGCTCAACGGCAGCAAGATG
TGGATCACCAACGGCGGCGACGCCGACACGCTGGTGGTCTATGCCAAGACCGACATCAACGCCGGCCCGAAGGGCATGAC
GGCCTTCATCATCGAGAAGGGGATGAAGGGCTTCAGCCACGGCACCCATCTCGACAAGCTCGGCATGCGCGGCTCCAACA
CCTTCCCGCTGTTCTTCGACGATGTCGAGGTGCCGGAAGAGAACGTGCTGGGCGGCGTCGGCAACGGCGCAAGAGTGCTG
ATGAGCGGGCTGGACTACGAACGCGCGGTGCTGTGCGGCGGCCCGCTGGGCATCATGGCCGCCTGCATGGACGTGGTGGT
GCCCTACCTGCACGAGCGCAAGCAGTTCGGCCAGAGCATCGGCGAATTCCAGCTGATGCAGGGCAAGCTTGCCGACATGT
ACTCCACCTGGATGGCCACCCGCGCCTATGTGTACGCGGTGGGCCAGGCCTGCGACCGCACCGACCACGCCCGCACGCTG
CGCAAGGACGCCGCCGGCGCGATTCTGTATTCGGCGGAAAAGGCCACCTGGATGGCGGGCGAAGCAATCCAGACGCTGGG
CGGCGTCGGCTATACCAATGAATATTCCACCGGTCGGCTGTGGCGCGATGCCAAGCTGTATGAAATTGGCGCGGGCACGA
GCGAAATCCGCCGGATGTTGATCGGGCGGGAATTGTTTGCCGAAACGGCTTGA

Upstream 100 bases:

>100_bases
ATCTTGGCGCCCGTTGCGCCAAGGGCTGGATTACGCTCGGGCCATCCGTCCCGCCGTGCCTTCGCCGCGGCGGGCACCCT
ACAGAACGAGGAGACACGCG

Downstream 100 bases:

>100_bases
TGACGTAACAGCGAGCGGGCAACGGATCGATCAACGAATTGTTGATCGACCCGCCGGAAACAAATACGGGCGCAGCAATG
CGCCCGTTTTTTTCGTCAGC

Product: acyl-coa dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNIPSLDFNLGETIEALRDTVKRFADEEIAPRAAAIDQNNEFPADLWKKLGDLGLHGMTVEEEYGGSAMGYLAHIIALEE
VSRASASVGLSYGAHSNLCVNQIRRNGNAAQKQKYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADKKGDRYVLNGSKM
WITNGGDADTLVVYAKTDINAGPKGMTAFIIEKGMKGFSHGTHLDKLGMRGSNTFPLFFDDVEVPEENVLGGVGNGARVL
MSGLDYERAVLCGGPLGIMAACMDVVVPYLHERKQFGQSIGEFQLMQGKLADMYSTWMATRAYVYAVGQACDRTDHARTL
RKDAAGAILYSAEKATWMAGEAIQTLGGVGYTNEYSTGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETA

Sequences:

>Translated_390_residues
MNIPSLDFNLGETIEALRDTVKRFADEEIAPRAAAIDQNNEFPADLWKKLGDLGLHGMTVEEEYGGSAMGYLAHIIALEE
VSRASASVGLSYGAHSNLCVNQIRRNGNAAQKQKYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADKKGDRYVLNGSKM
WITNGGDADTLVVYAKTDINAGPKGMTAFIIEKGMKGFSHGTHLDKLGMRGSNTFPLFFDDVEVPEENVLGGVGNGARVL
MSGLDYERAVLCGGPLGIMAACMDVVVPYLHERKQFGQSIGEFQLMQGKLADMYSTWMATRAYVYAVGQACDRTDHARTL
RKDAAGAILYSAEKATWMAGEAIQTLGGVGYTNEYSTGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETA
>Mature_390_residues
MNIPSLDFNLGETIEALRDTVKRFADEEIAPRAAAIDQNNEFPADLWKKLGDLGLHGMTVEEEYGGSAMGYLAHIIALEE
VSRASASVGLSYGAHSNLCVNQIRRNGNAAQKQKYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADKKGDRYVLNGSKM
WITNGGDADTLVVYAKTDINAGPKGMTAFIIEKGMKGFSHGTHLDKLGMRGSNTFPLFFDDVEVPEENVLGGVGNGARVL
MSGLDYERAVLCGGPLGIMAACMDVVVPYLHERKQFGQSIGEFQLMQGKLADMYSTWMATRAYVYAVGQACDRTDHARTL
RKDAAGAILYSAEKATWMAGEAIQTLGGVGYTNEYSTGRLWRDAKLYEIGAGTSEIRRMLIGRELFAETA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=61.6187989556136, Blast_Score=482, Evalue=1e-136,
Organism=Homo sapiens, GI226958414, Length=354, Percent_Identity=63.2768361581921, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=39.4179894179894, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI4501859, Length=372, Percent_Identity=36.5591397849462, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI21361497, Length=369, Percent_Identity=37.3983739837398, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=36.745406824147, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=35.509138381201, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4557235, Length=381, Percent_Identity=36.745406824147, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=35.509138381201, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI7656849, Length=389, Percent_Identity=32.133676092545, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=32.0855614973262, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4503943, Length=375, Percent_Identity=31.4666666666667, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI7669494, Length=349, Percent_Identity=32.378223495702, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI48976061, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI211971008, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=30.8290155440415, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1786223, Length=384, Percent_Identity=28.125, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081702, Length=272, Percent_Identity=26.1029411764706, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082384, Length=262, Percent_Identity=27.0992366412214, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=60.5744125326371, Blast_Score=470, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=35.5670103092784, Blast_Score=237, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=33.7696335078534, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=34.2465753424658, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17534899, Length=388, Percent_Identity=34.5360824742268, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=34.2783505154639, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI71990804, Length=299, Percent_Identity=39.1304347826087, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17533517, Length=380, Percent_Identity=31.8421052631579, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=33.9031339031339, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=33.0666666666667, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=35.6890459363958, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=31.3829787234043, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=37.8260869565217, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=34.5454545454545, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=29.0155440414508, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=29.2181069958848, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355753, Length=385, Percent_Identity=59.2207792207792, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=38.8451443569554, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=37.7308707124011, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=35, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=36.2694300518135, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI281363737, Length=382, Percent_Identity=34.2931937172775, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI19920834, Length=389, Percent_Identity=29.5629820051414, Blast_Score=159, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 42315; Mature: 42315

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPSLDFNLGETIEALRDTVKRFADEEIAPRAAAIDQNNEFPADLWKKLGDLGLHGMTV
CCCCCCCCCHHHHHHHHHHHHHHHHCHHCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEE
EEEYGGSAMGYLAHIIALEEVSRASASVGLSYGAHSNLCVNQIRRNGNAAQKQKYLPKLI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
SGEHVGALAMSEPNAGSDVVSMKLRADKKGDRYVLNGSKMWITNGGDADTLVVYAKTDIN
CCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEEECCCC
AGPKGMTAFIIEKGMKGFSHGTHLDKLGMRGSNTFPLFFDDVEVPEENVLGGVGNGARVL
CCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCHHHCCCCCCCCHHHH
MSGLDYERAVLCGGPLGIMAACMDVVVPYLHERKQFGQSIGEFQLMQGKLADMYSTWMAT
HHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYVYAVGQACDRTDHARTLRKDAAGAILYSAEKATWMAGEAIQTLGGVGYTNEYSTGRL
HHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCE
WRDAKLYEIGAGTSEIRRMLIGRELFAETA
ECCCEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIPSLDFNLGETIEALRDTVKRFADEEIAPRAAAIDQNNEFPADLWKKLGDLGLHGMTV
CCCCCCCCCHHHHHHHHHHHHHHHHCHHCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEE
EEEYGGSAMGYLAHIIALEEVSRASASVGLSYGAHSNLCVNQIRRNGNAAQKQKYLPKLI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
SGEHVGALAMSEPNAGSDVVSMKLRADKKGDRYVLNGSKMWITNGGDADTLVVYAKTDIN
CCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEEECCCC
AGPKGMTAFIIEKGMKGFSHGTHLDKLGMRGSNTFPLFFDDVEVPEENVLGGVGNGARVL
CCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCHHHCCCCCCCCHHHH
MSGLDYERAVLCGGPLGIMAACMDVVVPYLHERKQFGQSIGEFQLMQGKLADMYSTWMAT
HHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYVYAVGQACDRTDHARTLRKDAAGAILYSAEKATWMAGEAIQTLGGVGYTNEYSTGRL
HHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCE
WRDAKLYEIGAGTSEIRRMLIGRELFAETA
ECCCEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]