Click here to switch to the map view.

The map label for this gene is paaG4 [H]

Identifier: 119899333

GI number: 119899333

Start: 3347056

End: 3347859

Strand: Reverse

Name: paaG4 [H]

Synonym: azo3043

Alternate gene names: 119899333

Gene position: 3347859-3347056 (Counterclockwise)

Preceding gene: 119899334

Following gene: 119899332

Centisome position: 76.5

GC content: 69.03

Gene sequence:

>804_bases
ATGGACTACAGCCGCTACACCAGCCTCGAAATCGTCCGCCACGAACGCGGCGTCGTCGAACTCGTCATGGGCCGCGATGG
CAAATTGCCGGCGGCCGACCACGCCGGGCACGGCGAACTCGCCGACATCTGGCGCGACATCGACCGCGACCCCGACATCT
CGGTGGTGATCGTGCGCGGCCAGGCCAAGGGCTTTTCCGCCGGCGGCACGCTGGAACTGGTCGGCGACATGGTGGAGAGC
TTCGAGCACCGCGCCCGCGTCTGGAAGGAGGCGCGCGACATCGTGTACAACATGATCAACTGCTCCAAGATCATCGTCTC
CGCGATCAACGGTCCCGCAGTCGGCGGTGGCCTCGCGGTGGCGCTGATGGCGGACATCTCCATCGCCGCCAAGAACGCCC
GCCTGATCGACGGCCACACCCGCCTCGGCGTCGCCGCCGGGGACCACGCCGCGATGATCTGGCCGCTCTTGTGCGGCATG
GCCAAGGCCAAGCTGCACCTGCTGCTCTCCAACGAAATCTCCGGCGAGGAAGCCGAGCGCATCGGCCTGGTGTCGATGGC
GGTGGAGGCCGACGCGCTGATGGACAGCGCGCTGGAGATCGCCAACAGGCTCGCCGCCGGCCCGCAGAGCGCGCTGCGCT
GGACCAAGCACAGCCTCAACAACTGGCTGCGCCAGGCGGGGCCGATCTTCGACAACTCGGTGGCGCTGGAAATGCTCGGC
TTCACCGGCCCCGAAGTGCGCGAGGGCCTCGCCGCGGTGCGCGAGCGCCGGCCGGCGGTGTTCCCGCCCAACGCGCCGTT
CTGA

Upstream 100 bases:

>100_bases
CCGACATCGACAAGCTGCGGCCGGTGCCGATCACCGAAGAATTCTGGCGGCCGAAGTTCGCCGCCTACCTGAAACAACCG
GAACAGAAGTGAGCGCCCGC

Downstream 100 bases:

>100_bases
AACGGGGAGATCGACCATGCGCGCACTCGTCTGCCAGGAATTCGCCCCGCTCGACGCCCTGCAGGTCGGCGAACTGCCCG
ACCCGCAGCCGGCGGCCGGC

Product: putative enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MDYSRYTSLEIVRHERGVVELVMGRDGKLPAADHAGHGELADIWRDIDRDPDISVVIVRGQAKGFSAGGTLELVGDMVES
FEHRARVWKEARDIVYNMINCSKIIVSAINGPAVGGGLAVALMADISIAAKNARLIDGHTRLGVAAGDHAAMIWPLLCGM
AKAKLHLLLSNEISGEEAERIGLVSMAVEADALMDSALEIANRLAAGPQSALRWTKHSLNNWLRQAGPIFDNSVALEMLG
FTGPEVREGLAAVRERRPAVFPPNAPF

Sequences:

>Translated_267_residues
MDYSRYTSLEIVRHERGVVELVMGRDGKLPAADHAGHGELADIWRDIDRDPDISVVIVRGQAKGFSAGGTLELVGDMVES
FEHRARVWKEARDIVYNMINCSKIIVSAINGPAVGGGLAVALMADISIAAKNARLIDGHTRLGVAAGDHAAMIWPLLCGM
AKAKLHLLLSNEISGEEAERIGLVSMAVEADALMDSALEIANRLAAGPQSALRWTKHSLNNWLRQAGPIFDNSVALEMLG
FTGPEVREGLAAVRERRPAVFPPNAPF
>Mature_267_residues
MDYSRYTSLEIVRHERGVVELVMGRDGKLPAADHAGHGELADIWRDIDRDPDISVVIVRGQAKGFSAGGTLELVGDMVES
FEHRARVWKEARDIVYNMINCSKIIVSAINGPAVGGGLAVALMADISIAAKNARLIDGHTRLGVAAGDHAAMIWPLLCGM
AKAKLHLLLSNEISGEEAERIGLVSMAVEADALMDSALEIANRLAAGPQSALRWTKHSLNNWLRQAGPIFDNSVALEMLG
FTGPEVREGLAAVRERRPAVFPPNAPF

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=226, Percent_Identity=23.0088495575221, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=27.7153558052434, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI221142681, Length=206, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=24.904214559387, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=225, Percent_Identity=25.7777777777778, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=24.8062015503876, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=208, Percent_Identity=25.4807692307692, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=198, Percent_Identity=25.2525252525253, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=230, Percent_Identity=26.5217391304348, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=267, Percent_Identity=26.5917602996255, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24653477, Length=267, Percent_Identity=26.5917602996255, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24654903, Length=191, Percent_Identity=25.130890052356, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653139, Length=236, Percent_Identity=27.5423728813559, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357171, Length=241, Percent_Identity=25.7261410788382, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28774; Mature: 28774

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYSRYTSLEIVRHERGVVELVMGRDGKLPAADHAGHGELADIWRDIDRDPDISVVIVRG
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEC
QAKGFSAGGTLELVGDMVESFEHRARVWKEARDIVYNMINCSKIIVSAINGPAVGGGLAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ALMADISIAAKNARLIDGHTRLGVAAGDHAAMIWPLLCGMAKAKLHLLLSNEISGEEAER
HHHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
IGLVSMAVEADALMDSALEIANRLAAGPQSALRWTKHSLNNWLRQAGPIFDNSVALEMLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
FTGPEVREGLAAVRERRPAVFPPNAPF
CCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDYSRYTSLEIVRHERGVVELVMGRDGKLPAADHAGHGELADIWRDIDRDPDISVVIVRG
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEC
QAKGFSAGGTLELVGDMVESFEHRARVWKEARDIVYNMINCSKIIVSAINGPAVGGGLAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ALMADISIAAKNARLIDGHTRLGVAAGDHAAMIWPLLCGMAKAKLHLLLSNEISGEEAER
HHHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
IGLVSMAVEADALMDSALEIANRLAAGPQSALRWTKHSLNNWLRQAGPIFDNSVALEMLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
FTGPEVREGLAAVRERRPAVFPPNAPF
CCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]