Click here to switch to the map view.

The map label for this gene is mas [H]

Identifier: 119899332

GI number: 119899332

Start: 3346059

End: 3347039

Strand: Reverse

Name: mas [H]

Synonym: azo3042

Alternate gene names: 119899332

Gene position: 3347039-3346059 (Counterclockwise)

Preceding gene: 119899333

Following gene: 119899331

Centisome position: 76.49

GC content: 74.41

Gene sequence:

>981_bases
ATGCGCGCACTCGTCTGCCAGGAATTCGCCCCGCTCGACGCCCTGCAGGTCGGCGAACTGCCCGACCCGCAGCCGGCGGC
CGGCGAAGTCGTCATCCGCGTCTCCGCGGCCGGCATCAACTTCTACGACACCCTGATCGTGCAGGGCAAATACCAGGTGA
AGCCGGCGGCGCCGTTCTCGCCCGGCGGCGAAGTGGCCGGCACGGTCGCGGCGGTGGGCGAGGGCGTCAGCCATGTGCGG
CCGGGCGACCGCGTGTGCGCCTTCACCTCTTACGGCGGCTATGCCGAACTGTGCCGCGCCAAGGCCAGCCAGACCTGGCC
GCTGCCGGATGCGGTGGGCTTCGAGGCCGCCGCCGCCGGGCTGGTGACCTACGGCACCGCCTGGTTCGGCCTGCACGACC
GCGCCCGCATCCAGGCCGGCGAAACCGTGCTGGTGCTCGGCGCCGCCGGCGGTGTCGGCCTGGCCGCGGTGCAGATCGCC
AAGGCCGCCGGCGCGCGGGTGATCGCCGCCGCCGGCAGCGCCGAACGCCTGGCGCTGTGCCGCGAGCACGGCGCCGACGT
GCTCATCGACTACACCGCCGCCGACCTCAAGGACGCGGTCAAGGCCGCCACCGGCGGACAGGGTGCCGACATCGTCGTCG
ACGTGGTGGGCGGCGCCTACACCGAGGCCGCGCTGCGCGCCACCGCCTGGCGCGGCCGGGTGCTGATCATCGGCTTCGCC
GCCGGCGAGATCCCGCGCATTCCCGCCAACCTGCTGCTGCTGAAGGGCTGCGAGGCGTCGGGCGTGTTCTGGGACGAGCT
GATGCGGCGCGAGCCGCAGGAGGCCGCGCGCCAGGTGGCGGCGGTGCTCGACTGTTTTGCCGACGGCCGCTTGCGGCCGC
CGGTCACCGCCGCCTGCGGTCTGGGCGGCGCGGTGGATGCGATGCGCGCGCTCGCCGGCCGCCAGGTCGCGGGCAAGCTC
ATCGTGCTGCCGCAGCAATAG

Upstream 100 bases:

>100_bases
TTCACCGGCCCCGAAGTGCGCGAGGGCCTCGCCGCGGTGCGCGAGCGCCGGCCGGCGGTGTTCCCGCCCAACGCGCCGTT
CTGAAACGGGGAGATCGACC

Downstream 100 bases:

>100_bases
CTTTACCTCACTACAACACCGATACACACGGCCCCCCGGCCCAACGGAGAACGACCATGGCTCAATACCAGTGCAGCGCC
TGCTATTTCCCCTACAACGA

Product: NADPH quinone oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRALVCQEFAPLDALQVGELPDPQPAAGEVVIRVSAAGINFYDTLIVQGKYQVKPAAPFSPGGEVAGTVAAVGEGVSHVR
PGDRVCAFTSYGGYAELCRAKASQTWPLPDAVGFEAAAAGLVTYGTAWFGLHDRARIQAGETVLVLGAAGGVGLAAVQIA
KAAGARVIAAAGSAERLALCREHGADVLIDYTAADLKDAVKAATGGQGADIVVDVVGGAYTEAALRATAWRGRVLIIGFA
AGEIPRIPANLLLLKGCEASGVFWDELMRREPQEAARQVAAVLDCFADGRLRPPVTAACGLGGAVDAMRALAGRQVAGKL
IVLPQQ

Sequences:

>Translated_326_residues
MRALVCQEFAPLDALQVGELPDPQPAAGEVVIRVSAAGINFYDTLIVQGKYQVKPAAPFSPGGEVAGTVAAVGEGVSHVR
PGDRVCAFTSYGGYAELCRAKASQTWPLPDAVGFEAAAAGLVTYGTAWFGLHDRARIQAGETVLVLGAAGGVGLAAVQIA
KAAGARVIAAAGSAERLALCREHGADVLIDYTAADLKDAVKAATGGQGADIVVDVVGGAYTEAALRATAWRGRVLIIGFA
AGEIPRIPANLLLLKGCEASGVFWDELMRREPQEAARQVAAVLDCFADGRLRPPVTAACGLGGAVDAMRALAGRQVAGKL
IVLPQQ
>Mature_326_residues
MRALVCQEFAPLDALQVGELPDPQPAAGEVVIRVSAAGINFYDTLIVQGKYQVKPAAPFSPGGEVAGTVAAVGEGVSHVR
PGDRVCAFTSYGGYAELCRAKASQTWPLPDAVGFEAAAAGLVTYGTAWFGLHDRARIQAGETVLVLGAAGGVGLAAVQIA
KAAGARVIAAAGSAERLALCREHGADVLIDYTAADLKDAVKAATGGQGADIVVDVVGGAYTEAALRATAWRGRVLIIGFA
AGEIPRIPANLLLLKGCEASGVFWDELMRREPQEAARQVAAVLDCFADGRLRPPVTAACGLGGAVDAMRALAGRQVAGKL
IVLPQQ

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=32.2085889570552, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=32.2085889570552, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=32.7974276527331, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=38.423645320197, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI22538446, Length=231, Percent_Identity=32.9004329004329, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI22538444, Length=231, Percent_Identity=32.9004329004329, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI24308257, Length=239, Percent_Identity=32.2175732217573, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI28557745, Length=283, Percent_Identity=30.3886925795053, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI41872631, Length=305, Percent_Identity=28.5245901639344, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=28.7234042553192, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI47519420, Length=215, Percent_Identity=29.7674418604651, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI67078404, Length=326, Percent_Identity=25.7668711656442, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI226059159, Length=114, Percent_Identity=38.5964912280702, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI226059133, Length=114, Percent_Identity=38.5964912280702, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI226056130, Length=114, Percent_Identity=38.5964912280702, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI67078406, Length=300, Percent_Identity=25.6666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790485, Length=246, Percent_Identity=36.1788617886179, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082125, Length=294, Percent_Identity=28.2312925170068, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI226510941, Length=245, Percent_Identity=29.3877551020408, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787572, Length=188, Percent_Identity=30.3191489361702, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=238, Percent_Identity=32.7731092436975, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17536829, Length=200, Percent_Identity=31.5, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=179, Percent_Identity=27.3743016759777, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=28.2738095238095, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323961, Length=337, Percent_Identity=26.7062314540059, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=338, Percent_Identity=27.5147928994083, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=343, Percent_Identity=24.198250728863, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=315, Percent_Identity=25.0793650793651, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330659, Length=294, Percent_Identity=25.5102040816327, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920632, Length=294, Percent_Identity=25.5102040816327, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581345, Length=319, Percent_Identity=25.0783699059561, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45550423, Length=163, Percent_Identity=32.5153374233129, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 33394; Mature: 33394

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS01162 QOR_ZETA_CRYSTAL ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALVCQEFAPLDALQVGELPDPQPAAGEVVIRVSAAGINFYDTLIVQGKYQVKPAAPFS
CCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCEEECCCCCCC
PGGEVAGTVAAVGEGVSHVRPGDRVCAFTSYGGYAELCRAKASQTWPLPDAVGFEAAAAG
CCCCHHHHHHHHHCCHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
LVTYGTAWFGLHDRARIQAGETVLVLGAAGGVGLAAVQIAKAAGARVIAAAGSAERLALC
HHHHCEEEECCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHH
REHGADVLIDYTAADLKDAVKAATGGQGADIVVDVVGGAYTEAALRATAWRGRVLIIGFA
HHCCCCEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEEE
AGEIPRIPANLLLLKGCEASGVFWDELMRREPQEAARQVAAVLDCFADGRLRPPVTAACG
CCCCCCCCCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
LGGAVDAMRALAGRQVAGKLIVLPQQ
CCHHHHHHHHHHCCHHCCEEEEECCC
>Mature Secondary Structure
MRALVCQEFAPLDALQVGELPDPQPAAGEVVIRVSAAGINFYDTLIVQGKYQVKPAAPFS
CCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCEEECCCCCCC
PGGEVAGTVAAVGEGVSHVRPGDRVCAFTSYGGYAELCRAKASQTWPLPDAVGFEAAAAG
CCCCHHHHHHHHHCCHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
LVTYGTAWFGLHDRARIQAGETVLVLGAAGGVGLAAVQIAKAAGARVIAAAGSAERLALC
HHHHCEEEECCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHH
REHGADVLIDYTAADLKDAVKAATGGQGADIVVDVVGGAYTEAALRATAWRGRVLIIGFA
HHCCCCEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEEE
AGEIPRIPANLLLLKGCEASGVFWDELMRREPQEAARQVAAVLDCFADGRLRPPVTAACG
CCCCCCCCCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
LGGAVDAMRALAGRQVAGKLIVLPQQ
CCHHHHHHHHHHCCHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]