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The map label for this gene is moeB [H]

Identifier: 119899094

GI number: 119899094

Start: 3087294

End: 3088043

Strand: Reverse

Name: moeB [H]

Synonym: azo2804

Alternate gene names: 119899094

Gene position: 3088043-3087294 (Counterclockwise)

Preceding gene: 119899095

Following gene: 119899087

Centisome position: 70.57

GC content: 68.8

Gene sequence:

>750_bases
ATGAACGACGACCAGTTGCTGCGCTACAGCCGCCACATCCTGCTGCCGGAGATCGGCGTGGAAGGGCAGGAGGCGATCCT
GGCGGCGCGGGTGCTGGTCGTGGGGGCGGGCGGGCTGGGGTCGCCCGCCGCGATGTACCTGGCGGCCGCCGGCGTCGGCA
CCCTGGTGCTGGCCGATGGCGACACGGTGGACCTGACCAACCTGCAGCGCCAGATCCTGCACAGCGAAACCGGGATTGGA
AGGCCGAAGGTGGAATCGGGGCGGGACACGCTGGCGCGCCTCAATCCCCTGACCCGGGTGGAGGCACTCGCCCAGCGCCT
GGAGGGCGCTGCACTCGACGACCAGGTGGCGCTCGCGGACGTCGTCCTCGACTGTTCTGACAACTTTGCCACCCGGCATG
CAATCAACCGCGCCTGCGTGAAGCATCGCAAGCCGCTGGTGTCCGGCGCCGCGATCCGTTTCGACGGACAGGTATCGGTG
TTCGATCTGCGCAAGCCTGGCAGTCCGTGCTACCACTGCCTGTTTCCCGAGGGTGAGGACGTGGAGGAAGTGCGCTGTGC
GGTGATGGGGGTGTTCGCGCCGCTCACCGGCATCATCGGCGCCACCCAGGCGGCGGAGGCGCTGAAGCTGCTCGCAGGCT
GCGGGGAGACCTTGAATGGTCGCTTGCTGCTGCTCGATGGCCTGGCGATGGAGTGGCGCAGCGTGTCGCTCGGGCAGGAT
GCCGCTTGCGCGATGTGCGGGCAGCGCTGA

Upstream 100 bases:

>100_bases
CTGACCCCTTTGCAGCTGTGCCCATCGCACGGCTGAGCATTCCACCGCTTTTCGCCATCCCCCGGCCCGCCCTGCGTGCG
GCCGCTTTCCGGACCTTGCC

Downstream 100 bases:

>100_bases
CCGGGGTGCCGGCCTAAGCGCGCAGGCGGGCCAGGACGCGGAAGTCTTCGCCGATCCGGCGCATATCCCGGATGTCGAGC
CGCAGGGCCTGATCCAGCGA

Product: adenylyltransferase

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNDDQLLRYSRHILLPEIGVEGQEAILAARVLVVGAGGLGSPAAMYLAAAGVGTLVLADGDTVDLTNLQRQILHSETGIG
RPKVESGRDTLARLNPLTRVEALAQRLEGAALDDQVALADVVLDCSDNFATRHAINRACVKHRKPLVSGAAIRFDGQVSV
FDLRKPGSPCYHCLFPEGEDVEEVRCAVMGVFAPLTGIIGATQAAEALKLLAGCGETLNGRLLLLDGLAMEWRSVSLGQD
AACAMCGQR

Sequences:

>Translated_249_residues
MNDDQLLRYSRHILLPEIGVEGQEAILAARVLVVGAGGLGSPAAMYLAAAGVGTLVLADGDTVDLTNLQRQILHSETGIG
RPKVESGRDTLARLNPLTRVEALAQRLEGAALDDQVALADVVLDCSDNFATRHAINRACVKHRKPLVSGAAIRFDGQVSV
FDLRKPGSPCYHCLFPEGEDVEEVRCAVMGVFAPLTGIIGATQAAEALKLLAGCGETLNGRLLLLDGLAMEWRSVSLGQD
AACAMCGQR
>Mature_249_residues
MNDDQLLRYSRHILLPEIGVEGQEAILAARVLVVGAGGLGSPAAMYLAAAGVGTLVLADGDTVDLTNLQRQILHSETGIG
RPKVESGRDTLARLNPLTRVEALAQRLEGAALDDQVALADVVLDCSDNFATRHAINRACVKHRKPLVSGAAIRFDGQVSV
FDLRKPGSPCYHCLFPEGEDVEEVRCAVMGVFAPLTGIIGATQAAEALKLLAGCGETLNGRLLLLDGLAMEWRSVSLGQD
AACAMCGQR

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=251, Percent_Identity=47.0119521912351, Blast_Score=185, Evalue=3e-47,
Organism=Homo sapiens, GI4885649, Length=151, Percent_Identity=30.4635761589404, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1787048, Length=251, Percent_Identity=46.6135458167331, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI87082356, Length=248, Percent_Identity=50.8064516129032, Blast_Score=220, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17540406, Length=260, Percent_Identity=41.1538461538462, Blast_Score=187, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI193203301, Length=155, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86565433, Length=147, Percent_Identity=29.9319727891156, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86565431, Length=147, Percent_Identity=29.9319727891156, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=251, Percent_Identity=34.6613545816733, Blast_Score=145, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6322639, Length=164, Percent_Identity=26.219512195122, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=249, Percent_Identity=44.1767068273092, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24660640, Length=152, Percent_Identity=30.9210526315789, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: 2.7.7.-

Molecular weight: Translated: 26310; Mature: 26310

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDQLLRYSRHILLPEIGVEGQEAILAARVLVVGAGGLGSPAAMYLAAAGVGTLVLADG
CCCHHHHHHHHCEECCCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCEEEEECC
DTVDLTNLQRQILHSETGIGRPKVESGRDTLARLNPLTRVEALAQRLEGAALDDQVALAD
CEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHH
VVLDCSDNFATRHAINRACVKHRKPLVSGAAIRFDGQVSVFDLRKPGSPCYHCLFPEGED
HHEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCEEEEECCCCCC
VEEVRCAVMGVFAPLTGIIGATQAAEALKLLAGCGETLNGRLLLLDGLAMEWRSVSLGQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCCC
AACAMCGQR
HHHHHCCCC
>Mature Secondary Structure
MNDDQLLRYSRHILLPEIGVEGQEAILAARVLVVGAGGLGSPAAMYLAAAGVGTLVLADG
CCCHHHHHHHHCEECCCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCEEEEECC
DTVDLTNLQRQILHSETGIGRPKVESGRDTLARLNPLTRVEALAQRLEGAALDDQVALAD
CEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHH
VVLDCSDNFATRHAINRACVKHRKPLVSGAAIRFDGQVSVFDLRKPGSPCYHCLFPEGED
HHEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCEEEEECCCCCC
VEEVRCAVMGVFAPLTGIIGATQAAEALKLLAGCGETLNGRLLLLDGLAMEWRSVSLGQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCCC
AACAMCGQR
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]