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The map label for this gene is nrdR

Identifier: 119899092

GI number: 119899092

Start: 3085693

End: 3086208

Strand: Direct

Name: nrdR

Synonym: azo2802

Alternate gene names: 119899092

Gene position: 3085693-3086208 (Clockwise)

Preceding gene: 119899091

Following gene: 119899093

Centisome position: 70.51

GC content: 63.76

Gene sequence:

>516_bases
ATGAAGTGCCCCTTCTGCGACGACCCCAACACCCAGGTCACCGACACCCGTGAGAACGAGGACGGTGACGTGGTGCGTCG
CCGCCGCCGCTGCGTGAAGTGCGACAAGCGCTTCACCACCTACGAGCGGGTCGACCTGAAGATGCCGCACATCGTCAAAC
GCAACGGCAACCGCAGCGAATTCGACCACAGCAAGCTGGTCGGCAGCATGTCCCTGGCGCTGCGCAAGCGCCCGGTCACC
ACCGAAGCGCTGGAAGCCGCGGTGGACCGCATCGAGGCCAAGTTGCTGTCGCTCGGCGAAAACGAAGTGGCCAGCGAGAA
GGTCGGCGAGCTGGTGATGAAGGAGCTGAAGAAGCTCGACAAGGTGGCCTACATCCGCTTCGCTTCGGTCTATCGCAACT
TCGCCGACGTGGACGAATTCTCGGAACTCGTGCGCGAAGTACAGACACGGCCCAAGCGCGGCCGGCCTGCCAATCCCCAG
CCCTCCGGCCCTGAACATGACCTTTTCGGCGGCTGA

Upstream 100 bases:

>100_bases
AACGCGTGCGCGGCAAGGTCGGCGAGCTGTGCGCCAAGTTCCCGGTCTACGGTAGCTAAGGCAACGAGGGCCGGCCCAAG
CGCCGGCCCGACCCGCCGAC

Downstream 100 bases:

>100_bases
TCACGCCGCCATGGCGCGCGCGCTCGCGCTCGCTGCCAACGGCCTCTGTACCACCACCCCCAATCCGCGCGTCGGCTGCG
TGCTGGTACGCGACGGTGAG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKCPFCDDPNTQVTDTRENEDGDVVRRRRRCVKCDKRFTTYERVDLKMPHIVKRNGNRSEFDHSKLVGSMSLALRKRPVT
TEALEAAVDRIEAKLLSLGENEVASEKVGELVMKELKKLDKVAYIRFASVYRNFADVDEFSELVREVQTRPKRGRPANPQ
PSGPEHDLFGG

Sequences:

>Translated_171_residues
MKCPFCDDPNTQVTDTRENEDGDVVRRRRRCVKCDKRFTTYERVDLKMPHIVKRNGNRSEFDHSKLVGSMSLALRKRPVT
TEALEAAVDRIEAKLLSLGENEVASEKVGELVMKELKKLDKVAYIRFASVYRNFADVDEFSELVREVQTRPKRGRPANPQ
PSGPEHDLFGG
>Mature_171_residues
MKCPFCDDPNTQVTDTRENEDGDVVRRRRRCVKCDKRFTTYERVDLKMPHIVKRNGNRSEFDHSKLVGSMSLALRKRPVT
TEALEAAVDRIEAKLLSLGENEVASEKVGELVMKELKKLDKVAYIRFASVYRNFADVDEFSELVREVQTRPKRGRPANPQ
PSGPEHDLFGG

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=142, Percent_Identity=52.112676056338, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_AZOSB (A1K9B3)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934305.1
- STRING:   A1K9B3
- GeneID:   4608924
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2802
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A1K9B3
- ProtClustDB:   PRK00464
- BioCyc:   ASP62928:AZO2802-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 19581; Mature: 19581

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCDDPNTQVTDTRENEDGDVVRRRRRCVKCDKRFTTYERVDLKMPHIVKRNGNRSE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCH
FDHSKLVGSMSLALRKRPVTTEALEAAVDRIEAKLLSLGENEVASEKVGELVMKELKKLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRNFADVDEFSELVREVQTRPKRGRPANPQPSGPEHDLFGG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKCPFCDDPNTQVTDTRENEDGDVVRRRRRCVKCDKRFTTYERVDLKMPHIVKRNGNRSE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCH
FDHSKLVGSMSLALRKRPVTTEALEAAVDRIEAKLLSLGENEVASEKVGELVMKELKKLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRNFADVDEFSELVREVQTRPKRGRPANPQPSGPEHDLFGG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA