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The map label for this gene is glpA [H]

Identifier: 119899040

GI number: 119899040

Start: 3031885

End: 3033474

Strand: Reverse

Name: glpA [H]

Synonym: azo2750

Alternate gene names: 119899040

Gene position: 3033474-3031885 (Counterclockwise)

Preceding gene: 119899041

Following gene: 119899037

Centisome position: 69.32

GC content: 73.02

Gene sequence:

>1590_bases
ATGAGCGGGCCACCCGGGCAGTCCCGCGCCGCCTTGCTGGCGCGGCTGCGCGCAGACCCCGTCTGGGACGTGCTCGTGGT
CGGCGGCGGCGCAAGCGGCTTGGGGTGCGCGGTGGATGCGGCCGCGCGCGGCTACCAGGTTGCGCTGGTCGAGGCGCGCG
ATTTCGCCCAGGGAACGAGTTCGCGCTCCACCAAGCTCATTCACGGCGGCGTGCGTTATCTCGCCCAGGGAAGGCTGGGG
CTGGTGCGCGAGGCGCTGCATGAACGTGCGCGGCTGCTGGAGAACGCCCCGCATCTGGTGCGTCCGCTGCGCTTCGTCGT
TCCGGCACGGCGCTGGTCGGAGCTGGCGACCGTGGGCGCCGGTCTTGGCCTTTACGACCTGCTCGCCGGGCGCGGCGGCA
TCGGGCGCAGCCGTCTGCTCGGTGCGGCGGAAACCCGCGCCGCGCTGCCCGGCGTGAAAGCCGACGGGTTGTGCGGCGGC
GTGGCCTACTGGGACGCGCAGTTCGATGACGCCCGCCTCGCGCTCGCCTTGGCGCGCACCCTTGCCGATCTGGGCGGCGT
GCCGCTCAACCACTGTGCGCTCGAACGCCTGCTGATCGAGGACGGCGTGATCCGGGGCGCCGTGGTGCGCGACACGGAGC
GCGCGGAACCCTTTGCGCTGCGCGCGCGGGTGGTGATCAACGCCACCGGCGTGTGGAGCGACCAGGTGCGCCGGCTCGCC
AACCCCGCGGCGCCGGCCACGCTGCGTCCCAGCCAGGGCGTGCATCTGGTGGTGGATCGCGCCTTCCTGCCTGGCCGGCA
GGCGCTGCTGGTGCCGCGCACCGAGGATGGCCGCGTGCTGTTCATGATTCCCTGGCAGGACCGGCTGCTGCTCGGCACCA
CCGACACCGCGAGGGCCGACCTTCCGCTCGAACCAGAGGCGCTGCCCGGGGAGGTGGATTTCATCCTGTCGACCGCGGCA
CGCTATCTCGAACGCGCTCCCGGGCGTGCCGACGTGCTCAGCGTGTTCGCCGGCCTGCGCCCCTTGCTTGAAAGCGCCGC
CGCGCGCAACAGCGGCGAGCTGTCGCGCGAGCACGTCGTGGAGGTCTCTGCGCAGGGGCTGGTGAGCATGCTGGGCGGCA
AGTGGACGACGTACCGCAGCATGGCGGCAGACGCGGTGGATGCGGCGATCGAGTGGGCGGGTTTGCCGGCGCGGCCGTGC
GCTACCGCCAGCCTGCGTCTGCACGGGGCAGCGGCGCCGCGCGGGGATCGGCTGGATGCGTATGGAAGCGACCTGAGCGG
GCTCGAATCACTGCCGGGCGCGGGCCGGGTGCTGGTCGAAGGGCTGGACCTGACCGAAGCCGAGGTCCGCCATGCCGCCC
GTGCGGAGTGGGCGCGCGGCGTGGAGGACGTGCTCGCGCGGCGCCACCGCGCCTTGTTCCTGGATGCGACGCTGGCCGCG
TGCGCCGCGCCGGCGGTGGCGCAGATACTTGCCGCCGAACTGGGCCGGGATGAGGGCTGGGTGGCTGCGCAGACCGACGC
ATTTCACGCGTTGGCCAGCGCCTACGGCGCGTCCCTCAGCCGAGCTTGTGCTGCAGCACGTAGCGGGTGA

Upstream 100 bases:

>100_bases
AGATCGACCGCGTCTTCACGCCGGCATGGAGCGAGGACCAGCGTGGGGCAGTGCGCGCACGCTGGGCAGACGCAGTCGCG
CGTTCCCGGGCCTGGGCTGC

Downstream 100 bases:

>100_bases
TCTCGGCGTTTGACGCGAGGTCCAGCTTTTCGAGGATGCGGGCGCGGTAGGTGCTGATGGTCTTCACGCTGAGGTGGAAC
TGCTCGCCGATGCGGGTGAG

Product: putative glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSGPPGQSRAALLARLRADPVWDVLVVGGGASGLGCAVDAAARGYQVALVEARDFAQGTSSRSTKLIHGGVRYLAQGRLG
LVREALHERARLLENAPHLVRPLRFVVPARRWSELATVGAGLGLYDLLAGRGGIGRSRLLGAAETRAALPGVKADGLCGG
VAYWDAQFDDARLALALARTLADLGGVPLNHCALERLLIEDGVIRGAVVRDTERAEPFALRARVVINATGVWSDQVRRLA
NPAAPATLRPSQGVHLVVDRAFLPGRQALLVPRTEDGRVLFMIPWQDRLLLGTTDTARADLPLEPEALPGEVDFILSTAA
RYLERAPGRADVLSVFAGLRPLLESAAARNSGELSREHVVEVSAQGLVSMLGGKWTTYRSMAADAVDAAIEWAGLPARPC
ATASLRLHGAAAPRGDRLDAYGSDLSGLESLPGAGRVLVEGLDLTEAEVRHAARAEWARGVEDVLARRHRALFLDATLAA
CAAPAVAQILAAELGRDEGWVAAQTDAFHALASAYGASLSRACAAARSG

Sequences:

>Translated_529_residues
MSGPPGQSRAALLARLRADPVWDVLVVGGGASGLGCAVDAAARGYQVALVEARDFAQGTSSRSTKLIHGGVRYLAQGRLG
LVREALHERARLLENAPHLVRPLRFVVPARRWSELATVGAGLGLYDLLAGRGGIGRSRLLGAAETRAALPGVKADGLCGG
VAYWDAQFDDARLALALARTLADLGGVPLNHCALERLLIEDGVIRGAVVRDTERAEPFALRARVVINATGVWSDQVRRLA
NPAAPATLRPSQGVHLVVDRAFLPGRQALLVPRTEDGRVLFMIPWQDRLLLGTTDTARADLPLEPEALPGEVDFILSTAA
RYLERAPGRADVLSVFAGLRPLLESAAARNSGELSREHVVEVSAQGLVSMLGGKWTTYRSMAADAVDAAIEWAGLPARPC
ATASLRLHGAAAPRGDRLDAYGSDLSGLESLPGAGRVLVEGLDLTEAEVRHAARAEWARGVEDVLARRHRALFLDATLAA
CAAPAVAQILAAELGRDEGWVAAQTDAFHALASAYGASLSRACAAARSG
>Mature_528_residues
SGPPGQSRAALLARLRADPVWDVLVVGGGASGLGCAVDAAARGYQVALVEARDFAQGTSSRSTKLIHGGVRYLAQGRLGL
VREALHERARLLENAPHLVRPLRFVVPARRWSELATVGAGLGLYDLLAGRGGIGRSRLLGAAETRAALPGVKADGLCGGV
AYWDAQFDDARLALALARTLADLGGVPLNHCALERLLIEDGVIRGAVVRDTERAEPFALRARVVINATGVWSDQVRRLAN
PAAPATLRPSQGVHLVVDRAFLPGRQALLVPRTEDGRVLFMIPWQDRLLLGTTDTARADLPLEPEALPGEVDFILSTAAR
YLERAPGRADVLSVFAGLRPLLESAAARNSGELSREHVVEVSAQGLVSMLGGKWTTYRSMAADAVDAAIEWAGLPARPCA
TASLRLHGAAAPRGDRLDAYGSDLSGLESLPGAGRVLVEGLDLTEAEVRHAARAEWARGVEDVLARRHRALFLDATLAAC
AAPAVAQILAAELGRDEGWVAAQTDAFHALASAYGASLSRACAAARSG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=540, Percent_Identity=38.5185185185185, Blast_Score=341, Evalue=9e-94,
Organism=Homo sapiens, GI285002231, Length=540, Percent_Identity=38.5185185185185, Blast_Score=341, Evalue=9e-94,
Organism=Escherichia coli, GI2367226, Length=463, Percent_Identity=30.6695464362851, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1788574, Length=401, Percent_Identity=29.925187032419, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17509253, Length=539, Percent_Identity=36.5491651205937, Blast_Score=292, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI115534726, Length=529, Percent_Identity=33.2703213610586, Blast_Score=278, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6322036, Length=449, Percent_Identity=37.8619153674833, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI161077125, Length=567, Percent_Identity=37.7425044091711, Blast_Score=321, Evalue=9e-88,
Organism=Drosophila melanogaster, GI24653942, Length=567, Percent_Identity=37.7425044091711, Blast_Score=321, Evalue=9e-88,
Organism=Drosophila melanogaster, GI24653944, Length=567, Percent_Identity=37.7425044091711, Blast_Score=321, Evalue=9e-88,
Organism=Drosophila melanogaster, GI20130025, Length=567, Percent_Identity=37.7425044091711, Blast_Score=321, Evalue=9e-88,
Organism=Drosophila melanogaster, GI19921278, Length=530, Percent_Identity=32.8301886792453, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24586295, Length=552, Percent_Identity=32.2463768115942, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI45550977, Length=382, Percent_Identity=30.6282722513089, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55693; Mature: 55562

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPPGQSRAALLARLRADPVWDVLVVGGGASGLGCAVDAAARGYQVALVEARDFAQGTS
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEEEHHHHHCCCC
SRSTKLIHGGVRYLAQGRLGLVREALHERARLLENAPHLVRPLRFVVPARRWSELATVGA
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHC
GLGLYDLLAGRGGIGRSRLLGAAETRAALPGVKADGLCGGVAYWDAQFDDARLALALART
CCHHHHHHHCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHH
LADLGGVPLNHCALERLLIEDGVIRGAVVRDTERAEPFALRARVVINATGVWSDQVRRLA
HHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEEEEEECCCCHHHHHHHC
NPAAPATLRPSQGVHLVVDRAFLPGRQALLVPRTEDGRVLFMIPWQDRLLLGTTDTARAD
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCCC
LPLEPEALPGEVDFILSTAARYLERAPGRADVLSVFAGLRPLLESAAARNSGELSREHVV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EVSAQGLVSMLGGKWTTYRSMAADAVDAAIEWAGLPARPCATASLRLHGAAAPRGDRLDA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
YGSDLSGLESLPGAGRVLVEGLDLTEAEVRHAARAEWARGVEDVLARRHRALFLDATLAA
CCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEEEEHHHHHH
CAAPAVAQILAAELGRDEGWVAAQTDAFHALASAYGASLSRACAAARSG
HHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGPPGQSRAALLARLRADPVWDVLVVGGGASGLGCAVDAAARGYQVALVEARDFAQGTS
CCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEEEHHHHHCCCC
SRSTKLIHGGVRYLAQGRLGLVREALHERARLLENAPHLVRPLRFVVPARRWSELATVGA
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHC
GLGLYDLLAGRGGIGRSRLLGAAETRAALPGVKADGLCGGVAYWDAQFDDARLALALART
CCHHHHHHHCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHH
LADLGGVPLNHCALERLLIEDGVIRGAVVRDTERAEPFALRARVVINATGVWSDQVRRLA
HHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEEEEEECCCCHHHHHHHC
NPAAPATLRPSQGVHLVVDRAFLPGRQALLVPRTEDGRVLFMIPWQDRLLLGTTDTARAD
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCCC
LPLEPEALPGEVDFILSTAARYLERAPGRADVLSVFAGLRPLLESAAARNSGELSREHVV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EVSAQGLVSMLGGKWTTYRSMAADAVDAAIEWAGLPARPCATASLRLHGAAAPRGDRLDA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
YGSDLSGLESLPGAGRVLVEGLDLTEAEVRHAARAEWARGVEDVLARRHRALFLDATLAA
CCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEEEEHHHHHH
CAAPAVAQILAAELGRDEGWVAAQTDAFHALASAYGASLSRACAAARSG
HHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]