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The map label for this gene is vsrD2 [H]

Identifier: 119899039

GI number: 119899039

Start: 3031290

End: 3031919

Strand: Direct

Name: vsrD2 [H]

Synonym: azo2749

Alternate gene names: 119899039

Gene position: 3031290-3031919 (Clockwise)

Preceding gene: 119899038

Following gene: 119899042

Centisome position: 69.27

GC content: 65.87

Gene sequence:

>630_bases
ATGGTGAAAGTGCTCATTGCCGACGATCACGCCGTCGTGCGCGGCGGGCTGCGCCAGTTCCTGTCCTCTACCGAAGAGTT
CGACATCGTCGCCGAGGCCGCCAACGGCCAGACCGCGCTGGAACTGGTGCGCACCAGCGGGTGCGACGTCGTGCTGCTCG
ACATCACGCTGCCGGACCTGAACGGCCTGGAAGTGCTCAAACGCATCAAACGCAGCAAGCCCGACCTGCCGGTGCTGATC
TTCAGCATGTTCTCGGAAGACGAGTTTGCGTTGCCGGCGCTGAACGCGGGCGCCTCCGGCTATCTCAACAAGGACAGTCC
GCCGGCCCAGATCCTGGCCGCGCTGCACACCGTGGTGGCCGGTGCGCGCTACGTCAGCCCCTCGCTCGCCGAACGCCTGC
TGGCCGGCACGATGTCGCCCGGCAAGCGGCTGCCGCACGAGAACCTGTCGCCGCGCGAAATGGCGGTGCTGCTGCTATTG
AGCAAGGGCGTTCCGCTCACCCGCATCGGCGAGCAGTTCCACCTCAGCGTGAAGACCATCAGCACCTACCGCGCCCGCAT
CCTCGAAAAGCTGGACCTCGCGTCAAACGCCGAGATCACCCGCTACGTGCTGCAGCACAAGCTCGGCTGA

Upstream 100 bases:

>100_bases
GGCGCCTCACCCTGAGCGGCGCGCCGCAAACCGGCACCCGGCTCACGCTGACCATTCCGCTGGACGCGGGCGCCGCGCAC
AGCCCGGAGAAAACCCCATC

Downstream 100 bases:

>100_bases
GGGACGCGCCGTAGGCGCTGGCCAACGCGTGAAATGCGTCGGTCTGCGCAGCCACCCAGCCCTCATCCCGGCCCAGTTCG
GCGGCAAGTATCTGCGCCAC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MVKVLIADDHAVVRGGLRQFLSSTEEFDIVAEAANGQTALELVRTSGCDVVLLDITLPDLNGLEVLKRIKRSKPDLPVLI
FSMFSEDEFALPALNAGASGYLNKDSPPAQILAALHTVVAGARYVSPSLAERLLAGTMSPGKRLPHENLSPREMAVLLLL
SKGVPLTRIGEQFHLSVKTISTYRARILEKLDLASNAEITRYVLQHKLG

Sequences:

>Translated_209_residues
MVKVLIADDHAVVRGGLRQFLSSTEEFDIVAEAANGQTALELVRTSGCDVVLLDITLPDLNGLEVLKRIKRSKPDLPVLI
FSMFSEDEFALPALNAGASGYLNKDSPPAQILAALHTVVAGARYVSPSLAERLLAGTMSPGKRLPHENLSPREMAVLLLL
SKGVPLTRIGEQFHLSVKTISTYRARILEKLDLASNAEITRYVLQHKLG
>Mature_209_residues
MVKVLIADDHAVVRGGLRQFLSSTEEFDIVAEAANGQTALELVRTSGCDVVLLDITLPDLNGLEVLKRIKRSKPDLPVLI
FSMFSEDEFALPALNAGASGYLNKDSPPAQILAALHTVVAGARYVSPSLAERLLAGTMSPGKRLPHENLSPREMAVLLLL
SKGVPLTRIGEQFHLSVKTISTYRARILEKLDLASNAEITRYVLQHKLG

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=34.4497607655502, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=32.843137254902, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=32.3671497584541, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1788712, Length=205, Percent_Identity=28.2926829268293, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=26.3414634146341, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22706; Mature: 22706

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVLIADDHAVVRGGLRQFLSSTEEFDIVAEAANGQTALELVRTSGCDVVLLDITLPDL
CEEEEEECCHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHCCCCCEEEEEEECCCC
NGLEVLKRIKRSKPDLPVLIFSMFSEDEFALPALNAGASGYLNKDSPPAQILAALHTVVA
CHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GARYVSPSLAERLLAGTMSPGKRLPHENLSPREMAVLLLLSKGVPLTRIGEQFHLSVKTI
HHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHEEEHHHH
STYRARILEKLDLASNAEITRYVLQHKLG
HHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVKVLIADDHAVVRGGLRQFLSSTEEFDIVAEAANGQTALELVRTSGCDVVLLDITLPDL
CEEEEEECCHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHCCCCCEEEEEEECCCC
NGLEVLKRIKRSKPDLPVLIFSMFSEDEFALPALNAGASGYLNKDSPPAQILAALHTVVA
CHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GARYVSPSLAERLLAGTMSPGKRLPHENLSPREMAVLLLLSKGVPLTRIGEQFHLSVKTI
HHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHEEEHHHH
STYRARILEKLDLASNAEITRYVLQHKLG
HHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]