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The map label for this gene is mcpB [H]

Identifier: 119898838

GI number: 119898838

Start: 2815984

End: 2817636

Strand: Direct

Name: mcpB [H]

Synonym: azo2547

Alternate gene names: 119898838

Gene position: 2815984-2817636 (Clockwise)

Preceding gene: 119898837

Following gene: 119898841

Centisome position: 64.35

GC content: 68.66

Gene sequence:

>1653_bases
ATGAAGCACACAGGCACCGCCACGCGCGGCGGCAATCTATCCGTACGCACCCTGCTCTACCTCGCCATCGGCATGCAGAT
CGTGCTGGCACTGGTGATCGGACTACTCGGCGTGCGCGGCATGTATTCCACGCTGAACGGGCTGGACAACGTCTACACCG
CGCGCGTGATCCCGCTGCGCGACCTGAAGGTGATTTCCGACGAATACGCGGTGGCGGTGGTCAATGCCACCCAGAAGGTG
CGCGACGGCACCGTGACGCCGGAAGACGGCGCCGCCGCGATGGAAGGCGCGCAGAAGCTGATCGCGGAGAAGTGGAAGAC
CTACCGCAGCGGCCAGCTCTCGGCGCGCGAGCGCGAACTCGCCGACGCCGCCGAACCGCTGATGGCGAAGGGCAACGAGC
TGATCGCCACGCTGGTGGACCGGCTCAAGCTCGGCGCCCTGTCCGAGGTGCACGCCACCGCCGAACGCCTGCTCTACCCC
ACGATGGACCCGATCACCGCGGCGATCCGCGAGCTGATCGAGTTGCAGCTCGACCTCGCGCGGCAGGGCTACGAAGCCGA
ACAGAGCGGCTTCAACCAGGCGGTGCTGGTGATGCTGGCCTTCATCGTCGGCGCCGCCGCGCTGTCGGGCGTGGGCGGCT
TCGTGTTCGCGCGCAACTTCCTGATGCGCCCGCTGGACGACGCCCGCCGCTTCGCCAACGACATCGCCGCGGGCAATCTC
GGCACCAGCATCCAGATCCATCGCGATGACGAGATCGGCAGCCTCGCCGCCGCCCTGCAGAAGATGCAGCAGGAACTGCG
CAGCATGGTGCGGATGATCCAGGACAACGCCGAGCGCATCGCTGCCGCAAGCGAGAACCTGGCCGGCAACACCGGCGAAA
TCTCGCGCGCCACCGAGCAGCAGTCGAGCGCGGCGGAGGCGATCGCGGCGGCGATCGAGCAGATGACGACCTCGATCAAC
CATGTGTCGGCCTTCACCGCGGATGCGCGCGGCATCGCCACCGAATCCGGCAACACCTCGCGCGCCGGCGCCGAGGTGAT
CCAGCGCGTGGTGCATGACATCGAGCGCGTCGCGCAGTCGGTGGATCAATCCGCCGCGGCGATCCGCACGCTGGGCCAGC
GCTCCAAGGAGATCGCCTCGGTGGTCACGGTGATCAAGGAAGTGGCGGACCAGACCAACCTGCTCGCGCTCAACGCGGCA
ATCGAGGCCGCGCGCGCCGGCGAGCAGGGCCGCGGCTTCGCGGTGGTGGCGGACGAGGTGCGCAAGCTCGCCGAACGCAC
CGCCGCCTCCACCGAGGACATCGCGCGCATCGTCGGACTGATCACCTCCGGCACCGACTCCGCGGTGCGGGCGATGGACG
AACAGGTGGCCGGGGTGCAGGCCAGCGTCACACTGGCGGCCGAGGCGGGCGAAGCGATCGGACGCATCAAGTCCTCGTCG
GAACAGGTGGTGTCCACGGTCAGCGACGTCTCCGCCGCGCTTGCCGAGCAATCGACCACCAGTACCGAGATTGCCCGCGG
CATCGAGGACATCGCCCAGATGAGCGGCCGCAACAGCCAGTCCGCGCGTGAAGTGGCGGGCGCGACGCGCGAACTCGCCG
GGCTTTCGCAGGAACTGCGCAACACCGTGCAGCGCTTCCGCATCGCCGGCTGA

Upstream 100 bases:

>100_bases
CTGTGGTAAAAACCCGAGCGGCCGACGGCATCGCACGCTGCCGGACCCCATACAAAATCACAAAAGCCGCCGCCCTCCCG
GGCGGTTGGAGGAGAACGCG

Downstream 100 bases:

>100_bases
AACCGGCGGTCGCGCAAAAAGCAACGGCCCCCGCGGGCAACTCGCGGGGGCCGTTTCGTTTGCCGTGGCTCAGCGACCGA
TCAGGCGCAGGTCGAGCCGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MKHTGTATRGGNLSVRTLLYLAIGMQIVLALVIGLLGVRGMYSTLNGLDNVYTARVIPLRDLKVISDEYAVAVVNATQKV
RDGTVTPEDGAAAMEGAQKLIAEKWKTYRSGQLSARERELADAAEPLMAKGNELIATLVDRLKLGALSEVHATAERLLYP
TMDPITAAIRELIELQLDLARQGYEAEQSGFNQAVLVMLAFIVGAAALSGVGGFVFARNFLMRPLDDARRFANDIAAGNL
GTSIQIHRDDEIGSLAAALQKMQQELRSMVRMIQDNAERIAAASENLAGNTGEISRATEQQSSAAEAIAAAIEQMTTSIN
HVSAFTADARGIATESGNTSRAGAEVIQRVVHDIERVAQSVDQSAAAIRTLGQRSKEIASVVTVIKEVADQTNLLALNAA
IEAARAGEQGRGFAVVADEVRKLAERTAASTEDIARIVGLITSGTDSAVRAMDEQVAGVQASVTLAAEAGEAIGRIKSSS
EQVVSTVSDVSAALAEQSTTSTEIARGIEDIAQMSGRNSQSAREVAGATRELAGLSQELRNTVQRFRIAG

Sequences:

>Translated_550_residues
MKHTGTATRGGNLSVRTLLYLAIGMQIVLALVIGLLGVRGMYSTLNGLDNVYTARVIPLRDLKVISDEYAVAVVNATQKV
RDGTVTPEDGAAAMEGAQKLIAEKWKTYRSGQLSARERELADAAEPLMAKGNELIATLVDRLKLGALSEVHATAERLLYP
TMDPITAAIRELIELQLDLARQGYEAEQSGFNQAVLVMLAFIVGAAALSGVGGFVFARNFLMRPLDDARRFANDIAAGNL
GTSIQIHRDDEIGSLAAALQKMQQELRSMVRMIQDNAERIAAASENLAGNTGEISRATEQQSSAAEAIAAAIEQMTTSIN
HVSAFTADARGIATESGNTSRAGAEVIQRVVHDIERVAQSVDQSAAAIRTLGQRSKEIASVVTVIKEVADQTNLLALNAA
IEAARAGEQGRGFAVVADEVRKLAERTAASTEDIARIVGLITSGTDSAVRAMDEQVAGVQASVTLAAEAGEAIGRIKSSS
EQVVSTVSDVSAALAEQSTTSTEIARGIEDIAQMSGRNSQSAREVAGATRELAGLSQELRNTVQRFRIAG
>Mature_550_residues
MKHTGTATRGGNLSVRTLLYLAIGMQIVLALVIGLLGVRGMYSTLNGLDNVYTARVIPLRDLKVISDEYAVAVVNATQKV
RDGTVTPEDGAAAMEGAQKLIAEKWKTYRSGQLSARERELADAAEPLMAKGNELIATLVDRLKLGALSEVHATAERLLYP
TMDPITAAIRELIELQLDLARQGYEAEQSGFNQAVLVMLAFIVGAAALSGVGGFVFARNFLMRPLDDARRFANDIAAGNL
GTSIQIHRDDEIGSLAAALQKMQQELRSMVRMIQDNAERIAAASENLAGNTGEISRATEQQSSAAEAIAAAIEQMTTSIN
HVSAFTADARGIATESGNTSRAGAEVIQRVVHDIERVAQSVDQSAAAIRTLGQRSKEIASVVTVIKEVADQTNLLALNAA
IEAARAGEQGRGFAVVADEVRKLAERTAASTEDIARIVGLITSGTDSAVRAMDEQVAGVQASVTLAAEAGEAIGRIKSSS
EQVVSTVSDVSAALAEQSTTSTEIARGIEDIAQMSGRNSQSAREVAGATRELAGLSQELRNTVQRFRIAG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=33.8983050847458, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1788194, Length=362, Percent_Identity=31.4917127071823, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=31.2883435582822, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=31.9088319088319, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789453, Length=306, Percent_Identity=26.797385620915, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58153; Mature: 58153

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTGTATRGGNLSVRTLLYLAIGMQIVLALVIGLLGVRGMYSTLNGLDNVYTARVIPLR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHH
DLKVISDEYAVAVVNATQKVRDGTVTPEDGAAAMEGAQKLIAEKWKTYRSGQLSAREREL
HHHHHCCCHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ADAAEPLMAKGNELIATLVDRLKLGALSEVHATAERLLYPTMDPITAAIRELIELQLDLA
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RQGYEAEQSGFNQAVLVMLAFIVGAAALSGVGGFVFARNFLMRPLDDARRFANDIAAGNL
HCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GTSIQIHRDDEIGSLAAALQKMQQELRSMVRMIQDNAERIAAASENLAGNTGEISRATEQ
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QSSAAEAIAAAIEQMTTSINHVSAFTADARGIATESGNTSRAGAEVIQRVVHDIERVAQS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VDQSAAAIRTLGQRSKEIASVVTVIKEVADQTNLLALNAAIEAARAGEQGRGFAVVADEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEHHHHHH
RKLAERTAASTEDIARIVGLITSGTDSAVRAMDEQVAGVQASVTLAAEAGEAIGRIKSSS
HHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHCCH
EQVVSTVSDVSAALAEQSTTSTEIARGIEDIAQMSGRNSQSAREVAGATRELAGLSQELR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
NTVQRFRIAG
HHHHHHHCCC
>Mature Secondary Structure
MKHTGTATRGGNLSVRTLLYLAIGMQIVLALVIGLLGVRGMYSTLNGLDNVYTARVIPLR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHH
DLKVISDEYAVAVVNATQKVRDGTVTPEDGAAAMEGAQKLIAEKWKTYRSGQLSAREREL
HHHHHCCCHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ADAAEPLMAKGNELIATLVDRLKLGALSEVHATAERLLYPTMDPITAAIRELIELQLDLA
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RQGYEAEQSGFNQAVLVMLAFIVGAAALSGVGGFVFARNFLMRPLDDARRFANDIAAGNL
HCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GTSIQIHRDDEIGSLAAALQKMQQELRSMVRMIQDNAERIAAASENLAGNTGEISRATEQ
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QSSAAEAIAAAIEQMTTSINHVSAFTADARGIATESGNTSRAGAEVIQRVVHDIERVAQS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VDQSAAAIRTLGQRSKEIASVVTVIKEVADQTNLLALNAAIEAARAGEQGRGFAVVADEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEHHHHHH
RKLAERTAASTEDIARIVGLITSGTDSAVRAMDEQVAGVQASVTLAAEAGEAIGRIKSSS
HHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHCCH
EQVVSTVSDVSAALAEQSTTSTEIARGIEDIAQMSGRNSQSAREVAGATRELAGLSQELR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
NTVQRFRIAG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]