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The map label for this gene is blh [H]

Identifier: 119898821

GI number: 119898821

Start: 2797558

End: 2798433

Strand: Direct

Name: blh [H]

Synonym: azo2530

Alternate gene names: 119898821

Gene position: 2797558-2798433 (Clockwise)

Preceding gene: 119898820

Following gene: 119898823

Centisome position: 63.93

GC content: 70.89

Gene sequence:

>876_bases
ATGACGACCTCCGCGCCGCAGCCCGCCGACATCCGGTCCTTCTTCGACGACGAAACCTGCACCGTCACGCACGTGGTGGC
CTGCCCGCAGACGCGGCGCGCGGCCATCATCGACAGCGTGCTCGACTTCGACCCCAAGTCCGGGCGCACCCGCCACACGC
AGGCGGACCGCGTGATCGAGCACGTGCGCGCGGCCGGACTGACGGTGGAGTGGCTGCTGGAAACCCACGCCCACGCCGAC
CACCTCAGCGCCGCGCCCTACCTGCAGCAGGCGCTGGGCGGCCGCACCGCCATCGGCGAGCACATCCGCGAGGTGCAGGC
GGTGTTCAAGCGCATCTTCAACGCTCACGACCTCGGCACCGAGGGCCGCGAGTTCGACCGCCTGTTCGCCGACGGCGAGC
GCTTTCACATCGGCGAGCTCGAAGTGGAGGTGATGCACACCCCGGGCCACACGCCAGCCTGCATCAGCTACCGCGTGGGC
GACGACGTCTTCGTCGGCGACACCCTGTTCATGCCTGACTACGGCACCGCGCGCTGCGACTTTCCCGGCGGCGATGCGGC
CACGCTGTACCGTTCCATCCAGAAGCTGCTGGCGCTGCCGCCGCACACCCGGCTGCACCTGTGCCACGACTACCCGCCGG
ACGGTCGCGCGCCGGCCTGGGTCAGCACCGTGGCCGAACAGCGGGCAGGCAACATCCACGTGGGCGACGGCAACAGCGAG
GCCGCCTTCGTGGCGCTGCGCAACGCGCGCGACGCGACCCTGGCGATGCCGGTGCTGATACTGCCGGCGGTGCAGGTGAA
CGTGCGCGCCGGCCACCTGCCGCCGCCGGAGGACAACGGCGTGCGCTACCTCAAGCTGCCGCTCAACCTGCTGTAG

Upstream 100 bases:

>100_bases
TTGGTTCCCCTCCAGGCCGGAGGCCGAAACGCGGCGGCGGACGTGATATGTCCGAAATCAGCAGCTAGAATATAAGCACT
TCTTTATATTCCAGCTGACC

Downstream 100 bases:

>100_bases
GCTCAGCCGGCGGCCCGCACGAGCCAGTCGCGCAGCAAGGTGGCCGCGGCGGTGGCGCAGGCCGCGCCGTAGCGTTCGGT
GTCGGCCCGCAGCGCGGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTTSAPQPADIRSFFDDETCTVTHVVACPQTRRAAIIDSVLDFDPKSGRTRHTQADRVIEHVRAAGLTVEWLLETHAHAD
HLSAAPYLQQALGGRTAIGEHIREVQAVFKRIFNAHDLGTEGREFDRLFADGERFHIGELEVEVMHTPGHTPACISYRVG
DDVFVGDTLFMPDYGTARCDFPGGDAATLYRSIQKLLALPPHTRLHLCHDYPPDGRAPAWVSTVAEQRAGNIHVGDGNSE
AAFVALRNARDATLAMPVLILPAVQVNVRAGHLPPPEDNGVRYLKLPLNLL

Sequences:

>Translated_291_residues
MTTSAPQPADIRSFFDDETCTVTHVVACPQTRRAAIIDSVLDFDPKSGRTRHTQADRVIEHVRAAGLTVEWLLETHAHAD
HLSAAPYLQQALGGRTAIGEHIREVQAVFKRIFNAHDLGTEGREFDRLFADGERFHIGELEVEVMHTPGHTPACISYRVG
DDVFVGDTLFMPDYGTARCDFPGGDAATLYRSIQKLLALPPHTRLHLCHDYPPDGRAPAWVSTVAEQRAGNIHVGDGNSE
AAFVALRNARDATLAMPVLILPAVQVNVRAGHLPPPEDNGVRYLKLPLNLL
>Mature_290_residues
TTSAPQPADIRSFFDDETCTVTHVVACPQTRRAAIIDSVLDFDPKSGRTRHTQADRVIEHVRAAGLTVEWLLETHAHADH
LSAAPYLQQALGGRTAIGEHIREVQAVFKRIFNAHDLGTEGREFDRLFADGERFHIGELEVEVMHTPGHTPACISYRVGD
DVFVGDTLFMPDYGTARCDFPGGDAATLYRSIQKLLALPPHTRLHLCHDYPPDGRAPAWVSTVAEQRAGNIHVGDGNSEA
AFVALRNARDATLAMPVLILPAVQVNVRAGHLPPPEDNGVRYLKLPLNLL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=271, Percent_Identity=29.1512915129151, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1787158, Length=184, Percent_Identity=32.0652173913043, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=263, Percent_Identity=27.7566539923954, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221330176, Length=213, Percent_Identity=28.6384976525822, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31952; Mature: 31821

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSAPQPADIRSFFDDETCTVTHVVACPQTRRAAIIDSVLDFDPKSGRTRHTQADRVIE
CCCCCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
HVRAAGLTVEWLLETHAHADHLSAAPYLQQALGGRTAIGEHIREVQAVFKRIFNAHDLGT
HHHHHCCCHHHHHHHHCCHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHCCCC
EGREFDRLFADGERFHIGELEVEVMHTPGHTPACISYRVGDDVFVGDTLFMPDYGTARCD
CCHHHHHHHCCCCEEEECEEEEEEEECCCCCCEEEEEECCCCEEECCEEECCCCCCEECC
FPGGDAATLYRSIQKLLALPPHTRLHLCHDYPPDGRAPAWVSTVAEQRAGNIHVGDGNSE
CCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCCCCC
AAFVALRNARDATLAMPVLILPAVQVNVRAGHLPPPEDNGVRYLKLPLNLL
EEEEEECCCCCCHHHHHHHEECEEEEEEEECCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TTSAPQPADIRSFFDDETCTVTHVVACPQTRRAAIIDSVLDFDPKSGRTRHTQADRVIE
CCCCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
HVRAAGLTVEWLLETHAHADHLSAAPYLQQALGGRTAIGEHIREVQAVFKRIFNAHDLGT
HHHHHCCCHHHHHHHHCCHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHCCCC
EGREFDRLFADGERFHIGELEVEVMHTPGHTPACISYRVGDDVFVGDTLFMPDYGTARCD
CCHHHHHHHCCCCEEEECEEEEEEEECCCCCCEEEEEECCCCEEECCEEECCCCCCEECC
FPGGDAATLYRSIQKLLALPPHTRLHLCHDYPPDGRAPAWVSTVAEQRAGNIHVGDGNSE
CCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCCCCC
AAFVALRNARDATLAMPVLILPAVQVNVRAGHLPPPEDNGVRYLKLPLNLL
EEEEEECCCCCCHHHHHHHEECEEEEEEEECCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]