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The map label for this gene is panE1 [C]

Identifier: 119898762

GI number: 119898762

Start: 2728444

End: 2729406

Strand: Reverse

Name: panE1 [C]

Synonym: azo2471

Alternate gene names: 119898762

Gene position: 2729406-2728444 (Counterclockwise)

Preceding gene: 119898763

Following gene: 119898761

Centisome position: 62.37

GC content: 69.37

Gene sequence:

>963_bases
ATGACGAATCACGACACGGCGGCAGACACGGTGCCGCGCGTCCTGATGCTTGGGGCGGGGGCAATGGGTTCCCTGTTCGG
CGGCTTGCTGGCCGAGGTCGGCGTGCCAGTCACGCTGGTCGATATCAACGCGACGCACCTCGCCGCCATCCGCCGCGATG
GCCTGCGACTGGTGACCGATGGCGGCGAGCGGCGGGTGCGGCTCGATGCCTGTCGCCCGGACGACGTGCACGAGACGCCC
GACCTGATCGTGGTGTTCACGAAGGCCATGCACACCGATGCCGCGCTGGACGGCATACGGCGCTGGATCGGAGCGGAAAC
GCGCATCCTCAGCCTGCAGAACGGTCTGGGCAACGGCGAGCGGATCTGCGCGCATGCGGCGGCAGATCGTGTGGCGATCG
GGATGACCACCTGCCCGGCCGACCTGTGCGGCCCCGGCCATGTCGAATCGCACGGCCAGGGAAAAATCCGCTTCACCCGC
CTGGACGGCGGTCAGGACGACGCCCTCGAGCGCCTGGCAGCCCTGTTGCGTCGCGCGGGCCTCGACTGTGCGATCGATCC
GATGGTAAACACCGCGATCTGGGAAAAGGTCGCCTTCAACGCGGCCTTGAACAGCATCTGCACGGTGAGCGCCGGTCCGG
TCGACGCCATCGGCCGCACGCCGGGGGCGCAAGCCCTCGCGCTGGACATCGTGGATGAAGTCCTCGCGGTGGCGCGTGCC
GAGGGGCTTGCGGTCGATGCGGACCGGGTCCGCGCAAGCGTGCTGCATGCCATCGGTCATCATGTCGGCCACAAGCCGTC
GATGTTGCAGGACGTGCTTGCCGGGCGGCCCACCGAGATCGAGGCCATCAACGGGGCGGTCGTGGCACGGGCCGGGTTGC
GGGGCATCGCGACGCCGGCGACCCGAGCCTTGCTGGCCCTGGTCAGGCTCGTCGAGGCTGGTCGCAGTACGCCCTCGGCC
TGA

Upstream 100 bases:

>100_bases
CGCGCCAGGGGCACTGAGCGGTCCGGCGCACCGCCGGCCGCGGGCAGCCCACGGTCGGCGATGCGGCGGATGTTCCCCGC
GCAACGCTGTTGGAGAAAAC

Downstream 100 bases:

>100_bases
CCGGCCGAGATTCCCCCGCTTTTGAATGAAGAATGAATGGATATCGATGACTTGCGCCGGCAGGCGCGGCGCTTCCTGCC
CCGGTTCGTATTCGATTTTC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTNHDTAADTVPRVLMLGAGAMGSLFGGLLAEVGVPVTLVDINATHLAAIRRDGLRLVTDGGERRVRLDACRPDDVHETP
DLIVVFTKAMHTDAALDGIRRWIGAETRILSLQNGLGNGERICAHAAADRVAIGMTTCPADLCGPGHVESHGQGKIRFTR
LDGGQDDALERLAALLRRAGLDCAIDPMVNTAIWEKVAFNAALNSICTVSAGPVDAIGRTPGAQALALDIVDEVLAVARA
EGLAVDADRVRASVLHAIGHHVGHKPSMLQDVLAGRPTEIEAINGAVVARAGLRGIATPATRALLALVRLVEAGRSTPSA

Sequences:

>Translated_320_residues
MTNHDTAADTVPRVLMLGAGAMGSLFGGLLAEVGVPVTLVDINATHLAAIRRDGLRLVTDGGERRVRLDACRPDDVHETP
DLIVVFTKAMHTDAALDGIRRWIGAETRILSLQNGLGNGERICAHAAADRVAIGMTTCPADLCGPGHVESHGQGKIRFTR
LDGGQDDALERLAALLRRAGLDCAIDPMVNTAIWEKVAFNAALNSICTVSAGPVDAIGRTPGAQALALDIVDEVLAVARA
EGLAVDADRVRASVLHAIGHHVGHKPSMLQDVLAGRPTEIEAINGAVVARAGLRGIATPATRALLALVRLVEAGRSTPSA
>Mature_319_residues
TNHDTAADTVPRVLMLGAGAMGSLFGGLLAEVGVPVTLVDINATHLAAIRRDGLRLVTDGGERRVRLDACRPDDVHETPD
LIVVFTKAMHTDAALDGIRRWIGAETRILSLQNGLGNGERICAHAAADRVAIGMTTCPADLCGPGHVESHGQGKIRFTRL
DGGQDDALERLAALLRRAGLDCAIDPMVNTAIWEKVAFNAALNSICTVSAGPVDAIGRTPGAQALALDIVDEVLAVARAE
GLAVDADRVRASVLHAIGHHVGHKPSMLQDVLAGRPTEIEAINGAVVARAGLRGIATPATRALLALVRLVEAGRSTPSA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=309, Percent_Identity=28.1553398058252, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33354; Mature: 33223

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHDTAADTVPRVLMLGAGAMGSLFGGLLAEVGVPVTLVDINATHLAAIRRDGLRLVTD
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEC
GGERRVRLDACRPDDVHETPDLIVVFTKAMHTDAALDGIRRWIGAETRILSLQNGLGNGE
CCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
RICAHAAADRVAIGMTTCPADLCGPGHVESHGQGKIRFTRLDGGQDDALERLAALLRRAG
HHHHHHHHCCEEEEEEECCHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
LDCAIDPMVNTAIWEKVAFNAALNSICTVSAGPVDAIGRTPGAQALALDIVDEVLAVARA
CCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
EGLAVDADRVRASVLHAIGHHVGHKPSMLQDVLAGRPTEIEAINGAVVARAGLRGIATPA
CCCEECHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHCCHHHHHCCCCCCCCHH
TRALLALVRLVEAGRSTPSA
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNHDTAADTVPRVLMLGAGAMGSLFGGLLAEVGVPVTLVDINATHLAAIRRDGLRLVTD
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEC
GGERRVRLDACRPDDVHETPDLIVVFTKAMHTDAALDGIRRWIGAETRILSLQNGLGNGE
CCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
RICAHAAADRVAIGMTTCPADLCGPGHVESHGQGKIRFTRLDGGQDDALERLAALLRRAG
HHHHHHHHCCEEEEEEECCHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
LDCAIDPMVNTAIWEKVAFNAALNSICTVSAGPVDAIGRTPGAQALALDIVDEVLAVARA
CCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
EGLAVDADRVRASVLHAIGHHVGHKPSMLQDVLAGRPTEIEAINGAVVARAGLRGIATPA
CCCEECHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHCCHHHHHCCCCCCCCHH
TRALLALVRLVEAGRSTPSA
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]