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The map label for this gene is arsA [H]

Identifier: 119898647

GI number: 119898647

Start: 2594802

End: 2596550

Strand: Direct

Name: arsA [H]

Synonym: azo2356

Alternate gene names: 119898647

Gene position: 2594802-2596550 (Clockwise)

Preceding gene: 119898646

Following gene: 119898651

Centisome position: 59.3

GC content: 72.84

Gene sequence:

>1749_bases
ATGACACTGCCGCGCGCCAGCACCCGCTACCTGTTCTTCACCGGCAAGGGCGGGGTCGGCAAGACCTCGCTTTCGTGCGC
CACCGGCCTTGCACTCGCCGAGGCCGGCCGGCGCGTGCTGATCGTCAGCACCGACCCGGCCTCCAACCTGGACGAGGTGC
TCGGCACCGAGCTCGGCCAGACGCCCACCGCCATCGCTGGCGCGCCCGGGCTGTACGCGCTCAACATCGACCCTGAAGCG
GCTGCCGCGGCCTACCGCGAGCGCATGGTAGGGCCCTACCGCGGCATCCTGCCGGCGGCGGCGATCCAGAGCATGGAAGA
ACAGTTCTCCGGCGCCTGCACCGTGGAGATCGCCGCCTTCGACGAGTTCTCCAAGCTGCTCGGCGAGCCCGCCGCCACCG
CCGGTTTCGACCATGTGATCTTCGACACTGCGCCCACCGGCCACACCTTGCGCCTGCTGACGCTGCCGAGCGCGTGGAGC
GAGTTCATCTCGTCGTCCACCGGCGGCGCCTCCTGCCTCGGTCCGCTGGCCGGGCTGCAACAGCAGAAGGCGCTCTACGC
CGCCACCGTGGAACGCCTCGCCGACCCGCAGGCCACCACCGTGATCCTGGTGAGCCGCGCCGAAACTGCCGCGCTGCGCG
AGGCCGAGCGCACCCGCGGCGAACTGGCGGAACTGGGCATCCGCAATCAGGTGCTGGCGATCAACGGCCTGTTCGCCGAT
ACGGACACCGACGACGCGATCGCCGCCGCGATGTCGCAGCGCGGCGCCAAGGCGCTCGCCGCGATGCCGGCCGCGCTGCG
CGAACTGCCCGCCACCACCATCCCCTTCCTGCCCGCGGGCACGGTGGGCCTGGACGCGCTGCGGGTGATGGCGCAGCCGG
AGCGCATGGCGGCGCCCACCACCGCCGAGCCGGCCGCGCTGCCGCAGGTCGCGCTCGGCCTGGGCGCGATGGTCGATGAC
ATCGCCCGCAGCGGCCACGGCGTGGTGATGACGATGGGCAAAGGCGGCGTCGGCAAAACCACCGCGGCGGCCGCCATCGC
GCTGGCCCTGGCGCAGCGCGGCCACAAGGTCACGCTCTCCACCACCGACCCCGCCGCCCACCTGTCCACCACACTGGCCG
AGGCGGTGCCCGGCCTCAGCCTTGCCCGCATCGACCCCGCGCGCGAGGTTGCCGACTACAGCGCCGAGGTGATGGCGCGC
GCCGGCCAGGGGCTGGATGCCGCCGCGCGGGCGATGCTCGAGGAAGACCTGCGCTCGCCCTGCACCGAGGAGATCGCGGT
GTTCCGCGCCTTCGCGCGCACGGTGGACCAGGGCAAGGACGGCTTCGTGGTGCTCGATACCGCGCCCACCGGCCACACCA
TCCTGCTGCTCGATGCCGCCGAGGCCTACCACCGCGAGGTGAGCCGCACCCAGGGCGAGATGCCGGAGGCGGTACGCCAG
CTGCTGCCGCGCCTGCGCGACCCGGCATTCACCCACGTGCTGATCGTCACCCTGCCCGAAGCCACGCCGGTGCACGAGGC
CGAGCGCCTGCAGGCCGACCTTGCCCGCGCGGGCATCACGCCCTACGGCTGGGTGGTCAACCAGTCCCTGCTCGCCAGCG
GCACGCACCATCCCCTGCTGGCGCAGCGCGCCCACCACGAGCTTCCGTTCATCCGCCGGGTCAGCCAGGACCTCGCCGCG
CGCTTCGCACTGCTGCCCTGGCTGGCCGAGGCGCCAGTGGGCGTGGAAGGTCTGCGCCAGGTGCTGTAG

Upstream 100 bases:

>100_bases
AAGCTGGGCATCACCCTCACCCGCGAGGAAAAGCCGCACATCAAGATCGGCAGCGCCTGCTGCGATCCCAAGTCCGGCTG
TTGCTGAGCGGAGCGCCGCG

Downstream 100 bases:

>100_bases
CGCCGGGCGGGCGCGTCCGCCGCCGCCACGCCCCCGCCCGGATCAAGCCGCGAGCGGGGGCGGCACGAATCCCCCGAGGG
CGTTTTCCAGCCGGCGGCCG

Product: arsenite-transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MTLPRASTRYLFFTGKGGVGKTSLSCATGLALAEAGRRVLIVSTDPASNLDEVLGTELGQTPTAIAGAPGLYALNIDPEA
AAAAYRERMVGPYRGILPAAAIQSMEEQFSGACTVEIAAFDEFSKLLGEPAATAGFDHVIFDTAPTGHTLRLLTLPSAWS
EFISSSTGGASCLGPLAGLQQQKALYAATVERLADPQATTVILVSRAETAALREAERTRGELAELGIRNQVLAINGLFAD
TDTDDAIAAAMSQRGAKALAAMPAALRELPATTIPFLPAGTVGLDALRVMAQPERMAAPTTAEPAALPQVALGLGAMVDD
IARSGHGVVMTMGKGGVGKTTAAAAIALALAQRGHKVTLSTTDPAAHLSTTLAEAVPGLSLARIDPAREVADYSAEVMAR
AGQGLDAAARAMLEEDLRSPCTEEIAVFRAFARTVDQGKDGFVVLDTAPTGHTILLLDAAEAYHREVSRTQGEMPEAVRQ
LLPRLRDPAFTHVLIVTLPEATPVHEAERLQADLARAGITPYGWVVNQSLLASGTHHPLLAQRAHHELPFIRRVSQDLAA
RFALLPWLAEAPVGVEGLRQVL

Sequences:

>Translated_582_residues
MTLPRASTRYLFFTGKGGVGKTSLSCATGLALAEAGRRVLIVSTDPASNLDEVLGTELGQTPTAIAGAPGLYALNIDPEA
AAAAYRERMVGPYRGILPAAAIQSMEEQFSGACTVEIAAFDEFSKLLGEPAATAGFDHVIFDTAPTGHTLRLLTLPSAWS
EFISSSTGGASCLGPLAGLQQQKALYAATVERLADPQATTVILVSRAETAALREAERTRGELAELGIRNQVLAINGLFAD
TDTDDAIAAAMSQRGAKALAAMPAALRELPATTIPFLPAGTVGLDALRVMAQPERMAAPTTAEPAALPQVALGLGAMVDD
IARSGHGVVMTMGKGGVGKTTAAAAIALALAQRGHKVTLSTTDPAAHLSTTLAEAVPGLSLARIDPAREVADYSAEVMAR
AGQGLDAAARAMLEEDLRSPCTEEIAVFRAFARTVDQGKDGFVVLDTAPTGHTILLLDAAEAYHREVSRTQGEMPEAVRQ
LLPRLRDPAFTHVLIVTLPEATPVHEAERLQADLARAGITPYGWVVNQSLLASGTHHPLLAQRAHHELPFIRRVSQDLAA
RFALLPWLAEAPVGVEGLRQVL
>Mature_581_residues
TLPRASTRYLFFTGKGGVGKTSLSCATGLALAEAGRRVLIVSTDPASNLDEVLGTELGQTPTAIAGAPGLYALNIDPEAA
AAAYRERMVGPYRGILPAAAIQSMEEQFSGACTVEIAAFDEFSKLLGEPAATAGFDHVIFDTAPTGHTLRLLTLPSAWSE
FISSSTGGASCLGPLAGLQQQKALYAATVERLADPQATTVILVSRAETAALREAERTRGELAELGIRNQVLAINGLFADT
DTDDAIAAAMSQRGAKALAAMPAALRELPATTIPFLPAGTVGLDALRVMAQPERMAAPTTAEPAALPQVALGLGAMVDDI
ARSGHGVVMTMGKGGVGKTTAAAAIALALAQRGHKVTLSTTDPAAHLSTTLAEAVPGLSLARIDPAREVADYSAEVMARA
GQGLDAAARAMLEEDLRSPCTEEIAVFRAFARTVDQGKDGFVVLDTAPTGHTILLLDAAEAYHREVSRTQGEMPEAVRQL
LPRLRDPAFTHVLIVTLPEATPVHEAERLQADLARAGITPYGWVVNQSLLASGTHHPLLAQRAHHELPFIRRVSQDLAAR
FALLPWLAEAPVGVEGLRQVL

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=307, Percent_Identity=29.6416938110749, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17557003, Length=334, Percent_Identity=28.4431137724551, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320103, Length=301, Percent_Identity=26.9102990033223, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24586297, Length=313, Percent_Identity=27.4760383386581, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003593
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 60939; Mature: 60808

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPRASTRYLFFTGKGGVGKTSLSCATGLALAEAGRRVLIVSTDPASNLDEVLGTELGQ
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCC
TPTAIAGAPGLYALNIDPEAAAAAYRERMVGPYRGILPAAAIQSMEEQFSGACTVEIAAF
CCCHHCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECH
DEFSKLLGEPAATAGFDHVIFDTAPTGHTLRLLTLPSAWSEFISSSTGGASCLGPLAGLQ
HHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHH
QQKALYAATVERLADPQATTVILVSRAETAALREAERTRGELAELGIRNQVLAINGLFAD
HHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
TDTDDAIAAAMSQRGAKALAAMPAALRELPATTIPFLPAGTVGLDALRVMAQPERMAAPT
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCC
TAEPAALPQVALGLGAMVDDIARSGHGVVMTMGKGGVGKTTAAAAIALALAQRGHKVTLS
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEE
TTDPAAHLSTTLAEAVPGLSLARIDPAREVADYSAEVMARAGQGLDAAARAMLEEDLRSP
CCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
CTEEIAVFRAFARTVDQGKDGFVVLDTAPTGHTILLLDAAEAYHREVSRTQGEMPEAVRQ
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHH
LLPRLRDPAFTHVLIVTLPEATPVHEAERLQADLARAGITPYGWVVNQSLLASGTHHPLL
HHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHH
AQRAHHELPFIRRVSQDLAARFALLPWLAEAPVGVEGLRQVL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
>Mature Secondary Structure 
TLPRASTRYLFFTGKGGVGKTSLSCATGLALAEAGRRVLIVSTDPASNLDEVLGTELGQ
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCC
TPTAIAGAPGLYALNIDPEAAAAAYRERMVGPYRGILPAAAIQSMEEQFSGACTVEIAAF
CCCHHCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECH
DEFSKLLGEPAATAGFDHVIFDTAPTGHTLRLLTLPSAWSEFISSSTGGASCLGPLAGLQ
HHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHH
QQKALYAATVERLADPQATTVILVSRAETAALREAERTRGELAELGIRNQVLAINGLFAD
HHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
TDTDDAIAAAMSQRGAKALAAMPAALRELPATTIPFLPAGTVGLDALRVMAQPERMAAPT
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCC
TAEPAALPQVALGLGAMVDDIARSGHGVVMTMGKGGVGKTTAAAAIALALAQRGHKVTLS
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEE
TTDPAAHLSTTLAEAVPGLSLARIDPAREVADYSAEVMARAGQGLDAAARAMLEEDLRSP
CCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
CTEEIAVFRAFARTVDQGKDGFVVLDTAPTGHTILLLDAAEAYHREVSRTQGEMPEAVRQ
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHH
LLPRLRDPAFTHVLIVTLPEATPVHEAERLQADLARAGITPYGWVVNQSLLASGTHHPLL
HHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHH
AQRAHHELPFIRRVSQDLAARFALLPWLAEAPVGVEGLRQVL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9464374 [H]