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The map label for this gene is gumM [H]

Identifier: 119898524

GI number: 119898524

Start: 2447180

End: 2447938

Strand: Reverse

Name: gumM [H]

Synonym: azo2233

Alternate gene names: 119898524

Gene position: 2447938-2447180 (Counterclockwise)

Preceding gene: 119898525

Following gene: 119898523

Centisome position: 55.94

GC content: 70.09

Gene sequence:

>759_bases
ATGGAAAACACGCTCTATCTCGGCGGATTCCGCATCCGCAGCGTCACCGGCGACGACTTCGCGGACGAACTCCTGCGCCA
CTGCGAGGCGCGGGAGAGACGCCGCGTGGTGTTCGCCAACACCAACTTCATCGTGCAGTGCAGGGGGCTGCGGCGGCGCC
TGGCGCGCGGCTCGGTATGCGTGGTCAACGACGGCATCGGCGTAGACCTCGCCGCCTTGCTGGTGCATGGCCGGCGCTTC
GCCGACAACCTTGCCGGCAGCGACTTCATTCCCAAGCTGTGCGAGCGCAGCCCGCGCCCCTTGCGTTTCTTCCTGCTCGG
CAGCCGGCCGGGCGTGGCGATGCGCGCCGGGCAGCGGCTGGTGGAGGAGTACGGCCAGGAGGTGGTCGGCTGTTGCGACG
GCTACGACGGCTTTGCCGCGCTGCGCGAGAGCGGCCAGCTTGCCGAACGCATCAACGAGAGCGGCGCCGACGTGGTGCTG
GTGGCCTTCGGCAATCCGATGCAGGAGCAATGGATGCTGGACCACGACGAGGCGATCGAGGCGCCGCTGATGTTCGGCGT
GGGCGCGCTGCTCGACTTTCTCGCCGGCGAGGCCAAACGGGCACCGGAGTGGGTGCGGCGCGCCCGGCTCGAATGGCTGT
ACCGCCTGGCGCGCGAGCCGCGCCGTCTGCTGCGCCGCTACACGCTGGACATTGTCACCTTTCTGTCGATCTGCCTGCTG
GCGGGCCGGGGCGCGGCGCGCGTCGGCCAGGCGCGCTGA

Upstream 100 bases:

>100_bases
CTGGTCGCCCGCCTCAGTCGCGGCAGCTACAACGCCTTCGGCGAGCTGCAGCGGCTGCGGCGCGCGGCCGGACGTTGATT
TTCATTTCGGCAGACCGGTC

Downstream 100 bases:

>100_bases
TCGGCCGCGCCACCGTTTTCGCTTAACAGGGAGCCCAAGCAATGAAAATCACCGTCATCGGGACCGGCTATGTGGGCCTG
GTTTCCGGCGCCTGCCTGGC

Product: putative glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MENTLYLGGFRIRSVTGDDFADELLRHCEARERRRVVFANTNFIVQCRGLRRRLARGSVCVVNDGIGVDLAALLVHGRRF
ADNLAGSDFIPKLCERSPRPLRFFLLGSRPGVAMRAGQRLVEEYGQEVVGCCDGYDGFAALRESGQLAERINESGADVVL
VAFGNPMQEQWMLDHDEAIEAPLMFGVGALLDFLAGEAKRAPEWVRRARLEWLYRLAREPRRLLRRYTLDIVTFLSICLL
AGRGAARVGQAR

Sequences:

>Translated_252_residues
MENTLYLGGFRIRSVTGDDFADELLRHCEARERRRVVFANTNFIVQCRGLRRRLARGSVCVVNDGIGVDLAALLVHGRRF
ADNLAGSDFIPKLCERSPRPLRFFLLGSRPGVAMRAGQRLVEEYGQEVVGCCDGYDGFAALRESGQLAERINESGADVVL
VAFGNPMQEQWMLDHDEAIEAPLMFGVGALLDFLAGEAKRAPEWVRRARLEWLYRLAREPRRLLRRYTLDIVTFLSICLL
AGRGAARVGQAR
>Mature_252_residues
MENTLYLGGFRIRSVTGDDFADELLRHCEARERRRVVFANTNFIVQCRGLRRRLARGSVCVVNDGIGVDLAALLVHGRRF
ADNLAGSDFIPKLCERSPRPLRFFLLGSRPGVAMRAGQRLVEEYGQEVVGCCDGYDGFAALRESGQLAERINESGADVVL
VAFGNPMQEQWMLDHDEAIEAPLMFGVGALLDFLAGEAKRAPEWVRRARLEWLYRLAREPRRLLRRYTLDIVTFLSICLL
AGRGAARVGQAR

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=165, Percent_Identity=35.1515151515151, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 28283; Mature: 28283

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTLYLGGFRIRSVTGDDFADELLRHCEARERRRVVFANTNFIVQCRGLRRRLARGSVC
CCCCEEECCEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCEEEEEHHHHHHHHCCCEE
VVNDGIGVDLAALLVHGRRFADNLAGSDFIPKLCERSPRPLRFFLLGSRPGVAMRAGQRL
EEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHH
VEEYGQEVVGCCDGYDGFAALRESGQLAERINESGADVVLVAFGNPMQEQWMLDHDEAIE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCCCCHHHHH
APLMFGVGALLDFLAGEAKRAPEWVRRARLEWLYRLAREPRRLLRRYTLDIVTFLSICLL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRGAARVGQAR
HCCCCCCCCCCC
>Mature Secondary Structure
MENTLYLGGFRIRSVTGDDFADELLRHCEARERRRVVFANTNFIVQCRGLRRRLARGSVC
CCCCEEECCEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCEEEEEHHHHHHHHCCCEE
VVNDGIGVDLAALLVHGRRFADNLAGSDFIPKLCERSPRPLRFFLLGSRPGVAMRAGQRL
EEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHH
VEEYGQEVVGCCDGYDGFAALRESGQLAERINESGADVVLVAFGNPMQEQWMLDHDEAIE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCCCCHHHHH
APLMFGVGALLDFLAGEAKRAPEWVRRARLEWLYRLAREPRRLLRRYTLDIVTFLSICLL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRGAARVGQAR
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11882717 [H]