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The map label for this gene is udgH [H]

Identifier: 119898523

GI number: 119898523

Start: 2445816

End: 2447138

Strand: Reverse

Name: udgH [H]

Synonym: azo2232

Alternate gene names: 119898523

Gene position: 2447138-2445816 (Counterclockwise)

Preceding gene: 119898524

Following gene: 119898522

Centisome position: 55.92

GC content: 66.89

Gene sequence:

>1323_bases
ATGAAAATCACCGTCATCGGGACCGGCTATGTGGGCCTGGTTTCCGGCGCCTGCCTGGCGGATGTCGGCAACGAAGTGCT
CTGCCTCGACGTCGATCCGGCCAAGATCCGCATCCTGGAAGAAGGGGCGATTCCGATCCACGAACCCGGCCTGCTCGAGA
TCGTCCGCCGCAATGTGGAGGCGGGACGGCTGAGCTTCACCACCGATCCGGTGAAAGCCGCGCAGCACGGCCTGGTGCAG
TTCATCGCGGTCGGCACGCCGCCGGACGAGGACGGCTCGGCCGACCTGCAGTACGTGCTCGCCGCCGCGCGCAACATCGG
CCGTCATCTGGATGGCTACCGGGTGGTGGTGGACAAGTCCACCGTGCCGGTGGGCACCGCGGACAAGGTGCGCGCGGCAA
TCGCCGACGAACTGGCCGCGCGCGGCTCCAGCGAGGCCTTCAGCGTCGTCTCCAATCCGGAGTTCCTCAAGGAAGGCGCC
GCAGTGGACGACTTCATGCGGCCGGACCGCATCGTCATCGGCGCCGACGACGAACGCGCGATCGAGCTGATGCGCCAGCT
CTACGCCCCGTTCCAGCGCAAGCACGACAAGCTGGTGTTCATGGATGTACGCAGCGCTGAGCTGACCAAGTACGCCGCCA
ATGCGATGCTCGCCACCCGCATCAGCTTCATGAACGAACTGGCCAACCTCGCCGAAAGCCTGGGGGCGGACATCGAGCTT
GTCCGCCAGGGCATCGGCTCCGATCCCCGCATCGGCTGGCACTTCTTGTACGCGGGCTGCGGCTACGGCGGCTCGTGCTT
TCCGAAGGATGTGAAGGCGCTGATCCGGACCGCCGCCGAACAGGGCACCGCGTTGCGGGTGCTGACTGCGGTGGAAGAGG
CCAACGAGGTGCAGAAGCACGTGCTGATCGACAAGATCGTGCGTCGTTTCGGCACCGATCTTTCCGGCCGGCGCTTCGCG
CTGTGGGGGCTGGCTTTCAAGCCCGATACCGACGACATGCGCGAGGCGCCCAGCCGGGTGGTGGTGGAGGAACTGCTGGC
GCGCGGCGCCAGTGTCACCGCTTACGACCCCGTGGCGATGGGCGAGGCCGAACGCATCTTCGGCGACGAGCCGCGGATCA
GTTACGCCGGGCGGCCCAAGAGTGCGCTGGAAGGCGCCGATGCGCTGGTGATCCTGACCGAGTGGAAGGAATTCCGCAGT
CCGGACTTCGAAGCCATCCGCAGCCGGCTGCGCACGCCGGTGGTGTTCGACGGCCGCAACATCTACGAGCCTTCGGTGCT
GCGCGCCGCAGGCATCGAATACCACGGCATCGGCCGCCCGTGA

Upstream 100 bases:

>100_bases
TTCTGTCGATCTGCCTGCTGGCGGGCCGGGGCGCGGCGCGCGTCGGCCAGGCGCGCTGATCGGCCGCGCCACCGTTTTCG
CTTAACAGGGAGCCCAAGCA

Downstream 100 bases:

>100_bases
TCATCGCCGCGACAACGACAGGAGAGACTGCATGGCGAAGGGAATGATACTGGCGGCGGGGCAGGGCACCCGCGTACGGC
CGCTGACCAAGTACCTGCCC

Product: putative UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKITVIGTGYVGLVSGACLADVGNEVLCLDVDPAKIRILEEGAIPIHEPGLLEIVRRNVEAGRLSFTTDPVKAAQHGLVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHLDGYRVVVDKSTVPVGTADKVRAAIADELAARGSSEAFSVVSNPEFLKEGA
AVDDFMRPDRIVIGADDERAIELMRQLYAPFQRKHDKLVFMDVRSAELTKYAANAMLATRISFMNELANLAESLGADIEL
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALIRTAAEQGTALRVLTAVEEANEVQKHVLIDKIVRRFGTDLSGRRFA
LWGLAFKPDTDDMREAPSRVVVEELLARGASVTAYDPVAMGEAERIFGDEPRISYAGRPKSALEGADALVILTEWKEFRS
PDFEAIRSRLRTPVVFDGRNIYEPSVLRAAGIEYHGIGRP

Sequences:

>Translated_440_residues
MKITVIGTGYVGLVSGACLADVGNEVLCLDVDPAKIRILEEGAIPIHEPGLLEIVRRNVEAGRLSFTTDPVKAAQHGLVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHLDGYRVVVDKSTVPVGTADKVRAAIADELAARGSSEAFSVVSNPEFLKEGA
AVDDFMRPDRIVIGADDERAIELMRQLYAPFQRKHDKLVFMDVRSAELTKYAANAMLATRISFMNELANLAESLGADIEL
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALIRTAAEQGTALRVLTAVEEANEVQKHVLIDKIVRRFGTDLSGRRFA
LWGLAFKPDTDDMREAPSRVVVEELLARGASVTAYDPVAMGEAERIFGDEPRISYAGRPKSALEGADALVILTEWKEFRS
PDFEAIRSRLRTPVVFDGRNIYEPSVLRAAGIEYHGIGRP
>Mature_440_residues
MKITVIGTGYVGLVSGACLADVGNEVLCLDVDPAKIRILEEGAIPIHEPGLLEIVRRNVEAGRLSFTTDPVKAAQHGLVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHLDGYRVVVDKSTVPVGTADKVRAAIADELAARGSSEAFSVVSNPEFLKEGA
AVDDFMRPDRIVIGADDERAIELMRQLYAPFQRKHDKLVFMDVRSAELTKYAANAMLATRISFMNELANLAESLGADIEL
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALIRTAAEQGTALRVLTAVEEANEVQKHVLIDKIVRRFGTDLSGRRFA
LWGLAFKPDTDDMREAPSRVVVEELLARGASVTAYDPVAMGEAERIFGDEPRISYAGRPKSALEGADALVILTEWKEFRS
PDFEAIRSRLRTPVVFDGRNIYEPSVLRAAGIEYHGIGRP

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=464, Percent_Identity=35.3448275862069, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=36.0655737704918, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI296040443, Length=311, Percent_Identity=35.6913183279743, Blast_Score=180, Evalue=2e-45,
Organism=Escherichia coli, GI1788340, Length=361, Percent_Identity=30.4709141274238, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI48994968, Length=446, Percent_Identity=28.0269058295964, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=462, Percent_Identity=33.7662337662338, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI17136908, Length=468, Percent_Identity=35.8974358974359, Blast_Score=247, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47920; Mature: 47920

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVIGTGYVGLVSGACLADVGNEVLCLDVDPAKIRILEEGAIPIHEPGLLEIVRRNVE
CEEEEEECCHHHHHCCHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHCCC
AGRLSFTTDPVKAAQHGLVQFIAVGTPPDEDGSADLQYVLAAARNIGRHLDGYRVVVDKS
CCEEEECCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTADKVRAAIADELAARGSSEAFSVVSNPEFLKEGAAVDDFMRPDRIVIGADDERA
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
IELMRQLYAPFQRKHDKLVFMDVRSAELTKYAANAMLATRISFMNELANLAESLGADIEL
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALIRTAAEQGTALRVLTAVEEANEVQKH
HHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHH
VLIDKIVRRFGTDLSGRRFALWGLAFKPDTDDMREAPSRVVVEELLARGASVTAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHC
GEAERIFGDEPRISYAGRPKSALEGADALVILTEWKEFRSPDFEAIRSRLRTPVVFDGRN
CCHHHHCCCCCCEEECCCCHHHHCCCCEEEEEECHHHHCCCCHHHHHHHCCCCEEECCCC
IYEPSVLRAAGIEYHGIGRP
CCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKITVIGTGYVGLVSGACLADVGNEVLCLDVDPAKIRILEEGAIPIHEPGLLEIVRRNVE
CEEEEEECCHHHHHCCHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHCCC
AGRLSFTTDPVKAAQHGLVQFIAVGTPPDEDGSADLQYVLAAARNIGRHLDGYRVVVDKS
CCEEEECCCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTADKVRAAIADELAARGSSEAFSVVSNPEFLKEGAAVDDFMRPDRIVIGADDERA
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
IELMRQLYAPFQRKHDKLVFMDVRSAELTKYAANAMLATRISFMNELANLAESLGADIEL
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGSDPRIGWHFLYAGCGYGGSCFPKDVKALIRTAAEQGTALRVLTAVEEANEVQKH
HHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHH
VLIDKIVRRFGTDLSGRRFALWGLAFKPDTDDMREAPSRVVVEELLARGASVTAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHC
GEAERIFGDEPRISYAGRPKSALEGADALVILTEWKEFRSPDFEAIRSRLRTPVVFDGRN
CCHHHHCCCCCCEEECCCCHHHHCCCCEEEEEECHHHHCCCCHHHHHHHCCCCEEECCCC
IYEPSVLRAAGIEYHGIGRP
CCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]