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The map label for this gene is argD [H]

Identifier: 119898479

GI number: 119898479

Start: 2394503

End: 2395693

Strand: Reverse

Name: argD [H]

Synonym: azo2188

Alternate gene names: 119898479

Gene position: 2395693-2394503 (Counterclockwise)

Preceding gene: 119898481

Following gene: 119898478

Centisome position: 54.75

GC content: 65.41

Gene sequence:

>1191_bases
ATGTCCCACGTCATGAACACCTACGCCCGGCTTCCCGTCGCATTCGAGCGCGGCGAAGGGGTCTGGCTGTACGACGATGC
CGGTAAGCGGTACCTCGACGCACTTTCCGGCATTGCGGTATCCACGCTCGGTCACAACCACCCGCGGCTCGTCCGGGCGA
TTGCCGAGCAGGCAGCCGCGGTGCTGCATACCTCCAATCTGTACCGCATTCCCTTGCAGGAAAAGCTGGCGGACCGCCTG
GGTGCGATCTCCGGCATGGACGAGGTTTTCTTCTGCAACTCCGGTTGCGAGGCCAACGAAGCCGCGATCAAGCTCGCCCG
TTTCTATGGGCACAAACGCGGCGTCGCGCAGCCCACCATCATCGTGATGGAGAACGCCTTTCACGGCCGTACGCTGGCGA
CGCTGTCGGCCACGGGCAATCGCAAGGCGCAGGCCGGTTTCGAACCGCTGGTGTCGGGCTTCATCCGCGTGCCTTATCGC
GACATCCAGGCGATTCGTCAGGTGGCGGAGCACAACCAGGACGTGGTTGCGGTCATGCTGGAGATGATCCAGGGCGAGGG
CGGCATCAATCTGGCGGAGGCCGGGTTCCAGCGCGAACTGCGCGAGTTGTGCGACGCGCGCGGATGGCTGTTGATTTGCG
ATGAGGTCCAGTGCGGAGTGGGGCGTACAGGGAAGTGGTTCGGCTGGCAGCATGCCGATGTCCGCCCTGATGTCGTGACG
CTTGCCAAGGGGCTGGGCTCAGGGGTTCCGATTGGCGCCTGCCTGACGAGCGGGGCTGCCGCGGGGCTGTTCGGTCCGGG
TAATCACGGTTCCACGTTCGGCGGAAATCCGCTCGCTTGCGCTGCCGCGCTGACCACGCTCGAAGTCATCGAGGAGTCCG
GTCTGATGGCCCAGGCCGAGGCCGTGGGTGAAACCATCTGCTCAGGGCTGCGCGAGGCGCTCGCGGGGTGCGAAGGCGTT
GTGGAGATACGTGGCCGCGGCTTGATGATCGGTGTGGAACTCGACCGCCCGTGCGGAGCGCTGGTCACGAAGGCGCTCGA
GAACGGTCTTCTGATCAATGTCACTGCCGAGCGGGTGGTGCGCCTGTTGCCCGCGCTCGTCTTCACCGCGGCCGACGCCC
AAGCCCTCGTCGGCGCGCTGGCGCCGCTCATCCGCGACTTCCTGTCGCAGCAAGGAAAAGGTACTGCGTGA

Upstream 100 bases:

>100_bases
GCTATACAGTTCTCCCCCTTTCGCTTAACATTCCCGCTTTATTTTTCACGGCGGCGCGTGCCGCCGTGCGCATTTCTGGT
TCACCTGATCGGGGTTTCCC

Downstream 100 bases:

>100_bases
TGAGTTCGCCCAGACACTATCTTCAGTTCAGCGATTTCACCGCTGCGGAGTACGACCACGTGTTCCAGCGGACGCGCTGG
ATCAAGGAAAAGTTCAAGCA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSHVMNTYARLPVAFERGEGVWLYDDAGKRYLDALSGIAVSTLGHNHPRLVRAIAEQAAAVLHTSNLYRIPLQEKLADRL
GAISGMDEVFFCNSGCEANEAAIKLARFYGHKRGVAQPTIIVMENAFHGRTLATLSATGNRKAQAGFEPLVSGFIRVPYR
DIQAIRQVAEHNQDVVAVMLEMIQGEGGINLAEAGFQRELRELCDARGWLLICDEVQCGVGRTGKWFGWQHADVRPDVVT
LAKGLGSGVPIGACLTSGAAAGLFGPGNHGSTFGGNPLACAAALTTLEVIEESGLMAQAEAVGETICSGLREALAGCEGV
VEIRGRGLMIGVELDRPCGALVTKALENGLLINVTAERVVRLLPALVFTAADAQALVGALAPLIRDFLSQQGKGTA

Sequences:

>Translated_396_residues
MSHVMNTYARLPVAFERGEGVWLYDDAGKRYLDALSGIAVSTLGHNHPRLVRAIAEQAAAVLHTSNLYRIPLQEKLADRL
GAISGMDEVFFCNSGCEANEAAIKLARFYGHKRGVAQPTIIVMENAFHGRTLATLSATGNRKAQAGFEPLVSGFIRVPYR
DIQAIRQVAEHNQDVVAVMLEMIQGEGGINLAEAGFQRELRELCDARGWLLICDEVQCGVGRTGKWFGWQHADVRPDVVT
LAKGLGSGVPIGACLTSGAAAGLFGPGNHGSTFGGNPLACAAALTTLEVIEESGLMAQAEAVGETICSGLREALAGCEGV
VEIRGRGLMIGVELDRPCGALVTKALENGLLINVTAERVVRLLPALVFTAADAQALVGALAPLIRDFLSQQGKGTA
>Mature_395_residues
SHVMNTYARLPVAFERGEGVWLYDDAGKRYLDALSGIAVSTLGHNHPRLVRAIAEQAAAVLHTSNLYRIPLQEKLADRLG
AISGMDEVFFCNSGCEANEAAIKLARFYGHKRGVAQPTIIVMENAFHGRTLATLSATGNRKAQAGFEPLVSGFIRVPYRD
IQAIRQVAEHNQDVVAVMLEMIQGEGGINLAEAGFQRELRELCDARGWLLICDEVQCGVGRTGKWFGWQHADVRPDVVTL
AKGLGSGVPIGACLTSGAAAGLFGPGNHGSTFGGNPLACAAALTTLEVIEESGLMAQAEAVGETICSGLREALAGCEGVV
EIRGRGLMIGVELDRPCGALVTKALENGLLINVTAERVVRLLPALVFTAADAQALVGALAPLIRDFLSQQGKGTA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=33.3333333333333, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI13994255, Length=374, Percent_Identity=35.0267379679144, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=34.3234323432343, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=29.8076923076923, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=29.1866028708134, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=28.8461538461538, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=30.1837270341207, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI188536080, Length=436, Percent_Identity=24.7706422018349, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38679950, Length=436, Percent_Identity=24.7706422018349, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38679946, Length=436, Percent_Identity=24.7706422018349, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1789759, Length=374, Percent_Identity=40.1069518716578, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=39.030612244898, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI145693181, Length=382, Percent_Identity=39.7905759162304, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=33.5802469135802, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=32.0610687022901, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786991, Length=419, Percent_Identity=30.5489260143198, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786349, Length=316, Percent_Identity=30.0632911392405, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=392, Percent_Identity=34.1836734693878, Blast_Score=240, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=33.9449541284404, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=34.7826086956522, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=28.6729857819905, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17541228, Length=422, Percent_Identity=27.9620853080569, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71981843, Length=169, Percent_Identity=33.1360946745562, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71992985, Length=121, Percent_Identity=33.8842975206612, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=379, Percent_Identity=36.9393139841689, Blast_Score=240, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=34.3283582089552, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6321456, Length=436, Percent_Identity=27.0642201834862, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=340, Percent_Identity=24.7058823529412, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357415, Length=370, Percent_Identity=35.6756756756757, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=32.7231121281465, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI161085790, Length=367, Percent_Identity=34.6049046321526, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=29.9043062200957, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI281366494, Length=421, Percent_Identity=26.1282660332542, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24667139, Length=421, Percent_Identity=26.1282660332542, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24667143, Length=421, Percent_Identity=26.1282660332542, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41924; Mature: 41793

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVMNTYARLPVAFERGEGVWLYDDAGKRYLDALSGIAVSTLGHNHPRLVRAIAEQAAA
CCHHHHHHHHCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VLHTSNLYRIPLQEKLADRLGAISGMDEVFFCNSGCEANEAAIKLARFYGHKRGVAQPTI
HHHCCCEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEE
IVMENAFHGRTLATLSATGNRKAQAGFEPLVSGFIRVPYRDIQAIRQVAEHNQDVVAVML
EEEECCCCCCEEEEEECCCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
EMIQGEGGINLAEAGFQRELRELCDARGWLLICDEVQCGVGRTGKWFGWQHADVRPDVVT
HHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
LAKGLGSGVPIGACLTSGAAAGLFGPGNHGSTFGGNPLACAAALTTLEVIEESGLMAQAE
HHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
AVGETICSGLREALAGCEGVVEIRGRGLMIGVELDRPCGALVTKALENGLLINVTAERVV
HHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHCCEEEEEHHHHHH
RLLPALVFTAADAQALVGALAPLIRDFLSQQGKGTA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SHVMNTYARLPVAFERGEGVWLYDDAGKRYLDALSGIAVSTLGHNHPRLVRAIAEQAAA
CHHHHHHHHCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VLHTSNLYRIPLQEKLADRLGAISGMDEVFFCNSGCEANEAAIKLARFYGHKRGVAQPTI
HHHCCCEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEE
IVMENAFHGRTLATLSATGNRKAQAGFEPLVSGFIRVPYRDIQAIRQVAEHNQDVVAVML
EEEECCCCCCEEEEEECCCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
EMIQGEGGINLAEAGFQRELRELCDARGWLLICDEVQCGVGRTGKWFGWQHADVRPDVVT
HHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
LAKGLGSGVPIGACLTSGAAAGLFGPGNHGSTFGGNPLACAAALTTLEVIEESGLMAQAE
HHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
AVGETICSGLREALAGCEGVVEIRGRGLMIGVELDRPCGALVTKALENGLLINVTAERVV
HHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHCCEEEEEHHHHHH
RLLPALVFTAADAQALVGALAPLIRDFLSQQGKGTA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]