| Definition | Azoarcus sp. BH72 chromosome, complete genome. |
|---|---|
| Accession | NC_008702 |
| Length | 4,376,040 |
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The map label for this gene is lon [H]
Identifier: 119898360
GI number: 119898360
Start: 2269613
End: 2271997
Strand: Reverse
Name: lon [H]
Synonym: azo2069
Alternate gene names: 119898360
Gene position: 2271997-2269613 (Counterclockwise)
Preceding gene: 119898361
Following gene: 119898359
Centisome position: 51.92
GC content: 60.96
Gene sequence:
>2385_bases ATGGAACTGCCGCTGTTGCCGCTGCGCGACGTGGTTGTGTTCCCGCATATGGTGATCCCGCTTTTCGTGGGGCGCCCCAA GTCCATCAAGGCGCTCGAAAACGCCATGGAGGCCAGCAAGAGCATTCTGCTGGTTGCTCAGAAGTCGGCCGCGAAGGATG AACCGGCGATCGAAGACCTGTACTCGATCGGCTGCGTCGCCAATATCCTGCAGATGCTGAAGCTGCCCGACGGCACGATC AAAGTGCTGGTGGAAGGGGTTCAGCGCGCACGGATCGACTCCGTCGAAGACCTGAAGCAGTTGTTTGTCGCCAAGGCGAC GCCCATTCCGGTTCCGGAAGTGGACAACAACGAGGTCGAAGCCATGCGGCGCGCGATCATCGCGCAGTTCGACCAGTACG TTAAGCTGAACAAGAAGATCCCGCCGGAGATCCTGACCTCGCTCGCCGGGATCGAGGAGCCGGGCCGTCTTGCGGACACC ATTGCGGCTCATCTTCCCCTTAAGCTCGAGCAGAAGCAGGACGTGCTCGAGATGTTCGACACCGGCGAACGCCTCGACAA GCTGCTTACCCAGCTTGAAACCGAACTCGACATCCTCCAGGTCGAAAAGCGCATCCGCGGGCGCGTGAAGCGCCAGATGG AGAAGAGCCAGCGCGAGTACTACCTGAACGAGCAGGTCAAAGCCATCCAGAAGGAACTCGGGGAGGGCGAGGAGGGCGCT GATCTCGAGGAGATGGACAAGAAGATCAAGTCCGCGGGAATGCCGAAGGACGCCTTGGCCAAAGCGCAGTCCGAATTCAA GAAGCTGCGCCTGATGTCGCCGATGTCGGCTGAAGCCACGGTGGTGCGGAACTACATCGAGACGCTGATCGGCCTGCCGT GGAAAAAGAAGTCCCGCGTCAGCAAGGATCTGGCCGAGGCCGAGAAAGTGCTCGACAAGGATCACTACGGTCTGGAGCGC GTCAAGGAGCGCATCCTTGAATATCTCGCCGTCCAGCAGCGTGTCGACAAGGTCAAGGCCCCGATTCTGTGCCTAGTCGG CCCTCCGGGGGTCGGCAAGACTTCGCTCGGCCAGTCGATCGCGAAAGCCACCAACCGCAAGTTCGTGCGCATGGCGCTTG GCGGCGTGCGCGACGAGGCGGAGATCCGCGGCCACCGCCGCACCTACATCGGTTCGATGCCGGGCAAGATCCTGCAGAAC ATGACCAAGGTGGGTGTCAAGAATCCGCTGTTCCTGCTCGACGAAGTGGACAAACTCGGCCAGGACTTCCGCGGTGATCC GTCGTCCGCGCTGCTCGAGGTGCTGGACCCCGAACAGAACCACACCTTCCAGGACCACTACGTGGAGGTTGATTTCGACC TCTCCGACGTGATGTTCGTCGCCACCGCCAACACCCTCAACGTTCCGGCGCCTTTGCTGGATCGTATGGAAGTGATCCGC CTGTCGGGCTACACCGAGGACGAAAAGGTCAATATCGCCCAACGTTACCTGTTGCCCAAGCAGATCAAGAACAACGGTCT CAAGCGTGACGAGATTTCGGTGACCGAAGAGGCGCTGCGCGATGTGTGCCGCTATTACACCCGCGAGGCGGGGGTCCGCA GCCTGGAGCGCGAGATCTCGAAGATCTGCCGCAAGGTGGTGAAGTCGCTCGTGTTGCGTTCGCGGGCCAGCAAGATCGTC GTCAACGCGAAGAACCTCGACAAGTACCTTGGCGTCCGCAAGTACAGCTTCGGCGTCGCCGAAAAGGCCAATCAGATTGG TCAGGTGACCGGGCTGGCGTGGACGGAGGTGGGCGGCGAGTTGCTGACCGTGGAAGCTGTGGCGCTGCCCGGCAAGGGCA AGGTCATGACGACCGGCAAGCTCGGCGAGGTCATGCAGGAGTCGATCCAGGCTGCGCTGTCGGTGGTACGCAAACGCGCA CGGTCGCTCGGCATCAAGGACGACTTCTACCAGAACAGCGATATCCACATTCACCTGCCGGAAGGTGCGATTCCGAAGGA TGGTCCGTCCGCCGGTATCGCGATCTCCACCGCGCTGGTTTCCGTTCTCACCGGCATTCCGGTCCGTTGCGATGTCGCAA TGACCGGCGAGATCACCTTGCGAGGTGAGGTACTTCCGATCGGTGGCCTCAAGGAAAAACTGCTTGCCGCAGTGCGTGGC GGCATTCGCACGGCGCTGATACCGGAAGAAAACGTCAAGGATCTGGTGGATATCCCCGACAACATCAAGAACGTGATCGA AATCGTTCCGGTGAAGTGGATTGATCAGGTTCTGGAGTTGGCCCTGGAACGAAAGCCGGAGCCGCTGCCGGAGGAGGCTG AGGTTACAGCCGTGGCCCCTGCAGACGAGGCAGCGCGCGCTGCCGCCAACTTGCGCGCGCATTGA
Upstream 100 bases:
>100_bases ACCCGCCGCTTGAATTTCCAGGCCCCGCCCGCATATGGGCGGGGCTACCTTAGAAAGGAAACTGAAAATATCGGGTCCCG TTGACCTCCCCAACGATCAA
Downstream 100 bases:
>100_bases TCGGCCGGGAGCACGGGTCGCTTTGGGCGCCCGTGCTGCCGAACGAAAACGCTCTGCCTTCCAAGCTTGGCAACCTGCTG CCGTTACATCTATAATCTTT
Product: ATP-dependent protease La
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 794; Mature: 794
Protein sequence:
>794_residues MELPLLPLRDVVVFPHMVIPLFVGRPKSIKALENAMEASKSILLVAQKSAAKDEPAIEDLYSIGCVANILQMLKLPDGTI KVLVEGVQRARIDSVEDLKQLFVAKATPIPVPEVDNNEVEAMRRAIIAQFDQYVKLNKKIPPEILTSLAGIEEPGRLADT IAAHLPLKLEQKQDVLEMFDTGERLDKLLTQLETELDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGA DLEEMDKKIKSAGMPKDALAKAQSEFKKLRLMSPMSAEATVVRNYIETLIGLPWKKKSRVSKDLAEAEKVLDKDHYGLER VKERILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSIAKATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQN MTKVGVKNPLFLLDEVDKLGQDFRGDPSSALLEVLDPEQNHTFQDHYVEVDFDLSDVMFVATANTLNVPAPLLDRMEVIR LSGYTEDEKVNIAQRYLLPKQIKNNGLKRDEISVTEEALRDVCRYYTREAGVRSLEREISKICRKVVKSLVLRSRASKIV VNAKNLDKYLGVRKYSFGVAEKANQIGQVTGLAWTEVGGELLTVEAVALPGKGKVMTTGKLGEVMQESIQAALSVVRKRA RSLGIKDDFYQNSDIHIHLPEGAIPKDGPSAGIAISTALVSVLTGIPVRCDVAMTGEITLRGEVLPIGGLKEKLLAAVRG GIRTALIPEENVKDLVDIPDNIKNVIEIVPVKWIDQVLELALERKPEPLPEEAEVTAVAPADEAARAAANLRAH
Sequences:
>Translated_794_residues MELPLLPLRDVVVFPHMVIPLFVGRPKSIKALENAMEASKSILLVAQKSAAKDEPAIEDLYSIGCVANILQMLKLPDGTI KVLVEGVQRARIDSVEDLKQLFVAKATPIPVPEVDNNEVEAMRRAIIAQFDQYVKLNKKIPPEILTSLAGIEEPGRLADT IAAHLPLKLEQKQDVLEMFDTGERLDKLLTQLETELDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGA DLEEMDKKIKSAGMPKDALAKAQSEFKKLRLMSPMSAEATVVRNYIETLIGLPWKKKSRVSKDLAEAEKVLDKDHYGLER VKERILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSIAKATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQN MTKVGVKNPLFLLDEVDKLGQDFRGDPSSALLEVLDPEQNHTFQDHYVEVDFDLSDVMFVATANTLNVPAPLLDRMEVIR LSGYTEDEKVNIAQRYLLPKQIKNNGLKRDEISVTEEALRDVCRYYTREAGVRSLEREISKICRKVVKSLVLRSRASKIV VNAKNLDKYLGVRKYSFGVAEKANQIGQVTGLAWTEVGGELLTVEAVALPGKGKVMTTGKLGEVMQESIQAALSVVRKRA RSLGIKDDFYQNSDIHIHLPEGAIPKDGPSAGIAISTALVSVLTGIPVRCDVAMTGEITLRGEVLPIGGLKEKLLAAVRG GIRTALIPEENVKDLVDIPDNIKNVIEIVPVKWIDQVLELALERKPEPLPEEAEVTAVAPADEAARAAANLRAH >Mature_794_residues MELPLLPLRDVVVFPHMVIPLFVGRPKSIKALENAMEASKSILLVAQKSAAKDEPAIEDLYSIGCVANILQMLKLPDGTI KVLVEGVQRARIDSVEDLKQLFVAKATPIPVPEVDNNEVEAMRRAIIAQFDQYVKLNKKIPPEILTSLAGIEEPGRLADT IAAHLPLKLEQKQDVLEMFDTGERLDKLLTQLETELDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGA DLEEMDKKIKSAGMPKDALAKAQSEFKKLRLMSPMSAEATVVRNYIETLIGLPWKKKSRVSKDLAEAEKVLDKDHYGLER VKERILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSIAKATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQN MTKVGVKNPLFLLDEVDKLGQDFRGDPSSALLEVLDPEQNHTFQDHYVEVDFDLSDVMFVATANTLNVPAPLLDRMEVIR LSGYTEDEKVNIAQRYLLPKQIKNNGLKRDEISVTEEALRDVCRYYTREAGVRSLEREISKICRKVVKSLVLRSRASKIV VNAKNLDKYLGVRKYSFGVAEKANQIGQVTGLAWTEVGGELLTVEAVALPGKGKVMTTGKLGEVMQESIQAALSVVRKRA RSLGIKDDFYQNSDIHIHLPEGAIPKDGPSAGIAISTALVSVLTGIPVRCDVAMTGEITLRGEVLPIGGLKEKLLAAVRG GIRTALIPEENVKDLVDIPDNIKNVIEIVPVKWIDQVLELALERKPEPLPEEAEVTAVAPADEAARAAANLRAH
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI31377667, Length=564, Percent_Identity=46.0992907801418, Blast_Score=520, Evalue=1e-147, Organism=Homo sapiens, GI21396489, Length=843, Percent_Identity=36.6548042704626, Blast_Score=500, Evalue=1e-141, Organism=Escherichia coli, GI1786643, Length=767, Percent_Identity=68.4485006518905, Blast_Score=1078, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=701, Percent_Identity=39.5149786019972, Blast_Score=490, Evalue=1e-138, Organism=Caenorhabditis elegans, GI17556486, Length=789, Percent_Identity=33.3333333333333, Blast_Score=429, Evalue=1e-120, Organism=Saccharomyces cerevisiae, GI6319449, Length=711, Percent_Identity=39.5218002812939, Blast_Score=499, Evalue=1e-142, Organism=Drosophila melanogaster, GI24666867, Length=687, Percent_Identity=41.6302765647744, Blast_Score=504, Evalue=1e-142, Organism=Drosophila melanogaster, GI221513036, Length=687, Percent_Identity=41.6302765647744, Blast_Score=503, Evalue=1e-142,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 87959; Mature: 87959
Theoretical pI: Translated: 7.58; Mature: 7.58
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELPLLPLRDVVVFPHMVIPLFVGRPKSIKALENAMEASKSILLVAQKSAAKDEPAIEDL CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH YSIGCVANILQMLKLPDGTIKVLVEGVQRARIDSVEDLKQLFVAKATPIPVPEVDNNEVE HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHH AMRRAIIAQFDQYVKLNKKIPPEILTSLAGIEEPGRLADTIAAHLPLKLEQKQDVLEMFD HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH TGERLDKLLTQLETELDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGA CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC DLEEMDKKIKSAGMPKDALAKAQSEFKKLRLMSPMSAEATVVRNYIETLIGLPWKKKSRV CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH SKDLAEAEKVLDKDHYGLERVKERILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSI HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH AKATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQNMTKVGVKNPLFLLDEVDKLG HHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH QDFRGDPSSALLEVLDPEQNHTFQDHYVEVDFDLSDVMFVATANTLNVPAPLLDRMEVIR HHCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHEEEEEECCCCCCCHHHHHHHHHHH LSGYTEDEKVNIAQRYLLPKQIKNNGLKRDEISVTEEALRDVCRYYTREAGVRSLEREIS HCCCCCCHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KICRKVVKSLVLRSRASKIVVNAKNLDKYLGVRKYSFGVAEKANQIGQVTGLAWTEVGGE HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCHHHHCCCC LLTVEAVALPGKGKVMTTGKLGEVMQESIQAALSVVRKRARSLGIKDDFYQNSDIHIHLP EEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC EGAIPKDGPSAGIAISTALVSVLTGIPVRCDVAMTGEITLRGEVLPIGGLKEKLLAAVRG CCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCEEEECEEEECCCHHHHHHHHHHC GIRTALIPEENVKDLVDIPDNIKNVIEIVPVKWIDQVLELALERKPEPLPEEAEVTAVAP CCCEECCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECC ADEAARAAANLRAH CHHHHHHHHHCCCC >Mature Secondary Structure MELPLLPLRDVVVFPHMVIPLFVGRPKSIKALENAMEASKSILLVAQKSAAKDEPAIEDL CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH YSIGCVANILQMLKLPDGTIKVLVEGVQRARIDSVEDLKQLFVAKATPIPVPEVDNNEVE HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHH AMRRAIIAQFDQYVKLNKKIPPEILTSLAGIEEPGRLADTIAAHLPLKLEQKQDVLEMFD HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH TGERLDKLLTQLETELDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQKELGEGEEGA CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC DLEEMDKKIKSAGMPKDALAKAQSEFKKLRLMSPMSAEATVVRNYIETLIGLPWKKKSRV CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH SKDLAEAEKVLDKDHYGLERVKERILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSI HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH AKATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQNMTKVGVKNPLFLLDEVDKLG HHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH QDFRGDPSSALLEVLDPEQNHTFQDHYVEVDFDLSDVMFVATANTLNVPAPLLDRMEVIR HHCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHEEEEEECCCCCCCHHHHHHHHHHH LSGYTEDEKVNIAQRYLLPKQIKNNGLKRDEISVTEEALRDVCRYYTREAGVRSLEREIS HCCCCCCHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KICRKVVKSLVLRSRASKIVVNAKNLDKYLGVRKYSFGVAEKANQIGQVTGLAWTEVGGE HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCHHHHCCCC LLTVEAVALPGKGKVMTTGKLGEVMQESIQAALSVVRKRARSLGIKDDFYQNSDIHIHLP EEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC EGAIPKDGPSAGIAISTALVSVLTGIPVRCDVAMTGEITLRGEVLPIGGLKEKLLAAVRG CCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCEEEECEEEECCCHHHHHHHHHHC GIRTALIPEENVKDLVDIPDNIKNVIEIVPVKWIDQVLELALERKPEPLPEEAEVTAVAP CCCEECCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECC ADEAARAAANLRAH CHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8981986; 12620739 [H]