Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 119898361

GI number: 119898361

Start: 2272107

End: 2273375

Strand: Reverse

Name: clpX [H]

Synonym: azo2070

Alternate gene names: 119898361

Gene position: 2273375-2272107 (Counterclockwise)

Preceding gene: 119898362

Following gene: 119898360

Centisome position: 51.95

GC content: 60.6

Gene sequence:

>1269_bases
ATGACGGAAAAGAAGACGGGCGGCGAAAAGCTGCTTTACTGCTCGTTTTGTGGCAAGAGCCAGCATGAGGTACGCAAGCT
TATCGCAGGGCCGTCCGTCTTCATCTGCGACGAGTGCATCGAACTCTGCAACGACATCATCCGGGACGAGATCGCCGGCA
GCGTCGAGACCGAGGGCGTGAAGGGCAAGCTGCCCACGCCGCACGAGATCTGCCAGATTCTCGACCAATACGTCATCGGC
CAGGCCCAGGCGAAGCGCAACCTCTCCGTTGCGGTGTACAACCACTACAAGCGGCTGCGCCACCTCAGTGGCCGTCAGGA
CGAGGTCGAGCTTTCCAAGTCGAACATTCTCCTGATCGGACCGACCGGGTCGGGCAAGACGCTGCTTGCGCAAACGCTCG
CGCGCCTGCTCAACGTACCCTTCGTCATGGCGGATGCGACGACCCTGACCGAGGCCGGTTACGTCGGCGAAGACGTCGAG
AACATCATCCAGAAGCTGCTGCAGAAGTGCGACTACGACGTCGAGAAGGCGCAGCAGGGGATCGTGTATATCGACGAGAT
CGACAAGATTTCGCGCAAGTCGGATAACCCGTCGATCACGCGTGACGTGTCGGGCGAAGGCGTGCAGCAGGCCCTGCTGA
AGCTGATCGAGGGCACGATCGCGTCGATCCCGCCGCAGGGCGGGCGCAAGCATCCGAATCAGGACTTCATCCAGGTCGAC
ACCACCAACGTGTTGTTCATCTGCGGCGGGGCTTTCGACGGCCTGGACAAGGTGATCCGCAACCGGACCGAAAAGATGGG
TATCGGTTTTGGCGCCGAAGTAAAGAGCCGGCAAGGGAAGAACCTCACCGAGACCTTCCGCCAGGTGGAGCCCGAGGATC
TCGTCAAGTTCGGCCTCATCCCCGAATTCGTCGGACGCCTGCCTGTCGTCGCCACCTTGCAGGAACTGGATGAGGACGCA
CTGATCCAGATCCTGATCGAACCCAAGAACGCGCTGGTGAAGCAGTACCAGAAACTCTTCTCGATGGAAGGGGTCGATCT
GGAAATCCGGCCTGCCGCGTTGCATGCGGTGGCGCGAAAGGCGATCAAGCGCAAGACCGGCGCCCGCGGTCTGCGTTCGA
TCCTCGAGGCGGCACTGTTGGACATCATGTACGACCTGCCGCAGCTCGACGGCGTGGAAAAGGTCGTGGTAGACGAAAAC
ACGATCGAGGAAGGCAGCAAGCCGCTGCTGATCTACGCTGAACAACCGAAGGTGTCCGGCTCGAACTGA

Upstream 100 bases:

>100_bases
ACCGCGACAACTTCATGTCCGCGACCGCCGCCGTGGAGTACGGCCTGGTGGACAAGGTCCTGACCAGCCGCGCCGATACC
TGAACCAGGAGAATCCGAAA

Downstream 100 bases:

>100_bases
CACCTTTCAACCCGCCGCTTGAATTTCCAGGCCCCGCCCGCATATGGGCGGGGCTACCTTAGAAAGGAAACTGAAAATAT
CGGGTCCCGTTGACCTCCCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTEKKTGGEKLLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIIRDEIAGSVETEGVKGKLPTPHEICQILDQYVIG
QAQAKRNLSVAVYNHYKRLRHLSGRQDEVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPNQDFIQVD
TTNVLFICGGAFDGLDKVIRNRTEKMGIGFGAEVKSRQGKNLTETFRQVEPEDLVKFGLIPEFVGRLPVVATLQELDEDA
LIQILIEPKNALVKQYQKLFSMEGVDLEIRPAALHAVARKAIKRKTGARGLRSILEAALLDIMYDLPQLDGVEKVVVDEN
TIEEGSKPLLIYAEQPKVSGSN

Sequences:

>Translated_422_residues
MTEKKTGGEKLLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIIRDEIAGSVETEGVKGKLPTPHEICQILDQYVIG
QAQAKRNLSVAVYNHYKRLRHLSGRQDEVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPNQDFIQVD
TTNVLFICGGAFDGLDKVIRNRTEKMGIGFGAEVKSRQGKNLTETFRQVEPEDLVKFGLIPEFVGRLPVVATLQELDEDA
LIQILIEPKNALVKQYQKLFSMEGVDLEIRPAALHAVARKAIKRKTGARGLRSILEAALLDIMYDLPQLDGVEKVVVDEN
TIEEGSKPLLIYAEQPKVSGSN
>Mature_421_residues
TEKKTGGEKLLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIIRDEIAGSVETEGVKGKLPTPHEICQILDQYVIGQ
AQAKRNLSVAVYNHYKRLRHLSGRQDEVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPNQDFIQVDT
TNVLFICGGAFDGLDKVIRNRTEKMGIGFGAEVKSRQGKNLTETFRQVEPEDLVKFGLIPEFVGRLPVVATLQELDEDAL
IQILIEPKNALVKQYQKLFSMEGVDLEIRPAALHAVARKAIKRKTGARGLRSILEAALLDIMYDLPQLDGVEKVVVDENT
IEEGSKPLLIYAEQPKVSGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=336, Percent_Identity=51.7857142857143, Blast_Score=322, Evalue=5e-88,
Organism=Escherichia coli, GI1786642, Length=417, Percent_Identity=75.5395683453237, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1790366, Length=107, Percent_Identity=45.7943925233645, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=322, Percent_Identity=45.6521739130435, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=322, Percent_Identity=45.6521739130435, Blast_Score=277, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=402, Percent_Identity=38.3084577114428, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=40.5622489959839, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=41.0798122065728, Blast_Score=278, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24648291, Length=306, Percent_Identity=46.7320261437908, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648289, Length=306, Percent_Identity=46.7320261437908, Blast_Score=282, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46522; Mature: 46391

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKTGGEKLLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIIRDEIAGSVETEGV
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCC
KGKLPTPHEICQILDQYVIGQAQAKRNLSVAVYNHYKRLRHLSGRQDEVELSKSNILLIG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEECCCCEEEEE
PTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQG
CCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPNQDFIQVD
CEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
TTNVLFICGGAFDGLDKVIRNRTEKMGIGFGAEVKSRQGKNLTETFRQVEPEDLVKFGLI
CCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHCCHHHHHHHCCC
PEFVGRLPVVATLQELDEDALIQILIEPKNALVKQYQKLFSMEGVDLEIRPAALHAVARK
HHHHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHH
AIKRKTGARGLRSILEAALLDIMYDLPQLDGVEKVVVDENTIEEGSKPLLIYAEQPKVSG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCCCCCEEEEECCCCCCC
SN
CC
>Mature Secondary Structure 
TEKKTGGEKLLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIIRDEIAGSVETEGV
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCC
KGKLPTPHEICQILDQYVIGQAQAKRNLSVAVYNHYKRLRHLSGRQDEVELSKSNILLIG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEECCCCEEEEE
PTGSGKTLLAQTLARLLNVPFVMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQG
CCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPNQDFIQVD
CEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
TTNVLFICGGAFDGLDKVIRNRTEKMGIGFGAEVKSRQGKNLTETFRQVEPEDLVKFGLI
CCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHCCHHHHHHHCCC
PEFVGRLPVVATLQELDEDALIQILIEPKNALVKQYQKLFSMEGVDLEIRPAALHAVARK
HHHHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHH
AIKRKTGARGLRSILEAALLDIMYDLPQLDGVEKVVVDENTIEEGSKPLLIYAEQPKVSG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCCCCCEEEEECCCCCCC
SN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA