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The map label for this gene is galU [H]

Identifier: 119898291

GI number: 119898291

Start: 2202353

End: 2203258

Strand: Reverse

Name: galU [H]

Synonym: azo2000

Alternate gene names: 119898291

Gene position: 2203258-2202353 (Counterclockwise)

Preceding gene: 119898292

Following gene: 119898289

Centisome position: 50.35

GC content: 64.02

Gene sequence:

>906_bases
ATGAAAAAGGTCACCAAGGCGGTCTTTCCGGTTGCGGGCATGGGCACGCGCTTCCTGCCGGCCACCAAGGCCAGTCCGAA
GGAAATGCTGCCGGTCGTCGACAAGCCGCTGATCCAGTACGCGGTCGAAGAAGCCGTCGCTGCCGGCATCACCGACATGA
TCTTCATCACCGGCCGCACCAAGCGTGCGATCGAGGACCACTTCGACAAGGCCTACGAACTCGAGACCGAACTCGAAGCC
CGCGGCAAGAAGGAACTGCTGGAAGTGGTCGCCAAGACCGTGCCCAAGGGCATGAACTGCGTCTACATCCGCCAGTCCGA
AGCGCTCGGCCTCGGCCACGCGGTGCTGTGCGCCTCCGCGGTGGTGGGCGACGACGAGCCCTTCGCGGTCATTCTCGCCG
ACGACCTGCTCGACAACCACGGCGGCAAGCCGGTGATGGCGCAGATGAGCGAGGTCTATAACTATCACCGCTGCTCGGTG
CTCGGCACCATGAACGTGCCGCGCCAGGAAACCCGCCAGTACGGCATCGTCAGCACCGAAAGCCAGAGCGGCAACATCCA
GCGCGTGACCGGCATCGTCGAAAAGCCGAAGCCCGAGGAAGCGCCGACGACCCAGGCCGTCGTCGGCCGCTACATCCTGA
CCCCGCGCATTTTCGAGCATCTGCGCGCGCTCAAGCCGGGCGCCGGTGGCGAACTGCAGCTGACCGATGCGATCGCCTCG
CTGCTGAAGGAAGAAGCGGTGCTCTCCTACCAGTACGAGGGCGTGCGCTATGACTGCGGCTCCAAGCTCGGCTACCTGAA
GGCTGCGGTGGAATTCGGCCTGCGCCACCATGAAGTGGGGGCTGAATTCGCGGCCTACCTCAACGACCGCTTCCCGGGCG
AGTTGGCGAAGAAGAAGGAAAAGTAA

Upstream 100 bases:

>100_bases
CGCAGGATCTCGGGGTGGACATCGTCGATGAGGACGGTCTGCGCCGATTGCTGGAATCGGGCGAACAGTCGCCCATCAAC
AACAAGGACGGAGTCCCAGA

Downstream 100 bases:

>100_bases
GCCGCAGCGGCGGGGGCGGGCAGCGCCTGCCTCCTGCTACGGCGGATGTGGGAAGCGCCGCGGACCGCGGCGCTTTTTTT
TCGCCTGTCGATCGGGGGAG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKKVTKAVFPVAGMGTRFLPATKASPKEMLPVVDKPLIQYAVEEAVAAGITDMIFITGRTKRAIEDHFDKAYELETELEA
RGKKELLEVVAKTVPKGMNCVYIRQSEALGLGHAVLCASAVVGDDEPFAVILADDLLDNHGGKPVMAQMSEVYNYHRCSV
LGTMNVPRQETRQYGIVSTESQSGNIQRVTGIVEKPKPEEAPTTQAVVGRYILTPRIFEHLRALKPGAGGELQLTDAIAS
LLKEEAVLSYQYEGVRYDCGSKLGYLKAAVEFGLRHHEVGAEFAAYLNDRFPGELAKKKEK

Sequences:

>Translated_301_residues
MKKVTKAVFPVAGMGTRFLPATKASPKEMLPVVDKPLIQYAVEEAVAAGITDMIFITGRTKRAIEDHFDKAYELETELEA
RGKKELLEVVAKTVPKGMNCVYIRQSEALGLGHAVLCASAVVGDDEPFAVILADDLLDNHGGKPVMAQMSEVYNYHRCSV
LGTMNVPRQETRQYGIVSTESQSGNIQRVTGIVEKPKPEEAPTTQAVVGRYILTPRIFEHLRALKPGAGGELQLTDAIAS
LLKEEAVLSYQYEGVRYDCGSKLGYLKAAVEFGLRHHEVGAEFAAYLNDRFPGELAKKKEK
>Mature_301_residues
MKKVTKAVFPVAGMGTRFLPATKASPKEMLPVVDKPLIQYAVEEAVAAGITDMIFITGRTKRAIEDHFDKAYELETELEA
RGKKELLEVVAKTVPKGMNCVYIRQSEALGLGHAVLCASAVVGDDEPFAVILADDLLDNHGGKPVMAQMSEVYNYHRCSV
LGTMNVPRQETRQYGIVSTESQSGNIQRVTGIVEKPKPEEAPTTQAVVGRYILTPRIFEHLRALKPGAGGELQLTDAIAS
LLKEEAVLSYQYEGVRYDCGSKLGYLKAAVEFGLRHHEVGAEFAAYLNDRFPGELAKKKEK

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=293, Percent_Identity=47.7815699658703, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1788355, Length=285, Percent_Identity=43.5087719298246, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1788351, Length=276, Percent_Identity=25.7246376811594, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790224, Length=230, Percent_Identity=23.9130434782609, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33011; Mature: 33011

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVTKAVFPVAGMGTRFLPATKASPKEMLPVVDKPLIQYAVEEAVAAGITDMIFITGRT
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
KRAIEDHFDKAYELETELEARGKKELLEVVAKTVPKGMNCVYIRQSEALGLGHAVLCASA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHH
VVGDDEPFAVILADDLLDNHGGKPVMAQMSEVYNYHRCSVLGTMNVPRQETRQYGIVSTE
HCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCEEEC
SQSGNIQRVTGIVEKPKPEEAPTTQAVVGRYILTPRIFEHLRALKPGAGGELQLTDAIAS
CCCCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEHHHHHHH
LLKEEAVLSYQYEGVRYDCGSKLGYLKAAVEFGLRHHEVGAEFAAYLNDRFPGELAKKKE
HHHHHHHHHEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
K
C
>Mature Secondary Structure
MKKVTKAVFPVAGMGTRFLPATKASPKEMLPVVDKPLIQYAVEEAVAAGITDMIFITGRT
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
KRAIEDHFDKAYELETELEARGKKELLEVVAKTVPKGMNCVYIRQSEALGLGHAVLCASA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHH
VVGDDEPFAVILADDLLDNHGGKPVMAQMSEVYNYHRCSVLGTMNVPRQETRQYGIVSTE
HCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCEEEC
SQSGNIQRVTGIVEKPKPEEAPTTQAVVGRYILTPRIFEHLRALKPGAGGELQLTDAIAS
CCCCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEHHHHHHH
LLKEEAVLSYQYEGVRYDCGSKLGYLKAAVEFGLRHHEVGAEFAAYLNDRFPGELAKKKE
HHHHHHHHHEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]