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The map label for this gene is ohpC [H]

Identifier: 119898267

GI number: 119898267

Start: 2172426

End: 2173322

Strand: Reverse

Name: ohpC [H]

Synonym: azo1976

Alternate gene names: 119898267

Gene position: 2173322-2172426 (Counterclockwise)

Preceding gene: 119898268

Following gene: 119898266

Centisome position: 49.66

GC content: 67.67

Gene sequence:

>897_bases
TTGCAAACCTCCTACCAAAGCATCTGGGCCGAACTCAGGCAGACCAGCTTCAGCCAGGGCTGGACCGACGCCGGCGGCAT
CAACACGCGTTACCTGCACTGCGGCGACCGAGCCGCCCCGGCGCTCATCCTGCTGCACGGCGTCGGCGGGCACGCCGAGG
CCTACGTGCGCAATCTCAAGTCGCACGGCCGTCATTTCTCCACCTGGGCGATCGACATGATCGGCCACGGCTGGACCGAC
CTCGCCACCCGCGATCTGGAAATTCCCGCCTACATCGACCACCTGCTGCGCTTCATGGACGCGCAGCGCATCGAGCGCGC
CAGCTTCTCCGGCGAGTCGCTGGGCGGCTGGGTCGCCGCGCGCATGGCGATCGACCATCCAGATCGGGTCGAGCGCCTCG
TGCTGAATACCGCCGGCGGCTCGCAAGCCGATCCGGTGGTGATGGAGCGGCTCAAGACGCTGTCGCTCCAGGCCGCCACC
GACCCGAGCTGGAACTTCATCAAGGCGCGTGTCGAATGGCTGATGGCCGACAAGTCCAAGGCCTACGACGACCTGATCGC
CACCCGCCAGGCGATCTACTCGCGCCCGGGCATGGCCGCTGCGATGAAGCACAACATGGTGCTGCAGGACATGGAGACGC
GCCTGCGCAACCTGCTGCGCGCCGAGGACTACGCGTGCATCACGGCACCCACGCTGGTGCTGTGGACCTCGCACGACCCC
ACCGCGAACGTCGCCGAAGGGCGCCGGATCGCGTCGATGATCCCGGGCGCGCTGTTCACCGTGATGGAGGGCTGCGGCCA
CTGGCCGCAGTTCGAGGACGCCCAGGTTTTCAATCGCATCCATCTCGCCTTTCTGCTCGGCGGCCACGTGCCCGAAGCCG
TCGCGGCGGGCGGCTGA

Upstream 100 bases:

>100_bases
GGGGAGGGGACAAGACCGACTCGCTCGCCAAGCCTGTCCTCCCGATTCGAAAGGGAGGGAGCACCACCCCATTCCCCTTC
CCCCCCCCGGAGCCCCCACC

Downstream 100 bases:

>100_bases
TTGCGCCGCGGAGGAGACACCGGAATGAGCGCGATGCTGCAATGCATGTCGCATACCCCGCTGAAGGGCTATTTCGACCC
GGCGGCGGACGTGGTGGAGG

Product: 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase

Products: NA

Alternate protein names: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQTSYQSIWAELRQTSFSQGWTDAGGINTRYLHCGDRAAPALILLHGVGGHAEAYVRNLKSHGRHFSTWAIDMIGHGWTD
LATRDLEIPAYIDHLLRFMDAQRIERASFSGESLGGWVAARMAIDHPDRVERLVLNTAGGSQADPVVMERLKTLSLQAAT
DPSWNFIKARVEWLMADKSKAYDDLIATRQAIYSRPGMAAAMKHNMVLQDMETRLRNLLRAEDYACITAPTLVLWTSHDP
TANVAEGRRIASMIPGALFTVMEGCGHWPQFEDAQVFNRIHLAFLLGGHVPEAVAAGG

Sequences:

>Translated_298_residues
MQTSYQSIWAELRQTSFSQGWTDAGGINTRYLHCGDRAAPALILLHGVGGHAEAYVRNLKSHGRHFSTWAIDMIGHGWTD
LATRDLEIPAYIDHLLRFMDAQRIERASFSGESLGGWVAARMAIDHPDRVERLVLNTAGGSQADPVVMERLKTLSLQAAT
DPSWNFIKARVEWLMADKSKAYDDLIATRQAIYSRPGMAAAMKHNMVLQDMETRLRNLLRAEDYACITAPTLVLWTSHDP
TANVAEGRRIASMIPGALFTVMEGCGHWPQFEDAQVFNRIHLAFLLGGHVPEAVAAGG
>Mature_298_residues
MQTSYQSIWAELRQTSFSQGWTDAGGINTRYLHCGDRAAPALILLHGVGGHAEAYVRNLKSHGRHFSTWAIDMIGHGWTD
LATRDLEIPAYIDHLLRFMDAQRIERASFSGESLGGWVAARMAIDHPDRVERLVLNTAGGSQADPVVMERLKTLSLQAAT
DPSWNFIKARVEWLMADKSKAYDDLIATRQAIYSRPGMAAAMKHNMVLQDMETRLRNLLRAEDYACITAPTLVLWTSHDP
TANVAEGRRIASMIPGALFTVMEGCGHWPQFEDAQVFNRIHLAFLLGGHVPEAVAAGG

Specific function: Catalyzes the hydrolysis of a carbon-carbon bond in 4,5- 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oic acid (4,9-DSHA) to yield 9,17-dioxo-1,2,3,4,10,19- hexanorandrostan-5-oic acid (DOHNAA) and 2-hydroxy-hexa-2,4- dienoic acid (HHD). Al

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HsaD family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=266, Percent_Identity=27.0676691729323, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 33022; Mature: 33022

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSYQSIWAELRQTSFSQGWTDAGGINTRYLHCGDRAAPALILLHGVGGHAEAYVRNLK
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHH
SHGRHFSTWAIDMIGHGWTDLATRDLEIPAYIDHLLRFMDAQRIERASFSGESLGGWVAA
HCCCEEHHEEHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RMAIDHPDRVERLVLNTAGGSQADPVVMERLKTLSLQAATDPSWNFIKARVEWLMADKSK
HHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHH
AYDDLIATRQAIYSRPGMAAAMKHNMVLQDMETRLRNLLRAEDYACITAPTLVLWTSHDP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCC
TANVAEGRRIASMIPGALFTVMEGCGHWPQFEDAQVFNRIHLAFLLGGHVPEAVAAGG
CCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MQTSYQSIWAELRQTSFSQGWTDAGGINTRYLHCGDRAAPALILLHGVGGHAEAYVRNLK
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHH
SHGRHFSTWAIDMIGHGWTDLATRDLEIPAYIDHLLRFMDAQRIERASFSGESLGGWVAA
HCCCEEHHEEHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RMAIDHPDRVERLVLNTAGGSQADPVVMERLKTLSLQAATDPSWNFIKARVEWLMADKSK
HHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHH
AYDDLIATRQAIYSRPGMAAAMKHNMVLQDMETRLRNLLRAEDYACITAPTLVLWTSHDP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCC
TANVAEGRRIASMIPGALFTVMEGCGHWPQFEDAQVFNRIHLAFLLGGHVPEAVAAGG
CCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA