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The map label for this gene is pgsA [H]

Identifier: 119897940

GI number: 119897940

Start: 1809267

End: 1809839

Strand: Direct

Name: pgsA [H]

Synonym: azo1649

Alternate gene names: 119897940

Gene position: 1809267-1809839 (Clockwise)

Preceding gene: 119897939

Following gene: 119897941

Centisome position: 41.34

GC content: 63.18

Gene sequence:

>573_bases
ATGTCATTCAACATACCCAATTCGCTCACCTGGGCACGCATCGCGCTGATTCCCATCTTCGTCGGCATCTTCTACGCGCC
GGACGGCTGGATCGGACCCGCACAGAAGAACCTCGTCGCCACCGCGATCTTCATCGTCGCAGCGATCACCGACTGGTTCG
ACGGCTACCTCGCACGGGCGCTGCGCCAGACGTCCGCGTTCGGCGCCTTCCTCGATCCCGTCGCCGACAAGCTGATGGTG
GCGGCGGCGCTGATCCTGCTGGTCCAGTTGGCGCGGGTGGATGCCATCATCGCGGTGGTGATCATCGGCAGGGAGATCAC
CATCTCTGCATTGCGCGAGTGGATGGCGCGCGTCGGCGAATCCTCCAGCGTGGCGGTAGCCTACGTCGGCAAGCTGAAGA
CCGCGGCCCAGATGACAGCCATTCCGCTGCTGCTATACAATGGCCAACTCTTGTCGATCGACCTGCGCTTCATTGGCAGT
GTGCTGATCTACGTCGCTGCCGCGCTGACCCTGTGGTCCATGGGCTACTACCTGCATCGCGCGGCACCCCGGCTGGCACG
GCACAAGGATTGA

Upstream 100 bases:

>100_bases
GCTGATCTGCTTCCGCGCGCCGGCCGGGACAACAGCCGAACCGGCACCCTTAACCGCTATACTCGCCGGTGCATTCAACG
CAGGCCGCCGGCCGCTTCGC

Downstream 100 bases:

>100_bases
GAAGTAGATAGAAAGCTTGACAGTGTTAAATTTCTGCCTATAATGGCGGTCTTTCCCGAGCGGGAATAGCTCAGTTGGTA
GAGCGCAACCTTGCCAAGGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSFNIPNSLTWARIALIPIFVGIFYAPDGWIGPAQKNLVATAIFIVAAITDWFDGYLARALRQTSAFGAFLDPVADKLMV
AAALILLVQLARVDAIIAVVIIGREITISALREWMARVGESSSVAVAYVGKLKTAAQMTAIPLLLYNGQLLSIDLRFIGS
VLIYVAAALTLWSMGYYLHRAAPRLARHKD

Sequences:

>Translated_190_residues
MSFNIPNSLTWARIALIPIFVGIFYAPDGWIGPAQKNLVATAIFIVAAITDWFDGYLARALRQTSAFGAFLDPVADKLMV
AAALILLVQLARVDAIIAVVIIGREITISALREWMARVGESSSVAVAYVGKLKTAAQMTAIPLLLYNGQLLSIDLRFIGS
VLIYVAAALTLWSMGYYLHRAAPRLARHKD
>Mature_189_residues
SFNIPNSLTWARIALIPIFVGIFYAPDGWIGPAQKNLVATAIFIVAAITDWFDGYLARALRQTSAFGAFLDPVADKLMVA
AALILLVQLARVDAIIAVVIIGREITISALREWMARVGESSSVAVAYVGKLKTAAQMTAIPLLLYNGQLLSIDLRFIGSV
LIYVAAALTLWSMGYYLHRAAPRLARHKD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=183, Percent_Identity=50.8196721311475, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20691; Mature: 20560

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNIPNSLTWARIALIPIFVGIFYAPDGWIGPAQKNLVATAIFIVAAITDWFDGYLARA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQTSAFGAFLDPVADKLMVAAALILLVQLARVDAIIAVVIIGREITISALREWMARVGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
SSSVAVAYVGKLKTAAQMTAIPLLLYNGQLLSIDLRFIGSVLIYVAAALTLWSMGYYLHR
CCCCHHHHHHHHHHHHHHHHHHHHEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAPRLARHKD
HHHHHHCCCC
>Mature Secondary Structure 
SFNIPNSLTWARIALIPIFVGIFYAPDGWIGPAQKNLVATAIFIVAAITDWFDGYLARA
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQTSAFGAFLDPVADKLMVAAALILLVQLARVDAIIAVVIIGREITISALREWMARVGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
SSSVAVAYVGKLKTAAQMTAIPLLLYNGQLLSIDLRFIGSVLIYVAAALTLWSMGYYLHR
CCCCHHHHHHHHHHHHHHHHHHHHEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAPRLARHKD
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]