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The map label for this gene is cph1 [H]

Identifier: 119897875

GI number: 119897875

Start: 1741890

End: 1743509

Strand: Reverse

Name: cph1 [H]

Synonym: azo1584

Alternate gene names: 119897875

Gene position: 1743509-1741890 (Counterclockwise)

Preceding gene: 119897876

Following gene: 119897873

Centisome position: 39.84

GC content: 65.62

Gene sequence:

>1620_bases
ATGAGCAGGTTGCGAATTCTGCATATCGAGGACGATCACGACGACGCCGACCTGATTCACCACGCCGCGACCCGCCTCGG
CGTACCGCCAGACTGGACCATGGCCGAATCACGGCCCGCCTTTCTGGAAGCGCTGACCGGGCGCGATTTCGATCTGGTCC
TGTCCGACAGCCGCGTACCCGGAATGGACGGCCAGGAAGCGATGCGGCTGGTGCGCGAACGCCACCCGGACCTGCCCTTC
GTCTTCGTCAGTGGCACCGATGATCCCCTGTGGGTGGAGCAGTGTTTCCGCCAGGGGGCGTACGACCACGTATCCAAGGA
CCAGTTGTGGCGTCTCGTGCCCGTGCTGCAGGGTGTGGGTGCCGAAGCGGAACGCCGGCGCCTGGCGCGGCTGGCGCGGG
CGCATGCGCTGCTGGTGGAAATCGTCAAGCAGTTGTCGCTCGCGCGCAGCCTCGATGCAGTGGTCGATATCGTCAAGAGC
GGAGCACGCCAGCTCAATGGCGCGGACGGGGCAACTTTCGTGCTGCGCGAAGGCGACCACTGTCACTACGTCGCCGAGGA
CGCGATCGGCCCGCTGTGGCAGGGACGGCGTTTTCCCCTGCGCGCCTGCATCAGCGGGTGGGCCATGCTGGAGGGCCGCG
CGGCGGTGGTTCCCGATATCTACGCCGACGAGCGGATTCCCGCCGACGCCTACCGGCCGACCTTCGTGAAAAGTCTGGTC
ATGGTACCGATCCGCGCCGAAGCGCCGATCGGCGCCATCGGCAACTATTGGGCCCATCCGCACGAGGCCACGCCGGAAGA
GGTGGAACTCATCCAGGCACTCGCCGATTCCACCTCGCTGGCGCTGGAGAATCTTTCCCTCTACCGCGACCTTGAACGTC
GGGTGCGCGACCGCACCCGACGCCTGCAGGCTGCAAACGCCGAACTGGAAGCGTTCTCGTCGTCGGTTTCGCATGATCTG
CGCGCGCCGCTGCGCACCATCCAGGGCTACGCCGACCTGCTGGCGACCCGCGTGGATCCGCCGCTCGAAGGCACCCCGCT
GAGCTACGTCGAGCGGATGCGTTCGTCTGCCCGGCGCATGCAGGTACTGATTGAAGATCTGCTGAAGCTGTCGAAGGTGT
CACGGACGGAATTGCATACGCTGCCAGTGCCGCTTGGCCGCATCGCCGCGGACGTCATTGCCAGCCTCCGGAATGTTTCG
CCGCCGCGGGAACATCTACGCATATCGATCGACGAAACGCTGCAGGCCGAAGGCGATCCCGGACTGCTGACGATCGCCCT
CGAAAACCTGCTGTCGAACGCGTGGAAGTACACCGCCAATACGGAAAGTCCCACCATCGAGTTCTTCTCCGAGAAGTTCC
CGGGCAGCGCCACCGTCTTCACCGTGCGCGACAACGGCGTCGGTTTCGACATGGCCCTTGCCGACGAACTCTTCCAGCCT
TTCCACCGCCTCCACCCCGAAGCCGAATTCAGCGGCACCGGCATCGGCCTCACCATCGTCCAGCGCATCATCCACAAGCA
CGGCGGACACATCTGGGCGGAAGCGACACCCGGGGACGGGGCCGTCTTCCGCTTCACGCTGCCGGCCCCCGCATCCCGCT
GCAGCACCGCGTTCGACTGA

Upstream 100 bases:

>100_bases
CGCGAGCCACCGGTTTCTCCCCCTCCGGCACTGTCACCACCGTCGTCTATAGTGCATAAGCGCCCACCGGCGCCCGATCC
CCACCTCCCTGGAGCGGTCG

Downstream 100 bases:

>100_bases
CGCCGCCGCAGCCGGCTGACTACACGGCCGGCACGCCTGCCTCTGCGGACGACAGGTGGATGCCGAAGCCCGAAGCGCCT
GGCGCGAGTTCTGGCTGTAG

Product: putative two-component hybrid sensor and regulator

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MSRLRILHIEDDHDDADLIHHAATRLGVPPDWTMAESRPAFLEALTGRDFDLVLSDSRVPGMDGQEAMRLVRERHPDLPF
VFVSGTDDPLWVEQCFRQGAYDHVSKDQLWRLVPVLQGVGAEAERRRLARLARAHALLVEIVKQLSLARSLDAVVDIVKS
GARQLNGADGATFVLREGDHCHYVAEDAIGPLWQGRRFPLRACISGWAMLEGRAAVVPDIYADERIPADAYRPTFVKSLV
MVPIRAEAPIGAIGNYWAHPHEATPEEVELIQALADSTSLALENLSLYRDLERRVRDRTRRLQAANAELEAFSSSVSHDL
RAPLRTIQGYADLLATRVDPPLEGTPLSYVERMRSSARRMQVLIEDLLKLSKVSRTELHTLPVPLGRIAADVIASLRNVS
PPREHLRISIDETLQAEGDPGLLTIALENLLSNAWKYTANTESPTIEFFSEKFPGSATVFTVRDNGVGFDMALADELFQP
FHRLHPEAEFSGTGIGLTIVQRIIHKHGGHIWAEATPGDGAVFRFTLPAPASRCSTAFD

Sequences:

>Translated_539_residues
MSRLRILHIEDDHDDADLIHHAATRLGVPPDWTMAESRPAFLEALTGRDFDLVLSDSRVPGMDGQEAMRLVRERHPDLPF
VFVSGTDDPLWVEQCFRQGAYDHVSKDQLWRLVPVLQGVGAEAERRRLARLARAHALLVEIVKQLSLARSLDAVVDIVKS
GARQLNGADGATFVLREGDHCHYVAEDAIGPLWQGRRFPLRACISGWAMLEGRAAVVPDIYADERIPADAYRPTFVKSLV
MVPIRAEAPIGAIGNYWAHPHEATPEEVELIQALADSTSLALENLSLYRDLERRVRDRTRRLQAANAELEAFSSSVSHDL
RAPLRTIQGYADLLATRVDPPLEGTPLSYVERMRSSARRMQVLIEDLLKLSKVSRTELHTLPVPLGRIAADVIASLRNVS
PPREHLRISIDETLQAEGDPGLLTIALENLLSNAWKYTANTESPTIEFFSEKFPGSATVFTVRDNGVGFDMALADELFQP
FHRLHPEAEFSGTGIGLTIVQRIIHKHGGHIWAEATPGDGAVFRFTLPAPASRCSTAFD
>Mature_538_residues
SRLRILHIEDDHDDADLIHHAATRLGVPPDWTMAESRPAFLEALTGRDFDLVLSDSRVPGMDGQEAMRLVRERHPDLPFV
FVSGTDDPLWVEQCFRQGAYDHVSKDQLWRLVPVLQGVGAEAERRRLARLARAHALLVEIVKQLSLARSLDAVVDIVKSG
ARQLNGADGATFVLREGDHCHYVAEDAIGPLWQGRRFPLRACISGWAMLEGRAAVVPDIYADERIPADAYRPTFVKSLVM
VPIRAEAPIGAIGNYWAHPHEATPEEVELIQALADSTSLALENLSLYRDLERRVRDRTRRLQAANAELEAFSSSVSHDLR
APLRTIQGYADLLATRVDPPLEGTPLSYVERMRSSARRMQVLIEDLLKLSKVSRTELHTLPVPLGRIAADVIASLRNVSP
PREHLRISIDETLQAEGDPGLLTIALENLLSNAWKYTANTESPTIEFFSEKFPGSATVFTVRDNGVGFDMALADELFQPF
HRLHPEAEFSGTGIGLTIVQRIIHKHGGHIWAEATPGDGAVFRFTLPAPASRCSTAFD

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=30.2521008403361, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=29.1497975708502, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789149, Length=258, Percent_Identity=29.0697674418605, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=291, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=30.6569343065693, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=28.7822878228782, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790346, Length=286, Percent_Identity=28.6713286713287, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=271, Percent_Identity=23.9852398523985, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=304, Percent_Identity=26.9736842105263, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=28.1512605042017, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790861, Length=231, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=28.5067873303167, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59833; Mature: 59701

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLRILHIEDDHDDADLIHHAATRLGVPPDWTMAESRPAFLEALTGRDFDLVLSDSRVP
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCC
GMDGQEAMRLVRERHPDLPFVFVSGTDDPLWVEQCFRQGAYDHVSKDQLWRLVPVLQGVG
CCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
AEAERRRLARLARAHALLVEIVKQLSLARSLDAVVDIVKSGARQLNGADGATFVLREGDH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
CHYVAEDAIGPLWQGRRFPLRACISGWAMLEGRAAVVPDIYADERIPADAYRPTFVKSLV
CEEEHHHHCCHHHCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCHHHHHHHH
MVPIRAEAPIGAIGNYWAHPHEATPEEVELIQALADSTSLALENLSLYRDLERRVRDRTR
HEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQAANAELEAFSSSVSHDLRAPLRTIQGYADLLATRVDPPLEGTPLSYVERMRSSARRM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
QVLIEDLLKLSKVSRTELHTLPVPLGRIAADVIASLRNVSPPREHLRISIDETLQAEGDP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHEEEEECHHHCCCCCC
GLLTIALENLLSNAWKYTANTESPTIEFFSEKFPGSATVFTVRDNGVGFDMALADELFQP
CEEHHHHHHHHHHHHEECCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHH
FHRLHPEAEFSGTGIGLTIVQRIIHKHGGHIWAEATPGDGAVFRFTLPAPASRCSTAFD
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCHHHCCCCCC
>Mature Secondary Structure 
SRLRILHIEDDHDDADLIHHAATRLGVPPDWTMAESRPAFLEALTGRDFDLVLSDSRVP
CCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCC
GMDGQEAMRLVRERHPDLPFVFVSGTDDPLWVEQCFRQGAYDHVSKDQLWRLVPVLQGVG
CCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
AEAERRRLARLARAHALLVEIVKQLSLARSLDAVVDIVKSGARQLNGADGATFVLREGDH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
CHYVAEDAIGPLWQGRRFPLRACISGWAMLEGRAAVVPDIYADERIPADAYRPTFVKSLV
CEEEHHHHCCHHHCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCHHHHHHHH
MVPIRAEAPIGAIGNYWAHPHEATPEEVELIQALADSTSLALENLSLYRDLERRVRDRTR
HEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQAANAELEAFSSSVSHDLRAPLRTIQGYADLLATRVDPPLEGTPLSYVERMRSSARRM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
QVLIEDLLKLSKVSRTELHTLPVPLGRIAADVIASLRNVSPPREHLRISIDETLQAEGDP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHEEEEECHHHCCCCCC
GLLTIALENLLSNAWKYTANTESPTIEFFSEKFPGSATVFTVRDNGVGFDMALADELFQP
CEEHHHHHHHHHHHHEECCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHH
FHRLHPEAEFSGTGIGLTIVQRIIHKHGGHIWAEATPGDGAVFRFTLPAPASRCSTAFD
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]