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The map label for this gene is nahR [H]

Identifier: 119897873

GI number: 119897873

Start: 1740086

End: 1740970

Strand: Reverse

Name: nahR [H]

Synonym: azo1582

Alternate gene names: 119897873

Gene position: 1740970-1740086 (Counterclockwise)

Preceding gene: 119897875

Following gene: 119897870

Centisome position: 39.78

GC content: 66.1

Gene sequence:

>885_bases
TTGCGACGTCTCGACCTCAATCTGCTGGTAACGCTGGACGCATTGCTGACCGAACTGAACGTCACGCGTGCAGCCGAGCG
CCTGCATCTGTCACAACCGACGGTCAGCGTCCAGCTTGCCAAGCTGCGTGAGATGTTCGGAGATCCGCTGTTGCTGCCGG
GCCCGCGCGGCGTGCGCCCAACCGCCCGCGCCGACGCGCTGCGCGAGCCGCTGCAAGACGCACTCAAAGCACTCGAGCGG
GCTGTGGCGCCCGCTTCCCCATTCGATCCGGGTCTGGCACGCCAGAACTGGCGCGTGGCGGCCACCGACTATGGCGCATC
GACAATCCTCCTGCCGGCGCTGACTACGCTGCGGGCCGCAGCCCCCAACACCCGCTTGGCTGTTGTGGAACTGCAACCCG
CCACCCTGGTGCAACGGTCGGAACGCGGGGACATCGATCTCGCGTTCCACATCAGCTCGGAAGCCCCTCCCGGCCTGCAC
CAGCGGCTGTTGTTCGCCGAGCGTTACGTGCTCGCCGGCCGAGTCGGACACCCGCGCTTGACTGTTCGCCCCACCCTTGC
CGAATTCTGCGAACTCGAACACGTAATCGTATCGCCCAACGGCGGTGGATTTCACGGCGTCACCGACACTGCCCTTGCTG
CACTCGGAATGACACGAAAGGTCGCGCTCTCGGTGCCGCACTTCCTCTTCCTCAGCGCCACCCTCGCCCGCACCGACCTG
GTGGCGATGGTCCCGTCGCGGCTGGTCCGCTACAACACCGCGTTACAGGTCGTGGATACGCCACTGGAACTGCCCGGCTT
CCAGATGGTGATGCTGTGGCACGAACGCGTTCACCGCGATCCGGCGCACCAGTGGTTGCGGGAGCAGATTGCCGGCGCCG
TCTGA

Upstream 100 bases:

>100_bases
TCATGGCGGAGGCTCCGTAATAGACCGCCGCAGGATAGGGTTGCGTGAGATATAGTTGAAATGAATTTCCGGAATCTCTG
GTATTGCCTTGGATAATTCC

Downstream 100 bases:

>100_bases
AATCAGCCGGCCCCGTCTGCCACACGGCGAGCGCGTGAGCACCAACAAAAAAGCCTGACGTTTTCAGGCGTCAGGCTTTA
TCGGTCACTCCCACTCGATT

Product: HTH-type transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MRRLDLNLLVTLDALLTELNVTRAAERLHLSQPTVSVQLAKLREMFGDPLLLPGPRGVRPTARADALREPLQDALKALER
AVAPASPFDPGLARQNWRVAATDYGASTILLPALTTLRAAAPNTRLAVVELQPATLVQRSERGDIDLAFHISSEAPPGLH
QRLLFAERYVLAGRVGHPRLTVRPTLAEFCELEHVIVSPNGGGFHGVTDTALAALGMTRKVALSVPHFLFLSATLARTDL
VAMVPSRLVRYNTALQVVDTPLELPGFQMVMLWHERVHRDPAHQWLREQIAGAV

Sequences:

>Translated_294_residues
MRRLDLNLLVTLDALLTELNVTRAAERLHLSQPTVSVQLAKLREMFGDPLLLPGPRGVRPTARADALREPLQDALKALER
AVAPASPFDPGLARQNWRVAATDYGASTILLPALTTLRAAAPNTRLAVVELQPATLVQRSERGDIDLAFHISSEAPPGLH
QRLLFAERYVLAGRVGHPRLTVRPTLAEFCELEHVIVSPNGGGFHGVTDTALAALGMTRKVALSVPHFLFLSATLARTDL
VAMVPSRLVRYNTALQVVDTPLELPGFQMVMLWHERVHRDPAHQWLREQIAGAV
>Mature_294_residues
MRRLDLNLLVTLDALLTELNVTRAAERLHLSQPTVSVQLAKLREMFGDPLLLPGPRGVRPTARADALREPLQDALKALER
AVAPASPFDPGLARQNWRVAATDYGASTILLPALTTLRAAAPNTRLAVVELQPATLVQRSERGDIDLAFHISSEAPPGLH
QRLLFAERYVLAGRVGHPRLTVRPTLAEFCELEHVIVSPNGGGFHGVTDTALAALGMTRKVALSVPHFLFLSATLARTDL
VAMVPSRLVRYNTALQVVDTPLELPGFQMVMLWHERVHRDPAHQWLREQIAGAV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=306, Percent_Identity=29.0849673202614, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081766, Length=255, Percent_Identity=26.2745098039216, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788887, Length=269, Percent_Identity=28.2527881040892, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32243; Mature: 32243

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLDLNLLVTLDALLTELNVTRAAERLHLSQPTVSVQLAKLREMFGDPLLLPGPRGVRP
CCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCC
TARADALREPLQDALKALERAVAPASPFDPGLARQNWRVAATDYGASTILLPALTTLRAA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHC
APNTRLAVVELQPATLVQRSERGDIDLAFHISSEAPPGLHQRLLFAERYVLAGRVGHPRL
CCCCEEEEEEECCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCE
TVRPTLAEFCELEHVIVSPNGGGFHGVTDTALAALGMTRKVALSVPHFLFLSATLARTDL
EECHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
VAMVPSRLVRYNTALQVVDTPLELPGFQMVMLWHERVHRDPAHQWLREQIAGAV
HHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRLDLNLLVTLDALLTELNVTRAAERLHLSQPTVSVQLAKLREMFGDPLLLPGPRGVRP
CCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCC
TARADALREPLQDALKALERAVAPASPFDPGLARQNWRVAATDYGASTILLPALTTLRAA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHC
APNTRLAVVELQPATLVQRSERGDIDLAFHISSEAPPGLHQRLLFAERYVLAGRVGHPRL
CCCCEEEEEEECCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCE
TVRPTLAEFCELEHVIVSPNGGGFHGVTDTALAALGMTRKVALSVPHFLFLSATLARTDL
EECHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
VAMVPSRLVRYNTALQVVDTPLELPGFQMVMLWHERVHRDPAHQWLREQIAGAV
HHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]