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The map label for this gene is gst [H]

Identifier: 119897832

GI number: 119897832

Start: 1688741

End: 1689355

Strand: Direct

Name: gst [H]

Synonym: azo1541

Alternate gene names: 119897832

Gene position: 1688741-1689355 (Clockwise)

Preceding gene: 119897831

Following gene: 119897834

Centisome position: 38.59

GC content: 64.39

Gene sequence:

>615_bases
ATGAAGTTCTACATGACGCCCGGTTCGTGTTCGACCGGCATCCACATCCTCCTCGAGGAAATCGGCAAGGTCTTCGAGGC
CTACATCGTCAATCTTCCGGCCGGCGACCACAAAAAGCCGGACTACGTGGCGATGAACCCGAAATCCACGATTCCGGTGC
TGGTGCGCGACGACGGCAGCGTGCTGACCGAATTTCCCGCGATCGCGTTCTGGCTGGCGCGGGCCAATCCGCGCGCGCGG
CTGGTGCCGGACGATGACGAGGGCGTGGCGCGGGTGCTCGAGCACCTGTGCTACATCACCGCGACCATCCACGGCCAGGG
CTATACCCGCATCTTCACCACCGATGCCTATACCGACAACCCGGCCGAGCACGATGCCGTGAAGGCGCGCGGACGGGAGA
TCGTCGATGCCGGTTTCGCGGTGATGGAGATTGCGCTGGCGGGCAGGGACTATCTCGTCGGCAACTTCTCGATTGCCGAC
GCGGCGCTGTTCTACGTCAGTTTCTGGGCCGACCGCATCGGCATACCGCTGCCGCCCAACTGCGCCGCCCACTATCAGCG
AATGCGGGCGCGGCCCGTGGTGCAGCAGGTGCTGCGTGAAGAGGGCTATCGCTGA

Upstream 100 bases:

>100_bases
TGCCGCGCATCGAACGGAACGGAGCTTGCTTCGCGGGGTGGCGGGCGCACTTTGTGTGCGCTTTGCGACACCCCAGCCAT
CCCGCGGAGCCGCCCCTTCC

Downstream 100 bases:

>100_bases
GCGCGACTGGCGACGGTTCAGCCCGTCTGAACCTGCGGAATGCGCCGCAGCCACAGTGCCAGCGCCAGCGTGAGCAATGC
ACCCAGCCCTAGCAGCAGTA

Product: putative glutathione transferase

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKFYMTPGSCSTGIHILLEEIGKVFEAYIVNLPAGDHKKPDYVAMNPKSTIPVLVRDDGSVLTEFPAIAFWLARANPRAR
LVPDDDEGVARVLEHLCYITATIHGQGYTRIFTTDAYTDNPAEHDAVKARGREIVDAGFAVMEIALAGRDYLVGNFSIAD
AALFYVSFWADRIGIPLPPNCAAHYQRMRARPVVQQVLREEGYR

Sequences:

>Translated_204_residues
MKFYMTPGSCSTGIHILLEEIGKVFEAYIVNLPAGDHKKPDYVAMNPKSTIPVLVRDDGSVLTEFPAIAFWLARANPRAR
LVPDDDEGVARVLEHLCYITATIHGQGYTRIFTTDAYTDNPAEHDAVKARGREIVDAGFAVMEIALAGRDYLVGNFSIAD
AALFYVSFWADRIGIPLPPNCAAHYQRMRARPVVQQVLREEGYR
>Mature_204_residues
MKFYMTPGSCSTGIHILLEEIGKVFEAYIVNLPAGDHKKPDYVAMNPKSTIPVLVRDDGSVLTEFPAIAFWLARANPRAR
LVPDDDEGVARVLEHLCYITATIHGQGYTRIFTTDAYTDNPAEHDAVKARGREIVDAGFAVMEIALAGRDYLVGNFSIAD
AALFYVSFWADRIGIPLPPNCAAHYQRMRARPVVQQVLREEGYR

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=213, Percent_Identity=36.6197183098592, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI85725204, Length=165, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17737923, Length=165, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22701; Mature: 22701

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFYMTPGSCSTGIHILLEEIGKVFEAYIVNLPAGDHKKPDYVAMNPKSTIPVLVRDDGS
CEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCEEEEECCCC
VLTEFPAIAFWLARANPRARLVPDDDEGVARVLEHLCYITATIHGQGYTRIFTTDAYTDN
HHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCC
PAEHDAVKARGREIVDAGFAVMEIALAGRDYLVGNFSIADAALFYVSFWADRIGIPLPPN
CCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCC
CAAHYQRMRARPVVQQVLREEGYR
HHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKFYMTPGSCSTGIHILLEEIGKVFEAYIVNLPAGDHKKPDYVAMNPKSTIPVLVRDDGS
CEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCEEEEECCCC
VLTEFPAIAFWLARANPRARLVPDDDEGVARVLEHLCYITATIHGQGYTRIFTTDAYTDN
HHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCC
PAEHDAVKARGREIVDAGFAVMEIALAGRDYLVGNFSIADAALFYVSFWADRIGIPLPPN
CCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCC
CAAHYQRMRARPVVQQVLREEGYR
HHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]