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The map label for this gene is orn

Identifier: 119897809

GI number: 119897809

Start: 1663104

End: 1663652

Strand: Direct

Name: orn

Synonym: azo1518

Alternate gene names: 119897809

Gene position: 1663104-1663652 (Clockwise)

Preceding gene: 119897806

Following gene: 119897813

Centisome position: 38.0

GC content: 63.93

Gene sequence:

>549_bases
ATGGCACAGGACCCCAACCACCTGATATGGCTCGACATGGAGATGACCGGGCTGGAGCCCGACCGCGACCGCATCATCGA
GATCGCGCTGGTCATCACCGATAGTCAGCTCAACACGATCGCGGAAGCGCCGGTCATCGCGGTGCATCAGCCGGAATCCG
TCCTGGACGCGATGGACGACTGGAACAAGAACACCCACGGCAAATCGGGCCTGATCGACCGGGTGCGGGCGTCGACCGTG
TCCGAGGCCGAGGCCGAGGCGCGGATGCTGGCCTTCCTGCAGGAGTGGGTGCCGGCGCGTACCTCGCCGATGTGCGGCAA
CTCGATCTGTCAGGATCGTCGCTTCCTGGCGCGGTACATGCCGGCTTTCGAAGCGTGGTTCCACTACCGCAACCTGGATG
TTTCGACGCTGAAGGAGCTTGCGAAGCGCTGGCGTCCGGAGGTGTACAAGGGCGTGGACAAGAAGGGCAAGCACGAGGCG
CTCGCCGACATCCACGAGTCGATCGGCGAACTCCGCCACTACCGCGACAATTTCCTGCGGCTTGCCTGA

Upstream 100 bases:

>100_bases
GTGGATGGCGAGGCCCGCGGGGCGGGCTGCCGCTGCGGTTCTGTGACACAATCCGCCCCTTCATTGTTTCGCTGAAAATC
GCTGAAAAGGCCGAAAGATT

Downstream 100 bases:

>100_bases
CCTCTCCCGCTGTCGAACCACCCTCAGCGGGCGCGGTTCGAGGCCCTGATGGCCGCTGCGGCGGCCATCAGGCCGGCGGT
CGAAGCATCGCACTCGGCGC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MAQDPNHLIWLDMEMTGLEPDRDRIIEIALVITDSQLNTIAEAPVIAVHQPESVLDAMDDWNKNTHGKSGLIDRVRASTV
SEAEAEARMLAFLQEWVPARTSPMCGNSICQDRRFLARYMPAFEAWFHYRNLDVSTLKELAKRWRPEVYKGVDKKGKHEA
LADIHESIGELRHYRDNFLRLA

Sequences:

>Translated_182_residues
MAQDPNHLIWLDMEMTGLEPDRDRIIEIALVITDSQLNTIAEAPVIAVHQPESVLDAMDDWNKNTHGKSGLIDRVRASTV
SEAEAEARMLAFLQEWVPARTSPMCGNSICQDRRFLARYMPAFEAWFHYRNLDVSTLKELAKRWRPEVYKGVDKKGKHEA
LADIHESIGELRHYRDNFLRLA
>Mature_181_residues
AQDPNHLIWLDMEMTGLEPDRDRIIEIALVITDSQLNTIAEAPVIAVHQPESVLDAMDDWNKNTHGKSGLIDRVRASTVS
EAEAEARMLAFLQEWVPARTSPMCGNSICQDRRFLARYMPAFEAWFHYRNLDVSTLKELAKRWRPEVYKGVDKKGKHEAL
ADIHESIGELRHYRDNFLRLA

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=180, Percent_Identity=48.3333333333333, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=60.2209944751381, Blast_Score=243, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17557752, Length=172, Percent_Identity=46.5116279069767, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=201, Percent_Identity=36.318407960199, Blast_Score=118, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21355135, Length=174, Percent_Identity=44.2528735632184, Blast_Score=173, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_AZOSB (A1K5N0)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_933022.1
- ProteinModelPortal:   A1K5N0
- SMR:   A1K5N0
- STRING:   A1K5N0
- GeneID:   4606894
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo1518
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   A1K5N0
- ProtClustDB:   PRK05359
- BioCyc:   ASP62928:AZO1518-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20956; Mature: 20825

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDPNHLIWLDMEMTGLEPDRDRIIEIALVITDSQLNTIAEAPVIAVHQPESVLDAMDD
CCCCCCCEEEEEEEECCCCCCHHHEEEEEEEEECCHHHHHHHCCEEEEECCHHHHHHHHH
WNKNTHGKSGLIDRVRASTVSEAEAEARMLAFLQEWVPARTSPMCGNSICQDRRFLARYM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
PAFEAWFHYRNLDVSTLKELAKRWRPEVYKGVDKKGKHEALADIHESIGELRHYRDNFLR
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LA
CC
>Mature Secondary Structure 
AQDPNHLIWLDMEMTGLEPDRDRIIEIALVITDSQLNTIAEAPVIAVHQPESVLDAMDD
CCCCCCEEEEEEEECCCCCCHHHEEEEEEEEECCHHHHHHHCCEEEEECCHHHHHHHHH
WNKNTHGKSGLIDRVRASTVSEAEAEARMLAFLQEWVPARTSPMCGNSICQDRRFLARYM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
PAFEAWFHYRNLDVSTLKELAKRWRPEVYKGVDKKGKHEALADIHESIGELRHYRDNFLR
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA