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The map label for this gene is tsr [H]

Identifier: 119897744

GI number: 119897744

Start: 1582905

End: 1584779

Strand: Direct

Name: tsr [H]

Synonym: azo1453

Alternate gene names: 119897744

Gene position: 1582905-1584779 (Clockwise)

Preceding gene: 119897743

Following gene: 119897745

Centisome position: 36.17

GC content: 71.68

Gene sequence:

>1875_bases
ATGAGACCCACCTACGTCAGTGCCCCGGTCGTGCCCGGTCCGTTCGAACGCCTGCCGATCGCGGGCAAGCTGTTGCTGGT
GGCGATGCTGCCCGCGTGCGGCGCGCTCGGCCTGCTGTTCAGCCCGGCCGAAAGCGGCGGGCGCGGGGCGGTGATGGCGC
TGTCCGCCTTGCTCATCCTCGCCGGCTTCGCACTCGCGCTGTGGCTGGCGGTCTACCTCGAGCGCCGGATGCAGCGCCTG
GCGGCGCGGGTACGCGGCTTCGCCGAGGGCGAACTCAACGCGCGGCCGCGCGAAATCGGCGACGGCGACGCGCTTACCGC
GCTGTGGCAGGGGATCGAACGCAGCCTCGGAACGCTGAGCGAGCGCTTCTCCGCCAGCGCCGCCGAAGCGGACTACAACC
GTCTGATCCGCGAGGCGCTGGATACGGCCGCGACGAGCGTGATGATTGCGGATACCGGCGGCACCATCGTCTATATGAAT
GCCGCCGGCCTGCGCCTGCTGGAGCGGGTGCAGATGGAAATGGGCGGCGCCCTGCCCGGCGGGGTCAGGGCGGACCAGAT
CGTCGGCAGCAGCTTCGATGTGTTCCACCGCCAGCCCGAAGTGCAGCGCCAGCGCATCGCGGCGATGGTCGGCACCCATT
CGGCGGAAATCCGCCTCGGCGCCCGTTCGCTGCGCCAGCAGGCCACCCCGGTGTTCGATGCGGACGGCTTGCGCGCCGGC
ACCGTCGTGGAGTGGAGCGACATCACCGCCGAAGTGGGCGTGCGCGCCGAACTCGCCGGCTTGGTGGAAGCGGCGGCGGC
GGGGGACTTCAGCCGTCGGCTGCCGGTGGAGAACAAGAGCGGCTTCTTCCTGCAGCTGGCCGAAGGGCTGAACCGGCTGA
TGGGGGAGATTTCGGGCAGCGTGGATGCGGTGGCGCGGGTGCTGAACGCGGTGGCGCGCGGCGACCTGACCGAGCGGATC
GAGGGCGAGTACCGGGGCACCTTCGGGCAGTTGCAGCACGACGCGAACGCGACGGTGCTCAGGCTGCGCGAAGTGGTGGG
CCGCATCCAGGATTCGGCGGTGGCGATCAACCGCGCGGCGCGCGAGATTGCGGCGGGCAACGGGGAGCTGTCGACGCGCA
CCGAGCAGCAGGCGAGCGCGCTCGAAGAGACGGCGAGTTCGATGGAGGAGCTGTCGGCGACGGTTCGCCAGACCGCGGAC
AACGCACGCGCGGCCAACGGGCTGGCGCTGGGCGCGCATGCGGTGGCCGGCCGTGGCGGCGAGGCGATGCGGCGGGTGGT
GAGCACGATGGGCGAGATCGAGCACTCGGCACGCAAGATCGGCGACATCGTGGGCGTGATCGACGCGCTGGCGTTCCAGA
CCAACATCCTCGCGCTCAACGCGGCGGTGGAGGCGGCGCGGGCGGGCGAGCAGGGCCGCGGCTTTGCGGTGGTGGCGGCC
GAGGTGCGCAGCCTCGCGCAGCGCAGCGCGCAGTCGGCGCGCGAGGTGAAGGCGCTGATCGGCGAATCGGTGGAGCGGGT
CGAGCACGGCGTGAAGCTGGTCGATGACGCGGGCCGCACGGTGGATGAAGTGGTGTCGGCCTTTGGCCAGGTGGCCACGC
TGATGAGCGAGATCGCGGGCGCGAGCGGCGAGCAGAGCGCCGGCATCGGCCAGGTGTGCATGGCGGTGGGACAGATGGAC
GAGATGACGCAGCACAACGCGGCGTTGGTGGAAGAGGCGGCCGCGGCGGCGATCAGCCTGGAAGAGCAGGCGCGCGAACT
GGTGGACGTGGTCGGCGTGTTCCGTATCGGCGAAGCGGCGCCCGCGCTGCGCGTGCTGCCGCGCGGGACTGGCGTGCGGG
GTGGCGGAGCGCGCGGCCGTGGAGGACAGCCATGA

Upstream 100 bases:

>100_bases
TGGGCGCCGCGGGGGACGCGATGCTGGTCGTGCTCGATGTTGAACGCCTGATGGCCGCGCCCGAACTGGCGCTGGTCGAC
CCTGACCCGGAAGCCCAGTC

Downstream 100 bases:

>100_bases
AAACCGCGGACGTGACCCAGCGCGAGATCGAGGTCCTGCCGCACCAGTCGCTGGTGTCCAAGACCGATCTGGACGGTCGC
ATCACCTATGCGAGCCCGGA

Product: putative serine chemoreceptor protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MRPTYVSAPVVPGPFERLPIAGKLLLVAMLPACGALGLLFSPAESGGRGAVMALSALLILAGFALALWLAVYLERRMQRL
AARVRGFAEGELNARPREIGDGDALTALWQGIERSLGTLSERFSASAAEADYNRLIREALDTAATSVMIADTGGTIVYMN
AAGLRLLERVQMEMGGALPGGVRADQIVGSSFDVFHRQPEVQRQRIAAMVGTHSAEIRLGARSLRQQATPVFDADGLRAG
TVVEWSDITAEVGVRAELAGLVEAAAAGDFSRRLPVENKSGFFLQLAEGLNRLMGEISGSVDAVARVLNAVARGDLTERI
EGEYRGTFGQLQHDANATVLRLREVVGRIQDSAVAINRAAREIAAGNGELSTRTEQQASALEETASSMEELSATVRQTAD
NARAANGLALGAHAVAGRGGEAMRRVVSTMGEIEHSARKIGDIVGVIDALAFQTNILALNAAVEAARAGEQGRGFAVVAA
EVRSLAQRSAQSAREVKALIGESVERVEHGVKLVDDAGRTVDEVVSAFGQVATLMSEIAGASGEQSAGIGQVCMAVGQMD
EMTQHNAALVEEAAAAAISLEEQARELVDVVGVFRIGEAAPALRVLPRGTGVRGGGARGRGGQP

Sequences:

>Translated_624_residues
MRPTYVSAPVVPGPFERLPIAGKLLLVAMLPACGALGLLFSPAESGGRGAVMALSALLILAGFALALWLAVYLERRMQRL
AARVRGFAEGELNARPREIGDGDALTALWQGIERSLGTLSERFSASAAEADYNRLIREALDTAATSVMIADTGGTIVYMN
AAGLRLLERVQMEMGGALPGGVRADQIVGSSFDVFHRQPEVQRQRIAAMVGTHSAEIRLGARSLRQQATPVFDADGLRAG
TVVEWSDITAEVGVRAELAGLVEAAAAGDFSRRLPVENKSGFFLQLAEGLNRLMGEISGSVDAVARVLNAVARGDLTERI
EGEYRGTFGQLQHDANATVLRLREVVGRIQDSAVAINRAAREIAAGNGELSTRTEQQASALEETASSMEELSATVRQTAD
NARAANGLALGAHAVAGRGGEAMRRVVSTMGEIEHSARKIGDIVGVIDALAFQTNILALNAAVEAARAGEQGRGFAVVAA
EVRSLAQRSAQSAREVKALIGESVERVEHGVKLVDDAGRTVDEVVSAFGQVATLMSEIAGASGEQSAGIGQVCMAVGQMD
EMTQHNAALVEEAAAAAISLEEQARELVDVVGVFRIGEAAPALRVLPRGTGVRGGGARGRGGQP
>Mature_624_residues
MRPTYVSAPVVPGPFERLPIAGKLLLVAMLPACGALGLLFSPAESGGRGAVMALSALLILAGFALALWLAVYLERRMQRL
AARVRGFAEGELNARPREIGDGDALTALWQGIERSLGTLSERFSASAAEADYNRLIREALDTAATSVMIADTGGTIVYMN
AAGLRLLERVQMEMGGALPGGVRADQIVGSSFDVFHRQPEVQRQRIAAMVGTHSAEIRLGARSLRQQATPVFDADGLRAG
TVVEWSDITAEVGVRAELAGLVEAAAAGDFSRRLPVENKSGFFLQLAEGLNRLMGEISGSVDAVARVLNAVARGDLTERI
EGEYRGTFGQLQHDANATVLRLREVVGRIQDSAVAINRAAREIAAGNGELSTRTEQQASALEETASSMEELSATVRQTAD
NARAANGLALGAHAVAGRGGEAMRRVVSTMGEIEHSARKIGDIVGVIDALAFQTNILALNAAVEAARAGEQGRGFAVVAA
EVRSLAQRSAQSAREVKALIGESVERVEHGVKLVDDAGRTVDEVVSAFGQVATLMSEIAGASGEQSAGIGQVCMAVGQMD
EMTQHNAALVEEAAAAAISLEEQARELVDVVGVFRIGEAAPALRVLPRGTGVRGGGARGRGGQP

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=307, Percent_Identity=51.7915309446254, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788195, Length=291, Percent_Identity=55.6701030927835, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI2367378, Length=288, Percent_Identity=58.3333333333333, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1788194, Length=237, Percent_Identity=59.915611814346, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789453, Length=256, Percent_Identity=40.234375, Blast_Score=192, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 65304; Mature: 65304

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTYVSAPVVPGPFERLPIAGKLLLVAMLPACGALGLLFSPAESGGRGAVMALSALLIL
CCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AGFALALWLAVYLERRMQRLAARVRGFAEGELNARPREIGDGDALTALWQGIERSLGTLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERFSASAAEADYNRLIREALDTAATSVMIADTGGTIVYMNAAGLRLLERVQMEMGGALPG
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCC
GVRADQIVGSSFDVFHRQPEVQRQRIAAMVGTHSAEIRLGARSLRQQATPVFDADGLRAG
CCCHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCCCCCCCCCC
TVVEWSDITAEVGVRAELAGLVEAAAAGDFSRRLPVENKSGFFLQLAEGLNRLMGEISGS
CEEEHHHHHHHHCHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
VDAVARVLNAVARGDLTERIEGEYRGTFGQLQHDANATVLRLREVVGRIQDSAVAINRAA
HHHHHHHHHHHHHCCHHHHHCCHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REIAAGNGELSTRTEQQASALEETASSMEELSATVRQTADNARAANGLALGAHAVAGRGG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHCCCH
EAMRRVVSTMGEIEHSARKIGDIVGVIDALAFQTNILALNAAVEAARAGEQGRGFAVVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHH
EVRSLAQRSAQSAREVKALIGESVERVEHGVKLVDDAGRTVDEVVSAFGQVATLMSEIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
ASGEQSAGIGQVCMAVGQMDEMTQHNAALVEEAAAAAISLEEQARELVDVVGVFRIGEAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PALRVLPRGTGVRGGGARGRGGQP
CHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPTYVSAPVVPGPFERLPIAGKLLLVAMLPACGALGLLFSPAESGGRGAVMALSALLIL
CCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AGFALALWLAVYLERRMQRLAARVRGFAEGELNARPREIGDGDALTALWQGIERSLGTLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERFSASAAEADYNRLIREALDTAATSVMIADTGGTIVYMNAAGLRLLERVQMEMGGALPG
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCC
GVRADQIVGSSFDVFHRQPEVQRQRIAAMVGTHSAEIRLGARSLRQQATPVFDADGLRAG
CCCHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCCCCCCCCCC
TVVEWSDITAEVGVRAELAGLVEAAAAGDFSRRLPVENKSGFFLQLAEGLNRLMGEISGS
CEEEHHHHHHHHCHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
VDAVARVLNAVARGDLTERIEGEYRGTFGQLQHDANATVLRLREVVGRIQDSAVAINRAA
HHHHHHHHHHHHHCCHHHHHCCHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REIAAGNGELSTRTEQQASALEETASSMEELSATVRQTADNARAANGLALGAHAVAGRGG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHCCCH
EAMRRVVSTMGEIEHSARKIGDIVGVIDALAFQTNILALNAAVEAARAGEQGRGFAVVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHH
EVRSLAQRSAQSAREVKALIGESVERVEHGVKLVDDAGRTVDEVVSAFGQVATLMSEIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
ASGEQSAGIGQVCMAVGQMDEMTQHNAALVEEAAAAAISLEEQARELVDVVGVFRIGEAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PALRVLPRGTGVRGGGARGRGGQP
CHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]