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The map label for this gene is cheW2 [H]

Identifier: 119897743

GI number: 119897743

Start: 1582399

End: 1582908

Strand: Direct

Name: cheW2 [H]

Synonym: azo1452

Alternate gene names: 119897743

Gene position: 1582399-1582908 (Clockwise)

Preceding gene: 119897742

Following gene: 119897744

Centisome position: 36.16

GC content: 71.76

Gene sequence:

>510_bases
ATGTCAGCCCCTGACCGACCGGCGCTGGCGCCGGCGGAAGCCGCAGCCGAGGCCGGCGAGTTCCTCACCTTCACGCTCGG
CGGCGAGCTGTACGCGATCGACATCCTGAAGGTGCGGGAGATCCGCGCGTGGGAGCGGGTGACGCGGATCGCGGGGGCGC
CGGCCTTCCTCAAGGGCGTCATGAACCTGCGCGGCGCGATCGTGCCGGTGGTGGATCTGCGTCTGTACTTCGGCTGTGGC
GACGGCGCCTGCGGCCCGTTCACCGTGATGATCGTGCTGCAACTCGCCGGGCGCCTGGCCGCGGTGGTGGTCGATGCGGT
GGCCGACGTGGTGCGCCTGGCCGCGGGCGAAATCCAGCCCGCGCCGGAGTTCGCCGGCCTGGTCGGCGGACGCTATATCC
GCGGCCTGGGCGCCGCGGGGGACGCGATGCTGGTCGTGCTCGATGTTGAACGCCTGATGGCCGCGCCCGAACTGGCGCTG
GTCGACCCTGACCCGGAAGCCCAGTCATGA

Upstream 100 bases:

>100_bases
GATCGGCACCGCGCGCGACAGCGCGGCGATCTGATGGCGCGGCGCTACAGATTGACCGCCGGCGGCCGTAGACCGATCAA
AGCAATCAAGGAGTCCGAAC

Downstream 100 bases:

>100_bases
GACCCACCTACGTCAGTGCCCCGGTCGTGCCCGGTCCGTTCGAACGCCTGCCGATCGCGGGCAAGCTGTTGCTGGTGGCG
ATGCTGCCCGCGTGCGGCGC

Product: positive regulator of CheA protein activity

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSAPDRPALAPAEAAAEAGEFLTFTLGGELYAIDILKVREIRAWERVTRIAGAPAFLKGVMNLRGAIVPVVDLRLYFGCG
DGACGPFTVMIVLQLAGRLAAVVVDAVADVVRLAAGEIQPAPEFAGLVGGRYIRGLGAAGDAMLVVLDVERLMAAPELAL
VDPDPEAQS

Sequences:

>Translated_169_residues
MSAPDRPALAPAEAAAEAGEFLTFTLGGELYAIDILKVREIRAWERVTRIAGAPAFLKGVMNLRGAIVPVVDLRLYFGCG
DGACGPFTVMIVLQLAGRLAAVVVDAVADVVRLAAGEIQPAPEFAGLVGGRYIRGLGAAGDAMLVVLDVERLMAAPELAL
VDPDPEAQS
>Mature_168_residues
SAPDRPALAPAEAAAEAGEFLTFTLGGELYAIDILKVREIRAWERVTRIAGAPAFLKGVMNLRGAIVPVVDLRLYFGCGD
GACGPFTVMIVLQLAGRLAAVVVDAVADVVRLAAGEIQPAPEFAGLVGGRYIRGLGAAGDAMLVVLDVERLMAAPELALV
DPDPEAQS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=144, Percent_Identity=54.8611111111111, Blast_Score=163, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17569; Mature: 17438

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPDRPALAPAEAAAEAGEFLTFTLGGELYAIDILKVREIRAWERVTRIAGAPAFLKGV
CCCCCCCCCCCHHHHHCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHH
MNLRGAIVPVVDLRLYFGCGDGACGPFTVMIVLQLAGRLAAVVVDAVADVVRLAAGEIQP
HHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
APEFAGLVGGRYIRGLGAAGDAMLVVLDVERLMAAPELALVDPDPEAQS
CHHHHHHHCCHHHHCCCCCCCEEEEEEEHHHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SAPDRPALAPAEAAAEAGEFLTFTLGGELYAIDILKVREIRAWERVTRIAGAPAFLKGV
CCCCCCCCCCHHHHHCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHH
MNLRGAIVPVVDLRLYFGCGDGACGPFTVMIVLQLAGRLAAVVVDAVADVVRLAAGEIQP
HHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
APEFAGLVGGRYIRGLGAAGDAMLVVLDVERLMAAPELALVDPDPEAQS
CHHHHHHHCCHHHHCCCCCCCEEEEEEEHHHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]