Click here to switch to the map view.

The map label for this gene is hoxU [H]

Identifier: 119897704

GI number: 119897704

Start: 1545286

End: 1545990

Strand: Direct

Name: hoxU [H]

Synonym: azo1413

Alternate gene names: 119897704

Gene position: 1545286-1545990 (Clockwise)

Preceding gene: 119897703

Following gene: 119897705

Centisome position: 35.31

GC content: 66.24

Gene sequence:

>705_bases
ATGAAACGCCAGTTCCTGTTCGACGGCCGTCCGGTGCCATTCGACGAGGGCCAGACCATCCTGCAGGCGGCGCGCGCCGC
CGGCCACTACATCCCGCATCTGTGCTGGCACCCGGACTTTCCGCCGCACGGTTCCTGCAAGCTGTGCACCGTGAAGGTGG
GCGGGCGGCATGTGTCCTCGTGCGCATTTCCGGCACGCGAGGGCATGGAGGTCGAAAGCGATACGCCGGAGATCAATGCC
GAGCGCCGCGCGCTGCTGCAGATGCTGTTCGTGGAGGGCAACCACTTCTGTCCCGGGTGCGAGAAGAGCGGCAACTGCCA
GTTGCAGGCGCTGGCCTACGATCTCGAGATGACCACGCCGCGCTTCCCCCATTTCTATCCGGATCGCCCGGTCGATGCCT
CGCACCCCGACGTGCTGCTCGATTTCAACCGTTGCATTTTCTGCGAGTTGTGCGTGCGGGCCAGCCGCGAGGTCGACGGC
AAGAACGTGTTTGCGCTCGGCGGCCGCGGGTTGGGCAAGCACCTGGTCGTCAATGCCGAAACCGGCCGGCTGGCCGACAC
CACGCTGGCCGCCGACGACCTTGCCGCCAACATCTGCCCGGTCGGCGTGATCCTCAAGAAGCGCGTCGGGTTCGCGGTGC
CGATCGGCGAACGGACCTACGACGCCGAGCCGATCCACGTGCATGCCATGGAGCGCGACACATGA

Upstream 100 bases:

>100_bases
CGGCCTTCGATCTCGATCAGGCCTTGGCGCCGGCGCGCCGCGTCAGCGGCCGCGACGATGCGGCTGCCCACCTCGCCGCC
CGCGCAACCGGAGACGCATC

Downstream 100 bases:

>100_bases
CCGAGCCGTCCGCGCAGGAGAAGCGGCCCGAACCGGCCCGCTTGCGCATCGCCACCGCGTCGCTGGCGGGCTGCTTCGGC
TGCCACATGTCGCTGCTCGA

Product: hydrogen dehydrogenase subunit gamma

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKRQFLFDGRPVPFDEGQTILQAARAAGHYIPHLCWHPDFPPHGSCKLCTVKVGGRHVSSCAFPAREGMEVESDTPEINA
ERRALLQMLFVEGNHFCPGCEKSGNCQLQALAYDLEMTTPRFPHFYPDRPVDASHPDVLLDFNRCIFCELCVRASREVDG
KNVFALGGRGLGKHLVVNAETGRLADTTLAADDLAANICPVGVILKKRVGFAVPIGERTYDAEPIHVHAMERDT

Sequences:

>Translated_234_residues
MKRQFLFDGRPVPFDEGQTILQAARAAGHYIPHLCWHPDFPPHGSCKLCTVKVGGRHVSSCAFPAREGMEVESDTPEINA
ERRALLQMLFVEGNHFCPGCEKSGNCQLQALAYDLEMTTPRFPHFYPDRPVDASHPDVLLDFNRCIFCELCVRASREVDG
KNVFALGGRGLGKHLVVNAETGRLADTTLAADDLAANICPVGVILKKRVGFAVPIGERTYDAEPIHVHAMERDT
>Mature_234_residues
MKRQFLFDGRPVPFDEGQTILQAARAAGHYIPHLCWHPDFPPHGSCKLCTVKVGGRHVSSCAFPAREGMEVESDTPEINA
ERRALLQMLFVEGNHFCPGCEKSGNCQLQALAYDLEMTTPRFPHFYPDRPVDASHPDVLLDFNRCIFCELCVRASREVDG
KNVFALGGRGLGKHLVVNAETGRLADTTLAADDLAANICPVGVILKKRVGFAVPIGERTYDAEPIHVHAMERDT

Specific function: Subunits alpha and gamma of hoxS constitute an NADH-- oxidoreductase [H]

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=228, Percent_Identity=28.0701754385965, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI145693161, Length=217, Percent_Identity=31.3364055299539, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193209088, Length=216, Percent_Identity=29.6296296296296, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566231, Length=217, Percent_Identity=30.8755760368664, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17565758, Length=217, Percent_Identity=30.8755760368664, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24640559, Length=216, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24640557, Length=216, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR016214
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.12.1.2 [H]

Molecular weight: Translated: 25853; Mature: 25853

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00642 COMPLEX1_75K_2 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQFLFDGRPVPFDEGQTILQAARAAGHYIPHLCWHPDFPPHGSCKLCTVKVGGRHVSS
CCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEEEECCEEECC
CAFPAREGMEVESDTPEINAERRALLQMLFVEGNHFCPGCEKSGNCQLQALAYDLEMTTP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEECCC
RFPHFYPDRPVDASHPDVLLDFNRCIFCELCVRASREVDGKNVFALGGRGLGKHLVVNAE
CCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECC
TGRLADTTLAADDLAANICPVGVILKKRVGFAVPIGERTYDAEPIHVHAMERDT
CCCCCCCEECHHHHHHHHCHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKRQFLFDGRPVPFDEGQTILQAARAAGHYIPHLCWHPDFPPHGSCKLCTVKVGGRHVSS
CCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEEEECCEEECC
CAFPAREGMEVESDTPEINAERRALLQMLFVEGNHFCPGCEKSGNCQLQALAYDLEMTTP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEECCC
RFPHFYPDRPVDASHPDVLLDFNRCIFCELCVRASREVDGKNVFALGGRGLGKHLVVNAE
CCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECC
TGRLADTTLAADDLAANICPVGVILKKRVGFAVPIGERTYDAEPIHVHAMERDT
CCCCCCCEECHHHHHHHHCHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2188945; 12948488; 2496982 [H]