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The map label for this gene is hoxF [H]

Identifier: 119897703

GI number: 119897703

Start: 1543481

End: 1545289

Strand: Direct

Name: hoxF [H]

Synonym: azo1412

Alternate gene names: 119897703

Gene position: 1543481-1545289 (Clockwise)

Preceding gene: 119897701

Following gene: 119897704

Centisome position: 35.27

GC content: 69.43

Gene sequence:

>1809_bases
ATGCAACCCACAGATGTACACGCCGGTGTGGCCGCCGCCGTGCAGCGCCACGGCGCCGCGCCGTCGTCGCTGTTGCAGGT
GCTGATTGCGGTGCAGGACCGGCTCGGTTATCTCGCGCCCTCCGCCTTGACGGAGGTCGCCGCGGCGCTCGACCTGCCCC
GCGCCCATGTGGAGGGCGTCGCCGGCTTTTACAGCTTTCTCCATACCTCTCCGGCGGGGCGTTACCGCATCCTGTTTGCC
GACAACGTCATCGAGCGCATGCAGGGCTCGGCGGAGTTGATGCATGCACTGTGCGGCAAGTTGTGGGTCGAGCCCGGCCG
CGTGTCCGAGGATGGCCTGGTCGGGGTGGCGCCGACATCGTGCATCGGCATGGGCGACCAGGGGCCGGCCGCGCTGGTGA
ACGGGCGGCCGATCACGCGCCTGACCCATGCCCGCATCAACGAGATCGCCGAACTGGTGCGCCGCGAGGTGCCGCTCGAA
CAGTGGCCGGCTGCGTTCTTCACGGTGGACGACAACGTCCGTCGCACCGATGCCTTGCTCGGCACCCGGCTGGCCGCGGG
TGACGCGCTGGCGGCGGCACTGAGGATGGGGCGGTCCGGGTGGCTGGACGAGATGCAGCGCTCCAATCTGCGCGGACGCG
GCGGGGCGGGTTTCACCACCGCGGTCAAATGGACCGCCTGCCGCGATGCCGCCGGGCCGCAGAAGGTCGTCGTGTGCAAT
GCGGACGAAGGCGAGCCCGGCACCTTCAAGGACAGGCTGCTGCTCACGCGCATGGCCGATGCGGTGTTCGAAGGCATGAC
GCTGGCCGCCTGGGCAACCGGCGCCCAGCTCGGCCTGCTTTATCTGCGTGGCGAGTACCGCTACCTGCTCGATGCCCTCA
ACGCCACGCTGACGCAGCGCCGTGCCGCCGGACTGCTCGGGCGCAACATCCTCGGCGAGGCGGGGTTCGACTTCGACATC
GCCATCCACCTCGGCGCGGGCGCCTATATCTGTGGCGAGGAGACGGCCCTGCTCGAGTCGCTGGAGGGCAAGCGCGGCAC
CCCGCGCATCCGCCCGCCATTCCCGGTCACCCACGGCTATCTCGGCCGTCCCACGGTGGTGAACAACGTGGAAACCCTGG
CCAAGACCTGTCTCATCGCCTGTGGCGGCGGGGCGGCCTTTGCCGCCACCGGCACCGCGCAATCCACCGGCACCAAACTG
CTGTCCATCTCGGGCGATTGTGCCGCGCCCGGCATCTACGAGTACCCCTTCGGCGTCACCGTGGAGCGCGTGCTCGAAGA
CTGCGGCGCCTCCGATACCCAGGCGGTGCAGGTGGGCGGCGCGGCGGGCATCACGCTGGCCGCGTATGAGTTCCAGCGCC
GTATCGCGTTCGAGGACGTTCCCACCGCGGGCGCATTCATGGTGTTCGACTCCGGGCGCGATCTGTTCGAGGTCGCGCGC
AACTTCGTCGCCTTCTTCGCCCACGAAAGCTGCGGCTTCTGCACGCCGTGCCGCGTGGGGACGGGGTTGCTGAAGGCCGC
GATGGACAAGTTCGCCAGCGGGCACGGCAGCCGGGGCGATCTCGCCGACATCGAGTGGATCGACCGCCTGCTGAAGAACG
CAAGCCATTGCGGCCTCGGCGCCTCGGCACCCAACCCGGTGCTCGATACGCTGTTGAAGTTCCGCTCCTTCTACGAGCGC
CGGATGCAGACGGCGGACTTCGAGCCGGCCTTCGATCTCGATCAGGCCTTGGCGCCGGCGCGCCGCGTCAGCGGCCGCGA
CGATGCGGCTGCCCACCTCGCCGCCCGCGCAACCGGAGACGCATCATGA

Upstream 100 bases:

>100_bases
ATGGGGACGCCCGCATGCGGCTCGCGGCCCGACCGTGTTGCAGATGCACATGGATTAGCGCACCTATAATGGTGACGCTC
TGCTAGCAAGGGACAGCGCC

Downstream 100 bases:

>100_bases
AACGCCAGTTCCTGTTCGACGGCCGTCCGGTGCCATTCGACGAGGGCCAGACCATCCTGCAGGCGGCGCGCGCCGCCGGC
CACTACATCCCGCATCTGTG

Product: hydrogen dehydrogenase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MQPTDVHAGVAAAVQRHGAAPSSLLQVLIAVQDRLGYLAPSALTEVAAALDLPRAHVEGVAGFYSFLHTSPAGRYRILFA
DNVIERMQGSAELMHALCGKLWVEPGRVSEDGLVGVAPTSCIGMGDQGPAALVNGRPITRLTHARINEIAELVRREVPLE
QWPAAFFTVDDNVRRTDALLGTRLAAGDALAAALRMGRSGWLDEMQRSNLRGRGGAGFTTAVKWTACRDAAGPQKVVVCN
ADEGEPGTFKDRLLLTRMADAVFEGMTLAAWATGAQLGLLYLRGEYRYLLDALNATLTQRRAAGLLGRNILGEAGFDFDI
AIHLGAGAYICGEETALLESLEGKRGTPRIRPPFPVTHGYLGRPTVVNNVETLAKTCLIACGGGAAFAATGTAQSTGTKL
LSISGDCAAPGIYEYPFGVTVERVLEDCGASDTQAVQVGGAAGITLAAYEFQRRIAFEDVPTAGAFMVFDSGRDLFEVAR
NFVAFFAHESCGFCTPCRVGTGLLKAAMDKFASGHGSRGDLADIEWIDRLLKNASHCGLGASAPNPVLDTLLKFRSFYER
RMQTADFEPAFDLDQALAPARRVSGRDDAAAHLAARATGDAS

Sequences:

>Translated_602_residues
MQPTDVHAGVAAAVQRHGAAPSSLLQVLIAVQDRLGYLAPSALTEVAAALDLPRAHVEGVAGFYSFLHTSPAGRYRILFA
DNVIERMQGSAELMHALCGKLWVEPGRVSEDGLVGVAPTSCIGMGDQGPAALVNGRPITRLTHARINEIAELVRREVPLE
QWPAAFFTVDDNVRRTDALLGTRLAAGDALAAALRMGRSGWLDEMQRSNLRGRGGAGFTTAVKWTACRDAAGPQKVVVCN
ADEGEPGTFKDRLLLTRMADAVFEGMTLAAWATGAQLGLLYLRGEYRYLLDALNATLTQRRAAGLLGRNILGEAGFDFDI
AIHLGAGAYICGEETALLESLEGKRGTPRIRPPFPVTHGYLGRPTVVNNVETLAKTCLIACGGGAAFAATGTAQSTGTKL
LSISGDCAAPGIYEYPFGVTVERVLEDCGASDTQAVQVGGAAGITLAAYEFQRRIAFEDVPTAGAFMVFDSGRDLFEVAR
NFVAFFAHESCGFCTPCRVGTGLLKAAMDKFASGHGSRGDLADIEWIDRLLKNASHCGLGASAPNPVLDTLLKFRSFYER
RMQTADFEPAFDLDQALAPARRVSGRDDAAAHLAARATGDAS
>Mature_602_residues
MQPTDVHAGVAAAVQRHGAAPSSLLQVLIAVQDRLGYLAPSALTEVAAALDLPRAHVEGVAGFYSFLHTSPAGRYRILFA
DNVIERMQGSAELMHALCGKLWVEPGRVSEDGLVGVAPTSCIGMGDQGPAALVNGRPITRLTHARINEIAELVRREVPLE
QWPAAFFTVDDNVRRTDALLGTRLAAGDALAAALRMGRSGWLDEMQRSNLRGRGGAGFTTAVKWTACRDAAGPQKVVVCN
ADEGEPGTFKDRLLLTRMADAVFEGMTLAAWATGAQLGLLYLRGEYRYLLDALNATLTQRRAAGLLGRNILGEAGFDFDI
AIHLGAGAYICGEETALLESLEGKRGTPRIRPPFPVTHGYLGRPTVVNNVETLAKTCLIACGGGAAFAATGTAQSTGTKL
LSISGDCAAPGIYEYPFGVTVERVLEDCGASDTQAVQVGGAAGITLAAYEFQRRIAFEDVPTAGAFMVFDSGRDLFEVAR
NFVAFFAHESCGFCTPCRVGTGLLKAAMDKFASGHGSRGDLADIEWIDRLLKNASHCGLGASAPNPVLDTLLKFRSFYER
RMQTADFEPAFDLDQALAPARRVSGRDDAAAHLAARATGDAS

Specific function: Subunits alpha and gamma of hoxS constitute an NADH-- oxidoreductase [H]

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=405, Percent_Identity=36.7901234567901, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI260656005, Length=405, Percent_Identity=36.7901234567901, Blast_Score=241, Evalue=2e-63,
Organism=Escherichia coli, GI1788620, Length=371, Percent_Identity=39.622641509434, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1788621, Length=127, Percent_Identity=33.8582677165354, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531727, Length=428, Percent_Identity=35.981308411215, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI19920794, Length=406, Percent_Identity=37.4384236453202, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI45550452, Length=395, Percent_Identity=35.9493670886076, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24653819, Length=396, Percent_Identity=30.050505050505, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24653817, Length=350, Percent_Identity=29.4285714285714, Blast_Score=132, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR002023
- InterPro:   IPR011538
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa; PF01512 Complex1_51K; PF10589 NADH_4Fe-4S [H]

EC number: =1.12.1.2 [H]

Molecular weight: Translated: 63873; Mature: 63873

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00644 COMPLEX1_51K_1 ; PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTDVHAGVAAAVQRHGAAPSSLLQVLIAVQDRLGYLAPSALTEVAAALDLPRAHVEGV
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
AGFYSFLHTSPAGRYRILFADNVIERMQGSAELMHALCGKLWVEPGRVSEDGLVGVAPTS
HHHHHHHHCCCCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCHH
CIGMGDQGPAALVNGRPITRLTHARINEIAELVRREVPLEQWPAAFFTVDDNVRRTDALL
HCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEECCCCHHHHHHH
GTRLAAGDALAAALRMGRSGWLDEMQRSNLRGRGGAGFTTAVKWTACRDAAGPQKVVVCN
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEEE
ADEGEPGTFKDRLLLTRMADAVFEGMTLAAWATGAQLGLLYLRGEYRYLLDALNATLTQR
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHH
RAAGLLGRNILGEAGFDFDIAIHLGAGAYICGEETALLESLEGKRGTPRIRPPFPVTHGY
HHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCC
LGRPTVVNNVETLAKTCLIACGGGAAFAATGTAQSTGTKLLSISGDCAAPGIYEYPFGVT
CCCCHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCCEECCCCCC
VERVLEDCGASDTQAVQVGGAAGITLAAYEFQRRIAFEDVPTAGAFMVFDSGRDLFEVAR
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHH
NFVAFFAHESCGFCTPCRVGTGLLKAAMDKFASGHGSRGDLADIEWIDRLLKNASHCGLG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
ASAPNPVLDTLLKFRSFYERRMQTADFEPAFDLDQALAPARRVSGRDDAAAHLAARATGD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCC
AS
CC
>Mature Secondary Structure
MQPTDVHAGVAAAVQRHGAAPSSLLQVLIAVQDRLGYLAPSALTEVAAALDLPRAHVEGV
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
AGFYSFLHTSPAGRYRILFADNVIERMQGSAELMHALCGKLWVEPGRVSEDGLVGVAPTS
HHHHHHHHCCCCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCHH
CIGMGDQGPAALVNGRPITRLTHARINEIAELVRREVPLEQWPAAFFTVDDNVRRTDALL
HCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEECCCCHHHHHHH
GTRLAAGDALAAALRMGRSGWLDEMQRSNLRGRGGAGFTTAVKWTACRDAAGPQKVVVCN
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEEE
ADEGEPGTFKDRLLLTRMADAVFEGMTLAAWATGAQLGLLYLRGEYRYLLDALNATLTQR
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHH
RAAGLLGRNILGEAGFDFDIAIHLGAGAYICGEETALLESLEGKRGTPRIRPPFPVTHGY
HHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCC
LGRPTVVNNVETLAKTCLIACGGGAAFAATGTAQSTGTKLLSISGDCAAPGIYEYPFGVT
CCCCHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCCEECCCCCC
VERVLEDCGASDTQAVQVGGAAGITLAAYEFQRRIAFEDVPTAGAFMVFDSGRDLFEVAR
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHH
NFVAFFAHESCGFCTPCRVGTGLLKAAMDKFASGHGSRGDLADIEWIDRLLKNASHCGLG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
ASAPNPVLDTLLKFRSFYERRMQTADFEPAFDLDQALAPARRVSGRDDAAAHLAARATGD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCC
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2188945; 12948488; 2496982 [H]