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The map label for this gene is dctS [H]

Identifier: 119897666

GI number: 119897666

Start: 1501285

End: 1503999

Strand: Direct

Name: dctS [H]

Synonym: azo1375

Alternate gene names: 119897666

Gene position: 1501285-1503999 (Clockwise)

Preceding gene: 119897661

Following gene: 119897667

Centisome position: 34.31

GC content: 66.59

Gene sequence:

>2715_bases
ATGCCCCATTCCGAGAAATCCACTGCGCTGCAGGCGCCCCTTCGCTGGTACTGGACGGCGCCGTATGCGGCGGTGGTGGT
GTTCGCATTGTCGATGCTCGCGCTGGTGTGGCTGCTGCAGACCCGCGAAGAAGAGAGCCAGCGCAGCGCTGTTGCGCGCG
ACGTGCAGTGGGCGGAGCAGACGATGCGGCTGCACATGCAGGGCACGGAGGAGTTCCTTGCCCAGCTCGCGCGCGATCTG
GCCAACGAGACGCTGGACCCCGATGCCTTTCAGGTTCGCGCCAACCAGCACATCGCCAACAGTGGCGAACTGGTCAATAT
CACCTGGGTGGGCGCGGACGAGATCGTGCGCTGGTCCGCTCCGTTCGATACCACCGACTGGCTGGCCGGGGATGCGTTGA
CGCCGCCCCAGGCACTTGCCTTCAACCGTGCGCGCGACTTCGGGCGCGCGGTCTATGGCGAGGCTTATCGCAATCCGCGC
GGCGGGATGGTGCTGGAGGTGTATGTGCCGGTGCGTCACGGTCGCGGCTTCCGTGGTGCCGTGGTGGGCGTCTATTCCAT
CGAAGGCATGGTGCGTTATCTGGTGCCCGGCTGGTTCGCCGAGAAGTACCGGCTTGCGCTGGAGAACGGCCGCGGCGACA
CGCTGGCGGTGAATTCCGCGGTGCGCGACACCGACGAGACGCTGTCTTTCCAGATTCCGCTCGACCCGCCAGGCAACGGC
CTCACGCTGCGGGCGACGGCCTTCAAGGCCCACGGCGCGGTGCCCCAGGCCTTGCCCGCGGTGCTGATCGTGGGCTTGTC
GGTCATCGTGCTATGGAGCCTGTGGATGCTGCGCGGCCATGTGCTGCGGCGCGTGCAGGTGGAAAAGGAGCGCGACCGGC
TGTTCAATCTGTCGCTCGACATGCTGTGCGTGGTGGGTTTCGACGGCGCGTTCCGCCGCTGCAACCCGGCCTTCGAGCAC
ATCCTCGGCTATGCCCCGGAGACCTTGCCCGGCCTGCCTTTGCTGGAGATCGTGCACCGTGACGACATCGCCTCGACGCT
GGAGCAGATGCGCCGGCTGGCGGGCGGCGAGCCGGTCAAGTTCGAAAACCGCTGCCGCTGCGCCGATGGTAACTACAAGT
GGTTGATGTGGAGCATCAACCCGGTGCGCGAGGAAAAGCTGGTGTACGCGGTGGCGCACGACATCACCGGGCGCAAGGCC
GCGGAAGAAGCGCTGCGGGCCGAATCCGCCTTCCGCAAGGCGATGGAGGAGTCGGTGCTCACCGGCCTGCGCGCCATCGA
CCTCAGCGGCCGCATCATCTATGTGAACTCCGCGTTCTGCCGCATGGTGGGTTTCAGCGAGAAGGAACTGGTGGGCGCCA
GCGAGCCTTTCCCGTACTGGCCGTCGGAGGACCTGGAGTTCTGCCGGCGCAACCTGGAGCTGACGCTGGCCGGGCGGGCG
CCGCCCAGCGGCTTCGAGATGCGCATCCGGCGCAAGAATGGCGAACGCCTGGACGCGCGCTTCTACCTTTCTCCGCTGAT
CGATCTCGAAGGTCGCCAGACCGGCTGGATGGCTTCGGTCACCGACATCACCGAGCCGAAGCGGGTGCGCGCCGCCCTGG
AGGCGACGCACGAGCGCTTCGAAGCCGTTCTGGACGGGCTGGACGCGGCGGTCTTCGTCGCCGACGCACGCACCGACGAA
ATCCTCTTCGCCAACCGCGCGTTCAAGACCATCCACGGTTTCGACACCGTCGGCCGCACCGTGCGTGGCGTTGCCGTGCC
GCAGCCCGAGCGCGGCGACTACCGGGTCGATCCGCGCGGGCTGACGGTGGGCGATCTTCCGCGCGAACTCTTCGATGGCG
AACTCCAGCACCCCTTGTCAGGACGCTGGTACCACGTCCGCGAACACGCCACGCGCTGGGTGGATGGCCGCGTCGTGCGG
ATGGGCATCGCCACCGACATCACCGACCGCAAGCAGACCGCCGAGGTTTCGCGCCAGCAGGAAGAACGGCTGCAGCGCAC
CGCGCGCCTGATCACCATGGGCGAGATGGCCTCGACGCTCGCCCACGAACTCAATCAGCCGCTGTCGGCCATCGCCAACT
ACTGCGCCGGCTGCGTCACCCGCATGCAGGGTGACAACTGGAAGCAGGAGGACATTCTCGGTGCGATGCAGAAGGCGAGC
TTTCAGGCCGAGCGCGCCGGCAAGATCATTCGCCGCATCCGCGAGTTCGTGAAGAAGAGCGAACCCCGCCGCAGCGCGGT
GCAGATCGGCGAGGTGCTGGACGACGCCCTGGGTTTTGCGGACATCGATGCACGTCGGGTCGGTATCCGCATTGTCGCTG
CGGTGGATCCCGATCTGCCCGCGGTGTATGCCGACCGGATCATGATCGAGCAGGTGGTGCTCAATCTGGTCCGCAACGGC
CTCGATGCGATGGCCGACACCTTGCCGGAGGAGCGCGAACTGGTCGTCCGTGCGCGCGCCTTTGGTCCTCACGCGGTGGA
GGTGGCGGTGATCGACCGCGGCCATGGCATCGGCGAAGAAGACCGGCAGCGGCTGTTCACACCGTTCTACACGACCAAGG
CGGAGGGCATGGGCATGGGGCTCAACATCTGCCGGTCGATCATCGAGTTCCACGATGGTCGTCTGGTTGTCGACGGCAAC
CCCGAAGGCGGTACCATATTTTCCTTCACCCTGCCCACGGAGGCCGCCAGTGAGCGTATTGCCCGTCGCGCCTGA

Upstream 100 bases:

>100_bases
TGCTAGGGTTATACCGAATGTCTGGGCCGGCCGCGCGCCGCAACAATGACACAATGCGGTTTTCCTCCTTCGCCGCCCGC
CGCCGCCCTATCCCTCGTCC

Downstream 100 bases:

>100_bases
TCAGGAAATCTTCATCGTCGATGACGACGATGCCTTGCGCGATTCCCTGGTGTGGATGCTGGAATCCAGCGGCTACAAGG
TTGTCGCTTTCGACTCCGCC

Product: putative two-component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 904; Mature: 903

Protein sequence:

>904_residues
MPHSEKSTALQAPLRWYWTAPYAAVVVFALSMLALVWLLQTREEESQRSAVARDVQWAEQTMRLHMQGTEEFLAQLARDL
ANETLDPDAFQVRANQHIANSGELVNITWVGADEIVRWSAPFDTTDWLAGDALTPPQALAFNRARDFGRAVYGEAYRNPR
GGMVLEVYVPVRHGRGFRGAVVGVYSIEGMVRYLVPGWFAEKYRLALENGRGDTLAVNSAVRDTDETLSFQIPLDPPGNG
LTLRATAFKAHGAVPQALPAVLIVGLSVIVLWSLWMLRGHVLRRVQVEKERDRLFNLSLDMLCVVGFDGAFRRCNPAFEH
ILGYAPETLPGLPLLEIVHRDDIASTLEQMRRLAGGEPVKFENRCRCADGNYKWLMWSINPVREEKLVYAVAHDITGRKA
AEEALRAESAFRKAMEESVLTGLRAIDLSGRIIYVNSAFCRMVGFSEKELVGASEPFPYWPSEDLEFCRRNLELTLAGRA
PPSGFEMRIRRKNGERLDARFYLSPLIDLEGRQTGWMASVTDITEPKRVRAALEATHERFEAVLDGLDAAVFVADARTDE
ILFANRAFKTIHGFDTVGRTVRGVAVPQPERGDYRVDPRGLTVGDLPRELFDGELQHPLSGRWYHVREHATRWVDGRVVR
MGIATDITDRKQTAEVSRQQEERLQRTARLITMGEMASTLAHELNQPLSAIANYCAGCVTRMQGDNWKQEDILGAMQKAS
FQAERAGKIIRRIREFVKKSEPRRSAVQIGEVLDDALGFADIDARRVGIRIVAAVDPDLPAVYADRIMIEQVVLNLVRNG
LDAMADTLPEERELVVRARAFGPHAVEVAVIDRGHGIGEEDRQRLFTPFYTTKAEGMGMGLNICRSIIEFHDGRLVVDGN
PEGGTIFSFTLPTEAASERIARRA

Sequences:

>Translated_904_residues
MPHSEKSTALQAPLRWYWTAPYAAVVVFALSMLALVWLLQTREEESQRSAVARDVQWAEQTMRLHMQGTEEFLAQLARDL
ANETLDPDAFQVRANQHIANSGELVNITWVGADEIVRWSAPFDTTDWLAGDALTPPQALAFNRARDFGRAVYGEAYRNPR
GGMVLEVYVPVRHGRGFRGAVVGVYSIEGMVRYLVPGWFAEKYRLALENGRGDTLAVNSAVRDTDETLSFQIPLDPPGNG
LTLRATAFKAHGAVPQALPAVLIVGLSVIVLWSLWMLRGHVLRRVQVEKERDRLFNLSLDMLCVVGFDGAFRRCNPAFEH
ILGYAPETLPGLPLLEIVHRDDIASTLEQMRRLAGGEPVKFENRCRCADGNYKWLMWSINPVREEKLVYAVAHDITGRKA
AEEALRAESAFRKAMEESVLTGLRAIDLSGRIIYVNSAFCRMVGFSEKELVGASEPFPYWPSEDLEFCRRNLELTLAGRA
PPSGFEMRIRRKNGERLDARFYLSPLIDLEGRQTGWMASVTDITEPKRVRAALEATHERFEAVLDGLDAAVFVADARTDE
ILFANRAFKTIHGFDTVGRTVRGVAVPQPERGDYRVDPRGLTVGDLPRELFDGELQHPLSGRWYHVREHATRWVDGRVVR
MGIATDITDRKQTAEVSRQQEERLQRTARLITMGEMASTLAHELNQPLSAIANYCAGCVTRMQGDNWKQEDILGAMQKAS
FQAERAGKIIRRIREFVKKSEPRRSAVQIGEVLDDALGFADIDARRVGIRIVAAVDPDLPAVYADRIMIEQVVLNLVRNG
LDAMADTLPEERELVVRARAFGPHAVEVAVIDRGHGIGEEDRQRLFTPFYTTKAEGMGMGLNICRSIIEFHDGRLVVDGN
PEGGTIFSFTLPTEAASERIARRA
>Mature_903_residues
PHSEKSTALQAPLRWYWTAPYAAVVVFALSMLALVWLLQTREEESQRSAVARDVQWAEQTMRLHMQGTEEFLAQLARDLA
NETLDPDAFQVRANQHIANSGELVNITWVGADEIVRWSAPFDTTDWLAGDALTPPQALAFNRARDFGRAVYGEAYRNPRG
GMVLEVYVPVRHGRGFRGAVVGVYSIEGMVRYLVPGWFAEKYRLALENGRGDTLAVNSAVRDTDETLSFQIPLDPPGNGL
TLRATAFKAHGAVPQALPAVLIVGLSVIVLWSLWMLRGHVLRRVQVEKERDRLFNLSLDMLCVVGFDGAFRRCNPAFEHI
LGYAPETLPGLPLLEIVHRDDIASTLEQMRRLAGGEPVKFENRCRCADGNYKWLMWSINPVREEKLVYAVAHDITGRKAA
EEALRAESAFRKAMEESVLTGLRAIDLSGRIIYVNSAFCRMVGFSEKELVGASEPFPYWPSEDLEFCRRNLELTLAGRAP
PSGFEMRIRRKNGERLDARFYLSPLIDLEGRQTGWMASVTDITEPKRVRAALEATHERFEAVLDGLDAAVFVADARTDEI
LFANRAFKTIHGFDTVGRTVRGVAVPQPERGDYRVDPRGLTVGDLPRELFDGELQHPLSGRWYHVREHATRWVDGRVVRM
GIATDITDRKQTAEVSRQQEERLQRTARLITMGEMASTLAHELNQPLSAIANYCAGCVTRMQGDNWKQEDILGAMQKASF
QAERAGKIIRRIREFVKKSEPRRSAVQIGEVLDDALGFADIDARRVGIRIVAAVDPDLPAVYADRIMIEQVVLNLVRNGL
DAMADTLPEERELVVRARAFGPHAVEVAVIDRGHGIGEEDRQRLFTPFYTTKAEGMGMGLNICRSIIEFHDGRLVVDGNP
EGGTIFSFTLPTEAASERIARRA

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=26.4, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=28.4518828451883, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI1790300, Length=290, Percent_Identity=26.8965517241379, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=26.3736263736264, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 101267; Mature: 101136

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHSEKSTALQAPLRWYWTAPYAAVVVFALSMLALVWLLQTREEESQRSAVARDVQWAEQ
CCCCCCCHHHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMRLHMQGTEEFLAQLARDLANETLDPDAFQVRANQHIANSGELVNITWVGADEIVRWSA
HHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEEECHHHEEEECC
PFDTTDWLAGDALTPPQALAFNRARDFGRAVYGEAYRNPRGGMVLEVYVPVRHGRGFRGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCC
VVGVYSIEGMVRYLVPGWFAEKYRLALENGRGDTLAVNSAVRDTDETLSFQIPLDPPGNG
EEEEHHHHHHHHHHCCCHHHHHHHHHEECCCCCEEEECCHHCCCCCCEEEEEECCCCCCC
LTLRATAFKAHGAVPQALPAVLIVGLSVIVLWSLWMLRGHVLRRVQVEKERDRLFNLSLD
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
MLCVVGFDGAFRRCNPAFEHILGYAPETLPGLPLLEIVHRDDIASTLEQMRRLAGGEPVK
EEEEECCCCHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FENRCRCADGNYKWLMWSINPVREEKLVYAVAHDITGRKAAEEALRAESAFRKAMEESVL
CCCCEEECCCCEEEEEEECCCCCHHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TGLRAIDLSGRIIYVNSAFCRMVGFSEKELVGASEPFPYWPSEDLEFCRRNLELTLAGRA
HHHHEEECCCEEEEEEHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEECCC
PPSGFEMRIRRKNGERLDARFYLSPLIDLEGRQTGWMASVTDITEPKRVRAALEATHERF
CCCCCEEEEECCCCCEEEEEEEECHHEECCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHH
EAVLDGLDAAVFVADARTDEILFANRAFKTIHGFDTVGRTVRGVAVPQPERGDYRVDPRG
HHHHCCCCEEEEEECCCCCCEEEECHHHHHHHCHHHHHHHHCCCCCCCCCCCCEEECCCC
LTVGDLPRELFDGELQHPLSGRWYHVREHATRWVDGRVVRMGIATDITDRKQTAEVSRQQ
CCHHCCCHHHCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHH
EERLQRTARLITMGEMASTLAHELNQPLSAIANYCAGCVTRMQGDNWKQEDILGAMQKAS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FQAERAGKIIRRIREFVKKSEPRRSAVQIGEVLDDALGFADIDARRVGIRIVAAVDPDLP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCC
AVYADRIMIEQVVLNLVRNGLDAMADTLPEERELVVRARAFGPHAVEVAVIDRGHGIGEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCEEEEEEEECCCCCCHH
DRQRLFTPFYTTKAEGMGMGLNICRSIIEFHDGRLVVDGNPEGGTIFSFTLPTEAASERI
HHHHHCCCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCHHHHHHH
ARRA
HHCC
>Mature Secondary Structure 
PHSEKSTALQAPLRWYWTAPYAAVVVFALSMLALVWLLQTREEESQRSAVARDVQWAEQ
CCCCCCHHHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMRLHMQGTEEFLAQLARDLANETLDPDAFQVRANQHIANSGELVNITWVGADEIVRWSA
HHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEEECHHHEEEECC
PFDTTDWLAGDALTPPQALAFNRARDFGRAVYGEAYRNPRGGMVLEVYVPVRHGRGFRGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCC
VVGVYSIEGMVRYLVPGWFAEKYRLALENGRGDTLAVNSAVRDTDETLSFQIPLDPPGNG
EEEEHHHHHHHHHHCCCHHHHHHHHHEECCCCCEEEECCHHCCCCCCEEEEEECCCCCCC
LTLRATAFKAHGAVPQALPAVLIVGLSVIVLWSLWMLRGHVLRRVQVEKERDRLFNLSLD
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
MLCVVGFDGAFRRCNPAFEHILGYAPETLPGLPLLEIVHRDDIASTLEQMRRLAGGEPVK
EEEEECCCCHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FENRCRCADGNYKWLMWSINPVREEKLVYAVAHDITGRKAAEEALRAESAFRKAMEESVL
CCCCEEECCCCEEEEEEECCCCCHHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TGLRAIDLSGRIIYVNSAFCRMVGFSEKELVGASEPFPYWPSEDLEFCRRNLELTLAGRA
HHHHEEECCCEEEEEEHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEECCC
PPSGFEMRIRRKNGERLDARFYLSPLIDLEGRQTGWMASVTDITEPKRVRAALEATHERF
CCCCCEEEEECCCCCEEEEEEEECHHEECCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHH
EAVLDGLDAAVFVADARTDEILFANRAFKTIHGFDTVGRTVRGVAVPQPERGDYRVDPRG
HHHHCCCCEEEEEECCCCCCEEEECHHHHHHHCHHHHHHHHCCCCCCCCCCCCEEECCCC
LTVGDLPRELFDGELQHPLSGRWYHVREHATRWVDGRVVRMGIATDITDRKQTAEVSRQQ
CCHHCCCHHHCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHH
EERLQRTARLITMGEMASTLAHELNQPLSAIANYCAGCVTRMQGDNWKQEDILGAMQKAS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FQAERAGKIIRRIREFVKKSEPRRSAVQIGEVLDDALGFADIDARRVGIRIVAAVDPDLP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCC
AVYADRIMIEQVVLNLVRNGLDAMADTLPEERELVVRARAFGPHAVEVAVIDRGHGIGEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEECCCCCEEEEEEEECCCCCCHH
DRQRLFTPFYTTKAEGMGMGLNICRSIIEFHDGRLVVDGNPEGGTIFSFTLPTEAASERI
HHHHHCCCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCHHHHHHH
ARRA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]