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The map label for this gene is aer [H]

Identifier: 119897661

GI number: 119897661

Start: 1491592

End: 1493208

Strand: Direct

Name: aer [H]

Synonym: azo1370

Alternate gene names: 119897661

Gene position: 1491592-1493208 (Clockwise)

Preceding gene: 119897660

Following gene: 119897666

Centisome position: 34.09

GC content: 69.57

Gene sequence:

>1617_bases
ATGATCGACAACAAGTCAGCCACTACGCGGGAACATGCTTTCCCCCGCGGGAAGCTGGTCGTGCTCAAGTACGACATGGA
CTTCAAGATCACCTACGCGAACGAGGCCTGCGCCGAGATGGTCGGCAGCACGCGCGAGGCGTTGATCGGCAGCAGCATCA
AGGAGATCGCCCATCCCGACGTGCCGCAGGAACTGCTCGCCGACGTGCGCGGTACAACCTCGTCGGGGCGGCCCTGGCTG
GGCCTGTCCAAGCTCAAGCATCGCGATGGCGGCGTCGCATGGTCGACCGCGCTGACGATTCCGGTCCGTCAGAACGGCCG
CAACGTCGGTTTCATGAGCCTGCGCAGCGAGGCCCCGCGGGAGCGGGTGCAGGCGGAGGAGGCGCTTTACGAGGCGATGC
GGCGCAAGCAGGCGCGCTACCGTAACCTCGACATGCCGGTGCGCCGCGCGCTGTCGAGCGCGGCGATGCTGTGCGCGCTA
GGCGGTCTCGGCAGCAGCCTCGCGCTGTTGCTGGTGTTCGCCGGACTGGCGCTGGACGCGGGGGCGTGGGCATATGCCCT
GATCGCTGCGGGTGGCCTCGGCCTGGCCGGGATGCTGGCGTTGGTGGCCACGCTGTGGCGGCGTTCGATCACCGAGTCGG
CGACCATGCTGAAGGCTTTCGAGCGCATCGCCGAGGGCGACCTGACCAGCACGCTGCCGGTCGGCCGGTCCGACGAAATG
GGGCGGCTGATGGAATCGCTGATGTACATGCAGGGCCGGCTGAAGGTGATGCTGGACGAAATCCGCCTTGCGGCGGCATT
GACCGACAAGGAGAACGCCGCGTTGCGCGCCGAGGTGCAGTCGCTCAAGGATGCCGCCGACGCCCAGCGCGACCGCATCC
TGTCGGTGTCGGCGGCGTCCGAGCAGAACAGCGCTGCGGTTGCCGAGGTGGCCGGTGGCGCCAAGGCTTCGGCGCAGGCC
GCGAACGAGGCGCTGGCGCTGGTGGCCGAAGGGCGCGCCCATCTCAACCAGACGGTGGGCGCCGCCCGCCGTACCGTGGA
CGCGGTGGAGGGCGCGAACCGCGCGATGCGCGCGCTGGGGGATTCGATCCAGAGCGTGGCGACGATCTCGGCCGAGATCC
GCGAAATTTCTGACCAGACCAACCTGCTCGCACTCAATGCGGCGATCGAGGCGGCGCGCGCGGGCGAAGTCGGCCGCGGC
TTCGCGGTGGTGGCGGACGAGGTGCGCAAACTCGCCGAGCGCACGGCCCACTGCACCGGCAACATCGCCAGCATGGTCGG
CGAAATCCGGCGGGTATCCGACGAAGTGGCGGGCGACATGGACAAGGCCGCGGGGCTGGTCGGCGAGGCGAGCGGCAGCG
CCGGCGACAGCCTCGGCATCATGGGCCGCATCGAGCAGGGCAGCGGCCGTGTCGCCGGCCTGGCCGGACACATTGCGGAT
GCTTCGGCCGAGCACTCCACCGCCTCGGAGCAGATCGCGCAGGACATGGAGCTGATCTCCGGCCTGGTGGAGCGCAGCGC
CGCCGGCATCGACGCGGTGGACCGCGCCGCCGACGGCGTGCAGTGCAACGTCGGCAATCTCAAGCAGCTGGTCGGCTTCT
TCCGCGTGGTGGCCTGA

Upstream 100 bases:

>100_bases
CTTCATGTCAAAGTGTTTGACACGTAAACGATTAATAAATAAAAAGACGAGGTCGTTAATAAGAAAACTCCCCCAACGGC
ATCACCGACGAGAGAACAGC

Downstream 100 bases:

>100_bases
CGGAGCGCGCGGAGCAGCCCAACAAAAAAGAACCGCCCGAGGGCGGTTCTTTTCTTGCGCGGGCGTACTTGCCGCCTTAC
TTCTTGCGCATCGGTGGCAG

Product: putative aerotaxis receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MIDNKSATTREHAFPRGKLVVLKYDMDFKITYANEACAEMVGSTREALIGSSIKEIAHPDVPQELLADVRGTTSSGRPWL
GLSKLKHRDGGVAWSTALTIPVRQNGRNVGFMSLRSEAPRERVQAEEALYEAMRRKQARYRNLDMPVRRALSSAAMLCAL
GGLGSSLALLLVFAGLALDAGAWAYALIAAGGLGLAGMLALVATLWRRSITESATMLKAFERIAEGDLTSTLPVGRSDEM
GRLMESLMYMQGRLKVMLDEIRLAAALTDKENAALRAEVQSLKDAADAQRDRILSVSAASEQNSAAVAEVAGGAKASAQA
ANEALALVAEGRAHLNQTVGAARRTVDAVEGANRAMRALGDSIQSVATISAEIREISDQTNLLALNAAIEAARAGEVGRG
FAVVADEVRKLAERTAHCTGNIASMVGEIRRVSDEVAGDMDKAAGLVGEASGSAGDSLGIMGRIEQGSGRVAGLAGHIAD
ASAEHSTASEQIAQDMELISGLVERSAAGIDAVDRAADGVQCNVGNLKQLVGFFRVVA

Sequences:

>Translated_538_residues
MIDNKSATTREHAFPRGKLVVLKYDMDFKITYANEACAEMVGSTREALIGSSIKEIAHPDVPQELLADVRGTTSSGRPWL
GLSKLKHRDGGVAWSTALTIPVRQNGRNVGFMSLRSEAPRERVQAEEALYEAMRRKQARYRNLDMPVRRALSSAAMLCAL
GGLGSSLALLLVFAGLALDAGAWAYALIAAGGLGLAGMLALVATLWRRSITESATMLKAFERIAEGDLTSTLPVGRSDEM
GRLMESLMYMQGRLKVMLDEIRLAAALTDKENAALRAEVQSLKDAADAQRDRILSVSAASEQNSAAVAEVAGGAKASAQA
ANEALALVAEGRAHLNQTVGAARRTVDAVEGANRAMRALGDSIQSVATISAEIREISDQTNLLALNAAIEAARAGEVGRG
FAVVADEVRKLAERTAHCTGNIASMVGEIRRVSDEVAGDMDKAAGLVGEASGSAGDSLGIMGRIEQGSGRVAGLAGHIAD
ASAEHSTASEQIAQDMELISGLVERSAAGIDAVDRAADGVQCNVGNLKQLVGFFRVVA
>Mature_538_residues
MIDNKSATTREHAFPRGKLVVLKYDMDFKITYANEACAEMVGSTREALIGSSIKEIAHPDVPQELLADVRGTTSSGRPWL
GLSKLKHRDGGVAWSTALTIPVRQNGRNVGFMSLRSEAPRERVQAEEALYEAMRRKQARYRNLDMPVRRALSSAAMLCAL
GGLGSSLALLLVFAGLALDAGAWAYALIAAGGLGLAGMLALVATLWRRSITESATMLKAFERIAEGDLTSTLPVGRSDEM
GRLMESLMYMQGRLKVMLDEIRLAAALTDKENAALRAEVQSLKDAADAQRDRILSVSAASEQNSAAVAEVAGGAKASAQA
ANEALALVAEGRAHLNQTVGAARRTVDAVEGANRAMRALGDSIQSVATISAEIREISDQTNLLALNAAIEAARAGEVGRG
FAVVADEVRKLAERTAHCTGNIASMVGEIRRVSDEVAGDMDKAAGLVGEASGSAGDSLGIMGRIEQGSGRVAGLAGHIAD
ASAEHSTASEQIAQDMELISGLVERSAAGIDAVDRAADGVQCNVGNLKQLVGFFRVVA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=412, Percent_Identity=30.0970873786408, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787690, Length=359, Percent_Identity=32.3119777158774, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI2367378, Length=279, Percent_Identity=34.4086021505376, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788195, Length=333, Percent_Identity=30.9309309309309, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788194, Length=333, Percent_Identity=27.6276276276276, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56521; Mature: 56521

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNKSATTREHAFPRGKLVVLKYDMDFKITYANEACAEMVGSTREALIGSSIKEIAHPD
CCCCCCCCCHHHCCCCCCEEEEEECCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCC
VPQELLADVRGTTSSGRPWLGLSKLKHRDGGVAWSTALTIPVRQNGRNVGFMSLRSEAPR
CCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEHHHHCCHH
ERVQAEEALYEAMRRKQARYRNLDMPVRRALSSAAMLCALGGLGSSLALLLVFAGLALDA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GAWAYALIAAGGLGLAGMLALVATLWRRSITESATMLKAFERIAEGDLTSTLPVGRSDEM
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
GRLMESLMYMQGRLKVMLDEIRLAAALTDKENAALRAEVQSLKDAADAQRDRILSVSAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCC
EQNSAAVAEVAGGAKASAQAANEALALVAEGRAHLNQTVGAARRTVDAVEGANRAMRALG
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSIQSVATISAEIREISDQTNLLALNAAIEAARAGEVGRGFAVVADEVRKLAERTAHCTG
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
NIASMVGEIRRVSDEVAGDMDKAAGLVGEASGSAGDSLGIMGRIEQGSGRVAGLAGHIAD
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHC
ASAEHSTASEQIAQDMELISGLVERSAAGIDAVDRAADGVQCNVGNLKQLVGFFRVVA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDNKSATTREHAFPRGKLVVLKYDMDFKITYANEACAEMVGSTREALIGSSIKEIAHPD
CCCCCCCCCHHHCCCCCCEEEEEECCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCC
VPQELLADVRGTTSSGRPWLGLSKLKHRDGGVAWSTALTIPVRQNGRNVGFMSLRSEAPR
CCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEHHHHCCHH
ERVQAEEALYEAMRRKQARYRNLDMPVRRALSSAAMLCALGGLGSSLALLLVFAGLALDA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GAWAYALIAAGGLGLAGMLALVATLWRRSITESATMLKAFERIAEGDLTSTLPVGRSDEM
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
GRLMESLMYMQGRLKVMLDEIRLAAALTDKENAALRAEVQSLKDAADAQRDRILSVSAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCC
EQNSAAVAEVAGGAKASAQAANEALALVAEGRAHLNQTVGAARRTVDAVEGANRAMRALG
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSIQSVATISAEIREISDQTNLLALNAAIEAARAGEVGRGFAVVADEVRKLAERTAHCTG
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
NIASMVGEIRRVSDEVAGDMDKAAGLVGEASGSAGDSLGIMGRIEQGSGRVAGLAGHIAD
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHC
ASAEHSTASEQIAQDMELISGLVERSAAGIDAVDRAADGVQCNVGNLKQLVGFFRVVA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]