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The map label for this gene is stc [H]

Identifier: 119897516

GI number: 119897516

Start: 1318385

End: 1320445

Strand: Direct

Name: stc [H]

Synonym: azo1225

Alternate gene names: 119897516

Gene position: 1318385-1320445 (Clockwise)

Preceding gene: 119897515

Following gene: 119897517

Centisome position: 30.13

GC content: 71.52

Gene sequence:

>2061_bases
ATGCGGGAACTTTCCTACCGAAAGTCCGGCGTACGGTTTTCCGCCGAACTGCGGCCCAATCCGGCTGCGCAGTGCAGCGG
GCGCGAGCTGGTCTCCATCGACCGCGCCACCTACGCCGCCTGGGAACGCTTCGTCACCGGCGAAGCCCTGCCGCCGAGCA
CCATCGAATCACCGGTGCTCGATTCCTGGCGCCGCAGCCGCGATGCCGGGGTCAATCCGGTGGGGCGCGCCGCCCCGGTC
GCCGCGCGGGGTGACGACATGGAACTGCTGCGCCGCCGCCACCGCGAGCTGATGGCCGCGGCGTCCAATCTCTTCGCCCA
CACCGGCGACCTGCTCGCCGGCTCGCACTCCATCATGCTGCTGACCAGCCCGGAAGGCGTGGTGCTGGATGCCGCCGGTG
ATGCCGCCACGCTGGATGCCGCGCGCGACATCCACCTGATGACCGGCGGCAACTGGTGCGAGGCGGTGGTGGGCACCAAC
GGCATCGGCACCGCGATCGCCACCCGCTGCCCGGCCCAGATCCACGGCGCCGAGCACTTCTGCGAAGGCATCCAGGGCTG
GACCTGTGCGGCGGCGCCGATCTTCGAGCCCGGCACCCAGGACATCCTCGGCGTGCTCGACATCTCCGGCCCGCCGCAGA
CCTTCCAGCGCAACAACCTGCTGCTCGCGGTCTCGGTGGCACGCCAGATCGAGATGGCGCTGTCCCACAGCGCGCTGGGC
GAACGGCTGCGCCTGCTGGAACACTGTATGAACCGCCTGTCGCTGGCCGACGCCGCCGGCATGGTGGCGATCGACCGCCA
GGGCCGCCTGATCCACTCTGCCGGCCGCGTGCCCCTGCCGGTGGGCGTGGGCGAGCGCCTGCCCGGCTTCCGCCCTCATG
CCGACCTGGAGGAATGGGCTGCGCACCTGCCCGAAGGGCTGCGCCCGGAATGGCTGCACCCGGTGGTGGCCGGCGGGCGC
ACCGTCGGCGCGGTGGTGCTGGTGCCGGGCCGCGGCGTGCGCAATTCGCCGGTGGCGCGGCTGGCCGAGCAAAGCTCCGA
GGCCGACCCGCGCCGCTCCTGTTTCGACAACATCCTTGGCCGCAGCCCGGCGATGCGCGAGGCCACCGACCTTGGCCGCC
GGCTGGCGACCAAGCGCGTGCCGGTGCTGGTGGAAGGCGAAACCGGCGTCGGCAAGGAGCTGTTCGCACGCGCGCTGCAC
GGCGGCGAACACCTCGGCGGCCCCTTCATCACCTACAACTGCGGCGCGGCCTCCAAGGAACTGATCGCCGCCGACCTCTT
CGGCCACGTGCGCGGCGCCTTCACCGGCGCCACCAACGACGGCCGCCCGGGCCGCTTCGAACTCGCCAACGGCGGCACGC
TGTGCCTGGACGAAATCGGCGAGATGCCGCTCGATCTGCAGCCGGTGCTGCTGCGCGCGCTGGAAGAAGGCATCGTCTAT
CGCCTGGGCGACACCCAGCCGCGCCGGGTGGACGTACGCCTGATCGCGATGACCAACCGCAACCTGCGCGAAGAGGTCGC
CGCCGGCCGCTTCCGCCGCGACCTCTACTACCGCATCGGCGTCACCCGCCTGCGCATCCCGCCGCTGCGCGAGCGCGACG
GCGACATCCCGCTGCTCGCCAGCCACTTCTGTACGCAGCTGGCCGAGCGCCACGGCGTGCCGCGGCGCGAATTCGGCCCC
GAGGTGCTGGATGCGCTGCAGGCCTACTGCTGGCCCGGCAACGTGCGCGAACTGCGCAACGTCGTCGAATCCCTGCTGTT
GATGGATTCCACCCCGCAGGTGCGGGTGGATGAACTGCCGGAAGAAATCCTCGCCTCGGTCCCGCAGGCGGCGCGCCCCG
CCGCAGAAGGCGCCGAACCCGAATGCCCCAGCCTGGAAGCCGCCGAGCGCCGCGCGATCCAGAAGGCGGTCATCAACTTC
CAGGGCAACCTCGCCCAGGCCGCCCGCCTGCTCGGCATCTCGCGCAGCACCCTGTATCGCAAGGTGGAACGCTATGCGCT
GGAGGATTTCGTGCGCGCGGCGGGGGGGAATCTGGAGGGGGAGGGCGGGGCGGGGGATTAG

Upstream 100 bases:

>100_bases
AGCCCGGCAACATGCACACAAGATGCATTGAAAAAAGAATAAGGGCGGACCTGGCCGGCGCACGATCGACCCGTAGTCCG
TCCCTCCAGAGGAGTGAGAC

Downstream 100 bases:

>100_bases
CGCTTTCCGTCCGCCCCGTGCGCGTTGCATTCCTGTCGGCCGCCGGGGCTTGCCCGGCGGCCGATTCGTTTGCCGACGGT
CTTTCTGGCGGCACCGCGTG

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MRELSYRKSGVRFSAELRPNPAAQCSGRELVSIDRATYAAWERFVTGEALPPSTIESPVLDSWRRSRDAGVNPVGRAAPV
AARGDDMELLRRRHRELMAAASNLFAHTGDLLAGSHSIMLLTSPEGVVLDAAGDAATLDAARDIHLMTGGNWCEAVVGTN
GIGTAIATRCPAQIHGAEHFCEGIQGWTCAAAPIFEPGTQDILGVLDISGPPQTFQRNNLLLAVSVARQIEMALSHSALG
ERLRLLEHCMNRLSLADAAGMVAIDRQGRLIHSAGRVPLPVGVGERLPGFRPHADLEEWAAHLPEGLRPEWLHPVVAGGR
TVGAVVLVPGRGVRNSPVARLAEQSSEADPRRSCFDNILGRSPAMREATDLGRRLATKRVPVLVEGETGVGKELFARALH
GGEHLGGPFITYNCGAASKELIAADLFGHVRGAFTGATNDGRPGRFELANGGTLCLDEIGEMPLDLQPVLLRALEEGIVY
RLGDTQPRRVDVRLIAMTNRNLREEVAAGRFRRDLYYRIGVTRLRIPPLRERDGDIPLLASHFCTQLAERHGVPRREFGP
EVLDALQAYCWPGNVRELRNVVESLLLMDSTPQVRVDELPEEILASVPQAARPAAEGAEPECPSLEAAERRAIQKAVINF
QGNLAQAARLLGISRSTLYRKVERYALEDFVRAAGGNLEGEGGAGD

Sequences:

>Translated_686_residues
MRELSYRKSGVRFSAELRPNPAAQCSGRELVSIDRATYAAWERFVTGEALPPSTIESPVLDSWRRSRDAGVNPVGRAAPV
AARGDDMELLRRRHRELMAAASNLFAHTGDLLAGSHSIMLLTSPEGVVLDAAGDAATLDAARDIHLMTGGNWCEAVVGTN
GIGTAIATRCPAQIHGAEHFCEGIQGWTCAAAPIFEPGTQDILGVLDISGPPQTFQRNNLLLAVSVARQIEMALSHSALG
ERLRLLEHCMNRLSLADAAGMVAIDRQGRLIHSAGRVPLPVGVGERLPGFRPHADLEEWAAHLPEGLRPEWLHPVVAGGR
TVGAVVLVPGRGVRNSPVARLAEQSSEADPRRSCFDNILGRSPAMREATDLGRRLATKRVPVLVEGETGVGKELFARALH
GGEHLGGPFITYNCGAASKELIAADLFGHVRGAFTGATNDGRPGRFELANGGTLCLDEIGEMPLDLQPVLLRALEEGIVY
RLGDTQPRRVDVRLIAMTNRNLREEVAAGRFRRDLYYRIGVTRLRIPPLRERDGDIPLLASHFCTQLAERHGVPRREFGP
EVLDALQAYCWPGNVRELRNVVESLLLMDSTPQVRVDELPEEILASVPQAARPAAEGAEPECPSLEAAERRAIQKAVINF
QGNLAQAARLLGISRSTLYRKVERYALEDFVRAAGGNLEGEGGAGD
>Mature_686_residues
MRELSYRKSGVRFSAELRPNPAAQCSGRELVSIDRATYAAWERFVTGEALPPSTIESPVLDSWRRSRDAGVNPVGRAAPV
AARGDDMELLRRRHRELMAAASNLFAHTGDLLAGSHSIMLLTSPEGVVLDAAGDAATLDAARDIHLMTGGNWCEAVVGTN
GIGTAIATRCPAQIHGAEHFCEGIQGWTCAAAPIFEPGTQDILGVLDISGPPQTFQRNNLLLAVSVARQIEMALSHSALG
ERLRLLEHCMNRLSLADAAGMVAIDRQGRLIHSAGRVPLPVGVGERLPGFRPHADLEEWAAHLPEGLRPEWLHPVVAGGR
TVGAVVLVPGRGVRNSPVARLAEQSSEADPRRSCFDNILGRSPAMREATDLGRRLATKRVPVLVEGETGVGKELFARALH
GGEHLGGPFITYNCGAASKELIAADLFGHVRGAFTGATNDGRPGRFELANGGTLCLDEIGEMPLDLQPVLLRALEEGIVY
RLGDTQPRRVDVRLIAMTNRNLREEVAAGRFRRDLYYRIGVTRLRIPPLRERDGDIPLLASHFCTQLAERHGVPRREFGP
EVLDALQAYCWPGNVRELRNVVESLLLMDSTPQVRVDELPEEILASVPQAARPAAEGAEPECPSLEAAERRAIQKAVINF
QGNLAQAARLLGISRSTLYRKVERYALEDFVRAAGGNLEGEGGAGD

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=315, Percent_Identity=42.5396825396825, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=42.3076923076923, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=43.8311688311688, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1788905, Length=335, Percent_Identity=41.4925373134328, Blast_Score=229, Evalue=6e-61,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=42.7710843373494, Blast_Score=226, Evalue=5e-60,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=39.6923076923077, Blast_Score=219, Evalue=6e-58,
Organism=Escherichia coli, GI1789233, Length=336, Percent_Identity=38.6904761904762, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789087, Length=338, Percent_Identity=42.0118343195266, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082117, Length=565, Percent_Identity=30.4424778761062, Blast_Score=207, Evalue=3e-54,
Organism=Escherichia coli, GI87081858, Length=615, Percent_Identity=26.5040650406504, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=36.1370716510903, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI87081872, Length=310, Percent_Identity=38.0645161290323, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1789828, Length=309, Percent_Identity=35.2750809061489, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74212; Mature: 74212

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELSYRKSGVRFSAELRPNPAAQCSGRELVSIDRATYAAWERFVTGEALPPSTIESPVL
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DSWRRSRDAGVNPVGRAAPVAARGDDMELLRRRHRELMAAASNLFAHTGDLLAGSHSIML
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEE
LTSPEGVVLDAAGDAATLDAARDIHLMTGGNWCEAVVGTNGIGTAIATRCPAQIHGAEHF
EECCCCEEEECCCCCCCHHCCCCEEEEECCCHHHHHHCCCCCCHHHHHCCCHHHCCHHHH
CEGIQGWTCAAAPIFEPGTQDILGVLDISGPPQTFQRNNLLLAVSVARQIEMALSHSALG
HHCCCCCEEECCCCCCCCHHHHEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ERLRLLEHCMNRLSLADAAGMVAIDRQGRLIHSAGRVPLPVGVGERLPGFRPHADLEEWA
HHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHH
AHLPEGLRPEWLHPVVAGGRTVGAVVLVPGRGVRNSPVARLAEQSSEADPRRSCFDNILG
HHCCCCCCCHHCCHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHC
RSPAMREATDLGRRLATKRVPVLVEGETGVGKELFARALHGGEHLGGPFITYNCGAASKE
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHH
LIAADLFGHVRGAFTGATNDGRPGRFELANGGTLCLDEIGEMPLDLQPVLLRALEEGIVY
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEHHHHCCCCCCHHHHHHHHHHHCCEE
RLGDTQPRRVDVRLIAMTNRNLREEVAAGRFRRDLYYRIGVTRLRIPPLRERDGDIPLLA
EECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHH
SHFCTQLAERHGVPRREFGPEVLDALQAYCWPGNVRELRNVVESLLLMDSTPQVRVDELP
HHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
EEILASVPQAARPAAEGAEPECPSLEAAERRAIQKAVINFQGNLAQAARLLGISRSTLYR
HHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHH
KVERYALEDFVRAAGGNLEGEGGAGD
HHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRELSYRKSGVRFSAELRPNPAAQCSGRELVSIDRATYAAWERFVTGEALPPSTIESPVL
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DSWRRSRDAGVNPVGRAAPVAARGDDMELLRRRHRELMAAASNLFAHTGDLLAGSHSIML
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEE
LTSPEGVVLDAAGDAATLDAARDIHLMTGGNWCEAVVGTNGIGTAIATRCPAQIHGAEHF
EECCCCEEEECCCCCCCHHCCCCEEEEECCCHHHHHHCCCCCCHHHHHCCCHHHCCHHHH
CEGIQGWTCAAAPIFEPGTQDILGVLDISGPPQTFQRNNLLLAVSVARQIEMALSHSALG
HHCCCCCEEECCCCCCCCHHHHEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ERLRLLEHCMNRLSLADAAGMVAIDRQGRLIHSAGRVPLPVGVGERLPGFRPHADLEEWA
HHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHH
AHLPEGLRPEWLHPVVAGGRTVGAVVLVPGRGVRNSPVARLAEQSSEADPRRSCFDNILG
HHCCCCCCCHHCCHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHC
RSPAMREATDLGRRLATKRVPVLVEGETGVGKELFARALHGGEHLGGPFITYNCGAASKE
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHH
LIAADLFGHVRGAFTGATNDGRPGRFELANGGTLCLDEIGEMPLDLQPVLLRALEEGIVY
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEHHHHCCCCCCHHHHHHHHHHHCCEE
RLGDTQPRRVDVRLIAMTNRNLREEVAAGRFRRDLYYRIGVTRLRIPPLRERDGDIPLLA
EECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHH
SHFCTQLAERHGVPRREFGPEVLDALQAYCWPGNVRELRNVVESLLLMDSTPQVRVDELP
HHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
EEILASVPQAARPAAEGAEPECPSLEAAERRAIQKAVINFQGNLAQAARLLGISRSTLYR
HHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHH
KVERYALEDFVRAAGGNLEGEGGAGD
HHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA