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The map label for this gene is trpB [H]

Identifier: 119897338

GI number: 119897338

Start: 1126595

End: 1127848

Strand: Direct

Name: trpB [H]

Synonym: azo1047

Alternate gene names: 119897338

Gene position: 1126595-1127848 (Clockwise)

Preceding gene: 119897337

Following gene: 119897339

Centisome position: 25.74

GC content: 66.83

Gene sequence:

>1254_bases
ATGCGGCCAGGATCGCCGCATTCGTTGCCGGAGTTCGACATGCAGATGGCTGACACGCCTTACCACTATCCCGACGCCCG
CGGCCATTTCGGCCGGCACGGCGGCGTCTTCGTCGCCGAAACGCTGATGCCGGCCCTCGACGAGCTGCGCGAGGCCTATG
CCCGCTACAGCCAGGATCCCGAGTTCATCGCGGAGTTCCAGTACGAACTCAAGCACTACGTCGGCCGGCCCAGTCCGATC
TACCACGCCAAGCGCTGGTCGGGCATCCTCGGCGGTGCGCAGGTCTATCTGAAGCGCGAAGACCTCAATCACACCGGCGC
GCACAAGGTTAACAACTGCATCGGCCAGGCGCTGCTCGCCCGCCGCATGGGCAAGCCGCGGGTGATTGCCGAAACCGGCG
CCGGCCAGCACGGCGTCGCCACCGCCACCGTCGCTGCCCGCTACGGCATGGAGTGCGTGGTCTATATGGGTGCCGAGGAC
GTCAAGCGCCAAGCCGCCAACGTCTATCGCATGAAACTGCTCGGCGCCACCGTGGTGCCGGTCGAGTCCGGCTCCAAGAC
CCTGAAGGACGCGCTCAACGAAGCCATGCGCGACTGGGTGACGAACGTTGCCGATACCTTCTACATCATCGGCACCGTGG
CGGGGCCGCACCCCTACCCGATGATGGTGCGCGACTTCCAGGCGGTGATCGGCGACGAGTGCAAGGTGCAGATGCCGGAA
CTGGTCGGCCGTCAGCCCGATCAGGTCATCGCCTGCGTGGGCGGCGGTTCGAACGCGATGGGTATCTTCTACCCCTACCT
CGATGTGCCCGGCGTCAAGCTGGTCGGCGTCGAGGCGGCAGGCGAGGGCCTGCAGACCGGCCGTCACGCCGCTCCGCTGA
CGGCGAACGCGCCGGTGGGCGTGCTGCACGGCAACCGCACCTACCTGATGCAGGACGAGGACGGCCAGATCATCGAAACG
CACTCGATCTCGGCCGGTCTCGACTACCCCGGCGTCGGCCCCGAACATGCCTGGCTGAAGGATGACGGGCGCGCCGAGTA
CGTTGCCGTGACCGACAGCGAGGCACTGCAGGCCTTCCACGACCTGTGCCGGTTCGAGGGGATCATCCCGGCGCTGGAGT
CCTCGCACGCGCTGGCGTACGCCGCCAAGATCGCCCCCACCCTGCCGAAGGATCACGTCCTGCTGGTCAATCTCTCCGGG
CGTGGCGACAAGGACATGCACACCGTCGCCGAACGCTCCGGCATCCAGTTCTGA

Upstream 100 bases:

>100_bases
GGCGGCCTGAATCCGTCCAACGTGGAAGAGGCGGTGCGCCGCGTCCGCCCTTGGGCGGTCGACGTGTCGAGCGGCGTCGA
GGTGGCCAAGGGGATCAAGG

Downstream 100 bases:

>100_bases
ACCCGTAGCGGGCCGTCCCGGCCCGCCGCTGCCGAATCCGACATGTCGAAAATCCAGACCACTTTCCAGCGCCTTCAGGC
CCAGGGCCGCAAGGCGCTGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MRPGSPHSLPEFDMQMADTPYHYPDARGHFGRHGGVFVAETLMPALDELREAYARYSQDPEFIAEFQYELKHYVGRPSPI
YHAKRWSGILGGAQVYLKREDLNHTGAHKVNNCIGQALLARRMGKPRVIAETGAGQHGVATATVAARYGMECVVYMGAED
VKRQAANVYRMKLLGATVVPVESGSKTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAVIGDECKVQMPE
LVGRQPDQVIACVGGGSNAMGIFYPYLDVPGVKLVGVEAAGEGLQTGRHAAPLTANAPVGVLHGNRTYLMQDEDGQIIET
HSISAGLDYPGVGPEHAWLKDDGRAEYVAVTDSEALQAFHDLCRFEGIIPALESSHALAYAAKIAPTLPKDHVLLVNLSG
RGDKDMHTVAERSGIQF

Sequences:

>Translated_417_residues
MRPGSPHSLPEFDMQMADTPYHYPDARGHFGRHGGVFVAETLMPALDELREAYARYSQDPEFIAEFQYELKHYVGRPSPI
YHAKRWSGILGGAQVYLKREDLNHTGAHKVNNCIGQALLARRMGKPRVIAETGAGQHGVATATVAARYGMECVVYMGAED
VKRQAANVYRMKLLGATVVPVESGSKTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAVIGDECKVQMPE
LVGRQPDQVIACVGGGSNAMGIFYPYLDVPGVKLVGVEAAGEGLQTGRHAAPLTANAPVGVLHGNRTYLMQDEDGQIIET
HSISAGLDYPGVGPEHAWLKDDGRAEYVAVTDSEALQAFHDLCRFEGIIPALESSHALAYAAKIAPTLPKDHVLLVNLSG
RGDKDMHTVAERSGIQF
>Mature_417_residues
MRPGSPHSLPEFDMQMADTPYHYPDARGHFGRHGGVFVAETLMPALDELREAYARYSQDPEFIAEFQYELKHYVGRPSPI
YHAKRWSGILGGAQVYLKREDLNHTGAHKVNNCIGQALLARRMGKPRVIAETGAGQHGVATATVAARYGMECVVYMGAED
VKRQAANVYRMKLLGATVVPVESGSKTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAVIGDECKVQMPE
LVGRQPDQVIACVGGGSNAMGIFYPYLDVPGVKLVGVEAAGEGLQTGRHAAPLTANAPVGVLHGNRTYLMQDEDGQIIET
HSISAGLDYPGVGPEHAWLKDDGRAEYVAVTDSEALQAFHDLCRFEGIIPALESSHALAYAAKIAPTLPKDHVLLVNLSG
RGDKDMHTVAERSGIQF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=56.7708333333333, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=55.6135770234987, Blast_Score=441, Evalue=1e-124,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45364; Mature: 45364

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGSPHSLPEFDMQMADTPYHYPDARGHFGRHGGVFVAETLMPALDELREAYARYSQDP
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCH
EFIAEFQYELKHYVGRPSPIYHAKRWSGILGGAQVYLKREDLNHTGAHKVNNCIGQALLA
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
RRMGKPRVIAETGAGQHGVATATVAARYGMECVVYMGAEDVKRQAANVYRMKLLGATVVP
HHCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEE
VESGSKTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAVIGDECKVQMPE
ECCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEECHH
LVGRQPDQVIACVGGGSNAMGIFYPYLDVPGVKLVGVEAAGEGLQTGRHAAPLTANAPVG
HHCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEECCCCCCHHCCCCCCCEECCCCEE
VLHGNRTYLMQDEDGQIIETHSISAGLDYPGVGPEHAWLKDDGRAEYVAVTDSEALQAFH
EEECCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEEECCHHHHHHHH
DLCRFEGIIPALESSHALAYAAKIAPTLPKDHVLLVNLSGRGDKDMHTVAERSGIQF
HHHHHCCCCHHHCCCCHHEEHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRPGSPHSLPEFDMQMADTPYHYPDARGHFGRHGGVFVAETLMPALDELREAYARYSQDP
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCH
EFIAEFQYELKHYVGRPSPIYHAKRWSGILGGAQVYLKREDLNHTGAHKVNNCIGQALLA
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
RRMGKPRVIAETGAGQHGVATATVAARYGMECVVYMGAEDVKRQAANVYRMKLLGATVVP
HHCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEE
VESGSKTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAVIGDECKVQMPE
ECCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEECHH
LVGRQPDQVIACVGGGSNAMGIFYPYLDVPGVKLVGVEAAGEGLQTGRHAAPLTANAPVG
HHCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEECCCCCCHHCCCCCCCEECCCCEE
VLHGNRTYLMQDEDGQIIETHSISAGLDYPGVGPEHAWLKDDGRAEYVAVTDSEALQAFH
EEECCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEEECCHHHHHHHH
DLCRFEGIIPALESSHALAYAAKIAPTLPKDHVLLVNLSGRGDKDMHTVAERSGIQF
HHHHHCCCCHHHCCCCHHEEHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]