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The map label for this gene is trpF [H]

Identifier: 119897337

GI number: 119897337

Start: 1126024

End: 1126647

Strand: Direct

Name: trpF [H]

Synonym: azo1046

Alternate gene names: 119897337

Gene position: 1126024-1126647 (Clockwise)

Preceding gene: 119897336

Following gene: 119897338

Centisome position: 25.73

GC content: 67.31

Gene sequence:

>624_bases
ATGTCCCGTACCCGTATCAAGATTTGTGGCCTGACCCGGCCGGATGACGTGCGCGCGGCCGTCGATGCGGGCGCGGACGC
GATCGGCTTCGTCTTCTATCCGCCCAGCCCACGTGCGGTCGATTTCGGCCGTGCGGCCGAGCTTGCAGCGCTGCTCCCAC
CCTTTGTCACCGCAGTCGGACTGTTCGTCAACCCGACGCGCGAGTTCGTCGCCGCCGCGTGTGCCGAAGTGCCGCTGCAA
CTGTTGCAGTTTCACGGCGACGAGACGGAGGCGGAGTGCGCTTCCCATGGTCGGCCGTGGATCAAGGCTGCGCGGGTCCG
CGCGGGGACCGATCTGGTAGAATTCTGCGCTTCCCATGCCCGCGCCCGCGGCATCCTGCTCGACGCCTTCGTCGACGGCT
ACGGCGGCGGCGGGAAAACATTCGATTGGTCCCTGATTCCTCCCCGGCTCGGGCGGCCCCTGATTCTTTCCGGCGGCCTG
AATCCGTCCAACGTGGAAGAGGCGGTGCGCCGCGTCCGCCCTTGGGCGGTCGACGTGTCGAGCGGCGTCGAGGTGGCCAA
GGGGATCAAGGATGCGGCCAGGATCGCCGCATTCGTTGCCGGAGTTCGACATGCAGATGGCTGA

Upstream 100 bases:

>100_bases
ACCCGACGGCCTTTATCTGTGCGGCGTCAGCTATCCGGGCAACTGGTCGCTGCCTGACGATGGGCGTATCATCGCGCTGC
CCCGGATTCCCCTCGTCTGA

Downstream 100 bases:

>100_bases
CACGCCTTACCACTATCCCGACGCCCGCGGCCATTTCGGCCGGCACGGCGGCGTCTTCGTCGCCGAAACGCTGATGCCGG
CCCTCGACGAGCTGCGCGAG

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSRTRIKICGLTRPDDVRAAVDAGADAIGFVFYPPSPRAVDFGRAAELAALLPPFVTAVGLFVNPTREFVAAACAEVPLQ
LLQFHGDETEAECASHGRPWIKAARVRAGTDLVEFCASHARARGILLDAFVDGYGGGGKTFDWSLIPPRLGRPLILSGGL
NPSNVEEAVRRVRPWAVDVSSGVEVAKGIKDAARIAAFVAGVRHADG

Sequences:

>Translated_207_residues
MSRTRIKICGLTRPDDVRAAVDAGADAIGFVFYPPSPRAVDFGRAAELAALLPPFVTAVGLFVNPTREFVAAACAEVPLQ
LLQFHGDETEAECASHGRPWIKAARVRAGTDLVEFCASHARARGILLDAFVDGYGGGGKTFDWSLIPPRLGRPLILSGGL
NPSNVEEAVRRVRPWAVDVSSGVEVAKGIKDAARIAAFVAGVRHADG
>Mature_206_residues
SRTRIKICGLTRPDDVRAAVDAGADAIGFVFYPPSPRAVDFGRAAELAALLPPFVTAVGLFVNPTREFVAAACAEVPLQL
LQFHGDETEAECASHGRPWIKAARVRAGTDLVEFCASHARARGILLDAFVDGYGGGGKTFDWSLIPPRLGRPLILSGGLN
PSNVEEAVRRVRPWAVDVSSGVEVAKGIKDAARIAAFVAGVRHADG

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=206, Percent_Identity=33.9805825242718, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320210, Length=213, Percent_Identity=31.4553990610329, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 21914; Mature: 21783

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTRIKICGLTRPDDVRAAVDAGADAIGFVFYPPSPRAVDFGRAAELAALLPPFVTAVG
CCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LFVNPTREFVAAACAEVPLQLLQFHGDETEAECASHGRPWIKAARVRAGTDLVEFCASHA
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH
RARGILLDAFVDGYGGGGKTFDWSLIPPRLGRPLILSGGLNPSNVEEAVRRVRPWAVDVS
HHCCEEEEEHHCCCCCCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECC
SGVEVAKGIKDAARIAAFVAGVRHADG
CCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRTRIKICGLTRPDDVRAAVDAGADAIGFVFYPPSPRAVDFGRAAELAALLPPFVTAVG
CCCEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LFVNPTREFVAAACAEVPLQLLQFHGDETEAECASHGRPWIKAARVRAGTDLVEFCASHA
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH
RARGILLDAFVDGYGGGGKTFDWSLIPPRLGRPLILSGGLNPSNVEEAVRRVRPWAVDVS
HHCCEEEEEHHCCCCCCCCEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECC
SGVEVAKGIKDAARIAAFVAGVRHADG
CCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA