Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 119897333

GI number: 119897333

Start: 1120327

End: 1121427

Strand: Direct

Name: asd [H]

Synonym: azo1042

Alternate gene names: 119897333

Gene position: 1120327-1121427 (Clockwise)

Preceding gene: 119897332

Following gene: 119897334

Centisome position: 25.6

GC content: 66.39

Gene sequence:

>1101_bases
ATGGTCGGTTCCGTGCTGATGCAGCGCATGGTGGACGAGGGCGATTTCGCCCATATCGAGCCGGTGTATTTCTCCACCTC
GGCGGCCGGCGGCAAGGCCCCGGTGTTCGGCGGCAAGGAGGCGGCGCTGCCGCTTCAGGATGCGACCAGCATCGACGCGC
TGAAGGCCTGCGACATCATCATCACCTGCCAGGGCGGCGACTACACCAAGGAAGTCTTCCCCAAGCTGCGTGCGTCCGGC
TGGGACGGCCACTGGATCGACGCGGCCTCGGCGCTGCGCATGGCGGATGACGCGGTCATCATCCTCGATCCGGTCAACAT
GCACGTGATCAAGGATGCGCTCGCCAAGGGCGGCAAGAACTGGATCGGCGGCAACTGTACGGTGTCGCTGATGCTGATGG
GCCTTGGCGGTCTCTTCAAGCACGACCTGGTCGAGTGGGTGTCGGCGATGACCTACCAGGCTGCCTCCGGCGCCGGTGCG
CAGAACATGCGCGAGCTGATCGCGCAGATGGGCACCATCCACGCTTCGGTGGCCGACCTGCTGGCCGACCCGGCTTCGGC
CATTCTCGACATCGACCGCAAGGTCGCCGAGACCATCCGCTCGGATTCGTTCCCGAAGAAGAACTTCCGCAACACCCCGC
TCGCCGGCAGCCTGATCCCGTGGATCGACGTGCCCGTCGACGGCGGCCAGTCCAAGGAAGAGTGGAAGGGCGGCGCCGAG
TGCAACAAGATCCTCGGCAAGCCGGCGTTCCGCAGCCAGGGCAGCATCCCGATCGACGGCCTGTGCGTGCGCATCGGCGC
GATGCGCTGCCACTCGCAGGGCCTGACCATCAAGCTGAAGAAGGACGTGCCGCTCGACGAGGTCACCGAGATCATCGCCA
CCGCCAACGACTGGGTGAAGGTCGTGCCCAACGAGCGCGAGATCAGCGAACGCGAACTGACCCCGGCGGCGGTGACGGGT
ACCTTGACGGTGCCGGTCGGCCGCCTGCACAAGCTGGCGATGGGGCCTGACTACCTTGGCGCCTTCACCGTGGGTGACCA
GTTGCTGTGGGGCGCGGCCGAGCCCCTGCGCCGCATGTTGCGCATCCTGCTCGATGCCTAA

Upstream 100 bases:

>100_bases
GTGCTGGCGGCGCTCTGAGCGAGCGTTGCCGGGCGGCATGTAAGGTTTGTTGATTCGAGGTGATGTGATGAAGCGAGTAG
GTCTGGTTGGCTGGCGCGGC

Downstream 100 bases:

>100_bases
GCCTTTGGGCGTATCGAACAAAAGGGCTGGGCGGCGTCTGCCGCCCGGCCTTTTTTTCGACGAACGCCCGCCGTTGTTTG
CTCCTCGGGGAGAAACTCCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MVGSVLMQRMVDEGDFAHIEPVYFSTSAAGGKAPVFGGKEAALPLQDATSIDALKACDIIITCQGGDYTKEVFPKLRASG
WDGHWIDAASALRMADDAVIILDPVNMHVIKDALAKGGKNWIGGNCTVSLMLMGLGGLFKHDLVEWVSAMTYQAASGAGA
QNMRELIAQMGTIHASVADLLADPASAILDIDRKVAETIRSDSFPKKNFRNTPLAGSLIPWIDVPVDGGQSKEEWKGGAE
CNKILGKPAFRSQGSIPIDGLCVRIGAMRCHSQGLTIKLKKDVPLDEVTEIIATANDWVKVVPNEREISERELTPAAVTG
TLTVPVGRLHKLAMGPDYLGAFTVGDQLLWGAAEPLRRMLRILLDA

Sequences:

>Translated_366_residues
MVGSVLMQRMVDEGDFAHIEPVYFSTSAAGGKAPVFGGKEAALPLQDATSIDALKACDIIITCQGGDYTKEVFPKLRASG
WDGHWIDAASALRMADDAVIILDPVNMHVIKDALAKGGKNWIGGNCTVSLMLMGLGGLFKHDLVEWVSAMTYQAASGAGA
QNMRELIAQMGTIHASVADLLADPASAILDIDRKVAETIRSDSFPKKNFRNTPLAGSLIPWIDVPVDGGQSKEEWKGGAE
CNKILGKPAFRSQGSIPIDGLCVRIGAMRCHSQGLTIKLKKDVPLDEVTEIIATANDWVKVVPNEREISERELTPAAVTG
TLTVPVGRLHKLAMGPDYLGAFTVGDQLLWGAAEPLRRMLRILLDA
>Mature_366_residues
MVGSVLMQRMVDEGDFAHIEPVYFSTSAAGGKAPVFGGKEAALPLQDATSIDALKACDIIITCQGGDYTKEVFPKLRASG
WDGHWIDAASALRMADDAVIILDPVNMHVIKDALAKGGKNWIGGNCTVSLMLMGLGGLFKHDLVEWVSAMTYQAASGAGA
QNMRELIAQMGTIHASVADLLADPASAILDIDRKVAETIRSDSFPKKNFRNTPLAGSLIPWIDVPVDGGQSKEEWKGGAE
CNKILGKPAFRSQGSIPIDGLCVRIGAMRCHSQGLTIKLKKDVPLDEVTEIIATANDWVKVVPNEREISERELTPAAVTG
TLTVPVGRLHKLAMGPDYLGAFTVGDQLLWGAAEPLRRMLRILLDA

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=363, Percent_Identity=67.4931129476584, Blast_Score=493, Evalue=1e-141,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39212; Mature: 39212

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGSVLMQRMVDEGDFAHIEPVYFSTSAAGGKAPVFGGKEAALPLQDATSIDALKACDII
CHHHHHHHHHHCCCCCCEECEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEE
ITCQGGDYTKEVFPKLRASGWDGHWIDAASALRMADDAVIILDPVNMHVIKDALAKGGKN
EEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCC
WIGGNCTVSLMLMGLGGLFKHDLVEWVSAMTYQAASGAGAQNMRELIAQMGTIHASVADL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LADPASAILDIDRKVAETIRSDSFPKKNFRNTPLAGSLIPWIDVPVDGGQSKEEWKGGAE
HHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHCCCHH
CNKILGKPAFRSQGSIPIDGLCVRIGAMRCHSQGLTIKLKKDVPLDEVTEIIATANDWVK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCEE
VVPNEREISERELTPAAVTGTLTVPVGRLHKLAMGPDYLGAFTVGDQLLWGAAEPLRRML
ECCCCCCCHHHCCCCHHEEEEEEECHHHHHHHHCCCCCCEEEHHCCHHHHCCHHHHHHHH
RILLDA
HHHHCC
>Mature Secondary Structure
MVGSVLMQRMVDEGDFAHIEPVYFSTSAAGGKAPVFGGKEAALPLQDATSIDALKACDII
CHHHHHHHHHHCCCCCCEECEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEE
ITCQGGDYTKEVFPKLRASGWDGHWIDAASALRMADDAVIILDPVNMHVIKDALAKGGKN
EEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCC
WIGGNCTVSLMLMGLGGLFKHDLVEWVSAMTYQAASGAGAQNMRELIAQMGTIHASVADL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LADPASAILDIDRKVAETIRSDSFPKKNFRNTPLAGSLIPWIDVPVDGGQSKEEWKGGAE
HHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHCCCHH
CNKILGKPAFRSQGSIPIDGLCVRIGAMRCHSQGLTIKLKKDVPLDEVTEIIATANDWVK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCEE
VVPNEREISERELTPAAVTGTLTVPVGRLHKLAMGPDYLGAFTVGDQLLWGAAEPLRRML
ECCCCCCCHHHCCCCHHEEEEEEECHHHHHHHHCCCCCCEEEHHCCHHHHCCHHHHHHHH
RILLDA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9084174; 10984043 [H]