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The map label for this gene is gufA [H]

Identifier: 119897246

GI number: 119897246

Start: 1026770

End: 1027678

Strand: Reverse

Name: gufA [H]

Synonym: azo0955

Alternate gene names: 119897246

Gene position: 1027678-1026770 (Counterclockwise)

Preceding gene: 119897247

Following gene: 119897245

Centisome position: 23.48

GC content: 71.51

Gene sequence:

>909_bases
ATGGTTGCCAAGGTCGCCCGTCTGCACTTCATGCCCGCCAGCCCGGCCAGCGCAGCGCGCGCACTCGCCGGCTGGTTGAT
CGCCCTGACCGGTCTGGCGCTGCTGGCCACCCGCCTCGCCGGAGAAATCGGCGGCGGCGCGATCGGCGGCCCGGTCGGCG
ACGCGCTTGCAGGTGGCGCCATGTCCGCAGCAGCGACCGCGCTCGGCGCCCTTCCCTTGCTCGTGATGCGGCGCATCGGC
GCCGGCGTGCAAGGATTGCTGCTCGGCTTCGGCGCCGGCGTGATGCTTGCCGCAAGCGTGTTCTCGCTGTTGCTCCCGGC
CTTCGATGCGGCCCATGCGCTCGGAACCACCGGTCCCGCCGCGGTCGGCGTCGTGGCGGCGGGCCTCGCGCTCGGCGCGG
CCCTGCTCCTCGTCATGGACCGCGCCCTGCCTCACTCGCACGCGCCCGACGGCACGCGGAGCGCCACCGCGGTATGGCTC
TTCGTGTTTGCGATCGCGGTGCACAACATTCCTGAAGGGCTTGCGATCGGCGTCGCCACCGGCATGAATGTCACCGAGGC
GGGCAGCGCGAATGCGGTCGCCACCGGGATCTCGCTGCAGAACGTGCCGGAAGGCCTGATCGTGGCGATTGCGCTGGCCG
CCGCCGGCTACGGCCGCCTGTTCGCGTTCGCGGTCGCGGCGATTTCAGGCCTCATCGAACCAGTCGCCGCAGTGGCCGGC
TCCATGCTCGTCTCGACCGCCACCGCGCTGCTCCCGTGGGGTCTCGCCGGCGCAGCGGGGGCGATGTTGTTCGTGGTCAG
CCACGAGATCATCCCCGAGTCGCACCGGCGCGGGCACGAAACGCTCGCCACCGCGGGCCTGGTGGCCGGCTTCATCGCGA
TGTTGATGATGGATCGCCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
GATACCTATCGAATAATTAAAATCATTCAATTGGAACTATAAATACCGGAAAGCCATAGTCGACCTATCGGAAGCGTCGC
TTCACACCCCGGAGTCGAAC

Downstream 100 bases:

>100_bases
AACGCCGCGCGCAACAAAAAGGCGCCCCGCAAGGGCGCCCTTTTCATGTGTTCAGGGTGGCGAGCCTGACCCCCGGCACT
TGCAGGGAACGGCTGTGGCT

Product: putative cation transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVAKVARLHFMPASPASAARALAGWLIALTGLALLATRLAGEIGGGAIGGPVGDALAGGAMSAAATALGALPLLVMRRIG
AGVQGLLLGFGAGVMLAASVFSLLLPAFDAAHALGTTGPAAVGVVAAGLALGAALLLVMDRALPHSHAPDGTRSATAVWL
FVFAIAVHNIPEGLAIGVATGMNVTEAGSANAVATGISLQNVPEGLIVAIALAAAGYGRLFAFAVAAISGLIEPVAAVAG
SMLVSTATALLPWGLAGAAGAMLFVVSHEIIPESHRRGHETLATAGLVAGFIAMLMMDRLLG

Sequences:

>Translated_302_residues
MVAKVARLHFMPASPASAARALAGWLIALTGLALLATRLAGEIGGGAIGGPVGDALAGGAMSAAATALGALPLLVMRRIG
AGVQGLLLGFGAGVMLAASVFSLLLPAFDAAHALGTTGPAAVGVVAAGLALGAALLLVMDRALPHSHAPDGTRSATAVWL
FVFAIAVHNIPEGLAIGVATGMNVTEAGSANAVATGISLQNVPEGLIVAIALAAAGYGRLFAFAVAAISGLIEPVAAVAG
SMLVSTATALLPWGLAGAAGAMLFVVSHEIIPESHRRGHETLATAGLVAGFIAMLMMDRLLG
>Mature_302_residues
MVAKVARLHFMPASPASAARALAGWLIALTGLALLATRLAGEIGGGAIGGPVGDALAGGAMSAAATALGALPLLVMRRIG
AGVQGLLLGFGAGVMLAASVFSLLLPAFDAAHALGTTGPAAVGVVAAGLALGAALLLVMDRALPHSHAPDGTRSATAVWL
FVFAIAVHNIPEGLAIGVATGMNVTEAGSANAVATGISLQNVPEGLIVAIALAAAGYGRLFAFAVAAISGLIEPVAAVAG
SMLVSTATALLPWGLAGAAGAMLFVVSHEIIPESHRRGHETLATAGLVAGFIAMLMMDRLLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=159, Percent_Identity=42.1383647798742, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI229577418, Length=159, Percent_Identity=42.1383647798742, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17507805, Length=157, Percent_Identity=45.859872611465, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24652846, Length=158, Percent_Identity=42.4050632911392, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29516; Mature: 29516

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKVARLHFMPASPASAARALAGWLIALTGLALLATRLAGEIGGGAIGGPVGDALAGGA
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCHH
MSAAATALGALPLLVMRRIGAGVQGLLLGFGAGVMLAASVFSLLLPAFDAAHALGTTGPA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AVGVVAAGLALGAALLLVMDRALPHSHAPDGTRSATAVWLFVFAIAVHNIPEGLAIGVAT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHC
GMNVTEAGSANAVATGISLQNVPEGLIVAIALAAAGYGRLFAFAVAAISGLIEPVAAVAG
CCCCCCCCCCCHHEECCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLVSTATALLPWGLAGAAGAMLFVVSHEIIPESHRRGHETLATAGLVAGFIAMLMMDRL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LG
CC
>Mature Secondary Structure
MVAKVARLHFMPASPASAARALAGWLIALTGLALLATRLAGEIGGGAIGGPVGDALAGGA
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCHH
MSAAATALGALPLLVMRRIGAGVQGLLLGFGAGVMLAASVFSLLLPAFDAAHALGTTGPA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AVGVVAAGLALGAALLLVMDRALPHSHAPDGTRSATAVWLFVFAIAVHNIPEGLAIGVAT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHC
GMNVTEAGSANAVATGISLQNVPEGLIVAIALAAAGYGRLFAFAVAAISGLIEPVAAVAG
CCCCCCCCCCCHHEECCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLVSTATALLPWGLAGAAGAMLFVVSHEIIPESHRRGHETLATAGLVAGFIAMLMMDRL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]