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The map label for this gene is cfa1 [H]

Identifier: 119897247

GI number: 119897247

Start: 1027781

End: 1029013

Strand: Reverse

Name: cfa1 [H]

Synonym: azo0956

Alternate gene names: 119897247

Gene position: 1029013-1027781 (Counterclockwise)

Preceding gene: 119897256

Following gene: 119897246

Centisome position: 23.51

GC content: 68.21

Gene sequence:

>1233_bases
ATGAACTCTGCCGATACAGACCGCGCCGCCTCCCGCCCCGTGGCGCCCCCTGCGTACTCCCGCGCCCACCGTGGCGCCGC
TGCCCGGCGGGGGGGCGACGATGGCGCGCGGCGCGCCTTCGCCGAACTCCTCGCGCTCGCGGACGTCAGCGTGGACGGCG
AGCGGCCCTGGGACATCCAGGTGCATCACCCGGACACCGCCGCCCGCGTGCTCGCGCAGGGCAGCCTGGGGCTGGGTGAA
GCCTATATGGACGGCTGGTGGGATTGTGCCCGGCTCGACGAGTTCTTCCGCCGCGTACTGGGCGCGCATCTGGACGAAAA
GGTCGGCACCACCTCGCTGATGGTCCAGAGCCTGCGCGCGCGCCTGTTCAATCTGCAGAACCTGCGCCGCGCCTGGCATG
TCGGCCAGACCCACTACGACCTCGGCAACGACTTCTTCGAGGCCATGCTCGACCCGCACATGGCCTACACCTGCGGCTAC
TGGGCCAGCGCGGGTTCGCTCGAGGAAGCGCAGCGCGCCAAACTCGACCTGGTCTGCCGCAAGCTCGAACTGCGCCCCGG
CATGCGCCTGCTCGACATCGGCTGCGGATGGGGCAGCCTGATGAAGTTCGCCGCCACGCATTACGGCGTGCAGTGCGTGG
GGCTCACCATCTCGCGCGAGCAGGCCGAATTCGGGCGCGCGCGCTGCGCGGGTTTGCCGGTGGAGTTCCGCCTCGCCGAT
TACCGTGAATTCCGGCCGGCAGAAGGCGAGCACTTCGACCGCTCGGCCTCGCTCGGCATGTTCGAGCACGTCGGCCACAA
GAATCATCCCGCCTATTTCGATGCGGTACGGCGCTGCCTGCCCGATGACGATCCGCAGGCCCTGTTCCTGTTGCACACGA
TCGGCAAGAACCTGCGCCGGATGCCGACCGATCCGTGGATAGACCGCTACATCTTTCCGAACGGCGACCTGCCCACGCTC
GGACAGATCACCGACGCGGCGGAAGACCGCTTCATCATCGAAGACGTCCACAACTTTGGCGCCGACTACGACCGCACGCT
GATGGCCTGGCACGCACGCTTCGAGACCGCCTGGCCCCGCTTCGCCGAACGCTATGGCGAACGCTTCCACCGGATGTGGC
GCTACTACCTGCTCGCCTGTGCCGGCACCTTCCGCGCCCGCACCACCCAGCTGTGGCAGATCGTGATGTCGCCAACGGGC
ACGCCCGGCGGCTATCGGCGCCCGTTGATTTAG

Upstream 100 bases:

>100_bases
GTGCGCCGTTTGCGCGGAAATCGCCGAAGTGTCTTGACCCGGGTGTATGCCGCCGTCGCCCGCCCGGGCCGGACGACGCG
CTTGCGCTAGAGGAGCGTGC

Downstream 100 bases:

>100_bases
CCGATACCTATCGAATAATTAAAATCATTCAATTGGAACTATAAATACCGGAAAGCCATAGTCGACCTATCGGAAGCGTC
GCTTCACACCCCGGAGTCGA

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNSADTDRAASRPVAPPAYSRAHRGAAARRGGDDGARRAFAELLALADVSVDGERPWDIQVHHPDTAARVLAQGSLGLGE
AYMDGWWDCARLDEFFRRVLGAHLDEKVGTTSLMVQSLRARLFNLQNLRRAWHVGQTHYDLGNDFFEAMLDPHMAYTCGY
WASAGSLEEAQRAKLDLVCRKLELRPGMRLLDIGCGWGSLMKFAATHYGVQCVGLTISREQAEFGRARCAGLPVEFRLAD
YREFRPAEGEHFDRSASLGMFEHVGHKNHPAYFDAVRRCLPDDDPQALFLLHTIGKNLRRMPTDPWIDRYIFPNGDLPTL
GQITDAAEDRFIIEDVHNFGADYDRTLMAWHARFETAWPRFAERYGERFHRMWRYYLLACAGTFRARTTQLWQIVMSPTG
TPGGYRRPLI

Sequences:

>Translated_410_residues
MNSADTDRAASRPVAPPAYSRAHRGAAARRGGDDGARRAFAELLALADVSVDGERPWDIQVHHPDTAARVLAQGSLGLGE
AYMDGWWDCARLDEFFRRVLGAHLDEKVGTTSLMVQSLRARLFNLQNLRRAWHVGQTHYDLGNDFFEAMLDPHMAYTCGY
WASAGSLEEAQRAKLDLVCRKLELRPGMRLLDIGCGWGSLMKFAATHYGVQCVGLTISREQAEFGRARCAGLPVEFRLAD
YREFRPAEGEHFDRSASLGMFEHVGHKNHPAYFDAVRRCLPDDDPQALFLLHTIGKNLRRMPTDPWIDRYIFPNGDLPTL
GQITDAAEDRFIIEDVHNFGADYDRTLMAWHARFETAWPRFAERYGERFHRMWRYYLLACAGTFRARTTQLWQIVMSPTG
TPGGYRRPLI
>Mature_410_residues
MNSADTDRAASRPVAPPAYSRAHRGAAARRGGDDGARRAFAELLALADVSVDGERPWDIQVHHPDTAARVLAQGSLGLGE
AYMDGWWDCARLDEFFRRVLGAHLDEKVGTTSLMVQSLRARLFNLQNLRRAWHVGQTHYDLGNDFFEAMLDPHMAYTCGY
WASAGSLEEAQRAKLDLVCRKLELRPGMRLLDIGCGWGSLMKFAATHYGVQCVGLTISREQAEFGRARCAGLPVEFRLAD
YREFRPAEGEHFDRSASLGMFEHVGHKNHPAYFDAVRRCLPDDDPQALFLLHTIGKNLRRMPTDPWIDRYIFPNGDLPTL
GQITDAAEDRFIIEDVHNFGADYDRTLMAWHARFETAWPRFAERYGERFHRMWRYYLLACAGTFRARTTQLWQIVMSPTG
TPGGYRRPLI

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=377, Percent_Identity=54.1114058355438, Blast_Score=412, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI133904226, Length=383, Percent_Identity=29.7650130548303, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 46581; Mature: 46581

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSADTDRAASRPVAPPAYSRAHRGAAARRGGDDGARRAFAELLALADVSVDGERPWDIQ
CCCCCCCHHCCCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
VHHPDTAARVLAQGSLGLGEAYMDGWWDCARLDEFFRRVLGAHLDEKVGTTSLMVQSLRA
EECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLFNLQNLRRAWHVGQTHYDLGNDFFEAMLDPHMAYTCGYWASAGSLEEAQRAKLDLVCR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KLELRPGMRLLDIGCGWGSLMKFAATHYGVQCVGLTISREQAEFGRARCAGLPVEFRLAD
HHHCCCCCEEEEECCCHHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHHCCCCEEEEECC
YREFRPAEGEHFDRSASLGMFEHVGHKNHPAYFDAVRRCLPDDDPQALFLLHTIGKNLRR
HHHCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
MPTDPWIDRYIFPNGDLPTLGQITDAAEDRFIIEDVHNFGADYDRTLMAWHARFETAWPR
CCCCCCCCCEECCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FAERYGERFHRMWRYYLLACAGTFRARTTQLWQIVMSPTGTPGGYRRPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSADTDRAASRPVAPPAYSRAHRGAAARRGGDDGARRAFAELLALADVSVDGERPWDIQ
CCCCCCCHHCCCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
VHHPDTAARVLAQGSLGLGEAYMDGWWDCARLDEFFRRVLGAHLDEKVGTTSLMVQSLRA
EECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLFNLQNLRRAWHVGQTHYDLGNDFFEAMLDPHMAYTCGYWASAGSLEEAQRAKLDLVCR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KLELRPGMRLLDIGCGWGSLMKFAATHYGVQCVGLTISREQAEFGRARCAGLPVEFRLAD
HHHCCCCCEEEEECCCHHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHHCCCCEEEEECC
YREFRPAEGEHFDRSASLGMFEHVGHKNHPAYFDAVRRCLPDDDPQALFLLHTIGKNLRR
HHHCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
MPTDPWIDRYIFPNGDLPTLGQITDAAEDRFIIEDVHNFGADYDRTLMAWHARFETAWPR
CCCCCCCCCEECCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FAERYGERFHRMWRYYLLACAGTFRARTTQLWQIVMSPTGTPGGYRRPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]