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The map label for this gene is hflK [H]

Identifier: 119897225

GI number: 119897225

Start: 1000148

End: 1001389

Strand: Direct

Name: hflK [H]

Synonym: azo0934

Alternate gene names: 119897225

Gene position: 1000148-1001389 (Clockwise)

Preceding gene: 119897224

Following gene: 119897226

Centisome position: 22.86

GC content: 64.41

Gene sequence:

>1242_bases
ATGTCTCTTAACGACCCACGTTGGGGTGGCCAGGGCGGTAACAATGGCGACCGCGGCGACGGCAATCGCGGTGGCAATCA
GGGGCCTCCTGACCTGGAAGAAGTTTGGCGCGACTTCAATCAGCGTCTCTCCGGCATGTTCGGGGGAAAGCGTCAGGGCC
GGGGTTCTGGCGGCGGGGGCGGAGACGGCCCGCAACTACCCAATTTTTCATTTCGGCAGTTCGGTGGTGGCCTCGGTGCC
CTCGTCGCGCTGGTGCTGATCGTGTGGCTGGCGAGCGGGCTTTACACCGTTGACGCCAACCAGCGCGGCGTGGTCCTGCG
TCTTGGCAAGTTCACCGAGACAACCGAGCCCGGCCTGCGCTGGCGCTTGCCCTATCCGTTCGAAACCCATGAGATCGTCG
ACCTCACCGGGGTGCGTACCGTCGAGGTGGGCTATCGCGGATCGGAGCGCAACAAGGTCCTGCGCGAGTCGTTGATGCTC
ACCGACGACGAGAACATCATCAACATCCAGTTCGCCGTTCAGTACGTGCTGAACAGTCCGGAGAATTACGTCTTCAACAA
CCGTTTCCCCGACGAATCCGTCGCGCAGGCGGCCGAGACGGCCATGCGCGAAATCGTCGGCAAGAGCCGGATGGACTTCG
TGCTGTACGAAGGGCGCGAAGAGATTGCCGCGACCGCGCACGAACTGATGCAGCGCATCCTCGATCGCTACCAGACCGGC
ATCCTGATCAGCCGGGTCACGATGCAGAATGCGCAGCCCCCGGAGCAGGTGCAGGCCGCCTTCGACGACGCCGTGAAGGC
GGGTCAGGACAGGGAGCGCCAGAAGAACGAAGGCGAAGCCTACGCGAACGATGTGATTCCACGTGCGCGCGGTACGGCCT
CGCGCCTGATCGAGGAAGCCAACGCCTACCAGGCGCGCGTGGTTGCCAACGCAGAGGGCGAGGCGAGTCGTTTCAGCCAG
ATCCTTGCCGAGTACAAGCGCGCGCCGGACGTGACCCGCGAACGTCTGTACCTCGAAACCATGCAGCAGGTGCTGTCCAG
CACGTCGAAGGTCATGATCGACGCGAAGGGTAACGGCAACCTGCTGTTCCTTCCGCTCGACAAGCTCGTTCAGCAGGCGG
CCGCGGGCACCACAGGCGCGGGTGAGCCGACGGCCTCCGTGCCGCCGCCGTCCCCGTCTTCCGGGTTGCCCGATACCCGG
ACCCGTGAATTGACCCGCAACCGCGACCGGGGAGAACGCTGA

Upstream 100 bases:

>100_bases
AGGCGCTGGCCGAGCTTGCGTGCCGCGACGCGCTGCCCGGTTCCGGTGCGGCAGATCCAGTCGGCAACCAACCTATTCAA
TAGTGCTAACAGGCGTTCTC

Downstream 100 bases:

>100_bases
TGCGCGACAAGCTTTCCGTGATTGCCGGTGTTGTGCTCTTTGCCATCGTGCTGGCGTCGATGTCGCTGTTTACCGTCGAT
CAGCGCCAGTACGCGATCGT

Product: putative Hflk protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSLNDPRWGGQGGNNGDRGDGNRGGNQGPPDLEEVWRDFNQRLSGMFGGKRQGRGSGGGGGDGPQLPNFSFRQFGGGLGA
LVALVLIVWLASGLYTVDANQRGVVLRLGKFTETTEPGLRWRLPYPFETHEIVDLTGVRTVEVGYRGSERNKVLRESLML
TDDENIINIQFAVQYVLNSPENYVFNNRFPDESVAQAAETAMREIVGKSRMDFVLYEGREEIAATAHELMQRILDRYQTG
ILISRVTMQNAQPPEQVQAAFDDAVKAGQDRERQKNEGEAYANDVIPRARGTASRLIEEANAYQARVVANAEGEASRFSQ
ILAEYKRAPDVTRERLYLETMQQVLSSTSKVMIDAKGNGNLLFLPLDKLVQQAAAGTTGAGEPTASVPPPSPSSGLPDTR
TRELTRNRDRGER

Sequences:

>Translated_413_residues
MSLNDPRWGGQGGNNGDRGDGNRGGNQGPPDLEEVWRDFNQRLSGMFGGKRQGRGSGGGGGDGPQLPNFSFRQFGGGLGA
LVALVLIVWLASGLYTVDANQRGVVLRLGKFTETTEPGLRWRLPYPFETHEIVDLTGVRTVEVGYRGSERNKVLRESLML
TDDENIINIQFAVQYVLNSPENYVFNNRFPDESVAQAAETAMREIVGKSRMDFVLYEGREEIAATAHELMQRILDRYQTG
ILISRVTMQNAQPPEQVQAAFDDAVKAGQDRERQKNEGEAYANDVIPRARGTASRLIEEANAYQARVVANAEGEASRFSQ
ILAEYKRAPDVTRERLYLETMQQVLSSTSKVMIDAKGNGNLLFLPLDKLVQQAAAGTTGAGEPTASVPPPSPSSGLPDTR
TRELTRNRDRGER
>Mature_412_residues
SLNDPRWGGQGGNNGDRGDGNRGGNQGPPDLEEVWRDFNQRLSGMFGGKRQGRGSGGGGGDGPQLPNFSFRQFGGGLGAL
VALVLIVWLASGLYTVDANQRGVVLRLGKFTETTEPGLRWRLPYPFETHEIVDLTGVRTVEVGYRGSERNKVLRESLMLT
DDENIINIQFAVQYVLNSPENYVFNNRFPDESVAQAAETAMREIVGKSRMDFVLYEGREEIAATAHELMQRILDRYQTGI
LISRVTMQNAQPPEQVQAAFDDAVKAGQDRERQKNEGEAYANDVIPRARGTASRLIEEANAYQARVVANAEGEASRFSQI
LAEYKRAPDVTRERLYLETMQQVLSSTSKVMIDAKGNGNLLFLPLDKLVQQAAAGTTGAGEPTASVPPPSPSSGLPDTRT
RELTRNRDRGER

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=369, Percent_Identity=40.9214092140921, Blast_Score=245, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 45434; Mature: 45303

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNDPRWGGQGGNNGDRGDGNRGGNQGPPDLEEVWRDFNQRLSGMFGGKRQGRGSGGGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GDGPQLPNFSFRQFGGGLGALVALVLIVWLASGLYTVDANQRGVVLRLGKFTETTEPGLR
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCE
WRLPYPFETHEIVDLTGVRTVEVGYRGSERNKVLRESLMLTDDENIINIQFAVQYVLNSP
EECCCCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
ENYVFNNRFPDESVAQAAETAMREIVGKSRMDFVLYEGREEIAATAHELMQRILDRYQTG
CCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHC
ILISRVTMQNAQPPEQVQAAFDDAVKAGQDRERQKNEGEAYANDVIPRARGTASRLIEEA
HHEEHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
NAYQARVVANAEGEASRFSQILAEYKRAPDVTRERLYLETMQQVLSSTSKVMIDAKGNGN
HHHEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
LLFLPLDKLVQQAAAGTTGAGEPTASVPPPSPSSGLPDTRTRELTRNRDRGER
EEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLNDPRWGGQGGNNGDRGDGNRGGNQGPPDLEEVWRDFNQRLSGMFGGKRQGRGSGGGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GDGPQLPNFSFRQFGGGLGALVALVLIVWLASGLYTVDANQRGVVLRLGKFTETTEPGLR
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCE
WRLPYPFETHEIVDLTGVRTVEVGYRGSERNKVLRESLMLTDDENIINIQFAVQYVLNSP
EECCCCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
ENYVFNNRFPDESVAQAAETAMREIVGKSRMDFVLYEGREEIAATAHELMQRILDRYQTG
CCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHC
ILISRVTMQNAQPPEQVQAAFDDAVKAGQDRERQKNEGEAYANDVIPRARGTASRLIEEA
HHEEHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
NAYQARVVANAEGEASRFSQILAEYKRAPDVTRERLYLETMQQVLSSTSKVMIDAKGNGN
HHHEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
LLFLPLDKLVQQAAAGTTGAGEPTASVPPPSPSSGLPDTRTRELTRNRDRGER
EEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]