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The map label for this gene is dctS [H]

Identifier: 119897209

GI number: 119897209

Start: 983320

End: 985311

Strand: Reverse

Name: dctS [H]

Synonym: azo0918

Alternate gene names: 119897209

Gene position: 985311-983320 (Counterclockwise)

Preceding gene: 119897244

Following gene: 119897208

Centisome position: 22.52

GC content: 68.17

Gene sequence:

>1992_bases
ATGCCCACGCCGCCCCCTCCTCAGCTAGCCGCACCGCCCTCCGAGGAGGGCCGACGCAGCCGCTGGGTTGCGCGCCTTCC
CTACCTCGCCCTCGCGCTGTTCCTGGGCGCCATCGCGGCCCTCGTCTGGCTGACGCGCGAATACGACGAAGAGGAGCAGC
GCGCCACGCTCATCAATGATGCGTTGTGGATGGAGCAGAATCTGCGCTTCCAGCTTGACCGCAATGCAGCACAACTGCAG
CAGATCGCACCCGATTTGCTGCGCACGGAACGGCTTTCCGGCCCCACGGAAGCGCAGTTGCGCCAGCTTCTCAGCCCCGA
CCGCGGCCTCGTCCAGATTCTGTGGCTCGATGCGGAGGGGCGCGTTCGCAATTCGATGCCGCCCCAGTCGGAAGACAAGC
TGATCGGCGAAACCAGCGGCGCGGTGCCCTCCCCGGACATCTCGCGCCTCGCCCGCGCCGTCGGCCGACCCGTGTACGGC
CCCGCCTACCCGGTGCTGGGCGACCAGACGCAGTTCGAAGCCCACGTGCCGGTCTGGGGCGACGAAGGCTTTCTCGGCAC
CGTCGTCGGCGTGTATTCGTTATCCGACCTCGTCGTGCGCGAGCTGCCGTGGTGGTTCTCCGAACGCTACCGGGTTGCAG
TGCTCGACCCCGACGGGCGCGAAGTCGCTTCGAAGTCCAAGGTTGCGCCGCTCGACCCGGGCCGCGCCTACACCATTGCT
TTCGATCCGCCCGGGCACGGCCTGACCCTGCAGATCACGCCCTACAAGGGTGAAACGCGCTGGATTCCGGTGCTGCTGTC
GGCCTCGATGCTGCTGTTCGCGGTCATCATCGTCTGGAGCGTCTGGCAGCTGCGCCGCCAGCTCGCCGCGCGCCAGGCGG
CCGAACAGGCGGTACGCGCCGAATCGGCCTATCGCCGTGCGATGGAGGACTCGCTCATCACCGGGCTGCGCGCCCGCGAT
CTCAGCGGCCGCCTCACCTATGTGAACTCCGCGTTCTGCCGCATGACCGGCTATACGGCAGAAGAACTGGTCGGCTGCAA
GCCGCCCATGCCCTACTGGGACCCCGACCACATCGCCGAGACGCAGAAGCTGCACGAGCAGATCATGGCCGGCGGCACCT
CCCCCGAAGGCGTCGAGGTGCGCCTGCGGCGCCGGAACGGCGAGCGGCTGGACGCGCTGGTGTTCGAGGCGCCGCTGATC
GACGCCCACGGCCGTCACACCGGCTGGATGGGCTCGGTGCTCGACATTACCGAGCAGAAGCGGGCTCGTGAACTCGCGCT
GCAACAGGAAGAACGGCTGCAGGCAACTTCCCGGCTGGTGACGATGGGCGAAATGGCCTCCACGCTCGCCCACGAGCTGA
ACCAGCCGCTCGCGGCGATCGCCAGTTACAACACCGGCTGCCTGAACCGCCTCGAGGCCGACGAATTCGACCGCGACGAA
CTGCGCGACATCCACGAGAAGATCGGCCGTCAGGCGCGCCGCGCCGGCGACATCATCCGCCGCGTGCACGATTTCGTGCG
CCGCGCCGAGCCGCGCCGCGAGGCGCTCGACCTCAACGAGGTGATCCGCGAGGCGCTCGGTCTCGTCGAACCGGACGCGC
GCAAACGCCGCATCCATCTGGTGGCCGACCTCGCCGCCGATCTGCCGGTGGTGCACGCGGACGCGGTGATGATCGAGCAG
ATCATCGTCAACCTGGTGCGCAACGGCATGGATGCCATGCAGGACACGCCGGAGCCGAACCGCAGCCTGCGGATCGGCAC
GCGCAGCGCGGGAGCGGTGGTGACAGTACGGGTAACCGATCACGGCACCGGCATCGACGCCGAGACCGCGCGCCACCTGT
TCCAGCCCTTCTTCACCACCAAGCAGGAGGGGATGGGCATGGGTCTCAACATCTGCCGCTCGATCGCCGAGCTGCACCAC
GGCCGCCTCGGTTTTGAGCCAGCTCCCGACGGCGGTACCATCTTCACCCTCACGCTCCCGGTGGACTCCTGA

Upstream 100 bases:

>100_bases
ATCGCAGCTGCTATTGTGGAAGTCCGCAAGAACCAACTTACGCCAAACAGGTTATGCCATCGCGTCCGCATACTGCGGCG
CAACATGCCCTTTCACGCCG

Downstream 100 bases:

>100_bases
ATGACCCAGGCCTGCGCCCACATCATTGACGACGACGAAGCCATCCGCGACGCGCTGCAATGGTTGTTCAAGACGCGCTC
GGTGAACTGCCGGGCCTGGA

Product: two-component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MPTPPPPQLAAPPSEEGRRSRWVARLPYLALALFLGAIAALVWLTREYDEEEQRATLINDALWMEQNLRFQLDRNAAQLQ
QIAPDLLRTERLSGPTEAQLRQLLSPDRGLVQILWLDAEGRVRNSMPPQSEDKLIGETSGAVPSPDISRLARAVGRPVYG
PAYPVLGDQTQFEAHVPVWGDEGFLGTVVGVYSLSDLVVRELPWWFSERYRVAVLDPDGREVASKSKVAPLDPGRAYTIA
FDPPGHGLTLQITPYKGETRWIPVLLSASMLLFAVIIVWSVWQLRRQLAARQAAEQAVRAESAYRRAMEDSLITGLRARD
LSGRLTYVNSAFCRMTGYTAEELVGCKPPMPYWDPDHIAETQKLHEQIMAGGTSPEGVEVRLRRRNGERLDALVFEAPLI
DAHGRHTGWMGSVLDITEQKRARELALQQEERLQATSRLVTMGEMASTLAHELNQPLAAIASYNTGCLNRLEADEFDRDE
LRDIHEKIGRQARRAGDIIRRVHDFVRRAEPRREALDLNEVIREALGLVEPDARKRRIHLVADLAADLPVVHADAVMIEQ
IIVNLVRNGMDAMQDTPEPNRSLRIGTRSAGAVVTVRVTDHGTGIDAETARHLFQPFFTTKQEGMGMGLNICRSIAELHH
GRLGFEPAPDGGTIFTLTLPVDS

Sequences:

>Translated_663_residues
MPTPPPPQLAAPPSEEGRRSRWVARLPYLALALFLGAIAALVWLTREYDEEEQRATLINDALWMEQNLRFQLDRNAAQLQ
QIAPDLLRTERLSGPTEAQLRQLLSPDRGLVQILWLDAEGRVRNSMPPQSEDKLIGETSGAVPSPDISRLARAVGRPVYG
PAYPVLGDQTQFEAHVPVWGDEGFLGTVVGVYSLSDLVVRELPWWFSERYRVAVLDPDGREVASKSKVAPLDPGRAYTIA
FDPPGHGLTLQITPYKGETRWIPVLLSASMLLFAVIIVWSVWQLRRQLAARQAAEQAVRAESAYRRAMEDSLITGLRARD
LSGRLTYVNSAFCRMTGYTAEELVGCKPPMPYWDPDHIAETQKLHEQIMAGGTSPEGVEVRLRRRNGERLDALVFEAPLI
DAHGRHTGWMGSVLDITEQKRARELALQQEERLQATSRLVTMGEMASTLAHELNQPLAAIASYNTGCLNRLEADEFDRDE
LRDIHEKIGRQARRAGDIIRRVHDFVRRAEPRREALDLNEVIREALGLVEPDARKRRIHLVADLAADLPVVHADAVMIEQ
IIVNLVRNGMDAMQDTPEPNRSLRIGTRSAGAVVTVRVTDHGTGIDAETARHLFQPFFTTKQEGMGMGLNICRSIAELHH
GRLGFEPAPDGGTIFTLTLPVDS
>Mature_662_residues
PTPPPPQLAAPPSEEGRRSRWVARLPYLALALFLGAIAALVWLTREYDEEEQRATLINDALWMEQNLRFQLDRNAAQLQQ
IAPDLLRTERLSGPTEAQLRQLLSPDRGLVQILWLDAEGRVRNSMPPQSEDKLIGETSGAVPSPDISRLARAVGRPVYGP
AYPVLGDQTQFEAHVPVWGDEGFLGTVVGVYSLSDLVVRELPWWFSERYRVAVLDPDGREVASKSKVAPLDPGRAYTIAF
DPPGHGLTLQITPYKGETRWIPVLLSASMLLFAVIIVWSVWQLRRQLAARQAAEQAVRAESAYRRAMEDSLITGLRARDL
SGRLTYVNSAFCRMTGYTAEELVGCKPPMPYWDPDHIAETQKLHEQIMAGGTSPEGVEVRLRRRNGERLDALVFEAPLID
AHGRHTGWMGSVLDITEQKRARELALQQEERLQATSRLVTMGEMASTLAHELNQPLAAIASYNTGCLNRLEADEFDRDEL
RDIHEKIGRQARRAGDIIRRVHDFVRRAEPRREALDLNEVIREALGLVEPDARKRRIHLVADLAADLPVVHADAVMIEQI
IVNLVRNGMDAMQDTPEPNRSLRIGTRSAGAVVTVRVTDHGTGIDAETARHLFQPFFTTKQEGMGMGLNICRSIAELHHG
RLGFEPAPDGGTIFTLTLPVDS

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=368, Percent_Identity=25.8152173913043, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=31.404958677686, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI48994928, Length=388, Percent_Identity=23.9690721649485, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=25.0965250965251, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=153, Percent_Identity=30.0653594771242, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=144, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73969; Mature: 73838

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPPPPQLAAPPSEEGRRSRWVARLPYLALALFLGAIAALVWLTREYDEEEQRATLIND
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALWMEQNLRFQLDRNAAQLQQIAPDLLRTERLSGPTEAQLRQLLSPDRGLVQILWLDAEG
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCCC
RVRNSMPPQSEDKLIGETSGAVPSPDISRLARAVGRPVYGPAYPVLGDQTQFEAHVPVWG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCC
DEGFLGTVVGVYSLSDLVVRELPWWFSERYRVAVLDPDGREVASKSKVAPLDPGRAYTIA
CCCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCHHHHHCCCCCCCCCCCEEEEE
FDPPGHGLTLQITPYKGETRWIPVLLSASMLLFAVIIVWSVWQLRRQLAARQAAEQAVRA
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAYRRAMEDSLITGLRARDLSGRLTYVNSAFCRMTGYTAEELVGCKPPMPYWDPDHIAE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHH
TQKLHEQIMAGGTSPEGVEVRLRRRNGERLDALVFEAPLIDAHGRHTGWMGSVLDITEQK
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
RARELALQQEERLQATSRLVTMGEMASTLAHELNQPLAAIASYNTGCLNRLEADEFDRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHCCCCCCCCHHH
LRDIHEKIGRQARRAGDIIRRVHDFVRRAEPRREALDLNEVIREALGLVEPDARKRRIHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCCHHHHHHH
VADLAADLPVVHADAVMIEQIIVNLVRNGMDAMQDTPEPNRSLRIGTRSAGAVVTVRVTD
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCEEEEEEEEC
HGTGIDAETARHLFQPFFTTKQEGMGMGLNICRSIAELHHGRLGFEPAPDGGTIFTLTLP
CCCCCCHHHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEE
VDS
CCC
>Mature Secondary Structure 
PTPPPPQLAAPPSEEGRRSRWVARLPYLALALFLGAIAALVWLTREYDEEEQRATLIND
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALWMEQNLRFQLDRNAAQLQQIAPDLLRTERLSGPTEAQLRQLLSPDRGLVQILWLDAEG
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCCC
RVRNSMPPQSEDKLIGETSGAVPSPDISRLARAVGRPVYGPAYPVLGDQTQFEAHVPVWG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCC
DEGFLGTVVGVYSLSDLVVRELPWWFSERYRVAVLDPDGREVASKSKVAPLDPGRAYTIA
CCCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCHHHHHCCCCCCCCCCCEEEEE
FDPPGHGLTLQITPYKGETRWIPVLLSASMLLFAVIIVWSVWQLRRQLAARQAAEQAVRA
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAYRRAMEDSLITGLRARDLSGRLTYVNSAFCRMTGYTAEELVGCKPPMPYWDPDHIAE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHH
TQKLHEQIMAGGTSPEGVEVRLRRRNGERLDALVFEAPLIDAHGRHTGWMGSVLDITEQK
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
RARELALQQEERLQATSRLVTMGEMASTLAHELNQPLAAIASYNTGCLNRLEADEFDRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHCCCCCCCCHHH
LRDIHEKIGRQARRAGDIIRRVHDFVRRAEPRREALDLNEVIREALGLVEPDARKRRIHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCCHHHHHHH
VADLAADLPVVHADAVMIEQIIVNLVRNGMDAMQDTPEPNRSLRIGTRSAGAVVTVRVTD
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCEEEEEEEEC
HGTGIDAETARHLFQPFFTTKQEGMGMGLNICRSIAELHHGRLGFEPAPDGGTIFTLTLP
CCCCCCHHHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEE
VDS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]