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The map label for this gene is rosB [H]

Identifier: 119897203

GI number: 119897203

Start: 975796

End: 977517

Strand: Direct

Name: rosB [H]

Synonym: azo0912

Alternate gene names: 119897203

Gene position: 975796-977517 (Clockwise)

Preceding gene: 119897202

Following gene: 119897205

Centisome position: 22.3

GC content: 65.97

Gene sequence:

>1722_bases
ATGCCCCATGACGTCTCGCTGATCGCAACCCTCGCCGTTGGTTTCGGCCTTGCGCTGTTGCTCGGCTTCATTGCCGACCG
CCTGCGCTTGCCGGCCCTCGTCGGATACCTGCTTGCAGGCATCCTGATCGGTCCGGCTACTCCGGGCTTCGTCGCCGACG
TTGGGATCGCGGGGCAACTTGCCGAGATTGGCGTGATGTTGCTGATGTTCGGCGTGGGTTTGCATTTTTCGCTGGAAGAT
CTGCTCGCGGTCCGCCGCATTGCGCTGCCCGGGGCGGTGGTCCAGATGGCGGTGGCAACGCTGCTCGGGATGGGAATGGC
CGCCTTGTGGGGCTGGAATCTGGGGGCGGGGCTGATATTCGGACTCTCGCTTTCCGTGGCCAGCACCGTCGTTTTGTTGA
AGGCGTTGGAGACGCGGGGCATCCTCGAGACCGTGAATGGCCGCATCGCGGTAGGTTGGCTAGTGGTTGAAGACCTCGCG
ATGGTCGTGGTGCTGGTGCTGCTGCCACCCCTCGCCGGTTTGCTCGGCGGTACCGCCGAAGTCGAGCCCTCGCAGCCGCT
GTGGCGCACCGTGGGACTGACCCTGTTGCAGGTTGGCGCTTTCGTGGCCTTGATGCTGCTTGTCGGCCGGCGCGTGTTGC
CCTGGTTGCTGTGGCAGGTGGCCGGTAGCGGGTCGCGCGAACTGTTCACGCTGGGCGTGATTGCCGCTGCGGTCAGCATT
GCGTTCGGCGCGGCGCAGCTCTTCGGCGTGTCCTTTGCGCTCGGTGCCTTCTTCGCCGGCATGGTGATGCGCGAATCGGA
ATTCAGCCACCGCGCGGCGCAGGAGTCGCTGCCGTTGCGGGACGCCTTTGCCGTGCTGTTCTTCGTTTCGGTCGGGATGC
TGTTCGATCCCAGCGTGCTCGTCGAGTATCCGCTGCACGTGCTGGGCGTGGTCGCCGTGATCATCGTAGGCAAGTCGATC
GCCGCCGCTGCGCTCGTGATCGCCTTCCGCTATCCGCTTAACACCGCGCTCACGGTTGCCGCCAGCCTTGCCCAGATCGG
CGAGTTCTCCTTCATCCTGGCCGGCCTTGGCATGGCGCTTGGGCTGTTGCCCGCCGCCGGGCAGAGTCTGATCCTGGCGG
GGGCCTTGATCTCGATCGCAGCCAATCCCTTCGTGTTCGCCACCGTGCGGCCGGCGGGAAAGTGGATGCTCGACAACTGG
AGCGTGGCGCGGCGGCTTGCGCTTCGCGCCGACCCGCTGACGGAATTGCCGATGAGCACCGAGCGGGATTTTCTGGAAGG
GCAGGTGGTACTGGTCGGCTACGGGCGGGTTGGTCGCCGCATTGCCGAGGCCTTGCAGGCGCGAGACATCCCATACGTGG
TGGCGGAGCAGAACCGCGAGCGGGTAGACCAGTTGCGCAAGAGCGGTGTTGCCGCCGTGTTCGGAGATGCCGCCCACCCC
GCGGTGTTGATCCAGGCGCACATTGCACATGCGGCGATGCTGGTCGTTGCCACGCCGAAGACGATCGACGTGCGCAAGAT
GGCAGAGACCGCCCGGACCCTGAACCCCGGCATCGAGATCATCCTGCGCACGCACAGCGAAGACGACGCCGAACTGCTGG
CGCGGGAGAACATCGGCCGCGTCTTTTTTGGGGAGGAGGAACTCGCCAAAGGCATGGCCGGCCACGTGGTGGCACGGTTT
GCGCCTGCGCCGGCCACGCATCGGCCGGCGCAGCACGCCTGA

Upstream 100 bases:

>100_bases
GGCACCTGCCCTTTCTTTTTCTGCTAGCCGCTTCGTTCGTTGCGCCACGCCGGGCTCCCTGGCGTGCCGGTGACGGGGCG
CTTCACCGGTGCCGTTGCCC

Downstream 100 bases:

>100_bases
GGGGCGTTACGGCGCTTCGGGCGTGTCCGTTGCCGGTTGCGGCGGCGCGCCCGCTTCGGGATTCGAAATCCGGGTGGCGA
GGATCTTGTCGATGCGCTTG

Product: putative potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MPHDVSLIATLAVGFGLALLLGFIADRLRLPALVGYLLAGILIGPATPGFVADVGIAGQLAEIGVMLLMFGVGLHFSLED
LLAVRRIALPGAVVQMAVATLLGMGMAALWGWNLGAGLIFGLSLSVASTVVLLKALETRGILETVNGRIAVGWLVVEDLA
MVVVLVLLPPLAGLLGGTAEVEPSQPLWRTVGLTLLQVGAFVALMLLVGRRVLPWLLWQVAGSGSRELFTLGVIAAAVSI
AFGAAQLFGVSFALGAFFAGMVMRESEFSHRAAQESLPLRDAFAVLFFVSVGMLFDPSVLVEYPLHVLGVVAVIIVGKSI
AAAALVIAFRYPLNTALTVAASLAQIGEFSFILAGLGMALGLLPAAGQSLILAGALISIAANPFVFATVRPAGKWMLDNW
SVARRLALRADPLTELPMSTERDFLEGQVVLVGYGRVGRRIAEALQARDIPYVVAEQNRERVDQLRKSGVAAVFGDAAHP
AVLIQAHIAHAAMLVVATPKTIDVRKMAETARTLNPGIEIILRTHSEDDAELLARENIGRVFFGEEELAKGMAGHVVARF
APAPATHRPAQHA

Sequences:

>Translated_573_residues
MPHDVSLIATLAVGFGLALLLGFIADRLRLPALVGYLLAGILIGPATPGFVADVGIAGQLAEIGVMLLMFGVGLHFSLED
LLAVRRIALPGAVVQMAVATLLGMGMAALWGWNLGAGLIFGLSLSVASTVVLLKALETRGILETVNGRIAVGWLVVEDLA
MVVVLVLLPPLAGLLGGTAEVEPSQPLWRTVGLTLLQVGAFVALMLLVGRRVLPWLLWQVAGSGSRELFTLGVIAAAVSI
AFGAAQLFGVSFALGAFFAGMVMRESEFSHRAAQESLPLRDAFAVLFFVSVGMLFDPSVLVEYPLHVLGVVAVIIVGKSI
AAAALVIAFRYPLNTALTVAASLAQIGEFSFILAGLGMALGLLPAAGQSLILAGALISIAANPFVFATVRPAGKWMLDNW
SVARRLALRADPLTELPMSTERDFLEGQVVLVGYGRVGRRIAEALQARDIPYVVAEQNRERVDQLRKSGVAAVFGDAAHP
AVLIQAHIAHAAMLVVATPKTIDVRKMAETARTLNPGIEIILRTHSEDDAELLARENIGRVFFGEEELAKGMAGHVVARF
APAPATHRPAQHA
>Mature_572_residues
PHDVSLIATLAVGFGLALLLGFIADRLRLPALVGYLLAGILIGPATPGFVADVGIAGQLAEIGVMLLMFGVGLHFSLEDL
LAVRRIALPGAVVQMAVATLLGMGMAALWGWNLGAGLIFGLSLSVASTVVLLKALETRGILETVNGRIAVGWLVVEDLAM
VVVLVLLPPLAGLLGGTAEVEPSQPLWRTVGLTLLQVGAFVALMLLVGRRVLPWLLWQVAGSGSRELFTLGVIAAAVSIA
FGAAQLFGVSFALGAFFAGMVMRESEFSHRAAQESLPLRDAFAVLFFVSVGMLFDPSVLVEYPLHVLGVVAVIIVGKSIA
AAALVIAFRYPLNTALTVAASLAQIGEFSFILAGLGMALGLLPAAGQSLILAGALISIAANPFVFATVRPAGKWMLDNWS
VARRLALRADPLTELPMSTERDFLEGQVVLVGYGRVGRRIAEALQARDIPYVVAEQNRERVDQLRKSGVAAVFGDAAHPA
VLIQAHIAHAAMLVVATPKTIDVRKMAETARTLNPGIEIILRTHSEDDAELLARENIGRVFFGEEELAKGMAGHVVARFA
PAPATHRPAQHA

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=368, Percent_Identity=28.5326086956522, Blast_Score=106, Evalue=7e-23,
Organism=Escherichia coli, GI1786685, Length=553, Percent_Identity=53.1645569620253, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1789749, Length=513, Percent_Identity=29.6296296296296, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786232, Length=528, Percent_Identity=29.5454545454545, Blast_Score=158, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 60354; Mature: 60223

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEECHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHDVSLIATLAVGFGLALLLGFIADRLRLPALVGYLLAGILIGPATPGFVADVGIAGQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHH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EEECHHHHHCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]