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The map label for this gene is FtsW [H]

Identifier: 119897174

GI number: 119897174

Start: 944801

End: 946033

Strand: Direct

Name: FtsW [H]

Synonym: azo0883

Alternate gene names: 119897174

Gene position: 944801-946033 (Clockwise)

Preceding gene: 119897173

Following gene: 119897175

Centisome position: 21.59

GC content: 66.67

Gene sequence:

>1233_bases
ATGAAGCTCGGCGCCCTGTTCTCGGCCTGGTTCCCGTCGCGGCCGGCGCCTGTCGGCGGCGGCGAGACGGCGCGCGTGGT
CAGCCGCCTTGCGCGGCCGGGCGCACCTGCGCGCGAACTCGATCTGCTGCTGATCTGGTCGGCGGTCGGCCTGCTGCTGC
TCGGCCTGGTCATGGTGTATTCGGCCTCGATCGCGATCGCCGAGGGCAGTCGGTTCACCAACAACCAGTCGCACTACTTC
CTGTTGCGCCACGCAATCTTCCTCGCCATCGGGATCGGCTGCGGGCTGGCCGCGTTCCAGCTGCCGATGGCGAAGTGGCA
GCGGCTTGCGCCAGCCCTGTTCGTGGGCGGGGTGGTGCTGCTGATCGTGGTGCTGATCCCTGGCATCGGCCGCGAGGTCA
ATGGCGCCCAGCGCTGGCTGTCGCTCGGTCCGGTCAACCTGCAGCCGTCCGAACTGATGAAGGTCTTCGTCGCCCTCTAC
GCGGCCGACTATACGGTACGCAAGCTCGACGCCATGGGCAGCTTCACCCGCGGCTTCCTGCCGATGATGACGGTGATCCT
GTTCGTCGGCTTCCTGCTGCTGCGCGAGCCCGACTTCGGCGCCTTCGTCGTGATCACCACCATCGCCTTCGGCGTGCTCT
TCCTGGGCGGCGTGAATGTGCGCGTGTTTGCGCTGCTGGCGGTGGTCGCGGTGATCGGCTTCATCATCCTGATCTGGACC
TCGCCCTACCGGCGCGAGCGCATCTTCGGCTTCATGGACCCGTGGCAGGACGCCTTCGGCAAGGGCTACCAGCTGTCGCA
CGCGCTGATCGCTTTCGGCCGCGGCGAATGGTTCGGCGTCGGCCTCGGCGGCAGCGTCGAAAAGCTGTTCTACCTGCCGG
AAGCCCACACCGACTTCCTGCTCGCGGTGATCGCCGAGGAACTCGGCTTTGCCGGCGTGGTGATGGTGGTGGCGCTGTTC
GCCATCCTCGTGCAGCGCACCTTCGCGATCGGCCGGGAGGCGATCAAGCTCGAACGCTACTTCTCCGGCCTGGTCGCGCT
GGGCATGGGTTTGTGGATGGGGGTGCAGTCCTTCATCAACATGGGCGTGAACATGGGCCTGCTGCCGACCAAGGGCCTGA
CCTTGCCGATGATGAGCTTCGGCGGTTCGGGCATCGTCGCCAACTGCGTGGCGCTGGCGATCCTGCTGCGGATCGACTGG
GAAGTCCGTCAGTTGAAGCGGGGTGGCGCATGA

Upstream 100 bases:

>100_bases
TGTCCCCCGCGTGCGCCAGCCTCGACATGTTCCGCAACTACGCCCACCGCGCCGAAGTGTTCATCGCCGCGGTGCGCCGC
CTGCCCGAGGTCAGCCCGCG

Downstream 100 bases:

>100_bases
AGACCCTGCTGGTGATGGCGGGCGGTACCGGCGGCCACATCTTCCCCGGCATCGCGGTGGCGGAAGCGCTGCGTGCGAAG
GGCTGGCGCATCGTCTGGAT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKLGALFSAWFPSRPAPVGGGETARVVSRLARPGAPARELDLLLIWSAVGLLLLGLVMVYSASIAIAEGSRFTNNQSHYF
LLRHAIFLAIGIGCGLAAFQLPMAKWQRLAPALFVGGVVLLIVVLIPGIGREVNGAQRWLSLGPVNLQPSELMKVFVALY
AADYTVRKLDAMGSFTRGFLPMMTVILFVGFLLLREPDFGAFVVITTIAFGVLFLGGVNVRVFALLAVVAVIGFIILIWT
SPYRRERIFGFMDPWQDAFGKGYQLSHALIAFGRGEWFGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFAGVVMVVALF
AILVQRTFAIGREAIKLERYFSGLVALGMGLWMGVQSFINMGVNMGLLPTKGLTLPMMSFGGSGIVANCVALAILLRIDW
EVRQLKRGGA

Sequences:

>Translated_410_residues
MKLGALFSAWFPSRPAPVGGGETARVVSRLARPGAPARELDLLLIWSAVGLLLLGLVMVYSASIAIAEGSRFTNNQSHYF
LLRHAIFLAIGIGCGLAAFQLPMAKWQRLAPALFVGGVVLLIVVLIPGIGREVNGAQRWLSLGPVNLQPSELMKVFVALY
AADYTVRKLDAMGSFTRGFLPMMTVILFVGFLLLREPDFGAFVVITTIAFGVLFLGGVNVRVFALLAVVAVIGFIILIWT
SPYRRERIFGFMDPWQDAFGKGYQLSHALIAFGRGEWFGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFAGVVMVVALF
AILVQRTFAIGREAIKLERYFSGLVALGMGLWMGVQSFINMGVNMGLLPTKGLTLPMMSFGGSGIVANCVALAILLRIDW
EVRQLKRGGA
>Mature_410_residues
MKLGALFSAWFPSRPAPVGGGETARVVSRLARPGAPARELDLLLIWSAVGLLLLGLVMVYSASIAIAEGSRFTNNQSHYF
LLRHAIFLAIGIGCGLAAFQLPMAKWQRLAPALFVGGVVLLIVVLIPGIGREVNGAQRWLSLGPVNLQPSELMKVFVALY
AADYTVRKLDAMGSFTRGFLPMMTVILFVGFLLLREPDFGAFVVITTIAFGVLFLGGVNVRVFALLAVVAVIGFIILIWT
SPYRRERIFGFMDPWQDAFGKGYQLSHALIAFGRGEWFGVGLGGSVEKLFYLPEAHTDFLLAVIAEELGFAGVVMVVALF
AILVQRTFAIGREAIKLERYFSGLVALGMGLWMGVQSFINMGVNMGLLPTKGLTLPMMSFGGSGIVANCVALAILLRIDW
EVRQLKRGGA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=366, Percent_Identity=42.896174863388, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1786853, Length=325, Percent_Identity=33.2307692307692, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44390; Mature: 44390

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]