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The map label for this gene is murG

Identifier: 119897175

GI number: 119897175

Start: 946030

End: 947100

Strand: Direct

Name: murG

Synonym: azo0884

Alternate gene names: 119897175

Gene position: 946030-947100 (Clockwise)

Preceding gene: 119897174

Following gene: 119897176

Centisome position: 21.62

GC content: 71.34

Gene sequence:

>1071_bases
ATGAAGACCCTGCTGGTGATGGCGGGCGGTACCGGCGGCCACATCTTCCCCGGCATCGCGGTGGCGGAAGCGCTGCGTGC
GAAGGGCTGGCGCATCGTCTGGATGGGTAATCCGGACGGCATGGAGGCGCGCATCGTCCCGAGCCGCGGCTACGACACCG
CCTGGGTGCGCTTCGGCGCGCTGCGGGGCAAGGGGCTGGTGCGCAAGCTGCTGCTGCCGGTCAACTTGCTGGTCGGCTTC
TGGCAGGCGCTCGGTCAGCTGCGCCGCATCAAGCCCGATGTCGTGCTCGGCATGGGCGGCTACATCACCTTCCCCGGCGG
CATGATGGCGGCGCTCCTCGGCTGGCCGTTGGTGCTGCACGAACAGAATTCGGTTGCCGGGCTCGCCAACCGCGTGCTCG
CCGGCGTCGCCGACCGCGTGCTGTCGGGCTTTCCGTCGGTGCTGAAGAAGGCGGGCTGGGTGGGCAACCCGGTGCGCGAG
GACATCGCCTCCGTGGCGGCGCCGGCCGCGCGCTTCGCCGGCCGCAGCGGCCCGCTCAATGTGCTGGTGGTGGGCGGCAG
CCTCGGCGCCGCGGTGCTCAACGACACCGTGCCCAAGGCGCTCGCGCGCATTCCGCTGGAGTTCCGCCCGCAGGTGGTGC
ACCAGGCTGGTGAAAAGCAGATCGATGCGCTGCGTGCGGCCTATGCGGCGGCCGGCGTGGAAGGCGACCTGCGCCCCTTC
ATCCAGGACATGGCCGCCGCTTACGCCGGGGCCGATCTGGTGATCTGCCGCGCCGGCGCGCTCACCGTGGCCGAACTTGC
GGCGGTCGGCGTGGCCAGCCTGCTGGTGCCCTTCCCGCACGCGGTGGACGACCACCAGACGGGCAACGCGCGTTTCCTGG
CCGAACACGGCGGCGCCTACCTGCTGCCGCAAAACGAACTCGACGCCGAACGACTGGCCGGCATTCTCGCCAGTCTGGAC
CGTCCGCAACTGTTGCAGATGGCCGAGCACGCCCGCGCGCAGGCGAAGCCGCGCGCGACCGAGGCGGTCGCCCGTGCCTG
CGAGGAACTGGCGGAGGGACGCAAGGCATGA

Upstream 100 bases:

>100_bases
TGATGAGCTTCGGCGGTTCGGGCATCGTCGCCAACTGCGTGGCGCTGGCGATCCTGCTGCGGATCGACTGGGAAGTCCGT
CAGTTGAAGCGGGGTGGCGC

Downstream 100 bases:

>100_bases
AACATAAAGTCAAACGCATCCACTTTGTAGGTATCGGCGGCGCCGGCATGAGCGGCATCGCCGAGGTGCTGGTCAACCTC
GGCTACAGCGTCAGCGGCTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKTLLVMAGGTGGHIFPGIAVAEALRAKGWRIVWMGNPDGMEARIVPSRGYDTAWVRFGALRGKGLVRKLLLPVNLLVGF
WQALGQLRRIKPDVVLGMGGYITFPGGMMAALLGWPLVLHEQNSVAGLANRVLAGVADRVLSGFPSVLKKAGWVGNPVRE
DIASVAAPAARFAGRSGPLNVLVVGGSLGAAVLNDTVPKALARIPLEFRPQVVHQAGEKQIDALRAAYAAAGVEGDLRPF
IQDMAAAYAGADLVICRAGALTVAELAAVGVASLLVPFPHAVDDHQTGNARFLAEHGGAYLLPQNELDAERLAGILASLD
RPQLLQMAEHARAQAKPRATEAVARACEELAEGRKA

Sequences:

>Translated_356_residues
MKTLLVMAGGTGGHIFPGIAVAEALRAKGWRIVWMGNPDGMEARIVPSRGYDTAWVRFGALRGKGLVRKLLLPVNLLVGF
WQALGQLRRIKPDVVLGMGGYITFPGGMMAALLGWPLVLHEQNSVAGLANRVLAGVADRVLSGFPSVLKKAGWVGNPVRE
DIASVAAPAARFAGRSGPLNVLVVGGSLGAAVLNDTVPKALARIPLEFRPQVVHQAGEKQIDALRAAYAAAGVEGDLRPF
IQDMAAAYAGADLVICRAGALTVAELAAVGVASLLVPFPHAVDDHQTGNARFLAEHGGAYLLPQNELDAERLAGILASLD
RPQLLQMAEHARAQAKPRATEAVARACEELAEGRKA
>Mature_356_residues
MKTLLVMAGGTGGHIFPGIAVAEALRAKGWRIVWMGNPDGMEARIVPSRGYDTAWVRFGALRGKGLVRKLLLPVNLLVGF
WQALGQLRRIKPDVVLGMGGYITFPGGMMAALLGWPLVLHEQNSVAGLANRVLAGVADRVLSGFPSVLKKAGWVGNPVRE
DIASVAAPAARFAGRSGPLNVLVVGGSLGAAVLNDTVPKALARIPLEFRPQVVHQAGEKQIDALRAAYAAAGVEGDLRPF
IQDMAAAYAGADLVICRAGALTVAELAAVGVASLLVPFPHAVDDHQTGNARFLAEHGGAYLLPQNELDAERLAGILASLD
RPQLLQMAEHARAQAKPRATEAVARACEELAEGRKA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=351, Percent_Identity=47.5783475783476, Blast_Score=301, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_AZOSB (A1K3U6)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932388.1
- ProteinModelPortal:   A1K3U6
- SMR:   A1K3U6
- STRING:   A1K3U6
- GeneID:   4608840
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0884
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A1K3U6
- ProtClustDB:   PRK00726
- BioCyc:   ASP62928:AZO0884-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37400; Mature: 37400

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLVMAGGTGGHIFPGIAVAEALRAKGWRIVWMGNPDGMEARIVPSRGYDTAWVRFGA
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHH
LRGKGLVRKLLLPVNLLVGFWQALGQLRRIKPDVVLGMGGYITFPGGMMAALLGWPLVLH
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCHHHHHHHHCCCEEEE
EQNSVAGLANRVLAGVADRVLSGFPSVLKKAGWVGNPVREDIASVAAPAARFAGRSGPLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VLVVGGSLGAAVLNDTVPKALARIPLEFRPQVVHQAGEKQIDALRAAYAAAGVEGDLRPF
EEEECCCCCHHHHHHHHHHHHHHCCHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHH
IQDMAAAYAGADLVICRAGALTVAELAAVGVASLLVPFPHAVDDHQTGNARFLAEHGGAY
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEE
LLPQNELDAERLAGILASLDRPQLLQMAEHARAQAKPRATEAVARACEELAEGRKA
ECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTLLVMAGGTGGHIFPGIAVAEALRAKGWRIVWMGNPDGMEARIVPSRGYDTAWVRFGA
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHH
LRGKGLVRKLLLPVNLLVGFWQALGQLRRIKPDVVLGMGGYITFPGGMMAALLGWPLVLH
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCHHHHHHHHCCCEEEE
EQNSVAGLANRVLAGVADRVLSGFPSVLKKAGWVGNPVREDIASVAAPAARFAGRSGPLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VLVVGGSLGAAVLNDTVPKALARIPLEFRPQVVHQAGEKQIDALRAAYAAAGVEGDLRPF
EEEECCCCCHHHHHHHHHHHHHHCCHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHH
IQDMAAAYAGADLVICRAGALTVAELAAVGVASLLVPFPHAVDDHQTGNARFLAEHGGAY
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEE
LLPQNELDAERLAGILASLDRPQLLQMAEHARAQAKPRATEAVARACEELAEGRKA
ECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA