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The map label for this gene is macB [H]

Identifier: 119897123

GI number: 119897123

Start: 890060

End: 891259

Strand: Reverse

Name: macB [H]

Synonym: azo0832

Alternate gene names: 119897123

Gene position: 891259-890060 (Counterclockwise)

Preceding gene: 119897124

Following gene: 119897122

Centisome position: 20.37

GC content: 71.67

Gene sequence:

>1200_bases
ATGCTGTGGCGCGACTTCCTGCAACTGGCCCTGCGCTCGCTCACCGCGCACCGCCTGCGCAGCTTCCTGACCCTGCTCGG
CATCGGCGTCGGCATCGCCGCGGTGATCCTGCTGACTTCGATCGGCGAAGGGCTGCATCGCTTCGTGCTGCAGGAATTCA
CCCAGTTCGGCACCAACATCATCAAGGTCACGCCCGGCAAGACCGGCGCCCGCGGCGGCCCGCCCGGCCTGCCCTCCACC
ACGCGCGAGCTCACGCTCGACGACGCCGCGGCGCTGGCGCGCGCCCCCTACGTCACCGGCATCACGCCCACGGTGTCGGG
CAATTCCGAAGTGCGCGCCAACGGCCGCGTGCGGCGCACCTTCATCATGGGCGCCGGGGCGCAGATGCAGCAGGTGTTCT
CGATGCGGGTCAAGAGCGGGCGCTTCCTGCCGCCGGACGATGCCGCCCACGCCCGCGCCTTCGTCGTGCTGGGCGCGACG
CTCAAGCGCGAACTCTTCGGCAACGCCAACGCGCTTGGCGAGCGGCTGCAGATCGGCGGCGAACGCTACCGGGTGATCGG
CGTGATGGAGAGCAAGGGCCAGTTCCTCGGCATCGACCTGGACGACGCGGCCTACATTCCCGCGGCGCGCGCGCTGGCGC
TGTACAACCGCGACGGCCTGATGGAAATCAACGTCACCTACAACGAAGGCGTGTCGGCCGCGCGCGCCGCGGCCGAGGTG
CGCAAGGTGATGCGCGCCCGCCACGGGCGCGAGGACTTCACCCTGACCACGCAGGAAGACATGCTGGCGACGCTGTCGAA
CATCCTCGGCATCCTCACCGCGGCGGTCGGCGCGCTCGGCGGCATCTCGCTGCTGGTGGGCGGCGTCGGCATCGTCACGA
TCATGACCATCGCGGTGGCCGAGCGCACCGCGGAGATCGGCCTGCTGGTGGCGCTCGGCGCCCGTCGCACCACCATCCTC
GGCCTCTTCCTCGGCGAAGCGGTGGCGCTGGCGGCGATCGGCGGTGCGGTGGGGCTCGCGGTTGGCGCCGGCCTTGCGCA
ACTGGTCGGCCTGGCCGTGCCGGCGCTGCCGGTGTCGACCCCGTGGCGTTTCGTTGCGATCGCCGAAGCGCTCGCGGTGC
TGATCGGCCTCACCGCCGGCGTGCTGCCGGCACGCCGTGCGGCCCGTCTGGACCCGGTGGAGGCGCTGCGCGCGCAATGA

Upstream 100 bases:

>100_bases
CACCGCGCTCGGCACCGGCCTGCTGTTCGGCGTACTGCCGGCGCGCCGCGCCGCCCGGCTCGATCCGGTGCAGGCGCTGG
CCAAGCGCTAGGCGACGATC

Downstream 100 bases:

>100_bases
AACCGTTCGTGCACCATCCGTCCCTCGCCCCATCGCTGCTGCGCGGCCCCGCACGCAGGCTCGCCGCCGTATTGCTGCTC
GCTCCCGCCGTGGCCCTGGC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLWRDFLQLALRSLTAHRLRSFLTLLGIGVGIAAVILLTSIGEGLHRFVLQEFTQFGTNIIKVTPGKTGARGGPPGLPST
TRELTLDDAAALARAPYVTGITPTVSGNSEVRANGRVRRTFIMGAGAQMQQVFSMRVKSGRFLPPDDAAHARAFVVLGAT
LKRELFGNANALGERLQIGGERYRVIGVMESKGQFLGIDLDDAAYIPAARALALYNRDGLMEINVTYNEGVSAARAAAEV
RKVMRARHGREDFTLTTQEDMLATLSNILGILTAAVGALGGISLLVGGVGIVTIMTIAVAERTAEIGLLVALGARRTTIL
GLFLGEAVALAAIGGAVGLAVGAGLAQLVGLAVPALPVSTPWRFVAIAEALAVLIGLTAGVLPARRAARLDPVEALRAQ

Sequences:

>Translated_399_residues
MLWRDFLQLALRSLTAHRLRSFLTLLGIGVGIAAVILLTSIGEGLHRFVLQEFTQFGTNIIKVTPGKTGARGGPPGLPST
TRELTLDDAAALARAPYVTGITPTVSGNSEVRANGRVRRTFIMGAGAQMQQVFSMRVKSGRFLPPDDAAHARAFVVLGAT
LKRELFGNANALGERLQIGGERYRVIGVMESKGQFLGIDLDDAAYIPAARALALYNRDGLMEINVTYNEGVSAARAAAEV
RKVMRARHGREDFTLTTQEDMLATLSNILGILTAAVGALGGISLLVGGVGIVTIMTIAVAERTAEIGLLVALGARRTTIL
GLFLGEAVALAAIGGAVGLAVGAGLAQLVGLAVPALPVSTPWRFVAIAEALAVLIGLTAGVLPARRAARLDPVEALRAQ
>Mature_399_residues
MLWRDFLQLALRSLTAHRLRSFLTLLGIGVGIAAVILLTSIGEGLHRFVLQEFTQFGTNIIKVTPGKTGARGGPPGLPST
TRELTLDDAAALARAPYVTGITPTVSGNSEVRANGRVRRTFIMGAGAQMQQVFSMRVKSGRFLPPDDAAHARAFVVLGAT
LKRELFGNANALGERLQIGGERYRVIGVMESKGQFLGIDLDDAAYIPAARALALYNRDGLMEINVTYNEGVSAARAAAEV
RKVMRARHGREDFTLTTQEDMLATLSNILGILTAAVGALGGISLLVGGVGIVTIMTIAVAERTAEIGLLVALGARRTTIL
GLFLGEAVALAAIGGAVGLAVGAGLAQLVGLAVPALPVSTPWRFVAIAEALAVLIGLTAGVLPARRAARLDPVEALRAQ

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=32.258064516129, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41755; Mature: 41755

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWRDFLQLALRSLTAHRLRSFLTLLGIGVGIAAVILLTSIGEGLHRFVLQEFTQFGTNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IKVTPGKTGARGGPPGLPSTTRELTLDDAAALARAPYVTGITPTVSGNSEVRANGRVRRT
EEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCEEEE
FIMGAGAQMQQVFSMRVKSGRFLPPDDAAHARAFVVLGATLKRELFGNANALGERLQIGG
EEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEHHHHHHHHCCCHHHHHHHHHCCC
ERYRVIGVMESKGQFLGIDLDDAAYIPAARALALYNRDGLMEINVTYNEGVSAARAAAEV
CEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHH
RKVMRARHGREDFTLTTQEDMLATLSNILGILTAAVGALGGISLLVGGVGIVTIMTIAVA
HHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTAEIGLLVALGARRTTILGLFLGEAVALAAIGGAVGLAVGAGLAQLVGLAVPALPVST
HHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PWRFVAIAEALAVLIGLTAGVLPARRAARLDPVEALRAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MLWRDFLQLALRSLTAHRLRSFLTLLGIGVGIAAVILLTSIGEGLHRFVLQEFTQFGTNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IKVTPGKTGARGGPPGLPSTTRELTLDDAAALARAPYVTGITPTVSGNSEVRANGRVRRT
EEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCEEEE
FIMGAGAQMQQVFSMRVKSGRFLPPDDAAHARAFVVLGATLKRELFGNANALGERLQIGG
EEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEHHHHHHHHCCCHHHHHHHHHCCC
ERYRVIGVMESKGQFLGIDLDDAAYIPAARALALYNRDGLMEINVTYNEGVSAARAAAEV
CEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHH
RKVMRARHGREDFTLTTQEDMLATLSNILGILTAAVGALGGISLLVGGVGIVTIMTIAVA
HHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTAEIGLLVALGARRTTILGLFLGEAVALAAIGGAVGLAVGAGLAQLVGLAVPALPVST
HHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PWRFVAIAEALAVLIGLTAGVLPARRAARLDPVEALRAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA