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The map label for this gene is macB [H]

Identifier: 119897124

GI number: 119897124

Start: 891269

End: 892477

Strand: Reverse

Name: macB [H]

Synonym: azo0833

Alternate gene names: 119897124

Gene position: 892477-891269 (Counterclockwise)

Preceding gene: 119897125

Following gene: 119897123

Centisome position: 20.39

GC content: 72.29

Gene sequence:

>1209_bases
ATGAGCCCGCGCGACACGCTGCGCTTTGCCGCCGGCGCCGCGTTCGGCTATCCGCTGCGCACCGCGCTGATGGTGCTGGC
GATGGCGATCGGCGTGGCGGCGGTGGTGGTGCTCACCGCACTCGGCGACGGCGCGCGCCGCTACGTCGTCGGCGAGTTCG
CCTCGCTCGGCGCCAACCTCATCATCGTGCTGCCGGGGCGCAATGAAACCGGCGGCGTCAACGCCGGCAGCTTCGTCACC
AGCACGCCGCGCGACCTCACCGTGGCCGACGCCAGCGCGCTGCTGCGCGCCCCGCTCGCGGCACGGATGGCGCCGCTGTC
GGTCGGCAATTCCGAGATCGCGGTCGGCGGCAAGCTGCGCGAGGTGATGGTGCTGGGCACCAGCGCCGACTACCTCGACA
TCCGCCACTACAGCCTGTCGCAAGGCCGCTTCCTGCCGCGGGAAGACCTCAACCGTGCGGGCGCGGTGGCGGTGATCGGC
GACAAGCTGCGCGAGGAGCTGTTCGGCAACGAACCCGCGGTGGGCCGCATGGTGCGGGTGGGCGACACCCGGCTGCGCAT
CATCGGCGTAATGGCACGCGGCGCGCAGGGGCTGGGGCTGAACACCGACGAGCTGGTGATAGTGCCGGTGGCCACCGCCC
TGGCGATGTTCAATACCAACACGCTGTTCCGCATCATGGTGGAGGCGCGCAGCCGCGAGGCCCTGGGGCCGGCGCAAAAA
CAGATGGAAGACATCCTGCGCGCGCGCCACGACGGCGAACTCGACGTCACGCTGATCACGCAGGACGCGGTGCTCGGCAC
CTTCGACCGCATCCTCGGCGCGCTGACCATGGCCGTGGCTGGCATCGCCGCAATCAGCCTCGCGGTGGCCGGCATCCTGG
TGATGAACGTGATGCTCGTGGCCGTCACCCAGCGCACCGGGGAAATCGGCCTGCTGAAGGCGCTGGGCGCGAGCGCGCGC
ACGATCCGCCTGGCCTTCCTTACCGAGGCCGCGCTGCTGTCGCTGGCCGGCGCGCTGGTGGGCTACGGGCTCGGCCAGCT
CGGCGCCTGGGCCATCCGCCTGACCTGGCCGGTGCTGCCGGCCTGGCCGCCGGACTGGGCGGTGGTGGCCGGACTGGGCA
CCGCGCTCGGCACCGGCCTGCTGTTCGGCGTACTGCCGGCGCGCCGCGCCGCCCGGCTCGATCCGGTGCAGGCGCTGGCC
AAGCGCTAG

Upstream 100 bases:

>100_bases
ACCCGGCGATGGGCAACCGCGCCCGCCGCCGCCTGATGATGGAGGACGGCATGCTGCGCCAGGACCTGCGCGACGGCACG
CCGGCGCCCACGGGCACGCC

Downstream 100 bases:

>100_bases
GCGACGATCATGCTGTGGCGCGACTTCCTGCAACTGGCCCTGCGCTCGCTCACCGCGCACCGCCTGCGCAGCTTCCTGAC
CCTGCTCGGCATCGGCGTCG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSPRDTLRFAAGAAFGYPLRTALMVLAMAIGVAAVVVLTALGDGARRYVVGEFASLGANLIIVLPGRNETGGVNAGSFVT
STPRDLTVADASALLRAPLAARMAPLSVGNSEIAVGGKLREVMVLGTSADYLDIRHYSLSQGRFLPREDLNRAGAVAVIG
DKLREELFGNEPAVGRMVRVGDTRLRIIGVMARGAQGLGLNTDELVIVPVATALAMFNTNTLFRIMVEARSREALGPAQK
QMEDILRARHDGELDVTLITQDAVLGTFDRILGALTMAVAGIAAISLAVAGILVMNVMLVAVTQRTGEIGLLKALGASAR
TIRLAFLTEAALLSLAGALVGYGLGQLGAWAIRLTWPVLPAWPPDWAVVAGLGTALGTGLLFGVLPARRAARLDPVQALA
KR

Sequences:

>Translated_402_residues
MSPRDTLRFAAGAAFGYPLRTALMVLAMAIGVAAVVVLTALGDGARRYVVGEFASLGANLIIVLPGRNETGGVNAGSFVT
STPRDLTVADASALLRAPLAARMAPLSVGNSEIAVGGKLREVMVLGTSADYLDIRHYSLSQGRFLPREDLNRAGAVAVIG
DKLREELFGNEPAVGRMVRVGDTRLRIIGVMARGAQGLGLNTDELVIVPVATALAMFNTNTLFRIMVEARSREALGPAQK
QMEDILRARHDGELDVTLITQDAVLGTFDRILGALTMAVAGIAAISLAVAGILVMNVMLVAVTQRTGEIGLLKALGASAR
TIRLAFLTEAALLSLAGALVGYGLGQLGAWAIRLTWPVLPAWPPDWAVVAGLGTALGTGLLFGVLPARRAARLDPVQALA
KR
>Mature_401_residues
SPRDTLRFAAGAAFGYPLRTALMVLAMAIGVAAVVVLTALGDGARRYVVGEFASLGANLIIVLPGRNETGGVNAGSFVTS
TPRDLTVADASALLRAPLAARMAPLSVGNSEIAVGGKLREVMVLGTSADYLDIRHYSLSQGRFLPREDLNRAGAVAVIGD
KLREELFGNEPAVGRMVRVGDTRLRIIGVMARGAQGLGLNTDELVIVPVATALAMFNTNTLFRIMVEARSREALGPAQKQ
MEDILRARHDGELDVTLITQDAVLGTFDRILGALTMAVAGIAAISLAVAGILVMNVMLVAVTQRTGEIGLLKALGASART
IRLAFLTEAALLSLAGALVGYGLGQLGAWAIRLTWPVLPAWPPDWAVVAGLGTALGTGLLFGVLPARRAARLDPVQALAK
R

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=396, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42027; Mature: 41896

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRDTLRFAAGAAFGYPLRTALMVLAMAIGVAAVVVLTALGDGARRYVVGEFASLGANL
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
IIVLPGRNETGGVNAGSFVTSTPRDLTVADASALLRAPLAARMAPLSVGNSEIAVGGKLR
EEEECCCCCCCCCCCCCEECCCCCCEEHHHHHHHHHCCHHHHHCCCCCCCCCEEECCCEE
EVMVLGTSADYLDIRHYSLSQGRFLPREDLNRAGAVAVIGDKLREELFGNEPAVGRMVRV
EEEEECCCCCEEEEEEEECCCCCCCCHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCEEEE
GDTRLRIIGVMARGAQGLGLNTDELVIVPVATALAMFNTNTLFRIMVEARSREALGPAQK
CCCEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHH
QMEDILRARHDGELDVTLITQDAVLGTFDRILGALTMAVAGIAAISLAVAGILVMNVMLV
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTQRTGEIGLLKALGASARTIRLAFLTEAALLSLAGALVGYGLGQLGAWAIRLTWPVLP
HHHHCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHCEEEEEEEECCCC
AWPPDWAVVAGLGTALGTGLLFGVLPARRAARLDPVQALAKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure 
SPRDTLRFAAGAAFGYPLRTALMVLAMAIGVAAVVVLTALGDGARRYVVGEFASLGANL
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
IIVLPGRNETGGVNAGSFVTSTPRDLTVADASALLRAPLAARMAPLSVGNSEIAVGGKLR
EEEECCCCCCCCCCCCCEECCCCCCEEHHHHHHHHHCCHHHHHCCCCCCCCCEEECCCEE
EVMVLGTSADYLDIRHYSLSQGRFLPREDLNRAGAVAVIGDKLREELFGNEPAVGRMVRV
EEEEECCCCCEEEEEEEECCCCCCCCHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCEEEE
GDTRLRIIGVMARGAQGLGLNTDELVIVPVATALAMFNTNTLFRIMVEARSREALGPAQK
CCCEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEEEEHHHCCCCCCHHHH
QMEDILRARHDGELDVTLITQDAVLGTFDRILGALTMAVAGIAAISLAVAGILVMNVMLV
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTQRTGEIGLLKALGASARTIRLAFLTEAALLSLAGALVGYGLGQLGAWAIRLTWPVLP
HHHHCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHCEEEEEEEECCCC
AWPPDWAVVAGLGTALGTGLLFGVLPARRAARLDPVQALAKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]