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The map label for this gene is lptA [H]

Identifier: 119897082

GI number: 119897082

Start: 849202

End: 849774

Strand: Reverse

Name: lptA [H]

Synonym: azo0791

Alternate gene names: 119897082

Gene position: 849774-849202 (Counterclockwise)

Preceding gene: 119897083

Following gene: 119897081

Centisome position: 19.42

GC content: 67.36

Gene sequence:

>573_bases
ATGAAGCTCCTCAACCGCGCCCTTCTGGCCCCGGCCGCCCTGACCCTTGCACTGGCCGCTGCGCCGGCCCTTGCCGAGCG
CGCCGACCGCGACCAGCCGGTCAACATCGAAGCCAACAAGGTCACGGTGGACGACCGCAACAAGGTCCACATCTTCGAAG
GCGACGTCGTCCTGACCCAGGGCACGCTGGTCATCAAGGGCGACAAGCTGGTGGTCACGCAGGACGCCGGCGGTTTCCAG
AATGGCGTTGCCACCGCCTCCAACCCGCGCCTGGCCACCTTCCGCCAGAAGCGCGAAGGCAGCAACGAATACGTTTACGG
CGAAGCCGAGCGGATCGAGTACAGCAGCCGCACCGAGAAAGCCAAGCTCTTCGTGCGCGCCAAGGTCACCAGCGGCGGCG
ACGAAGTGCGCGGCCACTTCATCGAGTACGACTCGATGAGCGAGAACTACCTCGTCACCAATGCTCCCGGCGCCGCGCCG
GCCGCCACCAGCGGCGGCGACGGCCGGGTGCGCGCGGTGATCCAGCCCAAGAGTGACAACAAAGCGGGCGGCGCCGAAAG
CGCCAAGCCCTGA

Upstream 100 bases:

>100_bases
CTGCGCAGGCCCAGGGCATGCACGCAGACAACCTGTTCGGCACGCTGGAACTGATCGGCCAAGCCCGCGTCCGCCTGCCC
CGTCGTCAAGAGAATCCGTC

Downstream 100 bases:

>100_bases
AAACCACGCACTGCCCAGGAGATAGCATGAGCTTCGAGAACATCCTCACCGAGACCCGCGGCCGCGTCGGGCTCATCACC
CTCAACCGGCCGAAGGCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKLLNRALLAPAALTLALAAAPALAERADRDQPVNIEANKVTVDDRNKVHIFEGDVVLTQGTLVIKGDKLVVTQDAGGFQ
NGVATASNPRLATFRQKREGSNEYVYGEAERIEYSSRTEKAKLFVRAKVTSGGDEVRGHFIEYDSMSENYLVTNAPGAAP
AATSGGDGRVRAVIQPKSDNKAGGAESAKP

Sequences:

>Translated_190_residues
MKLLNRALLAPAALTLALAAAPALAERADRDQPVNIEANKVTVDDRNKVHIFEGDVVLTQGTLVIKGDKLVVTQDAGGFQ
NGVATASNPRLATFRQKREGSNEYVYGEAERIEYSSRTEKAKLFVRAKVTSGGDEVRGHFIEYDSMSENYLVTNAPGAAP
AATSGGDGRVRAVIQPKSDNKAGGAESAKP
>Mature_190_residues
MKLLNRALLAPAALTLALAAAPALAERADRDQPVNIEANKVTVDDRNKVHIFEGDVVLTQGTLVIKGDKLVVTQDAGGFQ
NGVATASNPRLATFRQKREGSNEYVYGEAERIEYSSRTEKAKLFVRAKVTSGGDEVRGHFIEYDSMSENYLVTNAPGAAP
AATSGGDGRVRAVIQPKSDNKAGGAESAKP

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=113, Percent_Identity=38.0530973451327, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20198; Mature: 20198

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLNRALLAPAALTLALAAAPALAERADRDQPVNIEANKVTVDDRNKVHIFEGDVVLTQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECEEEECCCCEEEEEECCEEEEC
GTLVIKGDKLVVTQDAGGFQNGVATASNPRLATFRQKREGSNEYVYGEAERIEYSSRTEK
CEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEHHHHHCCCCCEEECCHHHEECCCCCCE
AKLFVRAKVTSGGDEVRGHFIEYDSMSENYLVTNAPGAAPAATSGGDGRVRAVIQPKSDN
EEEEEEEEECCCCCHHCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCC
KAGGAESAKP
CCCCCCCCCC
>Mature Secondary Structure
MKLLNRALLAPAALTLALAAAPALAERADRDQPVNIEANKVTVDDRNKVHIFEGDVVLTQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECEEEECCCCEEEEEECCEEEEC
GTLVIKGDKLVVTQDAGGFQNGVATASNPRLATFRQKREGSNEYVYGEAERIEYSSRTEK
CEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEHHHHHCCCCCEEECCHHHEECCCCCCE
AKLFVRAKVTSGGDEVRGHFIEYDSMSENYLVTNAPGAAPAATSGGDGRVRAVIQPKSDN
EEEEEEEEECCCCCHHCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCC
KAGGAESAKP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]