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The map label for this gene is pqqL [C]

Identifier: 119897056

GI number: 119897056

Start: 816645

End: 818111

Strand: Reverse

Name: pqqL [C]

Synonym: azo0765

Alternate gene names: 119897056

Gene position: 818111-816645 (Counterclockwise)

Preceding gene: 119897062

Following gene: 119897055

Centisome position: 18.7

GC content: 69.05

Gene sequence:

>1467_bases
ATGCGGCTCCCCGGCGGACGGGTGGGCTCCGCCCTCGAAAAGCGCCGCGAATTCTACCAGATGCAGGACATCCCCATGTT
TCGGCTGACCTTTCCGCGCACACTCCTTTTCGCCGCCGTCCTGCTGGGCGGCGCTGTCCAGGCCGCGTCCGCACCGGACG
CGAACACCTTCGAAACCACGCTTCCCAACGGGATGAAGGTCATCGTCAAGGAAGACCGTCGCGCCCCGTCCGCGGTCCAT
ATGGTGTGGTACCGCAGCGGCTCGATGGACGAGCCGGACGGCGTGTCCGGCGTCGCCCACGTGCTCGAACACATGATGTT
CAAGGGCACCAAGAAGGTCGGCCCGGGCGAGTTCAACAAGCGCGTGGCCGAACTCGGCGGCCGCGACAACGCCTTCACCA
GCAAGGACTACACCGCCTACTTCCAGCAGATTCCGCCTTCGCACCTGGATGCCGTGATGGCACTCGAAGCGGACCGCATG
CGCAACCTCGTCATCACCGACGCCGAGTTCGGGCGCGAGGTCGAGGTCGTGAAGGAAGAGCGCCGCCTGCGCACCGACGA
CCAGCCGCGCGCGCTGGTTCATGAGCAGCTGATGGCGACGGCCTTCCAGGCGCACCCCTACCGGCGGCCGATCATCGGCT
GGATGAGCGACCTCGACGGCATGACCGCGAGCGACGCGCGCGCCTGGTACAAGCGCTGGTACGCCCCCAACAATGCCTAC
CTCGTCGTCGTCGGCGATGTCTCGCACGAAGCGGTGTTCCGCCAGGCGCGCGAACACTACGGCGTGATCCCGGCACGGCA
ACTGCCCCCCCGCCGCGTGCCGGCCGAACCGGAGCAGCGCGGCACGCGCCATGCCACCGTCAAGGCCCCCGCGGAGCTGC
CCTACCTGGCACTTGCATGGCACGCGCCGGCACTGCGCAACCCCGCTGCCGACCGCGACGCCTATGCGCTGCAGGTGCTG
GCCGCGGTGCTGGATGGCTACGACGGCGCCCGCCTCACCCGCAGACTGGTGCGCGACAGCCGCGTTGCGGTATCGGCCGG
TGCCGGCTACGACGCCACTGGCCGCGGTCCGGCGCTGTTCTACCTGGACGGCGTGCCGGCGCCGGGCAAAACCATGGACG
ACCTGGAGGCGGCGCTGCGTGCGGAAATCCAGCGCATTCGCGACGAAGGAGTGGGCGAGGACGAGCTGGCCCGCGTGAAG
ACCCAGGCGGTTGCCGCACAGGTCTACAAGCGCGACTCGCTGGTGGGGCAGGCGATGGAAATCGGCTTCCTCGAAGCCTC
CAACCTGTCGTGGCGCGACGATGAACGGCTGCTGGACGGCCTGCGCAGCGTCACCGCGGAGGAAGTTCGCAGCGTTGCGC
AACGCTATTTCGGCGACGACACCCTGACCGCGGCCCGCCTGTTCCCGCTGCCGATGGACAACAACGCGCCCCGCCCTGCC
GCAGCCCCCGCCGCCCTCCGTCACTGA

Upstream 100 bases:

>100_bases
GCGTTCGTACACGGCAGCCCGGCTTGCAGCACGCTGCAACGCGGCCGCCACGACCGGATGCCAGGTGCCGGCGAGGCACG
GCGTTCCGGATAAGGCTAAG

Downstream 100 bases:

>100_bases
GCGTCCAGCCCCGACCGCGAGCCTGACCATGACAACGACACTTCCGCGTCCGCTCCCCCGTCCGTTTGCCTTCCTGCTCG
GCGTGCTCCTGCTCGCCGTA

Product: Zn dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRLPGGRVGSALEKRREFYQMQDIPMFRLTFPRTLLFAAVLLGGAVQAASAPDANTFETTLPNGMKVIVKEDRRAPSAVH
MVWYRSGSMDEPDGVSGVAHVLEHMMFKGTKKVGPGEFNKRVAELGGRDNAFTSKDYTAYFQQIPPSHLDAVMALEADRM
RNLVITDAEFGREVEVVKEERRLRTDDQPRALVHEQLMATAFQAHPYRRPIIGWMSDLDGMTASDARAWYKRWYAPNNAY
LVVVGDVSHEAVFRQAREHYGVIPARQLPPRRVPAEPEQRGTRHATVKAPAELPYLALAWHAPALRNPAADRDAYALQVL
AAVLDGYDGARLTRRLVRDSRVAVSAGAGYDATGRGPALFYLDGVPAPGKTMDDLEAALRAEIQRIRDEGVGEDELARVK
TQAVAAQVYKRDSLVGQAMEIGFLEASNLSWRDDERLLDGLRSVTAEEVRSVAQRYFGDDTLTAARLFPLPMDNNAPRPA
AAPAALRH

Sequences:

>Translated_488_residues
MRLPGGRVGSALEKRREFYQMQDIPMFRLTFPRTLLFAAVLLGGAVQAASAPDANTFETTLPNGMKVIVKEDRRAPSAVH
MVWYRSGSMDEPDGVSGVAHVLEHMMFKGTKKVGPGEFNKRVAELGGRDNAFTSKDYTAYFQQIPPSHLDAVMALEADRM
RNLVITDAEFGREVEVVKEERRLRTDDQPRALVHEQLMATAFQAHPYRRPIIGWMSDLDGMTASDARAWYKRWYAPNNAY
LVVVGDVSHEAVFRQAREHYGVIPARQLPPRRVPAEPEQRGTRHATVKAPAELPYLALAWHAPALRNPAADRDAYALQVL
AAVLDGYDGARLTRRLVRDSRVAVSAGAGYDATGRGPALFYLDGVPAPGKTMDDLEAALRAEIQRIRDEGVGEDELARVK
TQAVAAQVYKRDSLVGQAMEIGFLEASNLSWRDDERLLDGLRSVTAEEVRSVAQRYFGDDTLTAARLFPLPMDNNAPRPA
AAPAALRH
>Mature_488_residues
MRLPGGRVGSALEKRREFYQMQDIPMFRLTFPRTLLFAAVLLGGAVQAASAPDANTFETTLPNGMKVIVKEDRRAPSAVH
MVWYRSGSMDEPDGVSGVAHVLEHMMFKGTKKVGPGEFNKRVAELGGRDNAFTSKDYTAYFQQIPPSHLDAVMALEADRM
RNLVITDAEFGREVEVVKEERRLRTDDQPRALVHEQLMATAFQAHPYRRPIIGWMSDLDGMTASDARAWYKRWYAPNNAY
LVVVGDVSHEAVFRQAREHYGVIPARQLPPRRVPAEPEQRGTRHATVKAPAELPYLALAWHAPALRNPAADRDAYALQVL
AAVLDGYDGARLTRRLVRDSRVAVSAGAGYDATGRGPALFYLDGVPAPGKTMDDLEAALRAEIQRIRDEGVGEDELARVK
TQAVAAQVYKRDSLVGQAMEIGFLEASNLSWRDDERLLDGLRSVTAEEVRSVAQRYFGDDTLTAARLFPLPMDNNAPRPA
AAPAALRH

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=378, Percent_Identity=26.1904761904762, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI94538354, Length=341, Percent_Identity=27.8592375366569, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI155969707, Length=228, Percent_Identity=25, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787770, Length=392, Percent_Identity=27.8061224489796, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17553678, Length=289, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71999683, Length=344, Percent_Identity=26.1627906976744, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323192, Length=214, Percent_Identity=24.2990654205607, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323421, Length=195, Percent_Identity=24.1025641025641, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357875, Length=217, Percent_Identity=29.4930875576037, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646943, Length=217, Percent_Identity=29.4930875576037, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 54112; Mature: 54112

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPGGRVGSALEKRREFYQMQDIPMFRLTFPRTLLFAAVLLGGAVQAASAPDANTFETT
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
LPNGMKVIVKEDRRAPSAVHMVWYRSGSMDEPDGVSGVAHVLEHMMFKGTKKVGPGEFNK
CCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
RVAELGGRDNAFTSKDYTAYFQQIPPSHLDAVMALEADRMRNLVITDAEFGREVEVVKEE
HHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECHHHCCHHHHHHHH
RRLRTDDQPRALVHEQLMATAFQAHPYRRPIIGWMSDLDGMTASDARAWYKRWYAPNNAY
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCE
LVVVGDVSHEAVFRQAREHYGVIPARQLPPRRVPAEPEQRGTRHATVKAPAELPYLALAW
EEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCEEEEEE
HAPALRNPAADRDAYALQVLAAVLDGYDGARLTRRLVRDSRVAVSAGAGYDATGRGPALF
CCCHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEE
YLDGVPAPGKTMDDLEAALRAEIQRIRDEGVGEDELARVKTQAVAAQVYKRDSLVGQAME
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFLEASNLSWRDDERLLDGLRSVTAEEVRSVAQRYFGDDTLTAARLFPLPMDNNAPRPA
HCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECCCCCCCCCCCC
AAPAALRH
CCCHHHCC
>Mature Secondary Structure
MRLPGGRVGSALEKRREFYQMQDIPMFRLTFPRTLLFAAVLLGGAVQAASAPDANTFETT
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
LPNGMKVIVKEDRRAPSAVHMVWYRSGSMDEPDGVSGVAHVLEHMMFKGTKKVGPGEFNK
CCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
RVAELGGRDNAFTSKDYTAYFQQIPPSHLDAVMALEADRMRNLVITDAEFGREVEVVKEE
HHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECHHHCCHHHHHHHH
RRLRTDDQPRALVHEQLMATAFQAHPYRRPIIGWMSDLDGMTASDARAWYKRWYAPNNAY
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCE
LVVVGDVSHEAVFRQAREHYGVIPARQLPPRRVPAEPEQRGTRHATVKAPAELPYLALAW
EEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCEEEEEE
HAPALRNPAADRDAYALQVLAAVLDGYDGARLTRRLVRDSRVAVSAGAGYDATGRGPALF
CCCHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEE
YLDGVPAPGKTMDDLEAALRAEIQRIRDEGVGEDELARVKTQAVAAQVYKRDSLVGQAME
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFLEASNLSWRDDERLLDGLRSVTAEEVRSVAQRYFGDDTLTAARLFPLPMDNNAPRPA
HCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECCCCCCCCCCCC
AAPAALRH
CCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]