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The map label for this gene is lolB

Identifier: 119897048

GI number: 119897048

Start: 808543

End: 809124

Strand: Reverse

Name: lolB

Synonym: azo0757

Alternate gene names: 119897048

Gene position: 809124-808543 (Counterclockwise)

Preceding gene: 119897049

Following gene: 119897047

Centisome position: 18.49

GC content: 70.96

Gene sequence:

>582_bases
ATGAGGCCGGCTCGCCGATTCCTCGCGGCGCTGGCCTGCGTCGCGGGCGCGCTGCTGTCTGCCTGCGCCACGCCGACGCC
GCGCGCCGAACGCGCGGTACTCCGCGAAGTCAGCGCGCAGTTTTTCCTCGGCGGCCGGATGTCCGCCAGCGACGGCAATC
AGGGCGCCAGCGGACGGATCGAATGGCAGCACGATACCGCGGGCGACGAGGTGACCGTCTATTCGCCACTGGGGCAGATT
GCCGCGCGCCTGATCAGTTCGCCGACCGGCGCCGAGCTGCTGACCAGCGACGGCCAGCGCTACCAGGCGGAAAACGCCGA
GGCCCTGATGCCGCGCGTGTTCGGCTTTGGCGTGCCGGTTTCGCGCCTGGCGCACTGGGTGCAGGCCGCGCCGCCGCCGG
GCGCCGAAGTGCGCGAACTGGACGCAGCGGGCCGCCCGGCGCTGGTGATCGATCAGGGCTGGCGCGTCGATTATCTCGAG
TATCCGGATACGCGCGCCCGCACACTCCCCACCCGGGTAGAAGTCTCCCGCGGCGACGCACGCATCCGGCTGATCATCGA
CCAGTGGGAGCTGCTGCAATGA

Upstream 100 bases:

>100_bases
TGGACCGCCGCGAGGACGCCAACCGGCTGTTCGACGAAGCCTTGCGCGCCCATCCCGACAACACCGTGCTGCGCGACACC
GCCGCGCGCCTGCGCAAGCC

Downstream 100 bases:

>100_bases
CCATCAGCGGTGTCCTCGCCGGCTGCCCCGCGCCGGCCAAGCTGAACCTGTTCCTGCATGTCGTCGGACGCCGCGACGAC
GGCTACCACCTGCTGCAGAC

Product: outer membrane lipoprotein

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MRPARRFLAALACVAGALLSACATPTPRAERAVLREVSAQFFLGGRMSASDGNQGASGRIEWQHDTAGDEVTVYSPLGQI
AARLISSPTGAELLTSDGQRYQAENAEALMPRVFGFGVPVSRLAHWVQAAPPPGAEVRELDAAGRPALVIDQGWRVDYLE
YPDTRARTLPTRVEVSRGDARIRLIIDQWELLQ

Sequences:

>Translated_193_residues
MRPARRFLAALACVAGALLSACATPTPRAERAVLREVSAQFFLGGRMSASDGNQGASGRIEWQHDTAGDEVTVYSPLGQI
AARLISSPTGAELLTSDGQRYQAENAEALMPRVFGFGVPVSRLAHWVQAAPPPGAEVRELDAAGRPALVIDQGWRVDYLE
YPDTRARTLPTRVEVSRGDARIRLIIDQWELLQ
>Mature_193_residues
MRPARRFLAALACVAGALLSACATPTPRAERAVLREVSAQFFLGGRMSASDGNQGASGRIEWQHDTAGDEVTVYSPLGQI
AARLISSPTGAELLTSDGQRYQAENAEALMPRVFGFGVPVSRLAHWVQAAPPPGAEVRELDAAGRPALVIDQGWRVDYLE
YPDTRARTLPTRVEVSRGDARIRLIIDQWELLQ

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family

Homologues:

Organism=Escherichia coli, GI1787460, Length=199, Percent_Identity=25.1256281407035, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LOLB_AZOSB (A1K3G9)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932261.1
- ProteinModelPortal:   A1K3G9
- SMR:   A1K3G9
- STRING:   A1K3G9
- GeneID:   4609096
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0757
- eggNOG:   COG3017
- HOGENOM:   HBG336011
- OMA:   RIEASNG
- PhylomeDB:   A1K3G9
- ProtClustDB:   CLSK766418
- BioCyc:   ASP62928:AZO0757-MONOMER
- HAMAP:   MF_00233
- InterPro:   IPR004565
- TIGRFAMs:   TIGR00548

Pfam domain/function: PF03550 LolB

EC number: NA

Molecular weight: Translated: 20950; Mature: 20950

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPARRFLAALACVAGALLSACATPTPRAERAVLREVSAQFFLGGRMSASDGNQGASGRI
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
EWQHDTAGDEVTVYSPLGQIAARLISSPTGAELLTSDGQRYQAENAEALMPRVFGFGVPV
EECCCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCH
SRLAHWVQAAPPPGAEVRELDAAGRPALVIDQGWRVDYLEYPDTRARTLPTRVEVSRGDA
HHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCE
RIRLIIDQWELLQ
EEEEEECCCCCCC
>Mature Secondary Structure
MRPARRFLAALACVAGALLSACATPTPRAERAVLREVSAQFFLGGRMSASDGNQGASGRI
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
EWQHDTAGDEVTVYSPLGQIAARLISSPTGAELLTSDGQRYQAENAEALMPRVFGFGVPV
EECCCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCH
SRLAHWVQAAPPPGAEVRELDAAGRPALVIDQGWRVDYLEYPDTRARTLPTRVEVSRGDA
HHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCE
RIRLIIDQWELLQ
EEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA