Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 119896991

GI number: 119896991

Start: 746188

End: 747486

Strand: Reverse

Name: pkn1 [H]

Synonym: azo0700

Alternate gene names: 119896991

Gene position: 747486-746188 (Counterclockwise)

Preceding gene: 119896992

Following gene: 119896990

Centisome position: 17.08

GC content: 69.21

Gene sequence:

>1299_bases
ATGAACACGCTGCTGCATACCGCCGATCGCGGCGACGAACTCGACCGCGCCGCCTGGGCCCAGCGCTACCGCCGGGTGCG
CGACGCCAGCACCGACCTCTGTGCGCCGCTGGCGGTGGAGGACTACGTGATCCAGGCCTGCGAGGAAGCCAGCCCGGCGA
AATGGCACCTGGCGCATGTCAGCTGGTTCTTCGAAACCTTCATCCTCACCGAATACCTGCCCGGCTACAGCGAATTCCAT
CCGCGCTACCGACAGTTGTTCAACTCCTACTACCAGCAGATCGGGGAGGTCTTTCCGCGTGCCGCGCGCGGCACGCTGGC
ACGCCCGACCGTGGACGAAGTGCTGCGCTATCGCGCCCACGTGGATGCGGGGATGCTGGCGCTGCTGGCCGAACGCGCCG
ACCTGCCGTGGGCCGAAATCCTGCAGCGGCTGGAAATCGGCCTGAATCACGAGCAGCAGCACCAGGAACTGCTGCTCACC
GACATCAAGCGCAACTTCGCCGCCAACCCGTTGCGCCCCGCCTACCGGCTCGACCTGCCCCATCCTGCACAGCGCCCGCG
CGCGCCGCTGGAGTGGGTGAGCTTCGAGGGCGGGGTGTACGAGATCGGCGCCCCGGCGCTGGGCGAGCACTTCAGCTACG
ACAACGAAACGCCGCGCCACCGCGTCTATCTGCAGCCCTTCCGGCTCGCGTCGCGGCTGGTGACCAACGGCGAATTCCTC
GCCTTCATCGAATCCGGCGGTTATTCCAATCCCGCGCTATGGCTGGCGGACGGCTGGACCCAGGTGCGCAGCGCGGGCTG
GTCGGCGCCGCTGTACTGGGAGCGCATCGGCGGGGAATGGTGGCACTACACGCTGGGCGGCATGGCACCGCTGGCGCCGG
ACGAGCCGGTGTGCCACGTCAGCCACTACGAGGCCGCCGCCTACGCCGCCTGGGCCGGGCGGCGGCTGCCAACCGAAGCA
GAATGGGAGGTGGCCGCCGCCACGCAGCCGGTGGCCGGCAACCTGCGTGAAACCGGCCTCCTGCGGCCGACGGTGGCGCC
GGCCGGCGCCGGCCCCGCCCAACTCTACGGCGACGTCTGGGAGCACACCGGCTCCGCCTACCTGCCCTACCCCGGCTACC
ACGCCGCCGAAGGCGCGATCGGCGAATACAACGGCAAGTTCATGTGCAACCAGATGGTGCTGCGCGGCGGCTCCTGCGTC
ACCCCGGCCGACCACCTGCGCGCGACCTATCGCAACTTCTTCTATCCGCAGGAGCGCTGGCAATTCCAGGGGTTCCGCCT
GGCAGAGGACGCCACCTGA

Upstream 100 bases:

>100_bases
ACGCGACGCCTGAAACGGCCTGTCCGTCGGTGGCGATTTGACGGCCACCCGGGCCTCTGCTTTGCTGGAGCCAGGAAGCA
AAAAAACCGGGAGGGACGCC

Downstream 100 bases:

>100_bases
ACACCGCCGGCATGTCGGACGCTTTGACAGACCACGCCGAAAGGATGATTTTGAGCAGACTTTTACCCATTTAATCAGTG
CGTTATTAAAACGGCACGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNTLLHTADRGDELDRAAWAQRYRRVRDASTDLCAPLAVEDYVIQACEEASPAKWHLAHVSWFFETFILTEYLPGYSEFH
PRYRQLFNSYYQQIGEVFPRAARGTLARPTVDEVLRYRAHVDAGMLALLAERADLPWAEILQRLEIGLNHEQQHQELLLT
DIKRNFAANPLRPAYRLDLPHPAQRPRAPLEWVSFEGGVYEIGAPALGEHFSYDNETPRHRVYLQPFRLASRLVTNGEFL
AFIESGGYSNPALWLADGWTQVRSAGWSAPLYWERIGGEWWHYTLGGMAPLAPDEPVCHVSHYEAAAYAAWAGRRLPTEA
EWEVAAATQPVAGNLRETGLLRPTVAPAGAGPAQLYGDVWEHTGSAYLPYPGYHAAEGAIGEYNGKFMCNQMVLRGGSCV
TPADHLRATYRNFFYPQERWQFQGFRLAEDAT

Sequences:

>Translated_432_residues
MNTLLHTADRGDELDRAAWAQRYRRVRDASTDLCAPLAVEDYVIQACEEASPAKWHLAHVSWFFETFILTEYLPGYSEFH
PRYRQLFNSYYQQIGEVFPRAARGTLARPTVDEVLRYRAHVDAGMLALLAERADLPWAEILQRLEIGLNHEQQHQELLLT
DIKRNFAANPLRPAYRLDLPHPAQRPRAPLEWVSFEGGVYEIGAPALGEHFSYDNETPRHRVYLQPFRLASRLVTNGEFL
AFIESGGYSNPALWLADGWTQVRSAGWSAPLYWERIGGEWWHYTLGGMAPLAPDEPVCHVSHYEAAAYAAWAGRRLPTEA
EWEVAAATQPVAGNLRETGLLRPTVAPAGAGPAQLYGDVWEHTGSAYLPYPGYHAAEGAIGEYNGKFMCNQMVLRGGSCV
TPADHLRATYRNFFYPQERWQFQGFRLAEDAT
>Mature_432_residues
MNTLLHTADRGDELDRAAWAQRYRRVRDASTDLCAPLAVEDYVIQACEEASPAKWHLAHVSWFFETFILTEYLPGYSEFH
PRYRQLFNSYYQQIGEVFPRAARGTLARPTVDEVLRYRAHVDAGMLALLAERADLPWAEILQRLEIGLNHEQQHQELLLT
DIKRNFAANPLRPAYRLDLPHPAQRPRAPLEWVSFEGGVYEIGAPALGEHFSYDNETPRHRVYLQPFRLASRLVTNGEFL
AFIESGGYSNPALWLADGWTQVRSAGWSAPLYWERIGGEWWHYTLGGMAPLAPDEPVCHVSHYEAAAYAAWAGRRLPTEA
EWEVAAATQPVAGNLRETGLLRPTVAPAGAGPAQLYGDVWEHTGSAYLPYPGYHAAEGAIGEYNGKFMCNQMVLRGGSCV
TPADHLRATYRNFFYPQERWQFQGFRLAEDAT

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470977, Length=157, Percent_Identity=34.3949044585987, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38202250, Length=157, Percent_Identity=34.3949044585987, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI257470975, Length=149, Percent_Identity=34.8993288590604, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI194248087, Length=280, Percent_Identity=29.6428571428571, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI194248088, Length=286, Percent_Identity=29.020979020979, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 48908; Mature: 48908

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLLHTADRGDELDRAAWAQRYRRVRDASTDLCAPLAVEDYVIQACEEASPAKWHLAHV
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
SWFFETFILTEYLPGYSEFHPRYRQLFNSYYQQIGEVFPRAARGTLARPTVDEVLRYRAH
HHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHH
VDAGMLALLAERADLPWAEILQRLEIGLNHEQQHQELLLTDIKRNFAANPLRPAYRLDLP
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
HPAQRPRAPLEWVSFEGGVYEIGAPALGEHFSYDNETPRHRVYLQPFRLASRLVTNGEFL
CCCCCCCCCCCEEECCCCEEECCCCHHHHCCCCCCCCCCCEEEECHHHHHHHHHCCCCEE
AFIESGGYSNPALWLADGWTQVRSAGWSAPLYWERIGGEWWHYTLGGMAPLAPDEPVCHV
EEEECCCCCCCEEEEECCHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEE
SHYEAAAYAAWAGRRLPTEAEWEVAAATQPVAGNLRETGLLRPTVAPAGAGPAQLYGDVW
CHHHHHHHHHHHCCCCCCCCCCEEHHCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHH
EHTGSAYLPYPGYHAAEGAIGEYNGKFMCNQMVLRGGSCVTPADHLRATYRNFFYPQERW
HCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHH
QFQGFRLAEDAT
CCCCEEECCCCC
>Mature Secondary Structure
MNTLLHTADRGDELDRAAWAQRYRRVRDASTDLCAPLAVEDYVIQACEEASPAKWHLAHV
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
SWFFETFILTEYLPGYSEFHPRYRQLFNSYYQQIGEVFPRAARGTLARPTVDEVLRYRAH
HHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHH
VDAGMLALLAERADLPWAEILQRLEIGLNHEQQHQELLLTDIKRNFAANPLRPAYRLDLP
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
HPAQRPRAPLEWVSFEGGVYEIGAPALGEHFSYDNETPRHRVYLQPFRLASRLVTNGEFL
CCCCCCCCCCCEEECCCCEEECCCCHHHHCCCCCCCCCCCEEEECHHHHHHHHHCCCCEE
AFIESGGYSNPALWLADGWTQVRSAGWSAPLYWERIGGEWWHYTLGGMAPLAPDEPVCHV
EEEECCCCCCCEEEEECCHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCEEEE
SHYEAAAYAAWAGRRLPTEAEWEVAAATQPVAGNLRETGLLRPTVAPAGAGPAQLYGDVW
CHHHHHHHHHHHCCCCCCCCCCEEHHCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHH
EHTGSAYLPYPGYHAAEGAIGEYNGKFMCNQMVLRGGSCVTPADHLRATYRNFFYPQERW
HCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHH
QFQGFRLAEDAT
CCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]