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The map label for this gene is gloA1

Identifier: 119896983

GI number: 119896983

Start: 734887

End: 735363

Strand: Reverse

Name: gloA1

Synonym: azo0692

Alternate gene names: NA

Gene position: 735363-734887 (Counterclockwise)

Preceding gene: 119896984

Following gene: 119896975

Centisome position: 16.8

GC content: 65.41

Gene sequence:

>477_bases
ATGTCGCAGCGTCCGTTCAAGATCCTCGGCGTCCAGCAGATCGCCATCGGCGGCCCGAGCAAGGAAAAGCTCAAGACCTT
CTGGGTGGATATGCTGGGGCTGGAAGTCACCGGCAACTTCGTCTCGGAGCGCGAGAACGTGGACGAAGATATCTGCGCGA
TGGGCAAGGGGCCGTTCAAGGTGGAAGTCGACCTGATGCAACCGCTCGATCCCGAGAAGAAGCCCGCGGTGCATGCGACC
CCGCTCAATCACATCGGCCTGTGGGTGGATGATCTGCCGGTGGCGGTGGAATGGCTGACAGCGCAGGGCGTGCGCTTCGC
GCCGGGCGGCATCCGCCGCGGCGCCGCGGGCTATGACATCACCTTCCTGCACCCGAAGGGCAATGAGGAATTCCCGATCG
GCGGCGAGGGCGTGCTGGTGGAACTGGTGCAGGCACCGCCGGAGGTGGTCGAAGCCTTCGCCCGCCTCGCCGGCTGA

Upstream 100 bases:

>100_bases
CCGCCCCTCCGATCCCAGCCGTCTGTTCCGCTTCTCCTTTTCGCCGTTCTCGACTCCGCTATAATTATGAATTCTTAATC
CACTTCAGCAGGAGTTCCGC

Downstream 100 bases:

>100_bases
GACGGCCGGGCGGCCGTGCGCTCAGGGCGAGCGCGCGGCGAAGGTGTCGCAGGCCTGCAGGCTGCCGTGCTGCAGGCCGG
TGCGGAACCAGCGCACCCGC

Product: lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: Methylmalonyl-CoA Epimerase; Glyoxalase/Bleomycin Resistance Protein/Dioxygenase

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSQRPFKILGVQQIAIGGPSKEKLKTFWVDMLGLEVTGNFVSERENVDEDICAMGKGPFKVEVDLMQPLDPEKKPAVHAT
PLNHIGLWVDDLPVAVEWLTAQGVRFAPGGIRRGAAGYDITFLHPKGNEEFPIGGEGVLVELVQAPPEVVEAFARLAG

Sequences:

>Translated_158_residues
MSQRPFKILGVQQIAIGGPSKEKLKTFWVDMLGLEVTGNFVSERENVDEDICAMGKGPFKVEVDLMQPLDPEKKPAVHAT
PLNHIGLWVDDLPVAVEWLTAQGVRFAPGGIRRGAAGYDITFLHPKGNEEFPIGGEGVLVELVQAPPEVVEAFARLAG
>Mature_157_residues
SQRPFKILGVQQIAIGGPSKEKLKTFWVDMLGLEVTGNFVSERENVDEDICAMGKGPFKVEVDLMQPLDPEKKPAVHATP
LNHIGLWVDDLPVAVEWLTAQGVRFAPGGIRRGAAGYDITFLHPKGNEEFPIGGEGVLVELVQAPPEVVEAFARLAG

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 17156; Mature: 17025

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRPFKILGVQQIAIGGPSKEKLKTFWVDMLGLEVTGNFVSERENVDEDICAMGKGPFK
CCCCCEEEECEEEEEECCCCHHHHHHHHHHHHCEEEECCHHHHHCCCCHHHHHCCCCCEE
VEVDLMQPLDPEKKPAVHATPLNHIGLWVDDLPVAVEWLTAQGVRFAPGGIRRGAAGYDI
EEEEECCCCCCCCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEECCCCCCCCCCCCCE
TFLHPKGNEEFPIGGEGVLVELVQAPPEVVEAFARLAG
EEECCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
SQRPFKILGVQQIAIGGPSKEKLKTFWVDMLGLEVTGNFVSERENVDEDICAMGKGPFK
CCCCEEEECEEEEEECCCCHHHHHHHHHHHHCEEEECCHHHHHCCCCHHHHHCCCCCEE
VEVDLMQPLDPEKKPAVHATPLNHIGLWVDDLPVAVEWLTAQGVRFAPGGIRRGAAGYDI
EEEEECCCCCCCCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEECCCCCCCCCCCCCE
TFLHPKGNEEFPIGGEGVLVELVQAPPEVVEAFARLAG
EEECCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA