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The map label for this gene is ytfL1 [H]

Identifier: 119896974

GI number: 119896974

Start: 719709

End: 721004

Strand: Direct

Name: ytfL1 [H]

Synonym: azo0683

Alternate gene names: 119896974

Gene position: 719709-721004 (Clockwise)

Preceding gene: 119896973

Following gene: 119896976

Centisome position: 16.45

GC content: 66.28

Gene sequence:

>1296_bases
GTGGCGCTGCTCAACCACCTGCTGCTCATCCTGCTGCTGATCGCGGTCAGCGCCTTCTTCTCGCTCGCCGAAATCTCGCT
GGCGGCAGCGCGCAAGATCAAGCTCCAGCAACTGGCGGAAGAGGGCGTGGCCGACGCGCGGCGCGTACTGGCGCTGCAGG
AGAGCCCCGGCAGCTTCTTCACCGTGGTGCAGATCGCGCTCAACGCGGTCGCCATCCTCGGCGGCATCGTCGGCGAGCAG
GCGCTGTCGCCCTATGTGGAATCCGCGCTGCGCCCGTTCTACGACGGCCCCGCGCTCGGCACCGTCAGTTTCGTGATCGC
GTTCGTCTTCGTGACCTCGATGTTCGTGCTGCTGGCCGATCTGATGCCCAAGCGCCTGGCGATGGTGAAGCCCGAGGCGG
TGGCGATGCGGGTGGTGCGACCGATCCAGGCCAGCATGTGGCTGTTCGCGCCGCTGGTGTGGCTGTTCAACAGCCTGGCG
GACCGCCTGTTCGGGCTGTTCGGCGTGCCGAGCGCGCGCGCGGACGACATCACCTCGGACGACATCCTCGCGATGGCCGA
AGCCGGCACGCGCGCCGGCGCACTGCTGGAGCAGGAGCAGAACCTGATCCGCAACGTGTTCGAACTGGACGCCCGCATCG
TGCCGTCGGCGATGACCTCGCGCGACAGCGTCGTGTACTTCACGCTGGGCGAAGCCGAGGACAGCATCCGGCGCAAGATG
GCGGCGCATCCGCACGGCAAGTTCCCGGTGTGCGAGAGCGGCATCGACGACGTCATCGGCTACGTGGATGCGAAGGACCT
CTTCCGCCGCATCCTGCAGGGGCAGGACCTGTCGCTGCGCACCCAGCCGATCGTGCGCAAGGTGCTGATGCTGCCGGACA
CGCTGACACTGTTCGAGGCACTGGAGCGCTTCCGCGACGCCAAGGAGGACTTCGCGCTGGTGATCAGCGAGTACGCGCTG
GTGGTCGGCCTGCTGACGCTGCAGGACGTCATGAACACCGTGATGGGCGAACTCGGCAGCCCCTACCAGGAGGAACTGAT
CGTGCGCCGCGATGATTGCTCCTGGCTGATCGACGGCGTCACCCCGATCGAGGACGTGATGCAGGCGCTGGAGATCGAGG
TTTTCGAAGGCTTCGAGAACTACGAGACGATCGCCGGCTTTCTGATGTACCGGCTGCGCAAGGTGCCCAAGCGCACCGAC
TTCGTGGTCTACGCCGGCTACAAGTTCGAAGTGGTCGACATCGACAACTACCGCATCGACCAGGTGCTGGTGACGCGGGA
GCCCGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
TTTCGGGCCCGAGGGGGTTCTTGTTTGCGGCGGGCGAGGTGGCGGCGTCATGGCCGGGTGCTAGACTCGCCCGCGTCTCA
TTTCCCGCGCGGGAGCCTCC

Downstream 100 bases:

>100_bases
TCACCACAGCGATCGCCGCCGGGCCGCCCCAAGGCGATCGCGTGCCCCCTTGGGGGGTGAAGCAGGGGTTTCACGGAGCG
TTGCTCCGTGCCTGCGGAAC

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MALLNHLLLILLLIAVSAFFSLAEISLAAARKIKLQQLAEEGVADARRVLALQESPGSFFTVVQIALNAVAILGGIVGEQ
ALSPYVESALRPFYDGPALGTVSFVIAFVFVTSMFVLLADLMPKRLAMVKPEAVAMRVVRPIQASMWLFAPLVWLFNSLA
DRLFGLFGVPSARADDITSDDILAMAEAGTRAGALLEQEQNLIRNVFELDARIVPSAMTSRDSVVYFTLGEAEDSIRRKM
AAHPHGKFPVCESGIDDVIGYVDAKDLFRRILQGQDLSLRTQPIVRKVLMLPDTLTLFEALERFRDAKEDFALVISEYAL
VVGLLTLQDVMNTVMGELGSPYQEELIVRRDDCSWLIDGVTPIEDVMQALEIEVFEGFENYETIAGFLMYRLRKVPKRTD
FVVYAGYKFEVVDIDNYRIDQVLVTREPAAA

Sequences:

>Translated_431_residues
MALLNHLLLILLLIAVSAFFSLAEISLAAARKIKLQQLAEEGVADARRVLALQESPGSFFTVVQIALNAVAILGGIVGEQ
ALSPYVESALRPFYDGPALGTVSFVIAFVFVTSMFVLLADLMPKRLAMVKPEAVAMRVVRPIQASMWLFAPLVWLFNSLA
DRLFGLFGVPSARADDITSDDILAMAEAGTRAGALLEQEQNLIRNVFELDARIVPSAMTSRDSVVYFTLGEAEDSIRRKM
AAHPHGKFPVCESGIDDVIGYVDAKDLFRRILQGQDLSLRTQPIVRKVLMLPDTLTLFEALERFRDAKEDFALVISEYAL
VVGLLTLQDVMNTVMGELGSPYQEELIVRRDDCSWLIDGVTPIEDVMQALEIEVFEGFENYETIAGFLMYRLRKVPKRTD
FVVYAGYKFEVVDIDNYRIDQVLVTREPAAA
>Mature_430_residues
ALLNHLLLILLLIAVSAFFSLAEISLAAARKIKLQQLAEEGVADARRVLALQESPGSFFTVVQIALNAVAILGGIVGEQA
LSPYVESALRPFYDGPALGTVSFVIAFVFVTSMFVLLADLMPKRLAMVKPEAVAMRVVRPIQASMWLFAPLVWLFNSLAD
RLFGLFGVPSARADDITSDDILAMAEAGTRAGALLEQEQNLIRNVFELDARIVPSAMTSRDSVVYFTLGEAEDSIRRKMA
AHPHGKFPVCESGIDDVIGYVDAKDLFRRILQGQDLSLRTQPIVRKVLMLPDTLTLFEALERFRDAKEDFALVISEYALV
VGLLTLQDVMNTVMGELGSPYQEELIVRRDDCSWLIDGVTPIEDVMQALEIEVFEGFENYETIAGFLMYRLRKVPKRTDF
VVYAGYKFEVVDIDNYRIDQVLVTREPAAA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=384, Percent_Identity=26.0416666666667, Blast_Score=155, Evalue=1e-37,
Organism=Escherichia coli, GI1790664, Length=424, Percent_Identity=58.4905660377358, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI87082033, Length=233, Percent_Identity=34.7639484978541, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI145693175, Length=423, Percent_Identity=24.3498817966903, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788119, Length=238, Percent_Identity=28.1512605042017, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786879, Length=273, Percent_Identity=24.5421245421245, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47865; Mature: 47734

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLNHLLLILLLIAVSAFFSLAEISLAAARKIKLQQLAEEGVADARRVLALQESPGSFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TVVQIALNAVAILGGIVGEQALSPYVESALRPFYDGPALGTVSFVIAFVFVTSMFVLLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LMPKRLAMVKPEAVAMRVVRPIQASMWLFAPLVWLFNSLADRLFGLFGVPSARADDITSD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DILAMAEAGTRAGALLEQEQNLIRNVFELDARIVPSAMTSRDSVVYFTLGEAEDSIRRKM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCHHHHHHHH
AAHPHGKFPVCESGIDDVIGYVDAKDLFRRILQGQDLSLRTQPIVRKVLMLPDTLTLFEA
HCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHH
LERFRDAKEDFALVISEYALVVGLLTLQDVMNTVMGELGSPYQEELIVRRDDCSWLIDGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCEEECCC
TPIEDVMQALEIEVFEGFENYETIAGFLMYRLRKVPKRTDFVVYAGYKFEVVDIDNYRID
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECEEEEEEECCCCEEC
QVLVTREPAAA
EEEEECCCCCC
>Mature Secondary Structure 
ALLNHLLLILLLIAVSAFFSLAEISLAAARKIKLQQLAEEGVADARRVLALQESPGSFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH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EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]