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The map label for this gene is actP [H]

Identifier: 119896973

GI number: 119896973

Start: 717876

End: 719555

Strand: Direct

Name: actP [H]

Synonym: azo0682

Alternate gene names: 119896973

Gene position: 717876-719555 (Clockwise)

Preceding gene: 119896972

Following gene: 119896974

Centisome position: 16.4

GC content: 67.14

Gene sequence:

>1680_bases
ATGAACGCATCCCGCCTGTCCCGCCTGGCCCTCGGCCTGGCCTCGCTGCCACTGTCGGCCGCCGCCCTGGCCGCCGGCCC
CGCGATGGAAGCCGCGCAGAAGCAGCCGCTCAACCTGCACGCCATCGGCATGTTCTTCGTGTTCGTGCTGATGACCCTCG
GGATCACCTACTGGGCGGCCAGCCGCACCAAGTCGGCGTCCGATTTCTACACCGCCGGCGGTGGCATCACCGGCTTCCAG
AACGGCCTCGCGATCGCCGGCGACTACATGTCCGCCGCCACGCTGCTCGGCCTTACCGCGATGATGTACGCGCAGGGTGT
GGATGCCTACATCTACATGATCGCGTTCTTCGTCGGCTGGCCGATCATCCTGTTCCTGATGGCCGAACGCCTGCGCAACC
TGGGCAAGTTCACCTTCGCCGACATCACCGCCTACCGCCTCGACCAGGGCAAGGTGCGCACGATGGCGGCGGTCAGCTCG
CTGACCGTGGTGTGCTTCTACCTCGTCGCGCAGATGGTCGGCGCCGGCCAGCTGATCAAGCTGCTGTTCGGTCTGGACTA
CACCGTCGCGCTGTTCGTCGTCGGCGCGCTGATGATGGTCTACGTCACCTTCGGCGGCATGGTCGCCACCACCTGGGTGC
AGATCATCAAGGCCTGCATGCTGCTGCTCGGCGGCACCACCGTGATGCTGCTGGCGCTGAGCCAGTTCGGCTTCAGCTTC
GAGGCGCTGGCCACCCGCGCGATGGAAGTGCATAAGCTCGGACCCAAGCTGTTCAACCCGGGCAGCCTGCTCGCCGATCC
GGTCACCGCGATCTCGCTCGGCCTCGGCCTGATGTTCGGCACCGCGGGCCTGCCGCACATCCTGATGCGCTTCTTCACCG
TGACCGACGCCAAGGAAGCGCGCAAGTCGGTGCTCTACGCCTCGGGCATCATCGCCTACTTCTTCAACGTGATCGCGCTG
ATGGGCCTGGCCGCCATCCTGATCGTCGGCCAGAACCCGCAGTACTTCGAAGGCGGCGACCTCGCCGGCAAGATCGTCGG
CGGCGGCAACATGGTGGCGATGCACCTGGCGCACGCGGTGGGCGGCAACCTGCTGCTCGGCTTCCTGTCGGCGGTGGCCT
TCGCGACCATCCTCGCGGTGGTGGCCGGCCTGGCGCTGGCTGGTGCCTCGGCGATCTCCCACGACATCTACGCCCGCGTG
ATCATGAAGGGCCGCGCCTCGGAAACCACCGAGATCCGCGTCTCCAAGTTCGCCACCATCGGCCTCGGCGTGGTCGCGGT
GCTGCTCGGCATCGTGTTCGAGAAGATGAACGTCGCCTTCATGGTTGCGCTCGCCTTCGGTGTCGCCGCGTCCGCCAACT
TCCCGGTGCTGATCCTGTCGATGTACTGGAAGGGCCTGACCACCCGCGGCGCGCTTGCCGGCGGCTACCTCGGCCTGTTC
AGCGCGGTGACCTTCGTGGTGCTGTCGAAGTCGGTGTGGGTGGATGTGCTCGGCAACGCCGCGCCGATCTTCCCCTGGAC
GCAGCCGGCGCTGTTCTCGATGCCGCTCGCCTTCCTCGCCACCATCGTGGTGTCGCTGCTCGACTCCAGCCACAAGGCGC
GCAGCGAGCGCGAGGCCTTCGAAGACCAGTACGTGCGTGCGCAGACCGGTGTCGGCGCCGCCAGCGCCGCCGCGCACTAA

Upstream 100 bases:

>100_bases
TTTTCTGGGTGCTGACCTTCGTCTATGTGCGCCGCGCCAACGGCGAGTTCGACGCGATCAACACCGAGATCGTCCGCGCC
GCCTGGCAGGAGGAGAAGTA

Downstream 100 bases:

>100_bases
GCCGCGTCGCTGCACACCCCGGCCGCCATGTGCGGCCCCGAACCCCCTCCGGCTTTCGGGCCCGAGGGGGTTCTTGTTTG
CGGCGGGCGAGGTGGCGGCG

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MNASRLSRLALGLASLPLSAAALAAGPAMEAAQKQPLNLHAIGMFFVFVLMTLGITYWAASRTKSASDFYTAGGGITGFQ
NGLAIAGDYMSAATLLGLTAMMYAQGVDAYIYMIAFFVGWPIILFLMAERLRNLGKFTFADITAYRLDQGKVRTMAAVSS
LTVVCFYLVAQMVGAGQLIKLLFGLDYTVALFVVGALMMVYVTFGGMVATTWVQIIKACMLLLGGTTVMLLALSQFGFSF
EALATRAMEVHKLGPKLFNPGSLLADPVTAISLGLGLMFGTAGLPHILMRFFTVTDAKEARKSVLYASGIIAYFFNVIAL
MGLAAILIVGQNPQYFEGGDLAGKIVGGGNMVAMHLAHAVGGNLLLGFLSAVAFATILAVVAGLALAGASAISHDIYARV
IMKGRASETTEIRVSKFATIGLGVVAVLLGIVFEKMNVAFMVALAFGVAASANFPVLILSMYWKGLTTRGALAGGYLGLF
SAVTFVVLSKSVWVDVLGNAAPIFPWTQPALFSMPLAFLATIVVSLLDSSHKARSEREAFEDQYVRAQTGVGAASAAAH

Sequences:

>Translated_559_residues
MNASRLSRLALGLASLPLSAAALAAGPAMEAAQKQPLNLHAIGMFFVFVLMTLGITYWAASRTKSASDFYTAGGGITGFQ
NGLAIAGDYMSAATLLGLTAMMYAQGVDAYIYMIAFFVGWPIILFLMAERLRNLGKFTFADITAYRLDQGKVRTMAAVSS
LTVVCFYLVAQMVGAGQLIKLLFGLDYTVALFVVGALMMVYVTFGGMVATTWVQIIKACMLLLGGTTVMLLALSQFGFSF
EALATRAMEVHKLGPKLFNPGSLLADPVTAISLGLGLMFGTAGLPHILMRFFTVTDAKEARKSVLYASGIIAYFFNVIAL
MGLAAILIVGQNPQYFEGGDLAGKIVGGGNMVAMHLAHAVGGNLLLGFLSAVAFATILAVVAGLALAGASAISHDIYARV
IMKGRASETTEIRVSKFATIGLGVVAVLLGIVFEKMNVAFMVALAFGVAASANFPVLILSMYWKGLTTRGALAGGYLGLF
SAVTFVVLSKSVWVDVLGNAAPIFPWTQPALFSMPLAFLATIVVSLLDSSHKARSEREAFEDQYVRAQTGVGAASAAAH
>Mature_559_residues
MNASRLSRLALGLASLPLSAAALAAGPAMEAAQKQPLNLHAIGMFFVFVLMTLGITYWAASRTKSASDFYTAGGGITGFQ
NGLAIAGDYMSAATLLGLTAMMYAQGVDAYIYMIAFFVGWPIILFLMAERLRNLGKFTFADITAYRLDQGKVRTMAAVSS
LTVVCFYLVAQMVGAGQLIKLLFGLDYTVALFVVGALMMVYVTFGGMVATTWVQIIKACMLLLGGTTVMLLALSQFGFSF
EALATRAMEVHKLGPKLFNPGSLLADPVTAISLGLGLMFGTAGLPHILMRFFTVTDAKEARKSVLYASGIIAYFFNVIAL
MGLAAILIVGQNPQYFEGGDLAGKIVGGGNMVAMHLAHAVGGNLLLGFLSAVAFATILAVVAGLALAGASAISHDIYARV
IMKGRASETTEIRVSKFATIGLGVVAVLLGIVFEKMNVAFMVALAFGVAASANFPVLILSMYWKGLTTRGALAGGYLGLF
SAVTFVVLSKSVWVDVLGNAAPIFPWTQPALFSMPLAFLATIVVSLLDSSHKARSEREAFEDQYVRAQTGVGAASAAAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=525, Percent_Identity=22.8571428571429, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1790503, Length=546, Percent_Identity=58.7912087912088, Blast_Score=651, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=461, Percent_Identity=25.3796095444685, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58858; Mature: 58858

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASRLSRLALGLASLPLSAAALAAGPAMEAAQKQPLNLHAIGMFFVFVLMTLGITYWAA
CCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SRTKSASDFYTAGGGITGFQNGLAIAGDYMSAATLLGLTAMMYAQGVDAYIYMIAFFVGW
CCCCCCCCCEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
PIILFLMAERLRNLGKFTFADITAYRLDQGKVRTMAAVSSLTVVCFYLVAQMVGAGQLIK
HHHHHHHHHHHHHCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LLFGLDYTVALFVVGALMMVYVTFGGMVATTWVQIIKACMLLLGGTTVMLLALSQFGFSF
HHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHH
EALATRAMEVHKLGPKLFNPGSLLADPVTAISLGLGLMFGTAGLPHILMRFFTVTDAKEA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHH
RKSVLYASGIIAYFFNVIALMGLAAILIVGQNPQYFEGGDLAGKIVGGGNMVAMHLAHAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHH
GGNLLLGFLSAVAFATILAVVAGLALAGASAISHDIYARVIMKGRASETTEIRVSKFATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GLGVVAVLLGIVFEKMNVAFMVALAFGVAASANFPVLILSMYWKGLTTRGALAGGYLGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHH
SAVTFVVLSKSVWVDVLGNAAPIFPWTQPALFSMPLAFLATIVVSLLDSSHKARSEREAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EDQYVRAQTGVGAASAAAH
HHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MNASRLSRLALGLASLPLSAAALAAGPAMEAAQKQPLNLHAIGMFFVFVLMTLGITYWAA
CCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SRTKSASDFYTAGGGITGFQNGLAIAGDYMSAATLLGLTAMMYAQGVDAYIYMIAFFVGW
CCCCCCCCCEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
PIILFLMAERLRNLGKFTFADITAYRLDQGKVRTMAAVSSLTVVCFYLVAQMVGAGQLIK
HHHHHHHHHHHHHCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LLFGLDYTVALFVVGALMMVYVTFGGMVATTWVQIIKACMLLLGGTTVMLLALSQFGFSF
HHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHH
EALATRAMEVHKLGPKLFNPGSLLADPVTAISLGLGLMFGTAGLPHILMRFFTVTDAKEA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHH
RKSVLYASGIIAYFFNVIALMGLAAILIVGQNPQYFEGGDLAGKIVGGGNMVAMHLAHAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHH
GGNLLLGFLSAVAFATILAVVAGLALAGASAISHDIYARVIMKGRASETTEIRVSKFATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GLGVVAVLLGIVFEKMNVAFMVALAFGVAASANFPVLILSMYWKGLTTRGALAGGYLGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHH
SAVTFVVLSKSVWVDVLGNAAPIFPWTQPALFSMPLAFLATIVVSLLDSSHKARSEREAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EDQYVRAQTGVGAASAAAH
HHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA