Click here to switch to the map view.

The map label for this gene is gox [H]

Identifier: 119896900

GI number: 119896900

Start: 637000

End: 638121

Strand: Direct

Name: gox [H]

Synonym: azo0609

Alternate gene names: 119896900

Gene position: 637000-638121 (Clockwise)

Preceding gene: 119896899

Following gene: 119896910

Centisome position: 14.56

GC content: 73.17

Gene sequence:

>1122_bases
ATGCCTGAGGCCGGCAAGCCTGCCCAGCGCCTTGCCGCCATCCCGCGCGAGATCGCGGCGGTCGCCGACTACGAGCGTTT
CTCGCGCGCCAGCCTGGACGACAACGCCTGGGCTTATCTGCACAGCGCCGCCGCCGACGAGCTGAGCTGGCGCTGGAACC
GCGAGGCCTACGACCGCCTGCGCATCCTGCCGCGCGTGCTGCGCGACGTCACTGCCGGCCACACCCGCTGCAGCCTGCCC
GGGCTGGAGCTGGCCCACCCCATCCTGCTGGCGCCGGTGGCCTGGCAGAAGCTGTTCCATCCCGACGGTGAACGCGCCAG
CGCCTATGCCGCGGCGGCGCTCGACACCGGCCTGGTGCTGAGCACGCTGTCCAGTTACACGCTGGAAGAGGTCGCCGCGG
TCGGCGCCGGGCCGCGCTGGTTCCAGCTCTACCTGCAGCCGGACCGCGGCGTGTCGCGCGCGCTGGTCGAGCGTGCCGAG
CGTGCCGGCTACAGCGGCATCGTGTTCACCATCGACGCGCCGCTCAATGGCGTGCGCAACCGCGAACACCGCGCCGGCTT
CCAGCTGCCGCCGGGCGTCGATTCCGCCAACCTGCGCGGCGCGCCTGCGCCCGTGCGGCCGGCGCTGGGCGAGCACGACA
GCGCGGTGTTCCAGGGCCTGATGCGCGAGGCGCCAACCTGGCGGGACGTCGAATGGCTGTCCGGGATCACCCGGCTGCCG
GTCATTCTGAAAGGCGTATTGCATCCGGAGGATGCCCGCATCGCCGCCGATCTCGGCGCCGCCGGGCTCATCGTCTCCAA
CCACGGCGGCCGCACGCTGGACACCCTGCCGCCGGCGCTGGAGATGTTGCCGGCGATGGCGGATGCCGTCGGCGACCGCG
TTGCGCTGCTGCTCGATGGCGGTATCCGTCGCGGCAGCGATGTGTTCAAGGCGATCGCGCTCGGCGCGCGCGCGGTGCTG
GTGGGGCGCGGCTATATCCACGCACTCGCCGCCGCCGGACCGCTCGGCGTCGCCCACGTCATCCGCCTGCTGCGCGACGA
GCTGGAAGTGGCGATGGCGCTCGCCGGCTGCGCGACGCTGGCGGACATCGGGCCGCAGGCGCTGCTGGCGGCCCCGCGCT
GA

Upstream 100 bases:

>100_bases
GACATGGCGCTGCTGCAACTGCGCCAGAGTGTCGGGGAGGACAACGACGCCGTCGTGCGCCTCACCGGCACCTATCACAA
CCTGCTGCGCCTGTGGGCCG

Downstream 100 bases:

>100_bases
GCGGGCTGCCTCAGCCGCCCGCCGCCATCGAGTTCTCCGCCCGCCAGCCGCCCCCGAGCGCCTTGTACAGCCCGACCGCA
TCGGTCAACCGCGCCTGGCG

Product: (S)-2-hydroxy-acid oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPEAGKPAQRLAAIPREIAAVADYERFSRASLDDNAWAYLHSAAADELSWRWNREAYDRLRILPRVLRDVTAGHTRCSLP
GLELAHPILLAPVAWQKLFHPDGERASAYAAAALDTGLVLSTLSSYTLEEVAAVGAGPRWFQLYLQPDRGVSRALVERAE
RAGYSGIVFTIDAPLNGVRNREHRAGFQLPPGVDSANLRGAPAPVRPALGEHDSAVFQGLMREAPTWRDVEWLSGITRLP
VILKGVLHPEDARIAADLGAAGLIVSNHGGRTLDTLPPALEMLPAMADAVGDRVALLLDGGIRRGSDVFKAIALGARAVL
VGRGYIHALAAAGPLGVAHVIRLLRDELEVAMALAGCATLADIGPQALLAAPR

Sequences:

>Translated_373_residues
MPEAGKPAQRLAAIPREIAAVADYERFSRASLDDNAWAYLHSAAADELSWRWNREAYDRLRILPRVLRDVTAGHTRCSLP
GLELAHPILLAPVAWQKLFHPDGERASAYAAAALDTGLVLSTLSSYTLEEVAAVGAGPRWFQLYLQPDRGVSRALVERAE
RAGYSGIVFTIDAPLNGVRNREHRAGFQLPPGVDSANLRGAPAPVRPALGEHDSAVFQGLMREAPTWRDVEWLSGITRLP
VILKGVLHPEDARIAADLGAAGLIVSNHGGRTLDTLPPALEMLPAMADAVGDRVALLLDGGIRRGSDVFKAIALGARAVL
VGRGYIHALAAAGPLGVAHVIRLLRDELEVAMALAGCATLADIGPQALLAAPR
>Mature_372_residues
PEAGKPAQRLAAIPREIAAVADYERFSRASLDDNAWAYLHSAAADELSWRWNREAYDRLRILPRVLRDVTAGHTRCSLPG
LELAHPILLAPVAWQKLFHPDGERASAYAAAALDTGLVLSTLSSYTLEEVAAVGAGPRWFQLYLQPDRGVSRALVERAER
AGYSGIVFTIDAPLNGVRNREHRAGFQLPPGVDSANLRGAPAPVRPALGEHDSAVFQGLMREAPTWRDVEWLSGITRLPV
ILKGVLHPEDARIAADLGAAGLIVSNHGGRTLDTLPPALEMLPAMADAVGDRVALLLDGGIRRGSDVFKAIALGARAVLV
GRGYIHALAAAGPLGVAHVIRLLRDELEVAMALAGCATLADIGPQALLAAPR

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=366, Percent_Identity=37.7049180327869, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI54234014, Length=348, Percent_Identity=36.4942528735632, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI7705393, Length=348, Percent_Identity=36.4942528735632, Blast_Score=237, Evalue=1e-62,
Organism=Escherichia coli, GI1790033, Length=378, Percent_Identity=35.4497354497354, Blast_Score=209, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI193208036, Length=356, Percent_Identity=35.6741573033708, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI32566217, Length=267, Percent_Identity=34.4569288389513, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323587, Length=368, Percent_Identity=32.8804347826087, Blast_Score=204, Evalue=1e-53,
Organism=Drosophila melanogaster, GI78707188, Length=355, Percent_Identity=43.6619718309859, Blast_Score=271, Evalue=5e-73,
Organism=Drosophila melanogaster, GI281363140, Length=355, Percent_Identity=43.6619718309859, Blast_Score=270, Evalue=8e-73,
Organism=Drosophila melanogaster, GI78707190, Length=355, Percent_Identity=43.6619718309859, Blast_Score=270, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 39806; Mature: 39675

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAGKPAQRLAAIPREIAAVADYERFSRASLDDNAWAYLHSAAADELSWRWNREAYDRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
RILPRVLRDVTAGHTRCSLPGLELAHPILLAPVAWQKLFHPDGERASAYAAAALDTGLVL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
STLSSYTLEEVAAVGAGPRWFQLYLQPDRGVSRALVERAERAGYSGIVFTIDAPLNGVRN
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
REHRAGFQLPPGVDSANLRGAPAPVRPALGEHDSAVFQGLMREAPTWRDVEWLSGITRLP
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VILKGVLHPEDARIAADLGAAGLIVSNHGGRTLDTLPPALEMLPAMADAVGDRVALLLDG
HHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEECC
GIRRGSDVFKAIALGARAVLVGRGYIHALAAAGPLGVAHVIRLLRDELEVAMALAGCATL
CCCCHHHHHHHHHHCCHHEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADIGPQALLAAPR
HHCCCHHHCCCCC
>Mature Secondary Structure 
PEAGKPAQRLAAIPREIAAVADYERFSRASLDDNAWAYLHSAAADELSWRWNREAYDRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
RILPRVLRDVTAGHTRCSLPGLELAHPILLAPVAWQKLFHPDGERASAYAAAALDTGLVL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
STLSSYTLEEVAAVGAGPRWFQLYLQPDRGVSRALVERAERAGYSGIVFTIDAPLNGVRN
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
REHRAGFQLPPGVDSANLRGAPAPVRPALGEHDSAVFQGLMREAPTWRDVEWLSGITRLP
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VILKGVLHPEDARIAADLGAAGLIVSNHGGRTLDTLPPALEMLPAMADAVGDRVALLLDG
HHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEECC
GIRRGSDVFKAIALGARAVLVGRGYIHALAAAGPLGVAHVIRLLRDELEVAMALAGCATL
CCCCHHHHHHHHHHCCHHEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADIGPQALLAAPR
HHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA